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High-performance computing facility. Its resources have been designed to support labs engaged in genetics and bioinformatics research, but are open to anyone on campus. The Stanford SCG Bioinformatics Cluster is optimized to support large memory, single-node threaded applications as well as applications and workflows that require many small files.
Software R package provides two methods of plotting categorical scatter plots such that arrangement of points within category reflects the density of data at that region, and avoids over-plotting. Categorical Scatter (Violin Point) Plots.
Software R package to convert statistical analysis objects from R into tidy format. Summarizes key information about statistical objects in tidy tibbles. This makes it easy to report results, create plots and consistently work with large numbers of models at once.
Code to analyse data from "Conserved pan-cancer microenvironment subtypes predict response to immunotherapy" by Bagaev et al.
Software package contains all original code used to process MxIF data.
Core provides imaging systems for advanced microscopy including confocal, multi-photon and super-resolution modalities, enabling users to address research questions in living systems across temporal and spatial scales. Staff offers training to use equipment, expertise about experimental strategy, design, image processing and analysis.
Electronics Core is electronics design, development and repair facility which specializes in proof-of-concept design and prototyping, and early stage development of medical devices and laboratory research instrumentation. Services include system design, schematic capture, printed circuit board layout, board fabrication, assembly and testing.
Core facility for synthetic biology experimentation including pilot-scale fermentation, high throughput automation, biological sample analysis, and cell-free protein synthesis.
Cancer research institute focused on the study of cancer formation and development.
Core specializes in high-throughput CRISPR screening using pooled or arrayed libraries in diverse cellular models. This technology assesses the effects of thousands of genetic perturbations at single-cell resolution with CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa). It also utilizes base and prime editing to investigate specific mutations, such as those relevant to cancer development and progression.
Core Facility provides technological platforms in the field of light microscopy. A team of highly qualified and experienced professionals supports IFOM's research activities, assisting in sample preparation and acquisition, data post-processing and image analysis.
Core Facility provides technology, instrumentation, and expert support for applications, including Immunophenotyping, Cell cycle and proliferation analysis, Metabolic studies, Apoptosis detection, Fluorescent protein expression analysis, Cytokine, chemokine, and intra/extracellular protein detection.
Specialized laboratory designed for growth, maintenance, and experimentation of living cells under controlled conditions. This facility is used in various fields such as biomedical research, drug development, and supports the culture of primary cells, immortalized cell lines, human-induced pluripotent stem cells (hiPSCs), and organoids, among others.
Core performs routine transmission and scanning Electron Microscopy and all kinds of immune Electron Microscopy, correlative light electron microscopy, three-dimensional EM (3DEM), quantitative stereological evaluation of data and more.
Core focuses on development of innovative biomedical technologies and devices for cancer research as well as biomedical applications using microfabrication and 3D printing.
Facility uses transmission electron microscopy coupled to low angle rotary shadowing to visualize nucleic acids. This technique allows the inspection of the fine ultrastructure of in vivo chromosomal DNA intermediates on properly enriched genomic DNA samples.
Core offers spatial omics processing on many different tissue types. Facility provides instrumnets including Bruker's GeoMx DSP ready for launch with anticipated launch of 10x Visium. Offers expert collaboration from project design to data handoff. Core has established workflows with additional shared resources on UNMC campus to allow for expertise throughout entire project.
Software tool for multi-level visualization of genomic statistical variables on rectangular chromosomes.
Web application provides users with visualization interface to explore and analyze interaction networks between miRNAs and target genes.
Rush University Medical Center is academic medical center for basic and clinical research, with physicians and scientists involved in hundreds of research projects developing and testing the effectiveness and safety of new therapies and medical devices. Offers residency and fellowship programs in medical and surgical specialties and subspecialties.