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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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htb1-K4Q-B4b Resource Report Resource Website |
RRID:TSC_SD02090 | Tetrahymena thermophila | ∆∆HTB knockout heterokaryons rescued by htb1-K4Q. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with K4Q | SD02090 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[K4Q] ; htb2 [∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2026-02-14 07:55:05 | 0 | ||||
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20452-1 Resource Report Resource Website |
RRID:TSC_SD03107 | Tetrahymena thermophila | Collected by Paul Doerder on 7/24/2009 from the pond designated Willard Pond in NH (latitude 43.02, longitude -72.02) Has a micronucleus. Mated with < 6 testers. | SD03107 | (?) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:06 | 0 | |||||||
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MTT-HA-PP50 #4 Resource Report Resource Website |
RRID:TSC_SD02819 | Tetrahymena thermophila | Used Xiayuan Song’s pXS 75 construct: neo 2 in 5 flank of MTT1 gene. 2 HA tags right after ATG. then PP50 coding sequence. PP50 is Ttherm. 00865300 into Ttherm 00865290 sequence. Need 100ug/ml pm in medium to keep the tagged gene present. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | PPO1 (TTHERM_00865290, TTHERM_00865300) | Macronucleus: PPO1 gene with 2 HA tags at n-terminus partially replace MTT1 coding, also neo2 in 5’ flanking region of MTT1. | SD02819 | mpr1-1/mpr1-1 (MTT1/mtt1-?[5’neo2, ∆, HAHAn(::PPO1)]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:22426537 | 2026-02-14 07:55:05 | 0 | ||||
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IA347 Resource Report Resource Website |
RRID:TSC_SD01571 | Tetrahymena thermophila | A complex combination of additivity, enhancement of the janus phenotype, and suppression of one aspect of the bcd phenotype (broadened oral domains). Described in detail in Cole et al. (1988). Submitted by Joseph Frankel, University of Iowa | JANB (janusB), BCD1 (broadened cortical domains1) | SD01571 | janB-1/janB-1; bcd1-1/bcd1-1 (janB-1; bcd1-1; janB, bcd1, II) | TSC, Tetrahymena Stock Center | TSC | PMID:28305473 | 2026-02-14 07:55:06 | 0 | |||||
|
HTA1-A2a Resource Report Resource Website |
RRID:TSC_SD02387 | Tetrahymena thermophila | New batch, rescue of h∆∆HTA-A1F14A1 and B1G6A These are KO of the major HTA genes HTAX and HTA1 in the mic with HTAX partial in the mac. Not mating type II,V1I or VII; same as HTA1-B1a. From the Gorovsky lab, University of Rochester. | HTA1 (TTHERM_00790790) | Micronucleus: KO of HTAX and HTA1 with neo2 Macronucleus: Complete KO of HTA1 with neo2, Partial replacement of HTAX with neo2 | SD02387 | htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2 (HTAX/htax[∆::neo2]; hta1[∆::neo2]; pm-r, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:06 | 0 | |||||
|
SB1817 Resource Report Resource Website |
RRID:TSC_SD01973 | Tetrahymena thermophila | Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous. Submitted by Eduardo Orias, University of California, Santa Barbara | SD01973 | chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT3; cy-r, I) | TSC, Tetrahymena Stock Center | TSC | PMID:10880474 | 2026-02-14 07:55:06 | 0 | ||||||
|
CU1040 Resource Report Resource Website |
RRID:TSC_SD00762 | Tetrahymena thermophila | Large deletion. May be missing entire left arm of chromosome 1. | SD00762 | chx1-1/chx1-1; pmr1-1/pmr1-1; Del 1L (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:05 | 0 | |||||||
|
cTTMG-HA #15 Resource Report Resource Website |
