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https://www.urmc.rochester.edu/rochester-human-immunology-center.aspx

Designed to enhance multi-disciplinary research initiatives catalyzing key clinical and basic immunology research in vaccines, HIV/AIDS, autoimmunity, allergy/asthma, transplantation as well as cancer immunology.Provides expertise in multichromatic flow cytometry (immunophenotyping, antigen-specific intracellular cytokine staining and cell sorting), T and B cell Elispot, Fluorispot, T regulatory cell assays, magnetic bead selection of cell populations, and Luminex multiplexed bead array assays.Provides specialized clinical specimen analysis services for clinical studies or contracts.

Proper citation: Rochester University Human Immunology Center Core Facility (RRID:SCR_018670) Copy   

•   Source: SciCrunch Registry

http://www.biotech.ufl.edu/bioinformatics/

Core offers bioinformatics consulting and data analysis services to help researchers analyze and understand large data sets acquired from next generation sequencing and array based technologies.Bioinformatics staff members have extensive experience in bioinformatics, genomics, transcriptomics and translational informatics in plant, animal and microbial systems. Expertise includes big data analysis, statistical analysis, software development and high performance computing.

Proper citation: University of Florida ICBR Bioinformatics Core Facility (RRID:SCR_019120) Copy   

•   Source: SciCrunch Registry

https://www.claflin.edu//academics-research/schools-departments/school-of-natural-sciences-and-mathematics/facilities

Core facility is equipped with instrumentation to support proteomic and metabolomic research, as well as equipment for materials characterization. Key instruments include a Bruker 700MHz NMR, two Bruker XRDs (Powder and Crystal), and Bruker Micro ToF mass spectrometer.

Proper citation: Claflin University Molecular Science Research Center Core Facility (RRID:SCR_018836) Copy   

•   Source: SciCrunch Registry

http://tools.thermofisher.com/content/sfs/manuals/cms_041850.pdf

Automated peptide synthesizer for chain assembly steps in solid phase peptide synthesis or FastMoc chemistry. Data is based on conductance or ultraviolet UV absorbance of reagent, solutions, and solvents in the synthesis cycle.

Proper citation: Applied Biosystems 433A Peptide Sequencer (RRID:SCR_018440) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/neuroscience/core-facilities/neuro-microscopy/

Microscopy Core for high resolution imaging and aims to make this technology accessible to neuroscientists and other scientific researchers.Provides advanced systems for cellular and molecular imaging of in vitro and in vivo samples, implements new imaging technologies, particularly related to real time and tissue clearing based imaging of neurodevelopment and neural functions, offers training, consultation, data analysis, image processing, and centralized technical expertise.

Proper citation: University of North Carolina at Chapel Hill School of Medicine Neuroscience Microscopy Core Facility (RRID:SCR_019060) Copy   

•   Source: SciCrunch Registry

http://cores.musc.edu/Core/MS

Core provides expertise, services, education, and instrumentation to enhance biomedical research through LC-MS/MS-based proteomics. Services are offered for protein identification; characterization of post-translational modifications; and quantitative proteomics to identify differentially expressed/degraded proteins, regulated sites of post-translational modification, protein-protein interactions, and protein targets of drugs identified in phenotypic screens. Analyses include sample preparation, LC-MS/MS, database searching, generation of reports, and assistance with data interpretation. Faculty and staff assist with experimental design and development/optimization of customized methodology for analysis of post-translationally modified peptides (e.g. phosphorylation and O-GlcNAc modification, N- and O-linked glycosylation, Cys modifications including S-glutathionylation, and glycation of Lys and Arg). Quantitative approaches including metabolic labeling (SILAC), isobaric tagging (iTRAQ/TMT), and label free proteomics (LFQ) are performed on Orbitrap Elite or Orbitrap Fusion Lumos Mass Spectrometers. Developes methodology to identify alterations in post-translational modifications that impact signal transduction, transcription, translation, and response to therapeutics with goal of enabling investigators to discover molecular mechanisms underlying disease progression and therapeutic response.

Proper citation: South Carolina Medical University Mass Spectrometry Core Facility (RRID:SCR_017959) Copy   

•   Source: SciCrunch Registry

https://devsci.northwestern.edu/neurodevelopmental-resource-core-services/

Core provides services in support of research, education, and assessment technology related to neurodevelopmental research methods. Services include Scientific Consultation, Workshops and Training,EEG/ERP,Eye-tracking,Clinical and Behavioral Measure Services.Services include Data Collection, Use of Equipment, Experimental Task Creation and Preparation.

Proper citation: Northwestern University DevSci Neurodevelopmental Core Facility (RRID:SCR_017957) Copy   

•   Source: SciCrunch Registry

https://fralinlifesci.vt.edu/core-services/mass-spectrometry-incubator.html

Facility supports Virginia Tech's research infrastructure as mass spectrometry analysis and education center. Provides training in sample preparation, instrument operation and data analysis, with strong emphasis on metadata and analytical requirements for publication of metabolomic and proteomic results.

Proper citation: Virginia Tech Mass Spectrometry Incubator Core Facility (RRID:SCR_017956) Copy   

•   Source: SciCrunch Registry

http://www.umass.edu/ials/mass-spectrometry

Core offers instrumentation for characterizing elements and compounds across the entire mass range. Specialized mass spectrometers encompass variety of ionization techniques and separation devices to cover wide range of analytical capabilities.Facility accepts samples and will perform requested analysis.Offers training to conduct experimentation. Instruments include Bruker SolariX FT-ICR,Bruker MicroTOF II ESI,Bruker MicroFLEX MALDI,JEOL MStation sector with EI and FAB sources.

