Curator Dashboard

Software library for reading and writing SLOW5 files. Designed to facilitate use of data in SLOW5 format by third-party software packages. Used for efficient parallelization and acceleration of nanopore data analysis.

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• 7 months ago - submitted by Hasindu Gamaarachchi

File format for storing signal data from Oxford Nanopore Technologies sequencing devices. SLOW5 can be encoded in human-readable ASCII format, or more compact and efficient binary format (BLOW5) - this is analogous to the seminal SAM/BAM format for storing DNA sequence alignments.

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• 7 months ago - submitted by Hasindu Gamaarachchi

Software toolkit for converting, compressing, viewing, indexing and manipulating data in SLOW5 format. Used for handling nanopore data in SLOW5 format.

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• 8 months ago - submitted by Hasindu Gamaarachchi

Software R package implementing Gaussian Mixture Modelling for Model-Based Clustering, Classification, and Density Estimation.

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• 8 months ago - by Anonymous

Software R package for finite mixtures of regression models using EM algorithm. General framework for finite mixture models and latent class regression in R.

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• 8 months ago - by Anonymous

Software package for batch correction of heterogeneous RNA-seq datasets through latent sample matching.

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• 8 months ago - by Anonymous

Software package provides flexible, queriable R interface to graphs and walks of reference genomic intervals. gGnome is written in R6 object oriented standard and built around GenomicRanges, data.table, and igraph backend, and thus supports agile interaction with graphs consisting of hundreds of thousands of nodes and edges.

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• 8 months ago - by Anonymous

Core provides library prep and NGS services using Illumina NextSeq 2000. Our services include sample QC, DNA, RNA bulk sequencing, single cell sequencing, and Sanger sequencing.

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• 8 months ago - submitted by Edyta Vieth

Fully integrated system that combines concentrator, refrigerated cold trap, diaphragm pump and vacuum gauge in single, compact unit. Vacuum concentrator for drying DNA/RNA precipitates, PCR samples, proteins, enzyme, HPLC fractions in plates or tubes in water/ethanol or isopropanol and other organic solvents. SpeedVac SPD1030 System is designed for medium capacity (i.e.,120 x 1.5 mL tubes, other formats).

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• 8 months ago - submitted by Fabrizio Donnarumma

Branson Sonifier® ultrasonic cell disruptor / homogenizers are versatile laboratory units suitable for a broad range of liquid processing applications

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• 8 months ago - submitted by Fabrizio Donnarumma

Compact inverted research microscope configurable with wide variety of observation methods such as epi-fluorescence, phase contrast, DIC, and more. The Ts2R features camera port for digital imaging while maintaining compact body.

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• 8 months ago - by Anonymous

Facility provides customized solutions for complex single cell profiling with up to 45 markers simultaneously. Offers full service and established workflows from panel design, antibody labelling and sample processing to high-dimensional data analysis. Offers expertise in antibody conjugation, sample staining, and data analysis.

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• 8 months ago - by Anonymous

Core offers advanced services to detect, quantify, and characterize pathogens, as well as assess host immune responses. Supports both standardized and custom assay developments. MVSC is composed of three integrated units: Virology Unit which provides viral stocks for variety of viruses at BSL2 and BSL3, as well as assay services including virus expansion and characterization, viral titer by plaque and TCID50 assays, live virus neutralization and inhibition assays at both BSL-2 and –3. Viruses currently in use by the core include SIV, HIV, Zika, Dengue, SARS-CoV-2, Mayaro, Eastern Equine Encephalitis Virus, Poliovirus, Enterovirus D68, and others. Luminex and Serology Unit Services include antibody detection in serum or plasma by Luminex-based assays and/or ELISA for SPF-agents such as SIV, SRV, STLV, B virus, SFV, CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Trypanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. This unit also offers services for cytokine quantification in body fluids including serum and CSF, as well as tissue culture supernatant. Sequencing Unit provides services related to quantitative PCR and RT PCR detection of viruses such as SIV, Zika, and SARS-CoV-2, as well as next generation sequencing services including whole genome (pathogen or host), epigenetics, targeted amplicons, and 16S and ITS metagenomics. Sequencing unit also performs single cell RNA-seq (10x and Parse) assays as well as NGS based genotyping of NHP, including for major histocompatibility complex (MHC) allelic genotyping.

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• 8 months ago - by Anonymous

Light microscopy imaging core facility located in the Life Sciences Center at Dartmouth College (Hanover, NH). Facility personnel provide training and imaging guidance. Imaging instruments available to trained users include: laser scanning and spinning disk confocal systems (with super-resolution capability), a TIRF system, and a multiphoton microscope. Image analysis software (e.g. Nikon Elements, ZEN, Arivis Vision 4D, and Imaris Quant) is also available through the facility.

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• 8 months ago - submitted by Jessica Warren

Software R package to perform fixed and random-effects multivariate and univariate meta-analysis and meta-regression.

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• 8 months ago - by Anonymous

Software R package designed to streamline collection and use of cancer transcriptional signatures across bulk, single-cell, and spatial transcriptomics data. Used for collection and implementation of public transcriptional cancer signatures.

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• 8 months ago - by Anonymous

Software R package used in survival analysis that evaluates predictive accuracy of survival model. Measures how well model can distinguish between pairs of individuals with different survival times. Calculates proportion of all pairs of individuals whose predicted survival times are correctly ordered.

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• 8 months ago - by Anonymous

Software package for analysis of RNA expresison data. Used to make pythoneer bioinformatician workflow less colluded with R.

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• 8 months ago - by Anonymous

Software R package to quantify allelic imbalances associated with homologous recombination deficiency in ovarian cancer.

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• 8 months ago - by Anonymous

Software R package for analysis and visualization of macroevolutionary dynamics on phylogenetic trees.

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• 8 months ago - by Anonymous