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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MRFSEQ
 
Resource Report
Resource Website
MRFSEQ (RRID:SCR_002972) algorithm resource, software resource Algorithm based on a Markov random field (MRF) model that uses additional gene coexpression data to enhance differential gene expression prediction power. It is able to call differentially expressed (DE) genes but also assign confidence scores to each inferred DE gene. markov, algorithm, gene expression, prediction algorithm, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at Riverside; California; USA
PMID:23793751 Free, Available for download, Freely available biotools:mrfseq, OMICS_01309 https://bio.tools/mrfseq SCR_002972 2026-02-15 09:18:25 0
IgBLAST
 
Resource Report
Resource Website
500+ mentions
IgBLAST (RRID:SCR_002873) software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on January 4,2023. IgBLAST was developed at NCBI to facilitate analysis of immunoglobulin V region sequences in GenBank. In addition to performing a regular BLAST search, IgBLAST has several additional functions: - Reports the germline V, D and J gene matches to the query sequence. - Annotates the immunoglobulin domains (FWR1 through FWR3). - Matches the returned hits (for databases other than germline genes) to the closest germline V genes, making it easier to identify related sequences. - Reveals the V(D)J junction details such as nucleotide homology between the ends of V(D)J segments and N nucleotide insertions. D and J gene reporting is only for nucleotide sequence search and requires a stretch of five or more nucleotide identity between the query and D or J genes. Sponsors: This resource is supported by the National Center for Biotechnology Information, a division of the U.S. National Library of Medicine. gene, analysis, domain, homology, immunoglobulin v, nucleotide, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: NCBI
PMID:23671333 Free, Freely available nif-0000-25554, biotools:igblast, OMICS_06083 https://bio.tools/igblast
https://sources.debian.org/src/ncbi-igblast/
SCR_002873 IgBLAST 2026-02-15 09:18:24 609
GoSurfer
 
Resource Report
Resource Website
1+ mentions
GoSurfer (RRID:SCR_005789) GoSurfer software application, software resource GoSurfer uses Gene Ontology (GO) information to analyze gene sets obtained from genome-wide computations or microarray analyses. GoSurfer is a graphical interactive data mining tool. It associates user input genes with GO terms and visualizes such GO terms as a hierarchical tree. Users can manipulate the tree output by various means, like setting heuristic thresholds or using statistical tests. Significantly important GO terms resulted from a statistical test can be highlighted. All related information are exportable either as texts or as graphics. Platform: Windows compatible gene, gene ontology, genome-wide, microarray, graph, data mining, statistical analysis, bioinformatics, genomics, gene cluster, multiple hypothesis testing, false discovery rate, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
has parent organization: Harvard T.H. Chan School of Public Health
PMID:15702958 Free for academic use biotools:gosurfer, nlx_149268 http://www.gosurfer.org
https://bio.tools/gosurfer
http://bioinformatics.bioen.illinois.edu/gosurfer/index.htm SCR_005789 2026-02-15 09:19:04 2
BOMP: beta-barrel Outer Membrane protein Predictor
 
Resource Report
Resource Website
1+ mentions
BOMP: beta-barrel Outer Membrane protein Predictor (RRID:SCR_007268) software application, software resource BOMP is a tool for prediction of beta-barrel integral outer membrane proteins. The user may submit a list of proteins, and receive a list of predicted BOMPs. The program, called the beta-barrel Outer Membrane protein Predictor (BOMP), is based on two separate components to recognize integral beta-barrel proteins. The first component is a C-terminal pattern typical of many integral beta-barrel proteins. The second component calculates an integral beta-barrel score of the sequence based on the extent to which the sequence contains stretches of amino acids typical of transmembrane -strands. To use the BOMP tool simply paste your fasta-formatted sequences into the text area, or choose a file which contains sequences. Then hit the submit button. It is possible to perform a BLAST search parallel with the predictions, which may be suitable in some cases. Using the BLAST search will however increase the running time substantially. Sponsors: This work was supported in part by grants from the Norwegian Research Council [SUP 140785/420 (GABI); FUGE/CBU151899/ISO], and the Meltzer Foundation, University of Bergen. Keywords: Beta-barrel, Membrane, Protein, Program, Software, Beta strand, Bacteria, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Bergen; Bergen; Norway
biotools:bomp, nif-0000-30236 https://bio.tools/bomp SCR_007268 BOMP Program 2026-02-15 09:19:23 5
VARSCAN
 
