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Facility offers proteomics and metabolomics services.Provides training and instrumentation, such as the Orbitrap Q Exactive HF mass spectrometer from Thermo Fisher Scientific and advanced nano-LC systems.
Provides histology services from sample collection to data analysis.Training is available so that research staff understand the process. Contact us before you start your experiment so we can help you integrate histology with any other tissue-dependent assays you intend to perform.
Core facility provides tools for imaging, analysis, environmental testing, and micro/nanofabrication. Offers data, expertise, and hands-on training. From advanced materials to environmental systems, MCFF is the hub where discovery meets precision.
Software R tools for Blaser Lab Data Analysis. Package includes commonly used functions for R analysis in the Blaser Lab.
Platform is part of Research Computing and Services where researchers can perform compute-intensive tasks. It’s accessed through online user interface called Open OnDemand (via HPCNow!). The platform is run by Slurm, a job scheduler that manages and allocates resources, optimising resource use and power consumption. UC-RCH is housed in primary data centre on Dovedale, featuring 9 physical nodes and connecting to a virtual cluster with virtual machines and containers.
Core provides services for dissection of the immune response both phenotypically, functionally and transcriptionally at the single cell or population level. Technologies like single cell RNAseq (10x Genomics Chromium platform), multispectral fluorescent tissue imaging of FFPE tissues (Vectra 3 Imaging System, Akoya Biosciences), high-performance electrochemiluminescence plexing immunoassays (QuickPlex 120, MSD), and automated multiplexed single-cell and bulk protein analysis system (IsoLight, IsoPlexis) are available to investigators, providing immune cell (and beyond) characterization at the highest resolution. Other services also include project consultation, sample preparation, controlled rate freezing and cryopreservation/storage, as well as a comprehensive range of standardized and customizable immunological assays.
Metabolomics Core at Robert H. Lurie Comprehensive Cancer Center of Northwestern University provides LCMS based metabolomics services including identification, semi-quantification and quantification of metabolites and integrative genomics services related to metabolism.
Software R package to calculate the SHapley Additive exPlanations (SHAP) values in polynomial (instead of exponential) time. Supports models produced with xgboost, lightgbm, gbm, ranger, and randomForest packages.
Software python library for working with Google Sheets allowing users to open spreadsheet by title, key or URL. It also allows to read, write, and format cell ranges and more.
Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.
Software novel variational autoencoder framework for inferring integrated latent space representations for single cell transcriptomics data that uses a negative binomial generalized linear model for stronger batch correction, and code compilation for ten times faster training than existing tools. Enables superior analyses of multiple atlases, solving challenging integration tasks across sequencing platforms, development, and species, while simultaneously preserving desired biological signals.
Department of Medical Illustration’s Medical Sculpture Core advances education and research capabilities in medical sculpture. The space serves as an AU Core Research Lab to provide expertise in medical sculpture, volumetric visualization, and 3D printing. This lab space will offer educational and research opportunities for students to develop medical models such as surgical simulation models and patient education models. The research will improve surgical and medical training and provide insight into materials and technology to improve patient care.
Software tools for fitting Generalized Linear Models (GLMs) with time dependence (a.k.a. filters).
Spatial Collaborative Services combines expertise and technology from VAIs Genomics Core and Optical Imaging Core to offer investigators a seamless pipeline for spatial imaging. Services include consultation, histology preparation, sequencing and imaging based spatial platforms.
Provides mixed methods consulting services. Located in the Department of Family Medicine, team advises researchers at all levels in the health and social sciences who are developing proposals for funding, revising a manuscript, completing a research project or requiring Mixed Methods training.
Core for testing advanced air mobility (AAM), focusing on drones and electric aircraft, especially Beyond-Line-of-Sight (BVLOS) autonomous flight, to accelerate innovation and commercialization in the industry. It serves as a real-world "skyway" for researchers and companies to test new technologies like electric vertical takeoff and landing (eVTOL) aircraft, support Michigan Medicine's air transport, and foster aerospace startups, building on U-M's existing robotics and autonomous vehicle testing facilities.
Core for building and testing mobility innovation is part of the University of Michigan Transportation Research Institute. Helps advance safe and efficient transportation and mobility solutions. Makerspace for mobility and transportation innovators. Offers open-source tools, remote or on-site testing.
Code to conduct combinatorial barcoding. scRNA-seq-compatible tracer for identifying clonal relationships.
Software tool that harnesses natural genetic variation to determine the sample identity of each droplet containing a single cell (singlet) and detect droplets containing two cells (doublets). Genetic multiplexing of barcoded single cell RNA-seq.
Software Python package for single-cell chromosome contact data analysis. It includes the identification of cell types (clusters), loop calling in cell types, and domain and compartment calling in single cells. Facilitates visualization and comparison of single-cell 3D genomes.