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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://cran.r-project.org/src/contrib/Archive/aCGH.Spline/
An R package for array comparative genomic hybridization (aCGH) dye bias normalization.
Proper citation: aCGH.Spline (RRID:SCR_002927) Copy
https://github.com/GiBacci/StreamingTrim/
A DNA reads trimming software, written in Java, with which researchers are able to analyse the quality of DNA sequences in fastq files and to search for low-quality zones in a very conservative way.
Proper citation: StreamingTrim (RRID:SCR_002922) Copy
http://pfind.ict.ac.cn/software/pLabel/index.html
Mass spectral peak labeling software developed for proteomics research., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: pLabel (RRID:SCR_002923) Copy
https://github.com/itojal/hot_scan
A free software to detect genomic regions unusually rich in translocation breakpoints. More generally, it may be used to detect a region that is unusually rich in a given character of a binary sequence.
Proper citation: hot scan (RRID:SCR_002840) Copy
A fast and versatile Open Source docking software program that can be used to dock small molecules against proteins and nucleic acids.
Proper citation: rDock (RRID:SCR_002838) Copy
http://www.bioconductor.org/packages/release/bioc/html/Basic4Cseq.html
An R/Bioconductor package for basic filtering, analysis and subsequent near-cis visualization of 4C-seq data. Virtual fragment libraries can be created for any BSGenome package, and filter functions for both reads and fragments and basic quality controls are included. Fragment data in the vicinity of the experiment's viewpoint can be visualized as a coverage plot based on a running median approach and a multi-scale contact profile.
Proper citation: Basic4Cseq (RRID:SCR_002836) Copy
https://github.com/PacificBiosciences/SMRT-Analysis/
Open-source bioinformatics software suite for analyzing single molecule, real-time DNA sequencing data. Users can choose from a variety of analysis protocols that utilize PacBio and third-party tools. Analysis protocols include de novo genome assembly, cDNA mapping, DNA base-modification detection, and long-amplicon analysis to determine phased consensus sequences.
Proper citation: SMRT-Analysis (RRID:SCR_002942) Copy
http://www.bioconductor.org/packages/release/bioc/html/mzR.html
Software that provides a unified API to the common file formats and parsers available for mass spectrometry data. It comes with a wrapper for the ISB random access parser for mass spectrometry mzXML, mzData and mzML files.
Proper citation: mzR (RRID:SCR_002856) Copy
http://www.bioconductor.org/packages/release/bioc/html/BiGGR.html
Software package that provides an interface to simulate metabolic reconstruction from the BiGG database and other metabolic reconstruction databases. The package facilitates flux balance analysis (FBA) and the sampling of feasible flux distributions. Metabolic networks and estimated fluxes can be visualized with hypergraphs.
Proper citation: BiGGR (RRID:SCR_002854) Copy
http://www.bioconductor.org/packages/release/bioc/html/PAPi.html
An R package for predicting the activity of metabolic pathways based solely on a metabolomics data set containing a list of metabolites identified and their respective abundances in different biological samples. PAPi generates hypothesis that improves the final biological interpretation.
Proper citation: PAPi (RRID:SCR_002857) Copy
http://cran.r-project.org/web/packages/CNVassoc/
Software package that carries out association analysis of common copy number variants in population-based studies. It includes functions for analysing association under a series of study designs (case-control, cohort, etc), using several dependent variables (class status, censored data, counts) as response, adjusting for covariates and considering various inheritance models. It also includes functions for inferring copy number (CNV genotype calling). Various classes and methods for generic functions (print, summary, plot, anova, ... ) have been created to facilitate the analysis.
Proper citation: CNVassoc (RRID:SCR_002901) Copy
http://wanglab.pcbi.upenn.edu/coral/
A machine learning software package that can predict the precursor class of small RNAs present in a high-throughput RNA-sequencing dataset. In addition to classification, it also produces information about the features that are most important for discriminating different populations of small non-coding RNAs.
Proper citation: CoRAL - Classification of RNAs by Analysis of Length (RRID:SCR_010828) Copy
http://paed.hku.hk/uploadarea/yangwl/html/software.html
A toolkit for prioritizing SNVs and indels from next-generation sequencing data.
Proper citation: PriVar (RRID:SCR_010784) Copy
http://compbio.cs.toronto.edu/CNVer/
A method for CNV detection that supplements the depth-of-coverage with paired-end mapping information, where matepairs mapping discordantly to the reference serve to indicate the presence of variation.
Proper citation: CNVer (RRID:SCR_010820) Copy
http://sv.gersteinlab.org/cnvnator/
An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing.
Proper citation: CNVnator (RRID:SCR_010821) Copy
https://code.google.com/p/diplotyper/
A fully automated software tool which is available for Linux to investigate associations between a diplotype group and a phenotype in linear or logistic regression.
Proper citation: Diplotyper (RRID:SCR_010789) Copy
http://bioinfo-out.curie.fr/projects/freec/tutorial.html
Prediction of copy number alterations and loss of heterozygosity using deep-sequencing data.
Proper citation: Control-FREEC (RRID:SCR_010822) Copy
http://code.google.com/p/readdepth/
This package for R can detect copy number aberrations by measuring the depth of coverage obtained by massively parallel sequencing of the genome.
Proper citation: readDepth (RRID:SCR_010824) Copy
https://sites.google.com/site/vibansal/software/hapcut
A max-cut based algorithm for haplotype assembly using sequence reads from the two chromosomes of an individual.
Proper citation: HapCUT (RRID:SCR_010791) Copy
http://www.popgen.dk/software/index.php/Relate
Software providing a method that estimates the probability of sharing alleles identity by descent (IBD) across the genome and can also be used for mapping disease loci using distantly related individuals.
Proper citation: Relate (RRID:SCR_010794) Copy
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