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Creative Biogene provides global customers with ROS determination, using electron spin resonance (ESR), DCFH-DA fluorescent probe, NBT staining, DAB staining, and quantitative determination of hydrogen peroxide.

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• 4 years ago - submitted by Joe Cohen

Creative Biogene uses Seahorse XF real-time ATP rate measurement platform to efficiently and accurately detect mitochondrial aerobic respiration oxygen consumption rate (OCR) and glycolysis extracellular acidification rate (ECAR), and then convert into mitochondrial respiration ATP, glycolysis ATP, and total ATP production rate.

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• 4 years ago - submitted by Joe Cohen

The Creative Biogene's detection platform uses biochemical methods to efficiently and accurately detect the activities of mitochondrial respiratory chain complex and ATP enzyme. Results can help screen mitochondrial respiratory chain complex inhibitors quickly and effectively.

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• 4 years ago - submitted by Joe Cohen

Relying on rich experience, mature platform, and professional team, Creative Biogene provides efficient and accurate mitochondrial membrane potential detection services to help global customers' apoptosis research.

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• 4 years ago - submitted by Joe Cohen

Mitochondrial bioenergetics plays a key role in a variety of basic cellular processes, such as energy production, nucleotide biosynthesis, and metabolism. Not only the basic system of cell production and death (apoptosis), it is also necessary for embryonic development. Besides, mitochondrial bioenergetics is involved in the adaptive process and its gene products in species, as well as in the formation of animal reproductive disorders. Creative Biogene has built a comprehensive and perfect technical service platform for mitochondrial bioenergetics detection and analysis. Our experienced professional team uses mature and advanced technology to provide customers around the world with the most comprehensive mitochondrial bioenergetics research services.

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• 4 years ago - submitted by Joe Cohen

Most of the purposes for which amino acids are needed call for resolved samples of the chiral amino acids. There are major limitations of supply involved in the dependence on a natural source for uncommon amino acids, and asymmetric synthesis has yet to be developed into a reliable general process. In any case, synthesis followed by resolution is usually a more attractive proposition for the supply of novel or uncommon amino acids in required amounts since, even if the other methods are at first sight more convenient, these also require separation stages and checks of optical purity. Here, BOC Sciences provide chiral resolution of amino acids.

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• 4 years ago - submitted by Krystal Beily

Most of the purposes for which amino acids are needed call for resolved samples of the chiral amino acids. There are major limitations of supply involved in the dependence on a natural source for uncommon amino acids, and asymmetric synthesis has yet to be developed into a reliable general process. In any case, synthesis followed by resolution is usually a more attractive proposition for the supply of novel or uncommon amino acids in required amounts since, even if the other methods are at first sight more convenient, these also require separation stages and checks of optical purity. Here, BOC Sciences provide chiral resolution of amino acids.

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• 4 years ago - submitted by Krystal Beily

Asymmetric synthesis of amino acids is an important part of custom synthesis of amino acids. The methods mainly include resolution, high homologation of L-amino acids, asymmetric alkylation, asymmetric alkylation of imines, and asymmetric hydrogenation of dehydrogenated amino acids. Asymmetric amino acid synthesis methods are diverse and unique. Different synthesis methods can often complement each other. For example, asymmetric catalytic hydrogenation for the synthesis of chiral α-amino acids has high yield, high enantioselectivity, atomic economy, and environmental friendliness. Chiral adjuvant-induced alkylation methods can efficiently synthesize quaternary amino acids.

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• 4 years ago - submitted by Krystal Beily

Lab testing services, just as its name implies, including some routine chemical and physical analytical measures, are quick and convenient. Nowadays, state-of-the-art technologies and instrumentation along with close collaboration with synthetic organic chemists ensure the highest quality project execution. We solve the most difficult problems by asking the right questions and using the right tools.

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• 4 years ago - submitted by Krystal Beily

Lab testing services, just as its name implies, including some routine chemical and physical analytical measures, are quick and convenient. Nowadays, state-of-the-art technologies and instrumentation along with close collaboration with synthetic organic chemists ensure the highest quality project execution. We solve the most difficult problems by asking the right questions and using the right tools.

