Curator Dashboard

Software R package for analysing multiple omics datasets in the context of molecular pathways, biological processes and other types of gene sets.Method that first prioritises genes through multi-omics data fusion and then identifies enriched pathways with gene-level evidence from input datasets.

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• 2 months ago - submitted by Richard Culliford

Software tool to identify transposable element insertions from paired-end Illumina reads, barcode linked-reads, long reads (PacBio or Nanopore), or hybrid data from different sequencing platforms and takes whole-exome sequencing (WES) or whole-genome sequencing (WGS) data as input.

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• 2 months ago - submitted by Richard Culliford

Software tool to annotate high-impact five prime UTR variants either creating new upstream ORFs or disrupting existing upstream ORFs. Annotates variants in 5'untranslated regions (5'UTR) that create or disrupt upstream open reading frames.

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• 2 months ago - submitted by Richard Culliford

Software tool to detect linear enrichment of somatic mutations in user-defined regions of interest.

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• 2 months ago - submitted by Richard Culliford

Software application as PCAWG6 workflow to merge SVs from Sanger (BRASS), Broad Inst (DRanger and SnowMan ) and EMBL/DKFZ (DELLY).

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• 2 months ago - submitted by Richard Culliford

Software tool that estimates accumulated functional impact bias of somatic mutations in any genomic region of interest based on local simulation of the mutational process affecting it.

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• 2 months ago - submitted by Richard Culliford

Software application to detect significant clustering signals across genomic regions. Sequence-based clustering method to identify cancer drivers.

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• 2 months ago - submitted by Richard Culliford

Software tool designed to detect rare cancer driver genes from aggregated whole-exome sequencing data.

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• 2 months ago - submitted by Richard Culliford

Software tool for detecting microsatellite instability by next-generation sequencing.

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• 2 months ago - submitted by Richard Culliford

Software tool for automatic and comprehensive knowledge extraction based on mutational data from sequenced tumor samples from patients. Summarizes somatic mutations, genes and pathways involved in tumorigenesis.

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• 2 months ago - submitted by Richard Culliford

Software tool for detection and analysis of homologous recombination events.

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• 2 months ago - submitted by Richard Culliford

Software tool to detect somatic mutation hotspot regions in 3D protein structures.

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• 2 months ago - submitted by Richard Culliford

Software R package for analysis of mitochondrial DNA using sequencing data. Used for analyzing mtDNA single nucleotide variants and copy number variation. It has two components, mitoCaller and mitoCalc/fastMitoCalc.

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• 2 months ago - submitted by Richard Culliford

Software R package containing methods for sub-clonal reconstruction through SNVs and/or CNAs from whole genome or whole exome sequencing data.

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• 2 months ago - submitted by Richard Culliford

Software application to group genetic structural variant rearrangements into rearrangement clusters and footprints. Used in the PCAWG-6 project.

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• 2 months ago - submitted by Richard Culliford

Software R package for clustering and estimating cancer cell fractions (CCF) of somatic variants (SNVs/SVs) from bulk whole genome/exome data. Used for estimating cancer cell fractions .

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• 2 months ago - submitted by Richard Culliford

Core provides VisualSonics Vevo 3100 high-frequency ultrasound imaging unit, small animal imaging station, micro-injection system, anesthesia unit; Linear array transducers (MX250, MX550D, MX700); VevoLab use.

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• 2 months ago - by Anonymous

Software RNA-seq analysis pipeline that provides quantitative and locus-specific picture of Transposable Elements expression.

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• 2 months ago - by Anonymous

Web-based platform for interactive exploration of ribosome dynamics derived from 5′P mRNA degradome sequencing (5PSeq) data. Focused on changes in ribosome dynamics associated to mRNA decay that in some cases can be obscured in conventional ribosome profiling data.

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• 2 months ago - submitted by Irene Stevens

Metabolomics and Machine Learning Core provides metabolite profiling and stable-isotope tracing, molecular modeling, and machine learning to integrate datasets across transcriptomic, proteomic, and metabolomic analysis.

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• SciCrunch
• 2 months ago - submitted by Edyta Vieth