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Core used to develop custom monoclonal antibodies and obtain large scale quantities of existing ones for experiments. Core provides cell line distribution service and tests samples for mycoplasma contamination.
this is a test please delete
Testing this system only delete this
Inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats. Inhibitor of mitochondrial electron transport. Neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Paclitaxel has been used to study its effects on tumor regression in mouse models of pancreatic ductal adenocarcinoma[1]. Paclitaxel has also been used as an internal standard for chromatographic assays of docetaxel[3]. Furthermore, paclitaxel has been used to analyze its effects on Caenorhabditis elegans embryos[2].
Collaborative venture between the National Institute of Mental Health (NIMH) and several academic institutions. Repository facilitates psychiatric genetic research by providing patient and control samples and phenotypic data for wide-range of mental disorders and Stem Cells.Stores biosamples, genetic, pedigree and clinical data collected in designated NIMH-funded human subject studies. RGR database likewise links to other repositories holding data from same subjects, including dbGAP, GEO and NDAR. Allows to access these data and biospecimens (e.g., lymphoblastoid cell lines, induced pluripotent cell lines, fibroblasts) and further expand genetic and molecular characterization of patient populations with severe mental illness.
HNPP is a fluorescent substrate for alkaline phosphatase that enables sensitive detection of biomolecules. Upon dephosphorylation, HNPP produces a strongly fluorescent precipitate on membranes with a maximum of absorbance at 290nm and a maximum of fluorescence emission at 509nm. The dephosphorylated form of HNPP, HNP, alone possesses weak affinity to tissues and chromosome preparations. For in situ applications HNPP is coupled with the diazonium salt Fast Red TR.
Software tool as a digital virtual microscope for viewing and moving scanned histological slides and for making annotations and measurements on them. Used in digital pathology. Helps to simplify the areas of the pathology workflow where imaging, slide digitization, storage, archivation, visualization and analysis are performed.
Extending the Cox Model is aimed at researchers, practitioners, and graduate students who have some exposure to traditional methods of survival analysis. The emphasis is on semiparametric methods based on the proportional hazards model. The inclusion of examples with SAS and S-PLUS code will make the book accessible to most working statisticians.
Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning.
Singularity Hub is an open source, free to use registry for Singularity containers. It hosts over 1000 container collections and is available at https://www.singularity-hub.org.
Commercially available software for visualization and analysis of next generation sequencing data. Used for viewing, exploring, and sharing of NGS analysis results. Complete toolkit for genomics, transcriptomics, epigenomics, and metagenomics in one program.
This is a colony of mice that was derived from B6SJL-Tg(SOD1*G93A)1Gur/J mice initially sourced from Jackson Laboratories. These are used as an animal model of motor neuron degeneration.
The LIVE/DEAD™ Fixable Aqua Dead Cell Stain Kit is used to determine the viability of cells prior to the fixation and permeabilization required for intracellular antibody staining or prior to elimination of biohazardous materials using formaldehyde fixation. This kit has been optimized and validated for use with a violet laser flow cytometer.
The LIVE/DEAD™ Fixable Near-IR Dead Cell Stain Kit is used to determine the viability of cells prior to the fixation and permeabilization required for intracellular antibody staining or prior to elimination of biohazardous materials using formaldehyde fixation. This kit has been optimized and validated for use with a red laser flow cytometer.
Software suite for image acquisition and analysis. The software can be paired with high-quality cameras to maximize output quality and export it for sharing and research applications.
Total RNA and small/miRNA from TRIzol without phase separation
An in vitro qPCR mastermix using SYBR green detection methods to measure DNA amplification and relative expression of genes.
An in vitro cDNA synthesis kit used for synthesis of single stranded cDNA from whole tissue/embryo RNA
An in vitro capped transcription kit used to transcribe open reading frames downstream of SP6 promoter.