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https://www.med.upenn.edu/ipsccore/

Provides resources for disseminating human pluripotent stem cell technology within UPenn and surrounding research communities. �Our services include derivation of patient specific iPSCs, genome engineering of stem cell lines using CRISPR/Cas9 technology, and lineage specific differentiation of iPSCs/hESCs in 2D and 3D organoid culture.�Core has large collection of patient derived iPSC lines and cell lines of gastrointestinal tract (esophageal, pancreatic and intestinal) available to users.�Committed to training investigators in stem cell culture techniques and providing quality tested stem cell reagents to users.

Proper citation: University of Pennsylvania Perelman School of Medicine Induced Pluripotent Stem Cell Core Facility (RRID:SCR_022426) Copy   

•   Source: SciCrunch Registry

https://qb3.berkeley.edu/facility/ctaf-htsf/

Facility provides expert staff for training, services, and cell culturing space for HT automated cell seeding, liquid handling equipment, multi label plate reader and high content automated confocal imaging for any type of multi well, multi conditional mammalian cell experiments.

Proper citation: University of California at Berkeley QB3 High Throughput Screening CoreFacility (RRID:SCR_022304) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/ris/

Shared resource machine shop serving various University of Pennsylvania Schools and Departments. Assists researchers to design and construct both laboratory and clinical instruments.

Proper citation: University of Pennsylvania Perelman School of Medicine Research Instrumentation Shop Core Facility (RRID:SCR_022424) Copy   

•   Source: SciCrunch Registry

https://it.hms.harvard.edu/rc/core

Promotes deeper collaboration across Harvard biomedical research ecosystem.This includes improved capabilities and performance by establishing more transparent and sustainable IT services for our research community.

Proper citation: Harvard Medical School Research Computing Core Facility (RRID:SCR_022289) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/

Provides Becton Dickinson LSR II flow cytometer equipped with four lasers.Blue laser can be used to detect forward and side scatter and 4 colors (eg., FITC/Alexa 488, PE, PerCP-CY55, PE-CY7), red laser can be used to detect 2 colors (e.g., APC and APC-CY7), violet laser can be used to detect 2 colors (e.g., Pacific blue, Am cyan) and a UV laser which can also be used to detect 2 colors (e.g., INDO1 blue, Indo1-violet/DAPI). The instrument is located in Room 330 in the Levy Building (240 South 40th Street).

Proper citation: University of Pennsylvania Penn Dental Medicine Flow Cytometry Core Facility (RRID:SCR_022443) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/polymeric-and-optical-materials-characterization-shared-facility

Facility specializes in material characterization of polymers, hydrogels, liquid crystals, and composites.

Proper citation: University of Colorado Boulder Polymeric and Optical Materials Characterization Shared Core Facility (RRID:SCR_022288) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models

Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�

Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/flow-image-cytometry

Provides advanced flow cytometric and morphology services at cellular and subcellular levels of resolution.Services include investigator access to equipment, education and consultation, comprehensive sample processing, data acquisition and data analysis, luminex cytokine, chemokine and growth factor quantification, and core flow cytometry services for investigator and biotech sponsored clinical trials.

Proper citation: Roswell Park Cancer Institute Flow and Image Cytometry Shared Resource Core Facility (RRID:SCR_022313) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/centers-laboratories/center/center-for-host-microbial-interactions

Offers consultation and laboratory services for high-throughput sequencing (HTS) experiments, with particular expertise and interest in microbiome/metagenome and RNA-seq applications. Provides instrumentation, including Illumina NextSeq 2000 and single cell platforms from 10X genomics and 1CellBio. Offers full service options, as well as hands on instruction for trainees who want to learn best practices for wet lab aspects of genomics experiments. Offers consultation services for all phases of HTS studies, from study design to bioinformatics analysis.

Proper citation: University of Pennsylvania Penn Vet Center for Host Microbial Interactions Core Facility (RRID:SCR_022434) Copy   

•   Source: SciCrunch Registry

https://pathbio.med.upenn.edu/pbr/portal/flowcyto/

Flow cytometry shared resource laboratory at the University of Pennsylvania. Facility has instruments, which include analyzers, cell sorters, small particle detectors, dual fluorescence cell counter/viability instrument, tissue dissociator for cell preparation. Provides on-site and off-site support to instrument users, including analyzer and cell sorter training. Core's Research and Development team collaborates/consults with principal investigators in developing high-dimensional panels, as well as staining, acquisition, and analysis.

