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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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  • Species:tetrahymena thermophila (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
H3.2∆3A
 
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RRID:TSC_SD02792 Tetrahymena thermophila HHT2 knockout, neo 2 cassette. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT2 (TTHERM_00189180) Macronucleus: Neo2 cassettes KO HHT2 SD02792 mpr1-1/mpr1-1 (hht2[∆::neo2]; pm-r, VII) TSC, Tetrahymena Stock Center TSC PMID:9343391
PMID:16908532
2026-02-14 07:55:04 0
HTA1-D19B1
 
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RRID:TSC_SD02393 Tetrahymena thermophila G4B1G10A x G4B3C1A. HTA.1 S1P plus all K changed to R in N-terminus used to rescue ∆HTA1∆HTA2 double knockout heterokaryon. Abolishes all acetylation. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500) Micronucleus: Neo 2 knockout of HTA1 and HTA2 genes Macronucleus: mutated HTA1 SD02393 hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (hta1[ S1V,K5R,K8R,K10R,k12R, K17R]; hta2[∆::neo2]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:12665578
PMID:11430834
2026-02-14 07:55:05 0
HTA1-D1A01
 
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RRID:TSC_SD02394 Tetrahymena thermophila G4B1G10A x G4B3C1A. wt HTA1 (pXL53) rescue ∆HTA1∆HTA2 double knockout heterokaryon. Assort to pm-s? Mates with HTA1-D1M01 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500) Micronucleus: Neo 2 knockout of HTAX and HTA1 genes Macronucleus: WT HTAX SD02394 hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (HTA1 (now HTAX) is WT but HTA2 (now HTA1) has neo2; pm-s?, ?) TSC, Tetrahymena Stock Center TSC PMID:11430834
PMID:12665578
2026-02-14 07:55:05 0
H3.3-Flag-1
 
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RRID:TSC_SD02314 Tetrahymena thermophila Somatic replace HHT3 gene with HHT3-Flag sequence. Neo2 in 5’ flanking of HHT3 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTT3 (TTHERM_00016170) Macronucleus: N-terminal His- tag of HHT3, not sure if complete replacement SD02314 mpr1-1/mpr1-1 (?HHT3/hht3[5’neo2,FLAGn]; pm-r, VII) TSC, Tetrahymena Stock Center TSC PMID:9343391
PMID:16908532
2026-02-14 07:55:05 0
CU2125
 
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RRID:TSC_SD00932 Tetrahymena thermophila SD00932 chx1-1/chx1-1; Nulli 2 (CHX1; pmr1-1; cy-s, pm-r, II) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:04 0
∆H4I, 2
 
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RRID:TSC_SD02322 Tetrahymena thermophila ∆H4I gl KO homozygous heterokaryon From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHF1 (TTHERM_00498190) Micronucleus: HHF1 ko with neo2 cassette SD02322 hhf1[∆::neo2]/ hhf1[∆::neo2] (mpr1-1; mp-r, ?) TSC, Tetrahymena Stock Center TSC PMID:15701804 2026-02-14 07:55:04 0
HTA1+HTB1-E1a
 
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RRID:TSC_SD02166 Tetrahymena thermophila HTX1/HTB1 double wt rescue; Rescue of h∆∆HTA∆∆HTB-FBD1F6 and FBB1D3 with Dryl's. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500), HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) Micronucleus: neo2 of HTAX, HTA1, HTB1, HTB2 Macronucleus: WT HTAX and HTB1, neo2 of HTA1, HTB2 SD02166 htax[∆::neo2]/htax[∆::neo2];hta1[∆::neo2]/hta1[∆::neo2] ; htb1[∆::neo2]/htb1[∆::neo2];htb2[∆::neo2]/htb2[∆::neo2] (HTAX/htax[∆neo2];hta1[∆::neo2]; HTB1/htb1[∆::neo2]; htb2[∆::neo2]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:19822522 2026-02-14 07:55:04 0
SB1839
 
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RRID:TSC_SD01992 Tetrahymena thermophila Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous. Submitted by Eduardo Orias, University of California, Santa Barbara SD01992 chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT3; cy-r, I) TSC, Tetrahymena Stock Center TSC PMID:10880474 2026-02-14 07:55:04 0
C2 VII
 
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RRID:TSC_SD01752 Tetrahymena thermophila Submitted by Joseph Frankel, University of Iowa SD01752 mat1-3/mat1-3; serH-4/serH-4 (mat 1-3; serH-4, VII) TSC, Tetrahymena Stock Center TSC PMID:6596476
PMID:17247884
PMID:3915784
PMID:11973302
2026-02-14 07:55:04 0
F2-A3 ∆CnjB
 
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RRID:TSC_SD02049 Tetrahymena thermophila Homozygous heterkaryon for ∆CnjB. Mates with ∆CnjB 2-1. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. cnjB (TTHERM_01091290) Micronucleus: CnjB part of coding replaced with neo3 SD02049 cnjB[∆?::neo3]/ cnjB[∆?::neo3] (cnjB/cnjB ; wt) TSC, Tetrahymena Stock Center TSC PMID:19596782 2026-02-14 07:55:04 0
B2KO-7
 
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RRID:TSC_SD01911 Tetrahymena thermophila Heterozygous germline transformant of BTU2 knockout. Derived from Cu428 X B2086 transformed w/ BHAB-2 (construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to B2KO-6. Created 12/29/97, in soybean until 4/98. B2KO-6 mates with B2KO-1,2,3,4,5,7,8. No others mated. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BTU2 (TTHERM_00836580) Micronucleus: H4-neo replaces BTU2 coding Macronucleus: H4-neo replaces BTU2 coding, not sure if complete SD01911 BTU2/btu2[∆,::H4-neo]; MPR1-1/mpr1-1 (BTU2/btu1[∆,::H4-neo]; MPR1-1/mpr1-1; mp-r, pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:10831613 2026-02-14 07:55:04 0
∆H3 major gl KO #19
 