RRID:TSC_SD01342 | Tetrahymena thermophila | In mac at GTU locus, GTU coding region is replaced by neo cassette. At metallothionein locus, two alleles a) MTT coding region, b) GTU coding region with HA tag .Progeny of GTUKO5x6, transformed with pTTMGHA construct (GTU coding, HA tag driven by MTT promoter) to rescue GTU KO heterokaryon. Can mate with cTTMG-HA #12 or #14. Requires Cd to grow, use .25 to 1 ug/ml. GTU1-HA detected at protein level. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | GTU1 (TTHERM_00079520) | Micronucleus: GTU1 replaced by neo2 Macronucleus: GTU1with c-terminal HA tag into MTT1 locus, partial replacement | SD01342 | gtu1[∆::neo2]/gtu1[∆::neo2] (gtu1[∆::neo2]; MTT1/mtt1[∆::GTU1,HAc]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:12356864 PMID:16344310 |
2026-02-14 07:55:06 | 0 | ||||
|
HA-CNB (8) 2-6-6 Resource Report Resource Website |
RRID:TSC_SD02796 | Tetrahymena thermophila | Somatic HA-CnjB. HA sequence was inserted to just after the start codon. Neo3 was inserted upstream of CnjB. Background: Cu428. Grow in 0.5 to 1.0 ug/ml CdCl2 and 100 ug/ml paromomycin. From the Gorovsky lab, University of Rochester. | CnjB (TTHERM_01091290) | Macronucleus: Ha tagged CnjB with neo3 upstream | SD02796 | mpr1-1/mpr1-1 (cnjB[5’neo3,HAn]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:19596782 | 2026-02-14 07:55:07 | 0 | ||||
|
RNH1.3 HA-6 Resource Report Resource Website |
RRID:TSC_SD02711 | Tetrahymena thermophila | All Somatic RNH1.3 was replaced by RNH1.3 HA construct. Not sure where the neo3 is. CU428 background. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RNH13 (TTHERM_00283900) | Macronucleus: RNH1.3 with HA tag | SD02711 | mpr1-1/mpr1-1 (rnh1.3[HA]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:07 | 0 | |||||
|
∆HTAY(c2/3) heterokaryon 6-6, VI Resource Report Resource Website |
RRID:TSC_SD02679 | Tetrahymena thermophila | Knockout Heterokaryon of HTAY gene. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTAY (TTHERM_01079200) | Micronucleus: Neo3 ko of last 2/3 (AA123-388) of HTAY gene | SD02679 | htay[∆123-388::neo3]/htay[∆123-388::neo3] (VI) | TSC, Tetrahymena Stock Center | TSC | PMID:22426537 | 2026-02-14 07:55:06 | 0 | ||||
|
IA276 Resource Report Resource Website |
RRID:TSC_SD01226 | Tetrahymena thermophila | Submitted by Joseph Frankel, University of Iowa | CHX1 | SD01226 | chx1-1/chx1-1 (CHX1; cy-s, III) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:06 | 0 | ||||||
|
IA308 Resource Report Resource Website |
RRID:TSC_SD01229 | Tetrahymena thermophila | Formation of a fourth membranelle in the oral apparatus, with increased penetrance at higher temperature. Located on chromosome 3, probably 3L. The published phenotypic analysis was carrried out on a different homozygous clone that is now extinct. Submitted by Joseph Frankel, University of Iowa | MPC (membranellar pattern C) | SD01229 | mpC-1/mpC-1 (mpC-1, V) | TSC, Tetrahymena Stock Center | TSC | PMID:6491585 PMID:6491586 |
2026-02-14 07:55:07 | 0 | |||||
|
ATU-E443A,445-6A Resource Report Resource Website |
RRID:TSC_SD01902 | Tetrahymena thermophila | It is a progeny of conjugants of AAK02.7 X AAKO5.5 transformed with pATU-E443,445-6A derived from pTUB100E3-PvuII (linearized) where the ATU1 gene is marked with Hae III and Pvu II sites and E443A, E445A,E446A. From the Gorovsky lab, University of Rochester. | ATU1 (TTHERM_00558620) | Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E443A, E445A, E446A or neo replacing coding of some ATU1 genes | SD01902 | atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E443A, E445A,E446A ]; pm-r, mp-? , ?) | TSC, Tetrahymena Stock Center | TSC | PMID:9037049 PMID:10831613 |
