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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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http://udn.nichd.nih.gov/

Understanding the mechanisms underlying the expression and perception of auditory communication in nonhuman primates provides important insights for understanding the neural systems that mediate nonverbal auditory communication in humans. Our research is devoted to understanding the changes in vocal behavior that are associated with maturation and social experience under normative conditions, and to investigating neural systems to define their roles in auditory communication. The anterior cingulate gyrus, in the frontal cerebral cortex, is an essential neural system for the expression of the primate isolation call, a structural and functional equivalent of the cry sounds of humans. Bilateral removal of this structure in adult squirrel monkeys resulted in a long-lasting inability to emit isolation calls. Partial recovery, often over many weeks, initially took the form of production of short, faint and uninflected versions of the typical isolation call. Humans suffering infarct damage to this region likewise show an initial recovery in the form of short, faint, monosyllabic sounds, suggesting that the anterior cingulate gyrus of nonhuman primates is the evolutionary precursor of a neural structure involved in human affective expression and speech. Our working model of isolation call production is that the anterior cingulate gyrus is the site where the command to produce this vocalization is initiated. Since the anterior cingulate region also has reciprocal connections with temporal lobe auditory cortex, a presumptive feedback pathway exists for registering commands to initiate vocalization with the temporal lobe cortex, which plays a major role in perceiving and decoding the acoustic details of species-specific vocalizations. At present, we do not know the role of the anterior cingulate gyrus in the production of infant vocalizations. However, we have found that neonatal removal of the amygdala, an important forebrain component of the limbic system, or portions of the inferotemporal gyrus, which sends projections to the amygdala, result in significant changes in the vocal behavior of infant rhesus macaques. Vocal development is a dynamic process, and a pattern shared by several nonhuman primates has emerged regarding the nature of this process. Infants are highly vocal during periods of brief separation from their caregiver, and we take advantage of this to document the range of vocalizations produced by infants of different ages. In the neonatal period, infants of 3 species of nonhuman primate (rhesus macaque, squirrel monkey and common marmoset) all produce sounds that vary widely in their acoustic structure. Many of these bear a striking similarity to sounds used in a variety of social settings by adults, suggesting that neural systems responsible for generating adult vocalizations are already in place during early infancy. As infants mature, their vocal behavior during brief periods of social separation becomes much more stereotyped. It isn't until much later in development, as individuals engage in a variety of social interactions with peers and adults, that the sounds expressed in early infancy begin to re-appear in adult contexts. The role of individual experience during development is currently being explored to determine the mechanisms leading to the acquisition of adult vocal skills.

Proper citation: NICHD Developmental Neuroethology - Laboratory of Comparative Ethology (RRID:SCR_000416) Copy   


http://www.tju.edu.cn/

A national university in China with degree programs that include engineering, economics, humanities, law and art at the undergraduate, graduate and doctoral level.

Proper citation: Tianjin University; Tianjin; China (RRID:SCR_000372) Copy   


http://www.tuskegee.edu/

A private, historically black university that offers degree programs at the undergraduate, graduate, doctoral and professional levels. The university has programs that include veterinarian studies, allied health, nursing, education

Proper citation: Tuskegee University; Alabama; USA (RRID:SCR_000373) Copy   


http://www.lse.ac.uk/

A public research university in London with an emphasis in social science degree programs such as law, mathematics, public affairs and international history. The university offers degrees at the undergraduate, graduate and doctoral level.

Proper citation: London School of Economics and Political Science; London; United Kingdom (RRID:SCR_000370) Copy   


http://international.tau.ac.il/

A public university in Israel with degree programs in areas such as arts, engineering, humanities, the law and medicine at the undergraduate and graduate level. The university has affiliated but independent schools that focus on specific areas such as music, environmental studies, dentistry, social work, education and neuroscience.

Proper citation: Tel Aviv University; Ramat Aviv; Israel (RRID:SCR_000371) Copy   


  • RRID:SCR_000377

    This resource has 500+ mentions.

http://www.lonza.com/

A supplier of various biochemical products for research in pharmacy and biotechnology as well as the specialty ingredients market. Examples of products include active pharmaceutical ingredients, stem cell therapies, drinking water sanitizers and agriculture services and products.

Proper citation: Lonza (RRID:SCR_000377) Copy   


http://www.usq.edu.au/

A public university in Australia that offers degree programs in business, law and education as well as health, engineering and the sciences at the undergraduate level. The university also does research at three research institutes and seven research centers which focus on a wide range of business, agricultural, scientific, environmental, and technological issues.

Proper citation: University of Southern Queensland; Queensland; Australia (RRID:SCR_000374) Copy   


  • RRID:SCR_000409

http://www.bioconductor.org/packages/release/bioc/html/rTANDEM.html

An R/Bioconductor package that interfaces the X!Tandem protein identification algorithm.

Proper citation: rTANDEM (RRID:SCR_000409) Copy   


http://www.allegheny.edu/

A private liberal arts college that offers degrees in social sciences, humanities and natural sciences at the undergraduate level.

Proper citation: Allegheny College; Pennsylvania; USA (RRID:SCR_000369) Copy   


  • RRID:SCR_000368

    This resource has 1+ mentions.

https://sites.google.com/site/beckerjeremie/home/nucleofinder

A software for a statistical approach for the detection of nucleosome positions in a cell population. The software identifies important features of nucleosome organization such as the spacing downstream of active promoters and the enrichment and depletion of GC/AT dinucleotides of in vitro nucleosomes.