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RRID:TSC_SD01881 Tetrahymena thermophila Germline homozygous heteokaryon for major H3 genes From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT1, HHT2, HHF1 (TTHERM_00570560, TTHERM_00189180) Micronucleus: Neo3 KO of HHT1, HHT2/HHF2 SD01881 hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (pm-s, mp-r, wt HHT, ?) TSC, Tetrahymena Stock Center TSC PMID:16908532
PMID:15701804
2026-02-14 07:55:04 0
GTU1/CU522 T146GHA #5
 
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RRID:TSC_SD01366 Tetrahymena thermophila pT146G HA somatic transformant in CU522, partial ? replacement of btu1(K350M) gene,GTU1 (T146G) with HA tag under control of MTT1 promoter. #1 and #5 are two separate single cell lines. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. GTU1 (TTHERM_00079520) Macronucleus: GTU1 with mutation T146G and c-terminal HA tag into the BTU1 locus under control of MTT1 promoter. Not sure if complete replacement. SD01366 btu1-1[K350M]/btu1-1[K350M] (btu1-1[K350M]/btu1-?[MTT1p,,∆,(::GTU1,T146G),HAc]; tax-r, ?) TSC, Tetrahymena Stock Center TSC PMID:12356864
PMID:16344310
2026-02-14 07:55:05 0
UCB402
 
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RRID:TSC_SD03300 Tetrahymena thermophila Mates with UCB401 From the Winey Lab at the University of Colorado Boulder. SFR10 (TTHERM_00392670) Micronucleus: cen2-1[∆::NEO2] SD03300 sfr10-1[∆::NEO2] (WT; WT, ?) TSC, Tetrahymena Stock Center TSC PMID:23426847 2026-02-14 07:55:05 0
A-C
 
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RRID:TSC_SD02219 Tetrahymena thermophila Somatic transformation of CU428 with HHO1 construct A-C From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHO1 (TTHERM_00823720) SD02219 mpr1-1/mpr1-1 (Circular permutation of HHO1 charge patch (see paper); pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:11972045 2026-02-14 07:55:04 0
UCB103
 
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RRID:TSC_SD03274 Tetrahymena thermophila Alanine scanning allele rescue of cen1∆ - Cen1 K29A, E30A, D33A. From the Winey Lab at the University of Colorado Boulder. CEN1 (TTHERM_00384910) Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-29 SD03274 cen1-1[∆::NEO2] (cen1-1[∆::NEO2]::cen1-29; Basal body disorganization (TS)., ?) TSC, Tetrahymena Stock Center TSC PMID:21562224 2026-02-14 07:55:04 0
CU2033
 
Resource Report
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RRID:TSC_SD00840 Tetrahymena thermophila SD00840 Nulli 2 (MPR1; mp-s, VII) TSC, Tetrahymena Stock Center TSC 2026-02-14 07:55:05 0
∆HTB2 gl 1.4
 
Resource Report
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RRID:TSC_SD02104 Tetrahymena thermophila This is the HTB2 germline KO homozygous heterokaryon. The 1.* series have different mating type from 10.* series. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) Micronucleus: Neo2 into HTB2 replacing coding Macronucleus: HTB2 coding replaced by neo2 but assorted to pm-s SD02104 htb2[∆::neo2]/htb2[∆::neo2] (mp-r, ?) TSC, Tetrahymena Stock Center TSC PMID:19822522 2026-02-14 07:55:04 0
S-H3.3+GFP/H3.3-79
 
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RRID:TSC_SD01779 Tetrahymena thermophila Somatic replace HHT3 gene with HHT3-GFP sequence. Neo2 in 5’ flanking of HHT3. Mac transformant,GFP tagged HHT3, green nuclei. From the Gorovsky lab, University of Rochester. HHT3 (TTHERM_00016170) Macronucleus: C-terminal GFP- tag of HHT3, not sure if complete replacement SD01779 mpr1-1/mpr1-1 (?HHT3/hht3[5’neo2,GFPc]; pm-r, VII) TSC, Tetrahymena Stock Center TSC PMID:16908532 2026-02-14 07:55:05 0
BMCG- ∆TWI11-5
 
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RRID:TSC_SD01811 Tetrahymena thermophila ∆TWI11 homokaryon transformed with Bsr-MTT1-CNA1-GFP. CNA1-GFP seq. was used to replace MTT1 coding seq. Bsr1 cassette was inserted at the 5’F seq. of MTT1 locus. The construct was transformed into mac. Thaw cells without drugs, then grow them in 60-100ug/ml blasticidin, Use 0.5-1 ug/ml cadmium chloride to express and see the green centromere. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. CNA1 (TTHERM_00146340), TWI11 (TTHERM_00144830) Micronucleus: TWI11 replaced by neo3 Macronucleus: CNA1 GFP tagged replaces MTT1 coding in MTT1 locus, bsr1 cassete in MTT1 5’ SD01811 twi11[∆?::neo3]/twi111[∆?::neo3] (twi11[∆?::neo3]/twi111[∆?::neo3]; MTT1/mtt1-?[5’ bsr1,∆,(::CNA1), GFPc]; bsr-r, pm-r, GFP tagged Cna1p, ?) TSC, Tetrahymena Stock Center TSC PMID:16738316 2026-02-14 07:55:05 0

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