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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13782163
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2018-08-24)
References:
Synonyms:
Notes: This model contains a knockin of the A53T-mutated SNCA gene deeming the rat SNCA gene non-functional. The knockin contains humanized amino acids for the region spanning amino acids 53-122. The resulting model expresses a humanized A53T alpha-synuclein protein without endogenous rat alpha-synuclein. Horizon Discovery
Proper citation: RRID:RGD_13782163 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904057
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-05-16)
References:
Synonyms:
Notes: This ZFN model contains biallelic 20 bp deletion within Abcba1 gene. Animals exhibit increased oral bioavailability of P-gp-specific substrates. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery
Proper citation: RRID:RGD_12904057 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800825
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-18)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 2 of rat Muc1 gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13800825 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904059
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-05-16)
References:
Synonyms:
Notes: This model carries knockout of Abcb1a and Abcb1b. Horizon Discovery
Proper citation: RRID:RGD_12904059 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207488
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Chrnb4 gene of LEW/NCrl rat embryos. The resulting mutation is a 4-bp deletion of exon 4 in the Chrnb4 gene. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13207488 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903272
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2017-05-10)
References:
Synonyms:
Notes: This model contains three knockout genes, the 20-bp deletion within rat Nr1i2, the ZFN-induced 10-bp deletion within rat Nr1i3 gene and the 760-bp deletion in the rat Ahr gene. Horizon Discovery
Proper citation: RRID:RGD_12903272 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800810
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-10-18)
References:
Synonyms:
Notes: CRISPR/Cas9 system and the single-stranded oligodeoxynucleotide (ssODN ) were combined to introduce the R231H mutation in the Kcnq1 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13800810 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792701
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2018-09-21)
References:
Synonyms:
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created. Homozygous knockout rats exhibit complete loss of Trpv1 protein. Horizon Discovery
Proper citation: RRID:RGD_13792701 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12902616
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-05-09)
References:
Synonyms:
Notes: These rats were created using CrISPR/Cas9 system to replace the Rat ApoE gene with the Human 4 allele APOE gene Horizon Discovery
Proper citation: RRID:RGD_12902616 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207513
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryorecovery (as of 2017-08-03)
References:
Synonyms:
Notes: This is compound transgenic/mutant rat strain derived from the breeding of SS-Tg(Slc12a1-Ncf2-2A-Luc) and SS-Ncf2em1Mcwi. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13207513 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207595
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of WKY/NCrl rat embryos. The resulting mutation is a 1-bp deletion in the exon 4 of the Tph1 gene. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13207595 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903270
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-05-10)
References:
Synonyms:
Notes: This model contains two knockout genes, the 20-bp deletion within rat Nr1i2 and the ZFN-induced 10-bp deletion within rat Nr1i3 gene. Horizon Discovery
Proper citation: RRID:RGD_12903270 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207514
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Live Animals (as of 2017-08-03)
References:
Synonyms:
Notes: CRISPR/SpCas9 was used to knock in the Epac-SH187, Epac-based FRET sensor into the Rosa26 locus under the control of the endogenous promoter using an Ad2 splice acceptor. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13207514 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792813
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-01)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SHRSP/A3NCrl rat embryos. The resulting mutation is a 11-bp deletion in Exon 3 of the Spp1 gene. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13792813 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13464329
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Embryo (as of 2023-09-28)
References:
Synonyms: , FPL
Notes: This spontaneous mutant strain wa found in a colony of Jcl:Wistar strain at the Institute of Environmental Toxicology in 1978: 3 rats out of 13 rats showed fused right pulmonary lobes with reduction deformity of middle pulmonary lobes. These rats also had the syndactylism or paten tof the eyelid. It was difficult to maintain this strain in homozygous condition, mating system has been changed to sib mating between heterozygous rats. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_13464329 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13208231
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2021-11-03)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of WKY/NCrl rat embryos. The resulting mutation is a 1-bp insertion in the exon 4 of the Tph1 gene. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13208231 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13799350
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-10)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13799350 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800877
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2026-01-14)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a net 10-bp insertion in exon 2 of rat C17h6orf52.
Proper citation: RRID:RGD_13800877 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13793378
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-03)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 9-bp deletion in exon 2. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13793378 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13793374
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: Cryopreserved Sperm (as of 2018-10-03)
References:
Synonyms:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of DA/MolTac rat embryos. The resulting mutation is a 1-bp deletion in exon 4. Contact MCW rat distribution at mcwcustomrats@mcw.edu
Proper citation: RRID:RGD_13793374 Copy
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