2026-02-14 07:55:06 | 0 | ||||
|
IA310 Resource Report Resource Website |
RRID:TSC_SD01749 | Tetrahymena thermophila | Allelelic to cdaE-1 (IA137) and cdaE-3 (IA225). The extinct cdaE-4 IV sister clone showed identical phenotype, similarly high (possibly higher) expression at 39°C. compared to IA137 (Sister clone to IA312). Submitted by Joseph Frankel, University of Iowa | CDAE (cell-division-arrest E) | SD01749 | cdaE-4/cdaE-4 (cdaE-4; cdaE, III) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:07 | 0 | ||||||
|
B2KO-4 Resource Report Resource Website |
RRID:TSC_SD01908 | Tetrahymena thermophila | Heterozygous germline transformant of BTU2 knockout. Derived from Cu428 X B2086 transformed w/ BHAB-2 (construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to B2KO-6. Created 12/29/97, in soybean until 4/98. B2KO-6 mates with B2KO-1,2,3,4,5,7,8. No others mated. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BTU2 (TTHERM_00836580) | Micronucleus: H4-neo replaces BTU2 coding Macronucleus: H4-neo replaces BTU2 coding | SD01908 | BTU2/btu2[∆,::H4-neo]; MPR1-1/mpr1-1 (BTU2/btu1[∆,::H4-neo]; MPR1-1/mpr1-1; mp-r, pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 | 2026-02-14 07:55:07 | 0 | ||||
|
YN-HTAX (3) Resource Report Resource Website |
RRID:TSC_SD02201 | Tetrahymena thermophila | Shot Xiaoyuan Song’s i∆HTAY strain(partial replacement of HTAY with neo3) with construct MTT1-2HA tags after the ATG of HTAY n-terminus (AA1-258) followed by HTAX AA1-138) also has neo2 in 5’ flank of MTT1.Single cell line (3D) with most or all of HTAY replaced by the HA tagged YN-HTAX. Pushed to 30mg/ml pm resistance with Cd at 0.1-.0.5 ug/ml needed to express the YN-HTAX From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTAY (TTHERM_01079200) and HTA1 (TTHERM_00790790) | Macronucleus: Neo3 into HTAY, Chimeric YN-HTAX into MTT1 locus | SD02201 | mpr1-1/mpr1-1 (HTAY/htay[∆ ::neo3]; MTT1/mtt1[5’neo2, ∆ :: 2HAn,(HTAY1-258, HTAX1-138)]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:22426537 | 2026-02-14 07:55:06 | 0 | ||||
|
∆H3 gl 2.3 Resource Report Resource Website |
RRID:TSC_SD01872 | Tetrahymena thermophila | This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series All the 2.* series are separate cell lines. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170) | Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2 | SD01872 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; pm-s, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-02-14 07:55:06 | 0 | ||||
|
∆H3 gl 2.4 Resource Report Resource Website |
RRID:TSC_SD01871 | Tetrahymena thermophila | This is the germline KO homozygous heterokaryon. Both copies of major histone H3 were removed. Also HHF2 and intergenic region connecting it to HHT2. KO with Neo cassette. The ∆H3 gl 2.* series have a different mating type from the ∆H3 gl 10.* series From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170) | Micronucleus: Neo2 KO of HHT1 and HHT2/HHF2 | SD01871 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; pm-s, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2026-02-14 07:55:07 | 0 | ||||
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B2192 IVb Resource Report Resource Website |
RRID:TSC_SD01755 | Tetrahymena thermophila | A representative of the latest inbred generation of the B strain derived in the Frankel lab (by Leslie Jenkins). It was not used in any crosses with mutant clones. Submitted by Joseph Frankel, University of Iowa | SD01755 | mat1-2 (IV) | TSC, Tetrahymena Stock Center | TSC | 2026-02-14 07:55:06 | 0 |
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