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http://www.progeriaresearch.org/cell_tissue_bank.html

The PRF Cell & Tissue Bank provides medical researchers with genetic and biological material from Progeria patients and their families, so that research on Progeria and other age-related diseases can be performed. We''ve been hard at work with the families and their physicians to gather these precious biological materials. As you know, Hutchinson-Gilford Progeria Syndrome is an extremely rare condition. Thus while access to cell lines is essential for studying the biology and genetics of the disorder, there are very few cell lines in existence. Because an integral part of PRF''s mission is to stimulate interest in, and NIH funding opportunities for, Progeria research, there is an increased need for cell lines. The PRF Cell Bank will ensure that need is met! The goals of The PRF Cell & Tissue Bank are to promote: * Sufficient availability of cells for approved research projects * Incentive for new research projects * Study of the biochemical basis for Hutchinson-Gilford Progeria Syndrome * Discoveries leading to new treatments for children with Progeria * Discovery of a cure for Progeria

Proper citation: Progeria Cell and Tissue Bank (RRID:SCR_004194) Copy   

•   Source: SciCrunch Registry

http://www.nsabp.pitt.edu/NSABP_Pathology.asp

The NSABP (National Surgical Adjuvant Breast and Bowel Project) Tissue Bank is the central repository of tissue samples (stained and unstained slides, tissue blocks, and frozen tissue specimens) collected from clinical trials conducted by the NSABP. The main scientific aim of the NSABP Division of Pathology is to develop clinical context-specific prognostic markers and predictive markers that predict response to or benefit from specific therapeutic modality. To achieve this aim, the laboratory collects the tumor and adjacent normal tissues from cancer patients enrolled into the NSABP trials through its membership institutions, and maintain these valuable materials with clinical follow-up information and distribute them to qualified approved investigators. Currently, specimens from more than 90,000 cases of breast and colon cancer are stored and maintained at the bank. Paraffin embedded tumor specimens are available from NSABP trials. We currently do not bank frozen tissues. All blocks are from patients enrolled in prospective NSABP treatment protocols and complete clinical follow up information as well as demographic information is available. Depending on the project, unstained tissue sections of 4-micrometer thickness, tissue microarrays, or stained slides are provided to the investigators in a blinded study format. Any investigators with novel projects that conform to the research goals of NSABP may apply for the tissue. Please refer to the NSABP Tissue Bank Policy to determine if your project conforms to these goals. Priority is given to NSABP membership institutions who regularly submit tissue blocks.

Proper citation: National Surgical Adjuvant Breast and Bowel Project Tissue Bank (RRID:SCR_004506) Copy   

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http://biostorage.com/

At BioStorage Technologies, our mission is to provide our clients with world class, biorepository services, exceeding clients����?? expectations of service, value and quality while setting the industry standard for the storage, management & logistics of samples. Offering onsite or outsourced management of sample assets, BioStorage Technologies manages the complete life-cycle of samples. With a team of global sample experts, state-of-the-art temperature-controlled storage facilities, and a real-time web-based sample intelligence and tracking system, the company supports customers in maximizing opportunities, minimizing risk and reducing the cost of sample management. The unique advantages of BioStorage Technologies * Consulting����??Expert consulting on Good Storage Practices, global transport standards, standard operating procedures and business continuity planning to mitigate risk and optimize your resources * Consolidation����??Comprehensive management of the sample lifecycle through consolidation of sample data into one technology system for faster retrieval, more flexible tracking and enhanced security * Control����??Enhanced control of sample asset data within one technology system, ISISS, for faster go/no-go decisions and expansion into future research * Compliance����??Improved chain of custody of your samples and easier audit trail tracking for adherence to quality and regulatory compliance standards in order to support product approvals * Cost-Reduction����??Reduced cost of sample management and increased project ROI through more efficient sample and data management processes, enabling you to refocus resources on your core competencies BioStorage Technologies, Inc. was founded in 2002 and is privately held and headquartered in North America in Indianapolis, Indiana with an additional full-service site in Europe near Frankfurt, Germany.

