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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00031262
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vhIs24.
Notes: vhIs24 [vha-6p::GFP::rab-5 Q78L + Cbr-unc-119(+)]. Large endosomes in the intestinal cells.
Proper citation: RRID:WB-STRAIN:WBStrain00031262 Copy
http://www.wormbase.org/db/get?name=WBStrain00031261
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; vhIs6.
Notes: vhIs6 [vha-6p::mCherry::tbc-2(R689K) + Cbr-unc-119(+)]. mCherry::TBC-2(R689K) is expressed in the intestine.
Proper citation: RRID:WB-STRAIN:WBStrain00031261 Copy
http://www.wormbase.org/db/get?name=WBStrain00031325
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; rrrIs1.
Notes: Made_by: Biedermann/Senften|"rrrIs1 [pie-1p::GFP::Histone H2B::cye-1 3'UTR + unc-119(+)]. Slightly Unc."
Proper citation: RRID:WB-STRAIN:WBStrain00031325 Copy
http://www.wormbase.org/db/get?name=WBStrain00031314
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001864(him-5)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001864(him-5), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; him-5(e1490) V; rdIs26.
Notes: Made_by: Ed Large|"Mutagen:Gamma radiation"|"rdIs26 [R08E3.4::GFP + unc-119(+)]. Construct contains ~5 kb upstream of R08E3.4A. Superficially wild-type. Reference: Large and Mathies (2010) Dev Biol 339(1):51-64."
Proper citation: RRID:WB-STRAIN:WBStrain00031314 Copy
http://www.wormbase.org/db/get?name=WBStrain00031313
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00001864(him-5)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001864(him-5), WBGene00006843(unc-119)
Availability: unknown
References:
Synonyms: unc-119(ed3) III; him-5(e1490) V; rdIs25.
Notes: Mutagen:Gamma radiation|"rdIs25 [pRA400; R08E3.4::GFP + unc-119(+)]. Superficially wild-type. Reference: Large and Mathies (2010) Dev Biol 339(1):51-64."
Proper citation: RRID:WB-STRAIN:WBStrain00031313 Copy
http://www.wormbase.org/db/get?name=WBStrain00031312
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; rdIs24.
Notes: Made_by: Ed Large|"rdIs24 [F12E12.5::GFP + unc-119(+)]. Spontaneous integrant of UL1189. Expresses GFP in somatic gonad during L2-L3 stages. Reference: Large EE, Mathies LD. Dev Biol. 2010 Mar 1;339(1):51-64."
Proper citation: RRID:WB-STRAIN:WBStrain00031312 Copy
http://www.wormbase.org/db/get?name=WBStrain00029202
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs5.
Notes: ltIs5 [(pIC36) pie-1p::kbp-1::GFP::TEV-STag + unc-119(+)].|"Mutagen:biolistic particle bombardment"
Proper citation: RRID:WB-STRAIN:WBStrain00029202 Copy
http://www.wormbase.org/db/get?name=WBStrain00029270
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: drSi41 II; unc-119(ed3) III.
Notes: drSi41 [hsf-1p::hsf-1::HA::unc-54 3'UTR + Cbr-unc-119(+)] II. hsf-1 cDNA containing an HA tag in frame between amino acids 370 and 371, under control of 4 kb of the hsf-1 promoter, integrated as a single copy by MosSCI on chromosome II at ttTi5605 in EG4322. Reference: Morton EA, Lamitina T. Aging Cell. 2012 Oct 26. doi: 10.1111/acel.12024.
Proper citation: RRID:WB-STRAIN:WBStrain00029270 Copy
http://www.wormbase.org/db/get?name=WBStrain00029218
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs37 IV; qaIs3507.
Notes: ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. qaIs3507 [pie-1::GFP::lem-2 + unc-119(+)].|"Supplementary_genotype GFP-LEM-2; mCherry-H2B; ltIs37 [pie-1p:mCherry:his-58 + unc-119(+)] IV. qaIs3507 [pie-1:GFP:lem-2 + unc-119(+)]"
Proper citation: RRID:WB-STRAIN:WBStrain00029218 Copy
http://www.wormbase.org/db/get?name=WBStrain00029219
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs37 IV; ltIs38.
Notes: ltIs37 [(pAA64) pie-1p::mCherry::his-58 + unc-119(+)] IV. ltIs38 [pAA1; pie-1::GFP::PH(PLC1delta1) + unc-119(+)]. Superficially wild-type. Maintain under normal conditions. Reference: McNally et al., JCB (2006).|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ltIs38 [pie-1p::GFP::PH(PLC1delta1) + unc-119(+)]. Superficially wild-type. Maintain under normal conditions. Reference: Essex A, et al. Mol Biol Cell. 2009 Feb;20(4):1252-67. doi: 10.1091/mbc.e08-10-1047. Epub 2008 Dec 24. PMID: 19109417"|"WBStrain mapped, WBPaper00059536 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061501 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061596 added based on AFP_Strain data."|"WBStrain provided so WBPaper00060223 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00062146 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00029219 Copy
http://www.wormbase.org/db/get?name=WBStrain00029215
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs44 V.
Notes: ltIs44 [pie-1p::mCherry::PH(PLC1delta1) + unc-119(+)].|"ltIs44pAA173; [pie-1p-mCherry::PH(PLC1delta1) + unc-119(+)]."|"Made_by: Audhya/Oegema"|"Supplementary_genotype"
Proper citation: RRID:WB-STRAIN:WBStrain00029215 Copy
http://www.wormbase.org/db/get?name=WBStrain00029216
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs38; ltIs24.
