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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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ACI-Pvt1em2Shul/Rrrc Resource Report Resource Website |
RRID:RGD_150520211 | Rattus norvegicus | Using CRISPR/Cas9, a 568bp region of the Pvt1 gene was deleted from the ACI genome including all of exon 3. This strain is maintained at Rat Resource and Research Center. | 150520211 | mutant | Rat Genome Database (RGD) | RGD | Unknown (as of 2021-11-09) | 150520211 | 2026-02-14 03:50:09 | 0 | |||||
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ACI-Pvt1em3Shul Resource Report Resource Website |
RRID:RGD_150520212 | Rattus norvegicus | using CRISPR/Cas9, exon 8 of the pvt1 gene was deleted from the ACI genome. Resulting in a total excision of 588bp. | 150520212 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2021-11-05) | 150520212 | 2026-02-14 03:50:10 | 0 | |||||
|
ACI-Pvt1em3Shul/Rrrc Resource Report Resource Website |
RRID:RGD_150520213 | Rattus norvegicus | using CRISPR/Cas9, exon 8 of the pvt1 gene was deleted from the ACI genome. Resulting in a total excision of 588bp. This strain is maintained at Rat Resource and Research Center. | 150520213 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2021-11-05) | 150520213 | 2026-02-14 03:50:10 | 0 | |||||
|
ACI-Pvt1em4Shul Resource Report Resource Website |
RRID:RGD_150520214 | Rattus norvegicus | CRISPR/Cas9 was used to delete miR1208 in a 763bp excision in ACI rat embryos. | 150520214 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2021-11-05) | 150520214 | 2026-02-14 03:50:10 | 0 | |||||
|
SD-Cryba1Nuc1Dbsa Resource Report Resource Website |
RRID:RGD_126925756 | Rattus norvegicus | This spontaneous mutation was identified in the offspring of pregnant Sprague-Dawley rats purchased from Taconic Farms. This mutant exhibited abnormal eye phenotype including nuclear cataracts and was called Nuc1 rat. Sequencing of the mutant allele revealed a 27 base pair insertion in exon 6 of Cryba1. | 126925756 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 126925756 | 2026-02-14 03:50:09 | 0 | |||||
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SHR-Gja8m1+/-Cub Resource Report Resource Website |
RRID:RGD_150520205 | Rattus norvegicus | This strain is derived from SHR/OlaIpcv where a spontaneous mutation was observed in the NH2-terminal cytosolic domain of Cx50, L7Q. The connexin50 mutation in heterozygous state affects significantly the lipid profile and the oxidative stress parameters in SHR rats. | 150520205 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150520205 | 2026-02-14 03:50:09 | 0 | |||||
|
SD-Mir31em1Sage Resource Report Resource Website |
RRID:RGD_127285380 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce the gene knockout of Mir31 in the Sprague Dawley embryos. | 127285380 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 127285380 | 2026-02-14 03:50:09 | 0 | |||||
|
F344-ROSA26em1(AttP)Davis/Rrrc Resource Report Resource Website |
RRID:RGD_150520207 | Rattus norvegicus | The CRISPR/Cas9 system was used to introduce 2 AttP landing sites in the ROSA26 locus of F344/NHsd rat embryos. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center (RRRC) | 150520207 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-05) | 150520207 | 2026-02-14 03:50:09 | 0 | |||||
|
ACI-Pvt1em1Shul Resource Report Resource Website |
RRID:RGD_150520208 | Rattus norvegicus | Using CRISPR/Cas9, exon 1b of the Pvt1 gene was excised from the ACI/SegHsd genome in a 1165bp deletion. | 150520208 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2021-11-05) | 150520208 | 2026-02-14 03:50:09 | 0 | |||||
|
ACI-Pvt1em1Shul/Rrrc Resource Report Resource Website |
RRID:RGD_150520209 | Rattus norvegicus | The ACI-Pvt1em1Shul was created using CRISPR/Cas9 by Shull laboratory at UW madison. The exon 1b of the Pvt1 gene was excised from the ACI/SegHsd genome in a 1165bp deletion. This strain is now maintained at Rat Resource and Research Center. | 150520209 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150520209 | 2026-02-14 03:50:09 | 0 | |||||
|
LE-Nrxn1em1Mcwi Resource Report Resource Website |
RRID:RGD_25330089 | Rattus norvegicus | The rat strain was produced by injecting CRISPR/Cas9 targeting rat Nrxn1 into Crl:LE embryos. The result is a 4-bp deletion in exon 1. Autism Rat Model Resource. Contact MCW rat distribution at mcwcustomrats@mcw.edu | 25330089 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 25330089 | 2026-02-14 03:50:09 | 0 | |||||
|
SS-Kcnj2em4Mcwi Resource Report Resource Website |
RRID:RGD_14394496 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion mutation in exon 1 of the Kcnj2 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at mcwcustomrats@mcw.edu | 14394496 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 14394496 | 2026-02-14 03:50:09 | 0 | |||||