Proper citation: NucleoFinder (RRID:SCR_000368) Copy   


  • RRID:SCR_000407

https://github.com/yongchao/flowPeaks

Software for fast and automatic clustering to classify the cells into subpopulations based on finding the peaks from the overall density function generated by K-means.

Proper citation: flowPeaks (RRID:SCR_000407) Copy   


http://saweb2.sabiosciences.com/manuals/GEArrayBrochure.pdf

THIS RESOURCE HAS BEEN DISCONTINUED, documented April 15, 2016. New GEArray Expression Analysis Suite 2.0 was released at Dec 21, 2006, please read Release Notices for details. SABiosciences' GEArray Analysis Suite uses advanced Java functionality. In order to experience full functionality of this Portal, the following free programs and upgrades for PC and Macs should be properly installed. PC Environment Downloads Browser compatibility is not an issue on Windows systems, so all operating systems running Windows 98 and above and either Internet explorer or Netscape should be fine. Java 1.4.1 or above is required--this should download automatically upon the first entry into the Portal. If this does not happen, Java 1.5 is available for download from the following URL: Java 1.5 Mac Environment Downloads Browser compatibility is an issue, and Mac Operating Systems prior to Panther are not able to fully take advantage of this Portal's functionality. These programs need to be downloaded and installed in a specific order as follows: Panther 10.3.5 (Operating System), Safari 1.2 (Compatible Internet Browser) and Java 1.4.2 (Java environment). Abstract. INTRODUCTION: Toll-like receptors (TLR) comprehend an emerging family of receptors that recognize pathogen-associated molecular patterns and promote the activation of leukocytes. Surgical trauma and ischemia-reperfusion injury are likely to provide exposure to endogenous ligands for TLR in virtually all kidney transplant recipients. METHODS: Macroarray (GEArray OHS-018.2 Series-Superarray) analyses of 128 genes involved in TLR signaling pathway were performed in nephrectomy samples of patients with chronic allograft nephropathy (CAN) and acute rejection (AR, vascular and non vascular). The analysis of each membrane was performed by GEArray Expression Analysis Suite 2.0. RESULTS: Macroarray profile identified a gene expression signature that could discriminate CAN and AR. Three genes were significantly expressed between CAN and vascular AR: Pellino 2; IL 8 and UBE2V1. In relation to vascular and non-vascular AR, there were only two genes with statistical significance: IL-6 and IRAK-3. CONCLUSION: Vascular and non-vascular AR and CAN showed different expression of a few genes in TLR pathway. The analysis of nephrectomy showed that activation of TLR pathway is present in AR and CAN. Sponsor. This work was supported by the inconditional grant from Fundao de Amparo a Pesquisa do Estado de So Paulo (FAPESP, 04/08311-6), from Conselho Nacional de Pesquisa e Desenvolvimento (CNPq) and from Fundao Osvaldo Ramos.

Proper citation: GEArray Expression Analysis Suite 2.0 (RRID:SCR_000282) Copy   


  • RRID:SCR_000286

    This resource has 10+ mentions.

http://proteinprophet.sourceforge.net/

Software that automatically validates protein identifications made on the basis of peptides assigned to MS/MS spectra by database search programs such as SEQUEST.

Proper citation: ProteinProphet (RRID:SCR_000286) Copy   


  • RRID:SCR_000316

    This resource has 1+ mentions.

https://github.com/mickaelleclercq/mirdup

A software used for the validation of pre-miRNAs predictions as well as predict the final structure of mature miRNA.

Proper citation: MiRdup (RRID:SCR_000316) Copy   


http://onlinelibrary.wiley.com/journal/10.1002/%28ISSN%291757-7012

Wiley Interdisciplinary Reviews series combines features of encyclopedic reference works and review journals in innovative online format. They are designed to promote cross-disciplinary research ethos while maintaining the highest scientific and presentational standards, but should be viewed first and foremost as evolving online databases of cutting-edge reviews.

Proper citation: WILEY Interdisciplinary Reviews (RRID:SCR_000392) Copy   


  • RRID:SCR_000310

http://purl.bioontology.org/ontology/TEO

Ontology for representing events, time, and their relationships.

Proper citation: Time Event Ontology (RRID:SCR_000310) Copy   


  • RRID:SCR_000311

http://purl.bioontology.org/ontology/VARIO

An ontology for standardized, systematic description of effects, consequences and mechanisms of variations.

Proper citation: Variation Ontology (RRID:SCR_000311) Copy   


http://purl.bioontology.org/ontology/SEDI

An ontology for DICOM as used in the SeDI project.

Proper citation: Semantic DICOM Ontology (RRID:SCR_000309) Copy   


  • RRID:SCR_000389

http://www.bioconductor.org/packages/release/bioc/html/QUALIFIER.html

Software that provides quality control and quality assessment tools for gated flow cytometry data.

Proper citation: QUALIFIER (RRID:SCR_000389) Copy   


  • RRID:SCR_000423

http://www.nitrc.org/projects/scribe/

Scribe encodes papers to populate the BrainMap Database

Proper citation: Scribe (RRID:SCR_000423) Copy   



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