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https://www.colorado.edu/lmcf/
Provides access to instruments and training. Instruments including Dell Precision 7910 Analysis PC,Leica DMRXA Upright Widefield Microscope, Nikon E600 Upright Widefield Microscope, Nikon N-SIM structured illumination super-resolution and A1 laser scanning confocal microscope, Nikon Inverted Spinning Disk Confocal Microscope, Zeiss 510 Laser Scanning Confocal Microscope.
Proper citation: Colorado University at Boulder Light Microscopy Core Facility (RRID:SCR_018993) Copy
Core helps researchers investigate interactions between small molecules and biological systems by providing medicinal chemistry and chemical biology expertise and organic synthesis support.
Proper citation: Oregon Health and Science University Medicinal Chemistry Core Facility (RRID:SCR_019048) Copy
https://www.danforthcenter.org/our-work/core-facilities/phenotyping/
Core provides instruments including Scanalyzer 3D platform which consists of multiple digital imaging chambers connected to controlled environment Conviron growth house by conveyor belt system, resulting in continuous imaging loop and enables repeatedly image plants at multiple points throughout time.RGB imaging allows visualization and quantification of plant color and structural morphology. Near-infrared (NIR) enables visualization and quantification of plant water-use efficiency.Watering and weighing stations are customizable to deliver water and nutrients on specified schedule by volume or weight. Standard phenotyping services include operation and maintenance of LemnaTec Scanalyzer system, as well as technical support and troubleshooting.
Proper citation: Donald Danforth Plant Science Center Phenotyping Core Facility (RRID:SCR_019049) Copy
http://www.dartmouth.edu/~dartlab/
Offers services in customized end point assays using human WB/PBMCs for clinical trials, ELISPOT, multiplex cytokine analysis, cell energy analysis, blood processing and cryopreservation,up to 20 color flow cytometry phenotyping and up to 11color FACS cell subset sorting. Provides consultation, data analysis, and Flow Cytometry training course.
Proper citation: Dartmouth Geisel School of Medicine Immunoassay and Flow Cytometry Core Facility (RRID:SCR_019165) Copy
https://www.colorado.edu/sharedinstrumentation/core-facilities/intermountain-neuroimaging-consortium
Magnetic resonance imaging research facility. Provides Tesla Siemens MAGNETOM Prismafit MRI scanner, located at Center for Innovation and Creativity (CINC) on CU Boulder campus.
Proper citation: Colorado University at Boulder Intermountain Neuroimaging Consortium Core Facility (RRID:SCR_018990) Copy
https://umassmed.edu/research/cores/mediaprep/
Provides custom made microbiological media for bacteria,yeast,C.elegans,Chlamydamonas research in liquid and agar forms. Common lab buffers and solutions are also available.
Proper citation: UMass Medical School Media Prep Core Facility (RRID:SCR_019167) Copy
https://www.colorado.edu/lab/massspec/
Offers analytical and instructional expertise in mass spectrometry with practical training and access to instrumentation.Located in room C1B90 of Jennie Smoly Caruthers Biotechnology Building houses six mass spectrometry systems.Instruments are interfaced with chromatographic system in order to separate complex mixture samples. Offers training for open access to some instruments including Thermo ISO LT GCMS, Synapt G2 HDMS, Agilent 6120 LCMS, and 4000 Q-trap QQQ instruments.
Proper citation: Colorado University at Boulder Central Analytical Mass Spectrometry Core Facility (RRID:SCR_018992) Copy
https://brcf.medicine.umich.edu/cores/bioinformatics-core/
Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.
Proper citation: University of Michigan Medical School Bioinformatics Core (RRID:SCR_019168) Copy
https://www.med.unc.edu/flowcytometry/
Core provides flow cytometry services to UNCCH research community as well as to others in Research Triangle Park area.Provides help with experimental design, sample acquisition, data analysis, and sorting, training to run analyzers independently at reduced cost, guidance about rigor and reproducibility in all aspects of experimental design, data acquisition, analysis and reporting.
Proper citation: University of North Carolina at Chapel Hill Flow Cytometry Core Facility (RRID:SCR_019170) Copy
https://transgenic.uchicago.edu
Provides investigators with genetically manipulated mice through transgenic technology or embryonic stem cell manipulation. Provides fully operational construction and gene targeting service. Offers annual course in Mouse Handling and Breeding. Provides transgenic plasmid and BAC, CRISPR and TARGATT injections, ES Cell targeting, screening, culture and blastocyst injections, rederivation, breeding and mouse services and consultation on project development.