Proper citation: BioStorage Technologies (RRID:SCR_004302) Copy   

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https://www.dtmi.duke.edu/for-researchers/technology-cores/duke-biobank

The Duke Biobank is an institutional resource that combines well-annotated clinical data with a standardized, regulation compliant, cost efficient repository for both fluid and tissue, connected via information systems to a large scale, long-term biobank in Kannapolis, in order to foster breakthroughs in research; while ensuring the strictest adherence to ethical standards and regulations. Our goal is to work with investigators to maintain biorepository collections which are in compliance with all relevant local, regional and national and IRB biobanking standards. Capabilities * Provide expert consultation in planning and design of biobanking programs * Access, process, aliquot, store and distribute a wide array of liquid and tissue biological samples * Maintain informatics capabilities to accurately and efficiently track samples and link to clinical and laboratory assay data * Use the Duke Biobanking Guidelines document (in development) as guidance on scientific, ethical/legal, and operational to ensure quality and standardization of biospecimen collection * Minimize redundancy of infrastructure, as appropriate, across Duke Medicine. Duke University offers both on- and off-campus options for investigators seeking biobanking services. Our biobanking facilities are: * The Center for Human Genetics (CHG). Serves as the primary on-campus biobank for liquid sample storage for Duke Medicine, and as a portal between Duke and the LabCorp Biobank. * Duke Hospital South Tissue Bank. Serves as a sample portal for the Duke Biobank, and as the primary facility for tissue storage for Duke Medicine. ** DCCC Tissue & Blood Procurement ** IGSP Biospecimen Repository * LabCorp Biorepository. Located in Kannapolis, NC, this is the preferred storage center for large-scale, infrequently accessed sample collections

Proper citation: Duke Biobank (RRID:SCR_004304) Copy   

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http://www.ucl.ac.uk/cancer/medical-genomics/clinepi

Aims to carry out an integrated (epi)genomic analysis of the NET BioBank established at the Royal Free and UCL Hospitals to identify new biomarkers for translation into diagnostics and therapeutics. The Neuroendocrine Tumour (NET) Unit at the Royal Free Campus of UCL Hospitals has an international reputation for the management of neuroendocrine tumor patients. It currently receives around 10 new referrals per month and has an active patient cohort of over 800 patients. We receive referrals from across the UK as well as from abroad. It is the designated center for NETs within the North London Cancer Network. In order to improve both treatment and outcome in Neuroendocrine Tumors (NETs), better understanding of their biology and the biological pathways involved is imperative (reviewed in (Modlin et al., 2008)). Currently, the use of targeted treatments is limited and management challenging due to the lack of knowledge of the molecular pathogenesis and mechanistic regulation of these tumors (Barakat et al., 2004). Due to the rarity of NETs and difficulty in obtaining fresh tissue and archival samples, very little is known about the (epi)genetic and germline mutations associated with neuroendocrine tumors ����?? which encompass a clinically and genetically heterogeneous group. To date, studies have been small and under-powered. Clinical trials have included small patient numbers and are often non-randomized phase II trials comparing a new therapy against a non-standardized first line treatment. Initially we will undertake genome-wide methylation analysis on our entire cohort of neuroendocrine tumors in order to determine the methylation profiles of differing NET types. This will improve diagnostic accuracy and potentially identify new therapeutic targets and biomarkers. These studies will be performed on high-throughput analysis platforms based on micoarrays and next-generation sequencing. In parallel, we will analyze the mRNA expression profiles of these tumors to enable integrated (epi)genomic analysis of these intriguing tumors.

Proper citation: Neuroendocrine Tumors Biobank (RRID:SCR_004380) Copy   

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http://www.uab.edu/medicine/tcbf/sporebb-tpsfsidebar

A biomaterial supply resource which stores and provides ovarian, breast, pancreatic, and cervical tissue samples and fluids to cancer researchers. The UAB Tissue Collection and Banking Facility collects tissue samples for the UAB Ovarian, Breast, Pancreatic, and Cervix SPORE banks. Samples from the former Ovarian SPORE bank are available to UAB Cancer Center members via the Tissue Procurement Shared Facility, and to other researchers via the Cooperative Human Tissue Network.