Proper citation: UMass Amherst Mass Spectrometry Core Facility (RRID:SCR_019063) Copy   

•   Source: SciCrunch Registry

https://www.themiamiproject.org/research-resources/core-facilities/viral-vector-core/

Produces high titer lentiviral and AAV viral particles. Stock viruses including GFP-, mCherry-, and LacZ-expressing lentiviral and AAV particles can be purchased. For generating custom viral particles, investigator provides high quality maxiprep of transfer plasmid to be packaged into viral particle of choice. Turn around time is about 2 weeks for lentivirus and AAV viral particles.

Proper citation: Miami University Miller School of Medicine Viral Vector Core Facility (RRID:SCR_018303) Copy   

•   Source: SciCrunch Registry

http://www.biotech.ufl.edu/cytometry/

Cytometry core offers project consulting, experimental design and optimization as well as data analysis services. Provides tools and staff expertise for both live and fixed cell analysis. Provides FACS ARIA and SONY SH800 sorters to help users sort cells of interest. Offers microscopes for self service users. Microscope brands include Leica SP5 Confocal, Nikon Multiphoton Confocal system, Nikon Live cell Imaging platform, Olympus spinning Disk Confocal instruments, Keyence BZX800.

Proper citation: University of Florida ICBR Cytometry Core Facility (RRID:SCR_019119) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research/support/service-cores/chemical-genomics

Core provides collection of diversity-oriented, drug-like, and natural small molecules in non-redundant libraries, variety of automated liquid handling and assay detection systems such as EnVision Multiplate reader and ArrayScan HCA System, modern equipment for medicinal and analytical chemistry including NMR, LC-QTOF MS, HPLC, Peptide Synthesizer, and sophisticated chemoinformatics tools. Besides traditional high-throughput screening and hit compound optimization services, newly adapted technologies include arrayed CRISPR screening, phage display, and SAR by NMR.

Proper citation: Indiana University School of Medicine Chemical Genomics Core Facility (RRID:SCR_018785) Copy   

•   Source: SciCrunch Registry

http://www.pasteur.fr/biophysics

Provides services and instrumentation for characterization of biological macromolecules with technical and methodological expertise. Provides characterization of macromolecules including shape, folding, stability auto-association,and they interactions including stoichiometry,thermodynamic and kinetic parameters.

Proper citation: Pasteur Institute Biophysics of Macromolecules and their Interactions Core Facility (RRID:SCR_018267) Copy   

•   Source: SciCrunch Registry

https://www.research.uky.edu/pathology-core

Core facilitates COCVD projects by providing equipment and technical expertise to paraffin-embed and section tissue specimens and perform chemical staining of tissue sections to be examined, photographed and analyzed chromogenically by light microscopy.Training in immunohistochemical staining is available.

Proper citation: University of Kentucky College of Medicine, Lexington, Pathology Research Core Facility (RRID:SCR_018824) Copy   

•   Source: SciCrunch Registry

https://grcf.jhmi.edu/

Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.

Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy   

•   Source: SciCrunch Registry

https://animalcare.umich.edu/business-services/ulam-pathology-core/

Our core is affiliated with the Unit for Laboratory Animal Medicine (ULAM) at the University of Michigan-Ann Arbor. We provide animal pathology services in support of non-GLP preclinical, translational, or basic science studies. Services include histology preparation, immunohistochemistry, animal hematology and serum chemistry assays, digital slide scanning/image analysis, and pathology interpretation by board-certified veterinary pathologists. Our core mission is to reduce bias and increase rigor within non-GLP animal research by providing high quality, documented, pathology support that may not be otherwise accessible within individual laboratories. Our laboratory maintains internal SOPs, documented quality control practices, and accountability/chain-of-custody records for all submissions. Additionally, we participate in an external quality control program through the Veterinary Laboratory Association.

Proper citation: University of Michigan ULAM Pathology Core Facility (RRID:SCR_018823) Copy   

•   Source: SciCrunch Registry

https://childrenshospital.corefacilities.org/service_center/show_external/3145

Core with advanced instrumentation in Light and Electron Microscopy.Core provides confocal, multiphoton microscopy,electron microscopy,image analysis.

Proper citation: Harvard Medical School PCMM Microscopy Core Facility (RRID:SCR_018822) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/center-biospecimen-research-development

Assists researchers and clinicians with molecular and morphologic characterization of normal and disease tissues of interest in support of biomarker discovery and translational research. Offers both routine and advanced histology immunohistochemistry, in situ and whole slide scanning services.

Proper citation: New York University School of Medicine Center for Biospecimen Research and Development Histology Core Facility (RRID:SCR_018304) Copy   

•   Source: SciCrunch Registry

https://vbrn.org/proteomics-services/

Provides central resource of mass spectrometry based proteomics technologies to identify, characterize and quantify target proteins in various biological and biomedical samples. Provides mass spectrometry expertise for analyzing proteins and peptides for proteomics studies, support for data analysis from proteomics measurements, training in proteomics methods, and experimental design.

Proper citation: Vermont University Proteomics Core Facility (RRID:SCR_018667) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/mbcl/

Core services including UMass Oligo Discount Program which provides discounted oligos to researchers, Reagent Program offers discounted pricing on TAQMAN, qPCR reagents, enzymes, etc. from ThermoFisher (Life Technologies/Ambion), and Empirical Biosciences, Fragment Analyzer Service, Sequencing Library Preparation, Sanger Sequencing and GeneMapper/ARISA. Provides DNA fragment analysis, Genotyping, and SPR services on an ABI capillary sequencer, and DNA/RNA fragment analysis on the Advanced Analytical (Agilent) Fragment Analyzer.

Proper citation: University of Massachusetts Medical School Molecular Biology Core Facility (RRID:SCR_018263) Copy   

•   Source: SciCrunch Registry