Proper citation: University of Chicago Transgenic and ES Cell Technology Mouse Core Facility (RRID:SCR_019171) Copy
https://dentistry.musc.edu/research/gcohr
Core offers investigators opportunity to address research questions that require use of gnotobiotic animals. Standard services provide germ free mice (e.g. BALB/c, C57BL/6), deriving new strains of mice into germ free state by caesarean section, tissue collection and/or fluid from mice that have not received treatment or manipulations, exporting germ free mice in sterile transporters to other institutions. Non-Standard Services include maintaining and breeding newly derived germ free mice, administration of specialized diets, administration of compounds as therapeutic or disease-inducing agents, tissue collection and/or fluid from mice that have received treatment or manipulations.
Proper citation: Medical University of South Carolina College of Dental Medicine Gnotobiotic Animal Core Facility (RRID:SCR_018884) Copy
https://www.unh.edu/research/welcome-university-instrumentation-center
University wide core facility offers NMR,SEM including FIB, EBS, EBSD, Tensile Stage,Confocal,X-Ray Photoelectron Spectroscopy,X-Ray Microscope aka Micro CT, Expert analysis of research and industrial samples,Training in scientific instrument operation and data analysis, Maintenance, repair, and calibration of instruments,Specialty instrument engineering design and application services,Facilitation of access to scientific instruments throughout the university.
Proper citation: University of New Hampshire University Instrumentation Center Core Facility (RRID:SCR_021101) Copy
https://www.lsi.umich.edu/science/centers-technologies/center-structural-biology
Comprehensive structural biology resource.Provides high throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, and X-ray facility with access to high energy synchrotron radiation. Provides expert guidance to researchers through every stage of project, collaborating and consulting with researchers who use the facilities. Service categories are Chemical, Material and Protein Characterization, Molecular Biology. Services include Cloning, Crystallization, Differential thermal analysis, Drug development, NMR (small molecule), PCR, Protein crystallography, Protein engineering, Protein production, Structure determination, Xray.
Proper citation: University of Michigan Center for Structural Biology Core Facility (RRID:SCR_021065) Copy
Core research facility housed in Department of Geological Sciences for fast, non-destructive characterization and chemical imaging of diverse materials spanning minerals (thin sections and powders), biological samples, fluids, dissolved gases, and much more.
Proper citation: University of Colorado Boulder Raman Microspectroscopy Lab Core Facility (RRID:SCR_019305) Copy
https://instaar.colorado.edu/research/labs-groups/organic-geochemistry-laboratory/
Shared analytical facility for multidisciplinary and collaborative research in fields as diverse as biogeochemistry, geobiology, astrobiology, environmental microbiology, paleoceanography, paleoclimatology, and energy, among others.Focuses on extraction, purification, separation, and chemical and isotopic characterization of organic molecules extracted from environmental and culture samples.
Proper citation: University of Colorado Boulder Organic Geochemistry Laboratory Core Facility (RRID:SCR_019301) Copy
https://www.colorado.edu/lab/biocore/
Purpose is to connect MCDB, EBIO, and IPHY researchers to campus research resources.
Proper citation: University of Colorado Boulder BioCore Core Facility (RRID:SCR_019302) Copy
Fully equipped (U-Th)/He thermochronology facility.
Proper citation: University of Colorado Boulder CU Thermochronology Research and Instrumentation Lab Core Facility (RRID:SCR_019303) Copy
Designed to measure relative abundance of stable isotopes of light elements and molecules.
Proper citation: University of Colorado Boulder Earth Systems Stable Isotope Lab Core Facility (RRID:SCR_019300) Copy
https://cami.northwestern.edu/
Provides access to range of preclinical imaging modalities and support services. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture. Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis. Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.
Proper citation: Northwestern University Center for Advanced Molecular Imaging Core Facility (RRID:SCR_021192) Copy
https://research.med.psu.edu/core-facilities/zebrafish/
Provides Penn State research community with modern, centralized facility for housing, breeding and performing experiments with zebrafish.Provides physical and intellectual infrastructure for investigators whose research can benefit from use of zebrafish as model system.
Proper citation: Penn State Hershey College of Medicine Zebrafish Functional Genomics Core Facility (RRID:SCR_021199) Copy
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