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Core provides instruments including Becton-Dickinson FACSCelesta or ACEA NovoCyte flow cytometer for use after training . Pathology core staff member is assigned to support instruments, answer questions, and, offer on-demand hardware, software, fluidics and technical expertise. Instrument users must ultimately run their own samples and be responsible for technical and scientific legitimacy of their experiments.
Core offers instruments including Reichert-Jung Polycut microtome for decalcified or undecalcified samples, Reichert-Jung rotary microtomes for decalcified specimens, diamond band saws, cryostats for frozen sections with special features for bone section, slow speed diamond saws, high speed grinding cutoff wheel, precision grinding and polishing machines (Buehler Automet 300),complete embedding and preparation equipment and supplies for paraffin, methacrylate, epoxy, and other resins for embedding of biologic specimens, automated tissue processor for plastic and paraffin embedding preparation (Leica ASP 300S)
Core identifies bio-markers using medical imaging that provides insight into disease processes, treatment options, and outcome variability.
Core allows researchers to generate high resolution tomographic data of bone, fossils, and contrast enhanced tissues. These data can include 3D surface visualizations of anatomy and morphology, that can facilitate morphometric studies, phylogenetics analysis, and biomechanics modelling.
Core provides services for acquiring three-dimensional imaging and quantitative analysis of biological and engineered structures/materials. The core is capable of imaging mineralized tissues (e.g., bone, teeth) and soft tissues (e.g., tendons, ligaments, cartilage, blood vessels, muscle) with the aid of radiographic contrast agents. This core is managed and operated by members of the Orthopaedic Research Laboratories.
Core accommodates mass spectrometers (ICP-MS) – Quadrupole ICP-MS and High-Resolution ICP-MS. Provides solution-based elemental analysis on variety of materials from rock through to natural waters in concentration ranges from ppm to ppt in biological, environmental, geological and industrial materials.
Facility dedicated to micron and nanoscale imaging and analysis of materials. The center, housed in Building 22 of the North Campus Research Complex, provides instruments and professional training.
Islet Core provides consultative advice and equipment and services for isolation and study of pancreatic islet structure and function in support of diabetes-related research.
Core supports investigators interested in assays related to diabetes, heart disease, and hypertension. Analytical methods include general blood chemistry, chemiluminescence, immunoassay, radioimmunoassay, multiplexing, and ELISA.
MCDB Imaging Facility in the Biological Sciences Building provides microscopes available to any University of Michigan researcher. Access to scope time granted after appropriate training. Provides microscope equipment, image capture systems, software to assist researchers with their sample imaging.
Core dedicated to developing technology to harness abundant, clean, and renewable marine energy in environmentally sustainable way and at competitive cost.
Research facility dedicated to the study and testing of various marine and hydrodynamic phenomena. It is part of the Department of Naval Architecture and Marine Engineering at the University of Michigan. Conducts research and experiments related to fluid dynamics, ship design, offshore engineering, and other areas relevant to marine and naval architecture.
Lurie Nanofabrication Facility serves technology educators and creators through broad access to advanced nanofabrication equipment and staff expertise in safe, collaborative environment. Equipment and processes are available for research on silicon integrated circuits, MEMS, III-V compound devices, organic devices and nanoimprint technology. We also encourage researchers from non-traditional disciplines to make use of our processes, such as metal and dielectric coatings, vacuum processes, fabrication of micro and nano components and metrology tools.
Core specializes in precise measurements of rare isotopologues such as “clumped” isotopes of carbonate and CO2 and triple oxygen isotope distributions in waters, carbonates, phosphates and recently organics. Houses Nu Perspective IRMS mass spectrometers, EuroVector EA3000 and HT-PyrOH, NuCarb device for traditional carbon and oxygen isotopes, Thermo Fisher ISQ 7000 GC-MS, fully automated clumped isotope preparation line, semi-automated triple oxygen isotope preparation line, manual water fluorination line, multi-purpose vacuum extraction line, and ovens, balances, glassware, fume hoods, and other equipment used in experiments and sample preparation.
Integrated Public Use Microdata Series Health Surveys provide free individual-level survey data for research purposes from two leading sources of self-reported health and health care access information: the National Health Interview Survey (NHIS) and the Medical Expenditure Panel Survey (MEPS).
Provides information about the National Health Interview Survey (NHIS) data collection, its participants, and its protocols. It also provides analytic notes and references. They will help you understand, analyze, and us.e NHIS data.
CFX Connect Real-Time PCR System provides excellent thermal performance for two-target multiplex PCR and routine detection of single fluorophore experiments.
Web application for nonlinear refinement of image registration after WebAlign.
Web application for 2D image registration to 3D atlas. Used for user guided affine spatial registration (anchoring) of sectional image data, typically high resolution histological images, to 3D reference atlas space. Can generate user defined cut planes through atlas templates that match orientation of cutting plane of 2D experimental images (atlas maps).
Core provides facility to conduct experimental research on neutron irradiated materials in aqueous environments. The IMTL consists of five refreshed autoclaves that can be mounted in constant extension rate or crack growth rate configurations. Capable of conducting experiments on stress corrosion cracking of neutron irradiated material in supercritical water.