|
Wpk Resource Report Resource Website |
RRID:RGD_14995941 | Rattus norvegicus | The wpk mutation was first recognized in 1994 in a colony of outbred Wistar rats at Utrecht University (Utrecht, The Netherlands). In 1996, a breeding pair of test-proven heterozygotes were transferred to the University of Rotterdam (Rotterdam, The Netherlands), and a new subcolony was initiated. This colony has been maintained by brother-sister matings for more than five generations. Individuals heterozygous for the mutant allele were identified in each generation by test-crossing phenotypically normal offspring from known heterozygotes. A single C to T substitution in exon 12 was identified as the mutated allele in the Wpk rat. This mutation converts a proline to a leucine in the protein products(P394L). This mutation was not present in the parental Wistar strain. | 14995941 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 14995941 | 2026-02-14 03:50:10 | 0 | |||||
|
SD-Tspoem2Vpl Resource Report Resource Website |
RRID:RGD_150429830 | Rattus norvegicus | Tspo-targeted genome editing in Sprague Dawley rats embryos by microinjecting with optimized and customized ZFNs designed for targeted gene KO. Locus-specific PCR was performed to identify Rat7 founders using the following primer pairs: COMPOZr-1kbF: 50-CCTGGATATGCTGTGTCCCC-30 and COMPOZr-1kbR: 50-TGATGGGTCATTTGTGCCCT-30.; Normal PCRs generated 818 bp for WT and 652 bp for the mutant (166 bp deletion). | 150429830 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150429830 | 2026-02-14 03:50:10 | 0 | |||||
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SD-Ahrem2Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_13838845 | Rattus norvegicus | ZFN constructs were designed to target exon 2 which contains the DNA binding bHLH motif of the AHR gene.This ZFN model contains a 29-bp deletion in the rat Ahr gene. | 13838845 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13838845 | 2026-02-14 03:50:09 | 1 | |||||
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SD-Abcc8em1Cgen Resource Report Resource Website |
RRID:RGD_127285409 | Rattus norvegicus | TALEN system targeting the rat Abcc8 (sulfonylurea receptor 1, SUR1 ) gene was injected into Crl:CD(SD) embryos. This strain carries a 16-bp deletion corresponding to CCT CAC GGG GCT TCTG compared with wild-type rats is homozygous. No Abcc8 protein was detected in the liver and muscle tissues. Cyagen Biosciences Inc., Guangzhou, China | 127285409 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 127285409 | 2026-02-14 03:50:09 | 0 | |||||
|
DA-Csf1rtm(EGFP)+/-/Hume Resource Report Resource Website |
RRID:RGD_126779587 | Rattus norvegicus | Heterozygotes "SD-Csf1rtm(EGFP)+/-/Tset" were back-crossed for at least 7 generations to the inbred dark agouti (DA) background from the Animal Resource Centre, Western Australia. | 126779587 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 126779587 | 2026-02-14 03:50:09 | 0 | |||||
|
LEW-Myo15aci2/Ztm Resource Report Resource Website |
RRID:RGD_150404267 | Rattus norvegicus | LEW/Ztm-ci2 rat is an animal model for syndromal deafness that arose from a spontaneous mutation. Base substitution (T->C) in exon 56 of Myo15, leading to an amino acid exchange from leucine (Leu) to proline (Pro) within the carboxy-terminal MyTH4 domain in the proteins' tail region. | 150404267 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 150404267 | 2026-02-14 03:50:09 | 0 | |||||
|
SHR-Prdx2em1Izm Resource Report Resource Website |
RRID:RGD_38599208 | Rattus norvegicus | This strain is established at Kyoto University: By CRISPR/Cas9 system, mutation was introduced in Peroxiredoxin-2 (Prdx2) gene of SHR/Izm rat. This KO rat strain has 7-bp deletion (5'-CTCCGGC-3', c.6_13del7) in the exon2 of Prdx2 gene. Target sequence is 5?-CCTCCGGCAACGCGCACATCGGA-3?(PAM sequence:CCT). National BioResource Project for the Rat in Japan | 38599208 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2020-09-15) | 38599208 | 2026-02-14 03:50:09 | 0 | |||||
|
HHR/Hat Resource Report Resource Website |
RRID:RGD_38676459 | Rattus norvegicus | Hirosaki hairless rat (HHR) is a mutant strain spontaneously derived from Sprague-Dawley rats, and its inheritance is autosomal recessive. . These mutations are autosomal recessive and are suggested to be due to deletion of the keratin gene cluster. HHR attain sexualmaturity at approximately 10 weeks of age and give birth to young but are not able to nurse them. | 38676459 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 38676459 | 2026-02-14 03:50:09 | 0 |
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