Proper citation: UAB SPORE Biorepository Banks (RRID:SCR_004419) Copy   

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http://htrc.uchicago.edu/biospecimen_bank.php

Biospecimen banking (BSB) involves collecting, processing, storing and distributing of human or animal tissues and body fluids of molecular grade. Human tissues and body fluids are banked in compliance with IRB approved protocols without compromising the diagnostic process and maintaining donor confidentiality (HIPAA compliant). Investigator-driven biobanking initiatives are of paramount importance at the University. The BSB provides investigators with the infrastructure to establish organ-specific biobanks in a centralized location. This arrangement allows for minimal duplication of costs, as well as establishing a working template for all tissue collections. The BSB has grown exponentially, and has a strong team of experienced personnel banking tissues for clinical trials, investigator-driven projects, and future biospecimen-based research. In addition, the BSB now collects and stores saliva, urine, blood, plasma, serum, and derivatives. The BSB is a complex process, requiring multiple interacting systems to ensure the scientific quality of procured tissue, and body fluids, patient confidentiality, adherence to good clinical practices, and regulated disbursement of biospecimens to approved investigators. They are also aware that policies, HIPAA guidelines, and federal and state tissue procurement regulations may change, and will be fully compliant with all new regulations.

Proper citation: University of Chicago Human Tissue Resource Center Biospecimen Banking (RRID:SCR_004418) Copy   

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https://healthsciences.ucsd.edu/research/moores/shared-resources/biorepository/Pages/default.aspx

The Biorepository contains plasma, serum, RNA stabilized buffy coat, urine, viable tumor samples, and formalin-fixed paraffin-embedded tumor; all with associated clinical information. These can be provided to investigators with Cancer Sample Banking Committee approval (IRB approval is also required for projects requesting ongoing sample collection or clinical annotation.) Urine and blood-derived specimens are available from a wide variety of cancer cases and cancer-free controls. Tumor sample availability is more limited and predominately from breast and gastrointestinal malignancies. Samples are collected from consented subjects and de-identified clinical information on the subjects is collected over time. Subjects are consented for research germ line genotyping. Access to the clinical annotation is determined based on need as justified in each investigator''s request or protocol. Anonymized samples from the biorepository are available compliant with UCSD HRPP exempt category 4.

Proper citation: UC San Diego Biorepository (RRID:SCR_004256) Copy   

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http://sunnybrook.ca/research/?page=sri_core_tbank_home

Sunnybrook Research Institute''s tumour bank provides a mechanism for the optimal collection, storage and distribution of human tissue for investigative purposes. We collect both freshly frozen and formalin-fixed paraffin-embedded tumour and normal samples, retrospectively and prospectively (informed consent and confidential consent is obtained from patients before sample collection). We offer the 1. Distribution of tissue and data to interested investigators after approval from the institutional research ethics board and 2. Collaboration with various research investigators. Our mandate is to design, implement and manage the structures and processes to ensure the timely provision of tissue samples and associated data. We are currently building bank on four disease sites: breast, prostate, colorectal, gynecological. We are also creating and maintaining a database with a tissue tracking and inventory system, using TissueMetrix software.

