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Software application for C-CAT CALICO database. Used for Germline-focUsed analysis of tUmoUr-detected variants with Nomogram for C-CAT CALICO database.
Software R package for conducting recalibration, conversion to hard probabilities, assessment of equivocal zones operations as well as calibration tools and conformal inference techniques for regression models.
Software R package for decision curve analysis. Used for evaluating and comparing prediction models that incorporates clinical consequences, requires only the data set on which the models are tested, and can be applied to models that have either continuous or dichotomous results.
Software gradient boosting (GBT, GBDT, GBRT, GBM or MART) framework based on decision tree algorithms, used for ranking, classification and other machine learning tasks.
Software cancer genome and RNA sequencing data analysis pipeline that detects genomic variants and transcriptomic changes.
Object-oriented software for model-robust covariance matrix estimators. Starting out from the basic robust Eicker-Huber-White sandwich covariance methods include: heteroscedasticity-consistent (HC) covariances for cross-section data; heteroscedasticity- and autocorrelation-consistent (HAC) covariances for time series data (such as Andrews' kernel HAC, Newey-West, and WEAVE estimators); clustered covariances (one-way and multi-way); panel and panel-corrected covariances; outer-product-of-gradients covariances; and (clustered) bootstrap covariances. All methods are applicable to (generalized) linear model objects fitted by lm() and glm() but can also be adapted to other classes through S3 methods.
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Portuguese national research infrastructure which provides expert consultation for the safe and effective use of vector technologies, and offers custom design and production services for multiple viral types to the national research community and other stakeholders.
Core for radioactive sample analysis and storage. Provides next generation in-vivo metabolism and biological assessment of new radiopharmaceuticals in clinical and preclinical studies. Houses analytical instruments dedicated for use with radioactive biospecimens.
Offers advanced instrumentation and expert support to advance understanding of brain function and brain disease by providing researchers with access to cutting-edge technologies. Provides access to advanced instrumentation for optical microscopy, genomics, metabolic imaging and other technologies, as well as image analysis software. Provides expert support and training, data quality and interpretation.
Web server for interactive and collaborative online docking to assist small compound molecular docking. In silico assessment of protein receptor interactions with small ligands.
Semi-manually curated database for biologically relevant ligand-protein binding interactions. Structure data are collected primarily from Protein Data Bank (PDB), with biological insights mined from literature and other specific databases. Database used for serving needs of ligand-protein docking, virtual ligand screening and protein function annotation.BioLiP2 offers significantly greater coverage of nucleic acid-protein interactions, and interactions involving large complexes, integrates structural alignment algorithms with structure prediction techniques, which enables composite protein structure and sequence-based searching.
Web application for protein-ligand binding site prediction. Starting from given structure of target proteins, COACH will generate complementray ligand binding site predictions using two comparative methods, TM-SITE and S-SITE, which recognize ligand-binding templates from the BioLiP protein function database by binding-specific substructure and sequence profile comparisons.
Web application for ligand binding site prediction. Used for prediction of ligand binding sites from protein structure.
Hub for clinical, genetic and functional datasets of preclinical cancer models.Provides details of cell model relationships, patient and clinical information, as well as access to associated genetic and functional datasets. Passports database contains curated details and standardized annotation for cell models, including cancer organoid cultures. Users can navigate database via tissue, cancer-type, genetic feature and data availability to select model. REST-API provides programmatic data access and exploration.
Software tool to read level DNA methylation analysis of bisulfite converted sequencing data.
Core provides high memory parallel processing environments and software in support of the university research, academic, and cybersecurity missions. HPC clusters use multiple computers to process data in parallel, greatly reducing the time to solution for most computational science tasks. They also provide storage to manage very large data sets.
Federally funded facility committed to advancing scientific research by delivering high-quality proteomic data. Provides proteomics analysis, technology, services, and rigorous quality standards.
Software tool to control Illumina HiSeq 2500 System. Open source Python code base and flow cell design that converts Illumina HiSeq 2500 instrument, comprising epifluorescence microscope with integrated fluidics, into open platform for programmable applications without need for specialized engineering or software development expertise.Enables non-specialists to develop and implement fluidics coupled imaging methods in benchtop system.
INECOL focuses on research on natural resources, conservation, and biodiversity, aiming to solve ecological problems and generate scientific knowledge.