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https://www.boisestate.edu/brc-cobre/matrix-biology/cores/biomedical-research-vivarium-core/

Core provides and supports gold standard of high quality mouse, rat and zebrafish care and services. All procedures are conducted according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals. The BRV is accredited at the highest standard of care through the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International.

Proper citation: Boise State University Biomedical Research Vivarium Core Facility (RRID:SCR_027621) Copy   

•   Source: SciCrunch Registry

https://www.ladydavis.ca/en/about/core-facilities/cell-imaging/

Core provides expertise in confocal, live cell, and fluorescent microscopy. Provides services in experimental design, instrumentation, training, technical assistance, and scientific guidance from sample preparation to data analysis and publication.

Proper citation: Lady Davis Institute Cell Imaging Core Facility (RRID:SCR_027624) Copy   

•   Source: SciCrunch Registry

https://pace.gatech.edu/

Core provides high performance computing (HPC) resources with technical support services, infrastructure, software, and more. PACE maintains several computing clusters for Georgia Tech’s faculty, students, and staff.

Proper citation: Georgia Institute of Technology Partnership for an Advanced Computing Environment Core Facility (RRID:SCR_027619) Copy   

•   Source: SciCrunch Registry

https://github.com/RWParsons/circacompare

Software R package for statistical analyses and comparison of two circadian rhythms. Used to estimate and statistically support differences in mesor, amplitude and phase, between circadian rhythms.

Proper citation: CircaCompare (RRID:SCR_027626) Copy   

•   Source: SciCrunch Registry

https://www.montana.edu/mbi/multiphoton_laboratory.html

Core provides multiphoton characterization of Genetically-Encoded Probes for the BRAIN Initiative researchers and broader neuroscience community. Services include Measuring of 2-photon absorption spectra in absolute, cross section values; Measuring 3-photon absorption spectra and cross sections; Characterizing multiphoton photobleaching parameters, i.e. quantum yields, nonlinear absorption cross sections:Measuring one-photon absorption, emission, and excitation spectra;Measuring fluorescence quantum yields and lifetimes;Evolving brighter two-photon probes.

Proper citation: Montana State University Biophotonics Core Facility (RRID:SCR_027627) Copy   

•   Source: SciCrunch Registry

http://biomed.brown.edu/rhode-island-biobank/

Cryogenic facility for human tissue and fluid samples under management of Brown University Division of Biology and Medicine and supports biomedical research on Brown campus and across affiliated hospitals of Warren Alpert Medical School.

Proper citation: Brown University Rhode Island Biobank Core Facility (RRID:SCR_004289) Copy   

•   Source: SciCrunch Registry

https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology

Supports Dartmouth Cancer Center investigators in design, performance, data analysis, and interpretation of pharmacology objectives in preclinical, clinical and epidemiological studies.

Proper citation: Dartmouth College Clinical Pharmacology Shared Resource Core Facility (RRID:SCR_000873) Copy   

•   Source: SciCrunch Registry

https://genome.med.harvard.edu/

Provided core services include Sanger DNA Sequencing, Next Generation DNA Sequencing (Four Illumina MiSeqs, four Illumina NextSeq 500s and one Illumina NovaSeq 6000),Next Generation Automated Library Sample Prep (Perkin Elmer Sciclone Genomic, ChIP, RNAseq and other methods), Single Cell DNA and RNA-Seq (10X Genomics Chromium), Bioanalyzer Analysis DNA and RNA (Two Agilent 2100 BioAnalyzers and two Agilent 2200 TapeStations), Qiagen Qiacube Automated DNA / RNA Prep (single to multiple samples), Oligonucleotide Ordering (IDT Portal), Reagents and Supplies Ordering (multiple vendors / products). Facility web based Laboratory Information Management System provides users with access to order services and supplies as well as retrieve data and review and pay invoices all online.