Proper citation: Sunnybrook Tumour Bank (RRID:SCR_004138) Copy   

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http://www.lerner.ccf.org/gmi/gmb/

A biorepository is a place where investigators can deposit and store biological material, in this case samples derived from patients. Moreover, the Genomic Medicine Institute (GMI) takes this basic concept and elevates it to make the Genomic Medicine Biorepository (GMB) a full-service processing and banking laboratory that serves as the foundation for evidence-based research for the GMI, the Cleveland Clinic, and our collaborators. The process relies on a team of multi-disciplinary professionals coordinating their efforts in order to streamline medical research. This begins with dedicated physicians and genetic counselors identifying individuals with specific medical conditions indicating the possibility of genetic involvement. Once identified, biological material (e.g. blood, tissue, or saliva) is collected under the care of the patient''s doctor or by our clinicians and sent to the GMB. Once in the lab, the patient and their samples are assigned a unique identifier (to protect the patient''s personal information) and logged into a central database. This unique identifier accompanies all samples processed and banked for that individual. The specimens are then processed into research-relevant samples using proven laboratory techniques and state-of-the-art quality control practices. These samples include the isolation of DNA and RNA from white blood cells for genetic studies; collection of plasma for proteomic studies; and initiated immortalized cell lines from lymphocytes for in-vitro studies and biochemical research. These cell lines are able to be indefinitely stored in cryogenic suspension and are invaluable as a renewable resource for genetic and biochemical research. The GMB also processes genetic material from various tissues (both fresh and archived). Charis Eng, MD, PhD, Chair and Director of the GMI, has been the faculty oversight person of a human biorepository for the last eight years. Since then, our biorepository has received, cataloged, processed, and banked, in excess of 25,000 specimens. These samples are of numerous tissue types from patients and their family members located all over the world. Our biorepository has managed samples that have resulted in more than 150 original peer reviewed articles and greater than $25 million total direct costs in extramural funding over the last four years alone.

Proper citation: Cleveland Clinic Genomic Medicine Biorepository (RRID:SCR_004136) Copy   

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https://www.bips-institut.de/en/research/biobank.html

Biobank that contains more than 50,000 blood, urine and saliva samples as well as tissue materials from epidemiological field studies. The samples and DNA collected in various studies are increasingly being used for the investigation of genetic, environmental and life-style associated factors in the etiology and prognosis of cancer and other chronic diseases such as obesity, diabetes and metabolic syndrome.

Proper citation: Leibniz Institute for Prevention Research and Epidemiology Biobank (RRID:SCR_004094) Copy   

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http://www.lionseyeinstitute.org/about-us/

A nonprofit ocular research center with the largest eye bank in the world that provides eye tissue for research and transplantation to ophthalmic specialists and surgeons nationwide. They empower researchers to conduct real-time studies of healthy and diseased ocular tissue leading to a greater understanding of the events that lead to blindness. Their mission is to improve visual outcomes and quality of life for those who are blind or visually impaired through innovative ocular endeavors.

Proper citation: Lions Eye Institute for Transplant and Research (RRID:SCR_004008) Copy   

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https://moffitt.org/research-science/shared-resources/tissue/

A central tissue repository at Moffitt specializing in protocol-driven human tissue collection, storage, processing and dissemination. Tissue Core provides investigators with access to high quality, well-annotated human specimens obtained from representative of the patient populations. The advent of powerful molecular technologies has opened the door to developing more effective treatments of patients with cancer. Access to high quality specimens with associated clinical, treatment, recurrence outcome data will be critical to developing and validating the tests needed for diagnosis and prediction of response to therapy. Since its commencement in 1993, the Tissue Core has collected more than 8,000 cases of human liquid cancers and solid primary and metastatic tumors both malignant and benign with adjacent normal, from variety of sites and diagnoses. Collected samples are mostly remnant tissues obtained from patients undergoing therapeutic surgical procedures at the Center. The core also ensures tissue release compliance with USF-IRB and Privacy Board recommendations. * Protocol driven sample collection, processing and distribution * Collection of sample and patient demographic information. * Nucleic acid extractions from tissue sections, FNA, core biopsies blood and bone marrow. * Histology services: H&E slides, staining, sectioning, paraffin blocks, OCT blocks, sample microdissection * WBC, plasma and serum isolation. * Project development and support: Facility staff provides advice and guidance to researchers.