Proper citation: University of Pennsylvania Perelman School of Medicine Cytomics and Cell Sorting Resource Laboratory Core Facility (RRID:SCR_022376) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/electronmicroscopyresourcelab/

Training and service facility dedicated to providing both conventional transmission electron microscopy of cells and tissues and state of the art cryo-electron microscopy and cryo-electron tomography for structural investigation of macromolecules and cells.

Proper citation: University of Pennsylvania Perelman School of Medicine Electron Microscopy Resource Lab Core Facility (RRID:SCR_022375) Copy   

•   Source: SciCrunch Registry

https://bioinfo.med.upenn.edu/

Core provides bioinformatics services that include data analysis and consultation and building of efficient pipelines that handle various biomedical data including Next-Generation Sequencing (NGS) data.

Proper citation: University of Pennsylvania Perelman School of Medicine Bioinformatics Core Facility (RRID:SCR_022374) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cdbmicroscopycore/

Core provides personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to assistance with image data analysis. Facility houses confocal microscopes, Bruker Vutara 352 super resolution system, Zeiss Z.1 Lightsheet system, three widefield light microscopes, and several computers dedicated to image processing and analysis. Offers scanning electron microscope sample preparation and imaging.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Developmental Biology Microscopy Core Facility (RRID:SCR_022373) Copy   

•   Source: SciCrunch Registry

https://www.cceb.med.upenn.edu/crcu

Provides services essential for conduct of clinical research projects, including Phase I-IV, multi-center, randomized, clinical trials, registry, and cohort studies. Provides custom development solutions when appropriate for project needs and has experience in managing multi institution research networks as data coordinating center and offer expert staff with prime focus on quality data.�Specializes in study design and development, site management and training, data collection, processing, quality control, regulatory requirements and reporting, database development, administration, security, data storage and proposal development.

Proper citation: University of Pennsylvania Perelman School of Medicine Clinical Research Computing Unit Core Facility (RRID:SCR_022404) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cfar/virus-reservoirs.html

Facility provides comprehensive viral and molecular support in area of basic, translational and clinical HIV research, consultation, training, and mentoring.Is available to develop customized viral and molecular support services as needed. Offers deep sequencing support and single genome amplification services.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for AIDS Research Virus and Reservoirs Core Facility (RRID:SCR_022403) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/chps/

CHPS is comprised of several Clinical Research Cores designed to facilitate research process. Provides resources, environment, operations, and training to support and promote high quality clinical and translational research by qualified investigators.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Human Phenomic Science (CHPS) (RRID:SCR_022402) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/cear.html

Core aims to facilitate and build capacity for community based research and community engagement, while enhancing translation of research and technological developments to key public health and community stakeholders. Offers consultation on community engagement, training in participatory research methods, and assistance with development, implementation, and evaluation of community translation activities. Core is part of the Penn Institute for Translational Medicine and Therapeutics (ITMAT).

Proper citation: University of Pennsylvania Perelman School of Medicine Community Engagement and Research Core Facility (RRID:SCR_022408) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/tcmf/

Facility provides centralized service to efficiently produce genetically altered mice for basic research.� They include transgenic, chimeric and genome edited mice carrying transgenes or gene knockout and Knockin of specific interest.�Core also provides embryo and sperm cryopreservation as well as in vitro fertilization and re-derivation of live and cryopreserved lines, along with long-term storage of cryopreserved samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Transgenic and Chimeric Mouse Core Facility (RRID:SCR_022388) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/OCRCBioTrust/

Provides specimens including gynecologic cancer specimens such as fresh and frozen tissues, plasma, serum, peripheral blood mononuclear cells, blood, formalin fixed paraffin embedded (FFPE) samples, and Tissue Microarrays (TMAs). All samples collected have clinical annotation including demographic patient profiles, pathological and clinical notations, treatment history, and detail disease information, etc. We are building and maintaining centralized research database according to HIPPA specifications and Penn IRB standards.

Proper citation: University of Pennsylvania Perelman School of Medicine Ovarian Cancer Research Center Tumor BioTrust Collection Core Facility (RRID:SCR_022387) Copy   

•   Source: SciCrunch Registry