Proper citation: Harvard Medical School Biopolymers Core Facility (RRID:SCR_007175) Copy   

•   Source: SciCrunch Registry

https://bidmc.org/research/search/noninvasive-brain-stimulation

Provides education and training on the use of noninvasive brain stimulation for both clinical practice and research. Uses techniques like TMS and tDCS for diagnosing, treating, and researching neuropsychiatric conditions, aiding neurorehabilitation after brain injuries, and educating professionals, focusing on disorders like depression, schizophrenia, epilepsy, chronic pain, and stroke recovery to improve brain function and quality of life

Proper citation: BIDMC Berenson-Allen Center for Noninvasive Brain Stimulation Clinical and Research Core Facility (RRID:SCR_009659) Copy   

•   Source: SciCrunch Registry

http://mass-spec.stanford.edu

Core mass spec and proteomic services include open access lab for trained users with GC/MS, LC/MS, high resolution LC/MS, and MALDI-TOF instruments, help with intact protein analysis, targeted quantitation, drug discovery support, pathway analysis, protein interactions, FFPE tissue analysis, both labeled and label-free proteomics, and more. Please contact SUMS to discuss these and other custom projects including new application development.

Proper citation: Stanford University Vincent Coates Foundation Mass Spectrometry Laboratory Core Facility (RRID:SCR_017801) Copy   

•   Source: SciCrunch Registry

https://www.bif.northwestern.edu/

Shared use and training facility. Servies include Confocal Laser Scanning Microscopy, DIC (Differential Interference Contrast Microscopy), FCS (Fluorescence Correlation Spectroscopy), FLIP (Fluorescence-Loss-In-Photobleaching), FRAP (Fluorescence Recovery After Photobleaching),FRET (Fluorescence/ Forster Resonance Energy Transfer),Live-cell Imaging,Phase Contrast Microscopy,Widefield Fluorescence Microscopy,Image Processing and Analysis. Services include poster printing, and specimen preparation. Provides training for most instruments. Instruments include Leica DM6B Fluorescent Microscope (Hogan 5-112), Leica TCS SP8 Confocal Microscope (Hogan 5-128),Leica SP5 II Confocal Microscope (Hogan 5-114),Leica Spinning Disk Confocal Microscope (Hogan 5-113),DeltaVision Deconvolution Microscope (Hogan 5-111),Olympus IX83 Inverted Fluorescent Microscope (Silverman Hall 1-567),Olympus IX53 Inverted Color Microscope (Silverman Hall 1-567), LionHeart Automated Microscope BioTeck (Hogan 5-110).

Proper citation: Northwestern University Biological Imaging Core Facility (RRID:SCR_017767) Copy   

•   Source: SciCrunch Registry

http://nufab.northwestern.edu

Central micro/nano fabrication facility of Northwestern University. Provides range of nanofabrication equipment and technical expertise. Supports research in all areas of science, engineering, medicine, and interdisciplinary fields.

Proper citation: Northwestern University Micro/Nano Fabrication Core Facility (RRID:SCR_017779) Copy   

•   Source: SciCrunch Registry

https://sites.northwestern.edu/nucapt/

Facility specializes in high resolution chemical imaging by three dimensional atom probe tomography. APT produces three-dimensional (3D) atom-by-atom elementally and isotopically resolved image with sub-nanometer spatial resolution of sample volume typically 100 x 100 x 300 nm^3, by simultaneous high resolution direct-space imaging and atom-by-atom time of flight mass spectrometry. APT is particularly suited to study nano- or nanostructured materials.

Proper citation: Northwestern University Center for Atom Probe Tomography Core Facility (RRID:SCR_017770) Copy   

•   Source: SciCrunch Registry

https://geiselmed.dartmouth.edu/dartmouse/

Core dedicated to facilitation and development of congenic mice for pre clinical projects across United States. Provides genotyping, background checks to verify purity of mice DNA.

Proper citation: Darthmouth Geisel School of Medicine DartMouse Core Facility (RRID:SCR_017756) Copy   

•   Source: SciCrunch Registry

http://www.greatlakesgenomics.uwm.edu

Core provides services which include massively parallel sequencing on Illumina MiSeq, traditional Sanger sequencing, fragment analysis, quantitative PCR, nucleic acid extractions and QC, and digital PCR. Offers various level of service for Sanger sequencing and qPCR from full service to ready to load plates. Trains researchers in laboratory techniques and provide protocols. Each MiSeq sequencing project and qPCR project is unique and specifically designed so experimental design should be discussed before collecting samples.