Proper citation: Moffitt Cancer Center Tissue Core (RRID:SCR_004406) Copy   

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http://www.tumorbank.org/index.php

Since 1995 the Tumorbank Basel Foundation (German: Stiftung Tumorbank Basel) is a non-for-profit foundation acting in cancer translation research. The purpose of the Tumorbank Basel Foundation is to support in promoting optimization of decision making process for the management of solid cancer personalized treatment modalities to the benefit of the patient. Our Aims: * Acquisition and storage of biological material and clinical data of patients suffering of solid cancer diseases in particular breast and prostate cancer. * Promoting and supporting cancer research using the acquired material and data for clinical studies and translational research. * The development of molecular tumor analyses / tools for cancer patients and the performance of the resulting diagnostic services for personalized treatment modalities. The Tumorbank Basel Foundation has acquired * Data about more than 10''000 breast cancer patients * Data comprise clinical and pathological (histology & IHC) characteristics and biochemical (continuous quantified protein expression levels) features, which are available for almost all samples as well as clinical follow-ups now available for more than 2''000 patients * The RNA expression level of 65 genes has been assessed in >800 samples by Real-Time PCR (317 retrospectively in cases with follow-up, the remaining on a routine basis, prospectively since 2004) The Tumorbank Basel Foundation is storing in Freezers at - 80 degrees C * Ca. 6''000 fresh frozen tissue samples of breast cancer patients * Ca. 9''000 particulate fractions (cytosol / membrane) of all samples analyzed * Ca. 1''000 paired non-malignant adjacent tissue material samples * More than 1''000 extracted RNA samples of good quality * Serum and plasma collection from patients has been started since 2005 All data are stored in a relational SQL data bank using an application. The Tumorbank Basel Foundation is collaborating with several pathology institutes allowing to perform studies correlating results obtained from fresh frozen and paired paraffin embedded tissue samples. The Tumorbank Basel Foundation has started a prostate carcinoma project in Collaboration with the ZeTuP (www.zetup.ch) and pathology institute of St. Gallen. Fresh frozen samples of more than 150 prostate carcinoma patients have been collected and are under investigation.

Proper citation: Tumorbank Basel Foundation (RRID:SCR_004962) Copy   

•   Source: SciCrunch Registry

http://www.brain-net.net/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 28,2022. A network of several university centers in Germany that classifies neurological and psychiatric disorders neuropathologically and collects and provides brain tissue for research. The aim and task of the Brain-Net are: the collection of clinically and neuropathologically well-characterized brain tissue samples; the standardization of neuropathological diagnoses according to internationally accepted criteria; and providing a basis for future research projects using genetic, epidemiological, biometric and other issues to neurological and psychiatric disorders.

Proper citation: Brain-Net (RRID:SCR_005017) Copy   

•   Source: SciCrunch Registry

http://www.alabamaorgancenter.org

The Alabama Organ Center (AOC) is the federally designated organ procurement organization for the state of Alabama. We work with all of the hospitals in the state to coordinate their donation services. Like all organ procurement organizations, the AOC is a non-profit organization. We provide a variety of services: * Hospital education * Public education * Screening of potential donors * Coordination of the donation process * Family support The AOC is committed to providing a better quality of life for those who require an organ or tissue transplant, while respecting the families who share the gift of life.

Proper citation: Alabama Organ Center (RRID:SCR_004721) Copy   

•   Source: SciCrunch Registry

http://www.ilsbio.com/

THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 17, 2021.Biospecimens and support services to advance translational research including a wide range of specimen types, including matched sets of normal and diseased tissue, Formalin-Fixed, Paraffin-Embedded (FFPE), blood, and serum, focusing primarily on cancer. They stock a wide range of sample formats to help meet research goals quickly and on budget. Collections are preformed to be ideal for a wide range of studies including genomic, proteomic, molecular and histologic analysis. ILSbio provides tissue and tissue derivatives that are high quality, cost effective and procured in compliance with current and anticipated regulations. The company obtains its clinical specimens under strict IRB approved protocols with informed consent and the utmost attention to issues of patient safety, anonymity and confidentiality. Clinical and pathological data is available for all specimens. Researchers use the tissue products at all levels of scientific study ranging from large pharma and biotech organizations to small labs and university research facilities. They also participate in wholesale distribution to other bio-banking organizations.

