Curator Dashboard

Biobank and Pathology Core provides resources for human biospecimen-based research to be used to study causes, detection, prevention, and treatment of cancer.Central facility for the collection, processing, storage, and distribution of fresh, frozen, and FFPE-processed human biospecimens (tissues, blood, bone marrow, urine, and other liquid samples) for research use. Core also serves as national resource, as evidenced by the several hundred samples from multiple tumor types that have been provided to the Cancer Genome Atlas (TCGA) and NCI’s CPTAC proteogenomic consortium. Histology Service within the Core facilitates selection of appropriate specimens for tissue analyses and provides the basic services of cutting, dissecting, and staining of fresh-frozen and formalin-fixed, paraffin-embedded tissues. It includes construction of tissue microarray blocks and laser capture microdissection for isolation of pure cell populations and tumor cell enrichment. The Core’s Immunohistochemistry Service provides immunostaining using optimized antibodies for clinico-pathologic research studies.

• Resource
• RRID
• 2 months ago - submitted by Patrick Badua

Core provides support for early discovery and in vivo testing of antitumor detection and therapeutic agents. Provides resources, professional and technical expertise, and advisory services related to evaluation of agents with potential diagnostic or therapeutic activity. ATA Core works closely with investigators to establish preclinical models, including Patient-Derived Xenograft (PDX) and Patient-Derived Organoid (PDO) models, for the design and execution of pharmacokinetic (PK), toxicity, and in vivo efficacy studies. Assists investigators in determining the best formulation, administration route, and treatment schedule for each new compound, either alone or in combination with other agents.

• Resource
• RRID
• 2 months ago - submitted by Patrick Badua

Core provides bioinformatics support services including creating and maintaining repository of bioinformatics pipelines, providing customized data analysis support, assisting computational researchers in their research efforts, and training staff in computational and bioinformatics techniques. Provides bioinformatics software applications and pipelines for experimental assays ranging from standard genomics pipelines like RNAseq and variant detection to the growing demand for single-cell processing workflows and new spatial-based assays in transcriptomics and proteomics. Provides training and consulatation.

• Resource
• RRID
• 2 months ago - submitted by Patrick Badua

Web application for human-readable, searchable neuroimaging datasets using universally accessible JSON format and URL-based RESTful APIs. NeuroJSON.io is built upon highly scalable document-store NoSQL database technologies, specifically, open-source Apache CouchDB engine, that can handle millions of datasets without major performance penalties. Provides fine-grained data search capabilities to allow users to find, preview and re-combine complex data records from public datasets before download.

• Resource
• RRID
• 2 months ago - by Anonymous

Software C library for SASA calculations that provides both command-line and Python interfaces in addition to its C API. Used for Solvent-Accessible Surface Area analysis.

• Resource
• RRID
• 2 months ago - by Anonymous

Web server for predicting interacting sites on protein surfaces. Analyzes solvent-accessible residues likely to participate in PPIs.Predicts interacting amino acid residues in proteins that are most likely to interact with other proteins, given the 3D structures of subunits of protein complex.

• Resource
• RRID
• 2 months ago - by Anonymous

Web allosteric site prediction tool. Web server designed for prediction and visualization of protein allosteric sites, which are crucial locations on proteins for regulating their function and key targets for drug development. Helps researchers identify these regulatory sites on proteins, supporting efforts in allosteric drug discovery by analyzing protein structures from Protein Data Bank.

• Resource
• RRID
• 2 months ago - by Anonymous

Software standalone package for protein-protein and protein-DNA/RNA docking based on hybrid algorithm of template-based modeling and ab initio free docking.

• Resource
• RRID
• 2 months ago - by Anonymous

Software R package uses published biomarker algorithms to calculate three biological aging measures: Klemera-Doubal Method (KDM) biological age, phenotypic age, and homeostatic dysregulation. Used to quantify biological aging based on analysis of chronological age and mortality risk.

• Resource
• RRID
• 2 months ago - by Anonymous

Software neuroscience library for Python, intended to complement the existing nibabel library. Can automatic download data and interpret them into Python data structures.

• Resource
• RRID
• 2 months ago - by Anonymous

Multimode microplate reader for luminescence, fluorescence (top/bottom), and absorbance, featuring dual filter wheels, expanded temp control, and integrated software for real-time kinetics.

• Resource
• RRID
• 2 months ago - by Anonymous

World-renowned institution dedicated to ending cancer through expert, compassionate patient care, pioneering research, and education for adults and children with all types of cancer, combining cutting-edge science with a holistic approach to treatment and support. Its mission focuses on innovative diagnosis and treatment (surgery, chemo, radiation, immunotherapy), supportive care (nursing, counseling, rehab), and training future cancer leaders.

• Resource
• RRID
• 2 months ago - submitted by Edyta Vieth

Core provides biostatistical review of grant applications, offering clear, practical feedback on feasibility and statistical rigor to investigators and review panels. We support investigators across the research lifecycle, from grant proposal development and clinical protocol design to laboratory, animal, and epidemiologic study planning. Services also include short-term consultations, study monitoring, data analysis, manuscript preparation, and responses to peer review.

• Resource
• RRID
• 2 months ago - by Anonymous

Web based platform for exploring full brain connectomic datasets. Used for exploring and analyzing large connectomics datasets.

• Resource
• RRID
• 2 months ago - by Anonymous

High-resolution mass spectrometer with ion mobility, designed for deep, accurate analysis of complex samples across life science and analytical chemistry research. System adds Ion Mobility Separation to the original SYNAPT G2's high-resolution QuanTof technology, offering a third dimension of separation (size/shape) for superior selectivity, sensitivity, and structural insight in complex samples, beyond just mass and chromatography. The G2-Si integrates StepWave optics and enhanced data workflows for better performance in proteomics, metabolomics, and biomarker discovery.

• Resource
• RRID
• 2 months ago - by Anonymous

Software set of programs and utilities for working on SAM/BAM files.

• Resource
• RRID
• 2 months ago - by Anonymous

Imaging system is confocal imaging platform designed for high-throughput biological assays. Supports phenotypic screening and imaging of complex biological models, including live cells, primary cells, and microtissues.

• Resource
• RRID
• 2 months ago - by Anonymous

American company in the life sciences and diagnostics business that is focused on selling to the pharmaceutical and biotechnology industries, especially in relation to approaches making use of new cell therapy or gene therapy developments.

• Resource
• RRID
• 2 months ago - by Anonymous

Software R package contains functions, data sets, examples, demos, and vignettes for the book Christian Kleiber and Achim Zeileis (2008), Applied Econometrics with R, Springer-Verlag, New York. ISBN 978-0-387-77316-2.

• Resource
• RRID
• 2 months ago - submitted by Jules Cazaubiel

Facility for Imaging and Brain Research houses 3T Siemens Prisma scanner, mock scanner, and data analysis facilities. Research dedicated MRI scanning facility designed to suit wide range of basic and translational research programs by researchers across the UCI campus and beyond.

• Resource
• RRID
• 2 months ago - submitted by Zhiqun Tan