Notes: ltIs38 [pAA1; pie-1::GFP::PH(PLC1delta1) + unc-119(+)]. ltIs24 [pAZ132; pie-1::GFP::tba-2 + unc-119(+)].|"ltIs38 [pie-1p::GFP::PH(PLC1delta1) + unc-119(+)]. ltIs24 [pAZ132; pie-1::GFP::tba-2 + unc-119(+)]."
Proper citation: RRID:WB-STRAIN:WBStrain00029216 Copy
http://www.wormbase.org/db/get?name=WBStrain00029210
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00004027(pie-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004027(pie-1), WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs38.
Notes: ltIs38 [(pAA1) pie-1::GFP::PH(PLC1delta1) + unc-119(+)].|"ltIs38 [pie-1p::GFP::PH(PLC1delta1) + unc-119(+)]."|"Supplementary_genotype unc-119(ed3) III; ltIs38[pAA1; pie-1::GFP::PH(PLC1delta1) + unc-119(+)]"
Proper citation: RRID:WB-STRAIN:WBStrain00029210 Copy
http://www.wormbase.org/db/get?name=WBStrain00029207
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs22.
Notes: ltIs22[pPM3; pie-1::GFP-TEV-STag::KNL-2 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00029207 Copy
http://www.wormbase.org/db/get?name=WBStrain00029209
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs37 IV.
Notes: ltIs37 [(pAA64) pie-1p::mCherry::his-58 + unc-119(+)] IV. his-58 genomic sequence is inserted at Spe I site. Maintain under normal conditions. Reference: McNally et al., JCB (2006).|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. his-58 genomic sequence is inserted at Spe I site. Robust expression of transgene in early embryos and germ line; some expression in somatic cells also detectable. Maintain under normal conditions. Reference: McNally et al., JCB (2006)."|"WBStrain mapped, WBPaper00061161 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00029209 Copy
http://www.wormbase.org/db/get?name=WBStrain00029204
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs7.
Notes: ltIs7 [(pIC41) pie-1p::kbp-4::GFP::TEV-STag + unc-119(+)]. [NOTE: Array might be prone to silencing; rescue of unc-119 appears incomplete.]|"Mutagen:biolistic particle bombardment"
Proper citation: RRID:WB-STRAIN:WBStrain00029204 Copy
http://www.wormbase.org/db/get?name=WBStrain00029206
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: unc-119(ed3) III; ltIs14.
Notes: ltIs14 [(pASM05) pie-1p::GFP-TEV-STag::air-2 + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00029206 Copy
http://www.wormbase.org/db/get?name=WBStrain00029246
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)|WBGene00017641(csr-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00017641(csr-1)
Availability: available
References:
Synonyms: ltSi240 II; unc-119(ed3) III; csr-1(tm892) IV.
Notes: ltSi240 [csr-1p::csr-1(re-encoded) + Cbr-unc-119(+)] II. The csr-1 coding sequence in the transgene was re-encoded for RNAi-resistance (see Gerson-Gurwitz A, et al. Cell. 2016, Supplementary Figure S3A). [NOTE: it is not known if unc-119(ed3) is still present in the background of this strain.] Derived from strain OD1463; transgene rescues csr-1, so the balancer is not needed to maintain transgenic strain. Reference: Gerson-Gurwitz A, et al. Cell. 2016 Apr 7;165(2):396-409.
Proper citation: RRID:WB-STRAIN:WBStrain00029246 Copy
http://www.wormbase.org/db/get?name=WBStrain00029241
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: ltSi914 II; unc-119(ed3) III.
Notes: ltSi914 [osm-6p::vhhGFP4::zif-1::operon-linker::mCherry::his-11::tb b-2 3'UTR + Cbr-unc-119(+)] II. This transgenic strain mediates sensory neuron-specific degradation of GFP-tagged proteins; can be combined with endogenous locus GFP-tagging or rescue of a null mutant with a GFP fusion to examine sensory neuron-specific functions of target genes. Reference: Wang S, et al. URL: biorxiv.org/content/early/2017/01/30/104398|"ltSi914 [osm-6p::vhhGFP4::zif-1::operon-linker::mCherry::his-11::tbb-2 3'UTR + Cbr-unc-119(+)] II. This transgenic strain mediates sensory neuron-specific degradation of GFP-tagged proteins; can be combined with endogenous locus GFP-tagging or rescue of a null mutant with a GFP fusion to examine sensory neuron-specific functions of target genes. Reference: Wang S, et al. Development. 2017 Jun 15. pii: dev.150094. doi: 10.1242/dev.150094."
Proper citation: RRID:WB-STRAIN:WBStrain00029241 Copy
http://www.wormbase.org/db/get?name=WBStrain00029242
Source Database: WormBase (WB)
Genetic Background:
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
References:
Synonyms: ltSi915 II; unc-119(ed3) III.
Notes: ltSi915 [osm-6p::zif-1::operon-linker::mCherry::histone::tbb-2 3'UTR + Cbr-unc-119(+)] II. Control strain for OD2772, which mediates ciliated sensory neuron-specific degradation of GFP-tagged proteins. Superficially wild type. Reference: Wang S, et al. Development. 2017 Jun 15. pii: dev.150094. doi: 10.1242/dev.150094.
Proper citation: RRID:WB-STRAIN:WBStrain00029242 Copy
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