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https://medschool.cuanschutz.edu/immunology-and-microbiology/core-labs/gemm-core

Core provides full-service mouse genetic engineering support to researchers.Helps to select model for your research program, design and build any requisite constructs and reagents, and produce live mice. The most popular requests are for CRISPR-based gene edited mice and transgenic mice. Services include creation of engineered alleles for knockouts, conditional knockouts, SNP knockins, tag and marker insertions, deletions of up to 300kb, duplications, and transgenic alleles. These novel mouse models have been made on a wide spectrum of genetic background strains, including but not limited to C57BL/6J, C57BL/6N, NOD, BALB/cJ, FVB/Crl, NSGS, various 129 substrains, collaborative cross strains, and on mice that are already genetically modified. Breeding and genotyping program supports breeding to establish germline transmission and can also create cohorts for investigators. Provides strain cryopreservation, rederivation and rescue services, as well as cryostorage.

Proper citation: University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models Core Facility (RRID:SCR_025491) Copy   

•   Source: SciCrunch Registry

https://mpimagingcore.weebly.com/

Imaging Core provides equipment and services available to all UM researchers. Offers training and assistance in range of light microscope techniques including spinning disk confocal, super resolution imaging, lightsheet imaging of cleared organ and stereology systems. Offers image analysis software (Imaris neuroscience package) including 3D image rendering, surface creation, spot detection and filament tracing.

Proper citation: University of Miami The Miami Project Imaging Core Facility (RRID:SCR_025492) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cancer-bioinformatics/

Provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies.

Proper citation: University of Pittsburgh Hillman Cancer Center Cancer Bioinformatic Services Core Facility (RRID:SCR_025356) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/biological-sciences/services/mf/index.html

Core services include paraffin embedding and histology, epifluorescence microscopy and confocal LSM, SEM and TEM sample prep and imaging.

Proper citation: University of Alberta Biological Sciences Advanced Microscopy Core Facility (RRID:SCR_025329) Copy   

•   Source: SciCrunch Registry

https://vet.purdue.edu/ctr/

Core facilities pre-clinical studies of orthopedic devices intended for animal and human use, clinical studies of treatment and prevention of respiratory diseases in horses and animal clinical trials evaluating the treatment of bladder cancer in Scottish Terriers, an animal model of human bladder cancer.

Proper citation: Purdue University Center for Comparative Translational Research Core Facility (RRID:SCR_025541) Copy   

•   Source: SciCrunch Registry

https://cancer.iu.edu/research/shared-facilities/pmtc/crt.html

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

Proper citation: Indiana University School of Medicine Cellular Response Technologies Core Facility (RRID:SCR_025535) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/drug-discovery/resources/cgf/index.php

Provides access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development

Proper citation: Purdue University Chemical Genomics Core Facility (RRID:SCR_025537) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/service-cores/facilities/proteomics

Provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.

Proper citation: Indiana University School of Medicine Proteome Analysis Core Facility (RRID:SCR_025538) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/service-cores/facilities/genome-editing

Provides access to genome editing technologies by assisting with generation of genetically modified mouse models and cell lines.

Proper citation: Indiana University School of Medicine Genome Editing Center Core Facility (RRID:SCR_025553) Copy   

•   Source: SciCrunch Registry

https://handsinautism.iu.edu/

Provides evidence-based services, training, coaching and consultation across range of local community and state stakeholder networks e.g., families, medical providers, school personnel, community organizations. This involvement and integration in addressing the behavioral, educational, and vocational needs of consumers across a range of ages i.e., early childhood through adulthood, functioning and disability types has assisted in: providing consultative expertise related to assessment and intervention with autism spectrum disorder and related developmental e.g., developmental and/or intellectual disabilities or neurodevelopmental disorders; reaching extensive audience for recruitment efforts; facilitating efforts related to community-based mixed methods, clinical trials and other research endeavors e.g., survey development and dissemination, behavioral assessment and intervention related to individuals with ASD/DD/ID across lifespan.

Proper citation: Indiana University School of Medicine HANDS In Autism Interdisciplinary Training and Resource Center Core Facility (RRID:SCR_025554) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/service-cores/facilities/histology

Provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility. Histology Core is core facility of the Indiana Center for Musculoskeletal Health and part of the Bone and Body Composition Core of the Indiana Clinical Translational Sciences Institute (CTSI). Histology Core provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.

Proper citation: Indiana University School of Medicine Histology and Histomorphometry Core Facility (RRID:SCR_025556) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research-centers/neurosciences/Core-Services/Electrophysiology-Core

Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.

Proper citation: Indiana University School of Medicine Electrophysiology Core Facility (RRID:SCR_025546) Copy   

•   Source: SciCrunch Registry

https://biostats.indiana.edu/

Provides study design and data analysis for health-related research, including grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.

Proper citation: Indiana University Bloomington Biostatistics Consulting Center Core Facility (RRID:SCR_025530) Copy   

•   Source: SciCrunch Registry

https://birck.research.purdue.edu/

Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories.

Proper citation: Purdue University Birck Nanotechnology Center Core Facility (RRID:SCR_025532) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research-centers/computational-biology-bioinformatics/bioinformatics-core

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

Proper citation: Indiana University School of Medicine Bioinformatics Core Facility (RRID:SCR_025526) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/biostatistics

Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

Proper citation: Indiana University School of Medicine Biostatistics and Health Data Science Core Facility (RRID:SCR_025528) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/service-cores/facilities/electron-microscopy

Offers cryo-electron microscopy, transmission electron microscopy, and scanning electron microscopy. Provides technical services to help design and then implement experiments needing each type of microscopy.

Proper citation: Indiana University School of Medicine Center for Electron Microscopy Core Facility (RRID:SCR_025587) Copy   

•   Source: SciCrunch Registry

https://transgene.nd.edu/

Core develops and uses gene-targeting technology to investigate pathophysiological roles of genes of blood coagulation, anticoagulation, and fibrinolytic pathways in hemostasis, with associated relevance to embryonic development, cancer, infection, and inflammation.

Proper citation: University of Notre Dame Keck Center for Transgene Research Core Facility (RRID:SCR_025588) Copy   

•   Source: SciCrunch Registry

https://lmic.indiana.edu/

Provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.

Proper citation: Indiana University Bloomington Light Microscopy Imaging Center Core Facility (RRID:SCR_025597) Copy   

•   Source: SciCrunch Registry

https://nmr.nd.edu/

Core supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput.

Proper citation: Notre Dame University Magnetic Resonance Research Center Core Facility (RRID:SCR_025599) Copy   

•   Source: SciCrunch Registry