Proper citation: ILSbio (RRID:SCR_004682) Copy   

•   Source: SciCrunch Registry

http://www.cryobank.com

Founded in 1977, California Cryobank (CCB) is a full-service sperm bank providing a comprehensive resource for frozen donor sperm, private semen cryopreservation, and specialized reproductive services (including egg and embryo storage and artificial insemination guidance). We are extremely proud of our 30 years of reproductive success. The demand for expert services has grown exponentially as discussion of reproductive challenges has continued to become more mainstream. At California Cryobank we understand that regardless of how much information and education you bring to the process, there can still be significant apprehension accompanying such big steps as sperm donation and donor insemination. CCB''s commitment to making our clients as comfortable as possible is what sets us apart and makes us so much more than just another sperm bank. Our services are entirely patient-centric; from the education that we provide����??answering questions and providing step-by-step timetables that let patients know what to expect in the weeks and months to come from donor sperm selection through insemination����??to the guidance that we offer. Our team is comprised of physicians, lab technicians, genetic counselors, Client Service Consultants, and Donor Matching Consultants. Every facet of our services is completely and expertly led by one of our experienced and compassionate team members. And while our sperm donor program is the foundation of our service, California Cryobank provides a full range of services for our clients including cord blood banking and access to our CCB Sibling Registry.

Proper citation: California Cryobank, Inc. (RRID:SCR_004684) Copy   

•   Source: SciCrunch Registry

http://www.umiamitb.org

Established in 1970, the University of Miami Tissue Bank (UMTB) is the oldest academic institution of its kind in the United States. UMTB came about and evolved in an effort to provide safe and effective bone and soft tissue grafts to patients long before allograft bone transplantation was widely accepted. UMTB has always been focused on safety and the advancement of knowledge in allograft use. More scientific peer-reviewed articles, book chapters and innovations have come from UMTB either directly or indirectly than from any other organization of its kind. UMTB continues to be a leader in transplantation research and has maintained an impeccable safety record. As the only university-run tissue bank, UMTB works closely with surgeons and basic science investigators to advance the field of bone and soft tissue transplantation. Our scientific endeavors include clinical trials to confirm and improve graft efficacy for oral surgery, orthopedic tumor and spine surgery, and sports injuries. When warranted, we engage commercial entities for these studies. As a multidisciplinary organization of surgeons, pathologists, scientists and technicians, we have safely recovered, processed, distributed and implanted aseptically processed bone, cartilage and soft tissue grafts in thousands of patients. We make extraordinary efforts to ensure aseptic recovery and processing to protect the biologic activity, integrity, bio attributes, and safety of the graft. We believe that the American Association of Tissue Banks (AATB) has adopted appropriate guidelines for Tissue Banking in the United States and the University of Miami is a proud member of this organization.

Proper citation: University of Miami Tissue Bank (RRID:SCR_004560) Copy   

•   Source: SciCrunch Registry

http://worldbiobank.net/

Founded by the physician partners of ACORN, Inc. (Accelerated Community Oncology Research Network), World BioBank embraces forward-thinking technology and a strong commitment to the advancement of bioscience. The World BioBank collects cancer samples, normal samples, and other non-neoplastic diseases. Data available include sample-specific data, patient-specific data, and study-related data. * SOLID TISSUES (snap frozen and matched formalin-fixed paraffin embedded diseased and normal internal controls) from: Surgical resections, Image-guided biopsies, Bone marrow biopsies, Endoscopic biopsies * LIQUID TISSUES: Peripheral blood, Genomic DNA (from buffy coat), Plasma, Serum World BioBank is committed to marrying samples to a wealth of longitudinal medical data and tissue-specific data.

Proper citation: World BioBank (RRID:SCR_004958) Copy   

•   Source: SciCrunch Registry