Proper citation: Wisconsin University Great Lakes Genomics Center Core Facility (RRID:SCR_017838) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/csb/sbi

Core provides consultations and collaborations on research studies requiring computational structural biology methods. Analyses available are to study of static structures, molecular dynamics studies for analyzing contribution of dynamic and collective motions to macromolecular functionality. Trains researchers in computational structural biology techniques, or works in collaborative manner with researchers.Provides access to software tools for protein and DNA sequence analysis, protein fold determination, homology modeling, active site identification, and analysis of effects of various mutations on structure and function of protein, along with additional computational analyses.

Proper citation: North Carolina University at Chapel Hill R.L. Juliano Structural Bioinformatics Core Facility (RRID:SCR_017836) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/xray/contacts.html

Core provides equipment and resources for crystallographic analysis of target macromolecules and small inorganic or organic molecules. Performes crystallization, X-ray diffraction data collection (both in-house and synchrotron sources) processing, phasing, crystallographic refinement, model building, and visualization. Structural data provide information including biological functions, 3D-folding, ligand binding (small molecule or protein), or mutational effect of target macromolecules. Services include Crystallization Screening; Data Collection Service: Diffraction experiments will be performed at in-house X-ray facility as well as synchrotron beam lines; Structure Determination and Analysis: complete data set collected at home or synchrotron will be processed for inorganic, organic, protein or nucleic acid structure determination, model building and crystallographic refinement. Other Structural Biology Related Services: core facility offers thorough analysis of macromolecular structure for publication or grant applications, also provides computational experiments such as homology modeling and in silico ligand docking.

Proper citation: Scripps Research Institute - Florida X ray Crystallography Core Facility (RRID:SCR_017835) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/csb/nmr/

Core to support academic and industrial users. Spectrometer time is available to trained users for an hourly fee. Lab manager trains new users, consults to determine whether NMR will be useful in their research, and helps design experimental plan to obtain information they need. Manager also operates spectrometer for users whose experiments do not justify time and expense of individual training.

Proper citation: North Carolina University at Chapel Hill School of Medicine Biomolecular NMR Laboratory Core Facility (RRID:SCR_017841) Copy   

•   Source: SciCrunch Registry

http://www.nationwidechildrens.org/genomics

Core performs and analyzes integrated clinical genomic, molecular, microarray, FISH, and cytogenetic analyses to diagnose broad range of inherited diseases and cancer. Serves as centralized clinical testing laboratory for Children Oncology Group leukemia, Wilms tumor, medulloblastoma, and rhabdomyosarcoma studies. Emphasizes collaborative interactions between clinicians, physician-scientists, and basic science investigators to quickly transition cutting edge research results into cutting edge diagnostics, using technology platforms. Services include Whole Exome Sequencing (WES),cytogenetic chromosome analysis,Fluorescence in situ Hybridization,Chromosomal microarray analysis,Molecular Genetic Testing - Inherited Diseases,Molecular Genetic Testing - Cancer.

Proper citation: Steve and Cindy Rasmussen Institute for Genomic Medicine Clinical Laboratory Core Facility at Nationwide Children�s Hospital (RRID:SCR_017840) Copy   

•   Source: SciCrunch Registry

http://iubemcenter.indiana.edu

Core provides access to electron microscopy equipment and services which includes AFS 2 Freeze Substitution robot,Denton DV502 Carbon Evaporator,JEOL JEM 1010,JEOL JEM 1400plus,JEOL JEM 3200FS,Polaron E5100 sputter coater,Vitrobot Mk3,Wohlwend High Pressure Freezer. Users have to be included on user e-mail lists and have iLab account in order to use core.

Proper citation: Indiana University - Bloomington Electron Microscopy Center Core Facility (RRID:SCR_017845) Copy   

•   Source: SciCrunch Registry