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• 4 years ago - submitted by Krystal Beily

X-ray crystallography-based characterization of samples currently has become the favoured method for both definitive sample identification and drug discovery process. A three-dimensional structure could be obtained by the technique which provides information in molecular identity, conformation, and packing. Structure-based drug design has proven to be effective in all aspects of drug discovery and development. It provides the chance to see the specific interactions of your compounds with the target you are working with. Based on the information viewed and analyzed, chemists may move forward with more confidence in optimizing their leads.

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• 4 years ago - submitted by Krystal Beily

Understanding the mechanism of cell death and survival is the key content of toxicological analysis and drug development and application. Since the cell death pathway is complex and dynamic, multi-parameter analysis is very important for the accurate detection of this process. BOC Sciences provides a variety of apoptosis detection services, involving early, mid and late detection of apoptosis.

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• 4 years ago - submitted by Krystal Beily

Time-resolved fluorescence resonance energy transfer (TR-FRET) is a technology that can be used for in vitro ubiquitylation testing. BOC Sciences has a mature TR-FRET technology platform, and also has a technical team with many years of experience in this technology. As a customer of BOC Sciences, you can discuss research goals and measurement parameters with our technical team. We will customize a suitable cooperation plan based on the discussion results, and provide you with detailed experimental data and analysis reports in a relatively short time.

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• 4 years ago - submitted by Marina Barrow

Ubiquitylation is an important protein post-translational modification process in PROTAC® technology and is the key to the degradation of the protein of interest (POI). BOC Sciences has established an advanced one-stop Proteolysis Targeting Chimeric (PROTAC) service platform to provide customers with ubiquitylation assay services, and enzyme-linked immunosorbent assay (ELISA) as a traditional technical means can quantify the ubiquitylation level of proteins. BOC Sciences has always been committed to providing high-quality research outsourcing services and has extensive experience in ELISA technology.

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• 4 years ago - submitted by Marina Barrow

The goal of Proteolysis Targeting Chimeric (PROTAC®) technology is to degrade the target protein, so in some related studies, the degradation ability of the target proteins needs to be measured. With many years of technical experience and a professional technical team, BOC Sciences has established an advanced one-stop PROTAC service platform to provide multiple technical services related to PROTAC technology, including degradation ability assay. Our rich experience and professional technical capabilities can help customers achieve degradation analysis of target proteins in a shorter period.

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• 4 years ago - submitted by Marina Barrow

Binding affinity measurement is an important test item related to proteolysis targeting chimera (Protac®) technology. As a professional technical service company in the field of drug discovery and research, BOC Sciences provides outsourcing services for binding affinity testing. Our technical team has many years of experience in binding affinity measurement to ensure the accuracy and repeatability of the test.

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• 4 years ago - submitted by Marina Barrow

Targeted protein degradation provides a broad prospect for drug discovery. In addition, they pose many challenges, not only the ability to find conjugates and suitable drug-like properties for PROTAC methods, but also the need to transcend chance to select E3 ligase as a template for drug discovery. Once the compound is designed and synthesized, it will follow a series of in vitro evaluation analyses from drug administration to intracellular target degradation to verify the effectiveness of Protacs in the drug development phase prior to clinical trials. BOC Sciences can provide a comprehensive set of in vitro evaluation analysis to monitor the specific parameters of each stage. As a leading service provider in the field of drug discovery and research, BOC Sciences is fully competent and dedicated to serving one-stop Proteolysis Targeting Chimeric (PROTAC®) based molecular drug discovery which has become a promising strategy in the area of drug discovery. With a comprehensive and advanced platform, we provides PROTAC In Vitro Evaluation service to customers around the world to meet new drug discovery goals.

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• 4 years ago - submitted by Marina Barrow

Private Ivy League research university in Philadelphia, Pennsylvania. University, established as College of Philadelphia in 1740, is one of the nine colonial colleges chartered before the U.S. Declaration of Independence.

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• 4 years ago - submitted by Edyta Vieth

A plugin to estimate chromosome sizes from karyotype images.BSD 3-Clause "New" or "Revised" License. A plugin to estimate chromosome sizes from karyotype images.

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• 4 years ago - submitted by Edyta Vieth

Mouse anti-CaMKIIα，Millipore，Cat#C265

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• 4 years ago - submitted by ronghao mu