Resource Report
Resource Website
1000+ mentions
VARSCAN (RRID:SCR_006849) VarScan software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 7,2024. Platform-independent, technology-independent software tool for identifying SNPs and indels in massively parallel sequencing of individual and pooled samples. Given data for a single sample, VarScan identifies and filters germline variants based on read counts, base quality, and allele frequency. Given data for a tumor-normal pair, VarScan also determines the somatic status of each variant (Germline, Somatic, or LOH) by comparing read counts between samples. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, java, illumina, solid, life/pgm, roche/454, next-generation sequencing, variant, mutation caller, exome, whole-genome, snp, copy number alteration, somatic mutation, subclonal mutation, mutation, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Washington University in St. Louis; Missouri; USA
PMID:22300766
PMID:19542151
DOI:10.1101/gr.129684.111
THIS RESOURCE IS NO LONGER IN SERVICE , nlx_154687, biotools:varscan, OMICS_00094 http://varscan.sourceforge.net/
http://dkoboldt.github.io/varscan/
https://bio.tools/varscan
https://sources.debian.org/src/varscan/
http://genome.wustl.edu/software/varscan SCR_006849 Varscan2, VarScan - variant detection in massively parallel sequencing data, Varscan 2026-02-15 09:19:20 1769
LDSELECT
 
Resource Report
Resource Website
10+ mentions
LDSELECT (RRID:SCR_007010) LDSELECT software application, software resource Software program that analyzes patterns of linkage disequilibrium (LD) between polymorphic sites in a locus, and bins the SNPs on the basis of a threshold level of LD as measured by r2. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:ld_select, nlx_154426 https://bio.tools/ld_select SCR_007010 2026-02-15 09:19:21 15
PEDIGREEQUERY
 
Resource Report
Resource Website
1+ mentions
PEDIGREEQUERY (RRID:SCR_009041) PEDIGREEQUERY software application, software resource Software application that allows drawing pedigrees with a difficult structure, those containing consanguinity loops, and those individuals with multiple mates or several related families (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154007, biotools:pedcut https://bio.tools/pedcut SCR_009041 2026-02-15 09:20:02 1
FASTSLINK
 
Resource Report
Resource Website
10+ mentions
FASTSLINK (RRID:SCR_008664) FASTSLINK software application, software resource Software application that is a faster version of SLINK (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: SLINK
is related to: SUP
nlx_154312, biotools:snpcaller https://bio.tools/snpcaller SCR_008664 faster SLINK 2026-02-15 09:19:52 12
PEDPEEL
 
Resource Report
Resource Website
PEDPEEL (RRID:SCR_008436) PEDPEEL software application, software resource Software program that prepares pedigree data for calculation of Elston-Stewarts'' likelihood function. It finds an optimal way to peel a pedigree and returns text file containing 7 description arrays (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154524, biotools:pedpeel https://bio.tools/pedpeel SCR_008436 2026-02-15 09:19:49 0
ADMIXMAP
 
Resource Report
Resource Website
10+ mentions
ADMIXMAP (RRID:SCR_009035) ADMIXMAP software application, software resource General-purpose program for modelling admixture, using marker genotypes and trait data on a sample of individuals from an admixed population (such as African-Americans), where the markers have been chosen to have extreme differentials in allele frequencies between two or more of the ancestral populations between which admixture has occurred. The main difference between ADMIXMAP and classical programs for estimation of admixture such as ADMIX is that ADMIXMAP is based on a multilevel model for the distribution of individual admixture in the population and the stochastic variation of ancestry on hybrid chromosomes. This makes it possible to model the associations of ancestry between linked marker loci, and the association of a trait with individual admixture or with ancestry at a linked marker locus. (entry from Genetic Analysis Software) gene, genetic, genomic, c++, linux, ms-windows, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_153999, biotools:admixmap https://bio.tools/admixmap SCR_009035 Admixture mapping 2026-02-15 09:19:37 19
QGIS
 
Resource Report
Resource Website
100+ mentions
QGIS (RRID:SCR_018507) software application, software resource Open source cross platform desktop geographic information system application that supports viewing, editing, and analysis of geospatial data. Functions as geographic information system software, allowing users to analyze and edit spatial information, in addition to composing and exporting graphical maps. Geographic information system, viewing, editing, analysis, geospatial data, spatial information analysis, graphical map, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:QGIS https://bio.tools/QGIS SCR_018507 2026-02-15 09:22:14 400
asSeq
 
Resource Report
Resource Website
1+ mentions
asSeq (RRID:SCR_001625) asSeq software application, data processing software, data analysis software, source code, software resource Software that establishes a statistical framework for future developments of eQTL (expression quantitative trait locus) mapping methods using RNA-seq data (e.g., linkage-based eQTL mapping), and the joint study of multiple genetic markers and/or multiple genes. This R package has been submitted to R/bioconductor. It will be available on bioconductor soon. It is recommended to install this R package from bioconductor. You can also install this R package from the source code by yourself. Since the R package contains C code, a C complier is required for installation. With both R and appropriate c complier installed, this R package can be installed using the following command (in Mac Terminal window or Windows command window) R CMD INSTALL asSeq r, rna-seq, expression quantitative trait locus, total read count, allele-specific expression, allele-specific gene expression, gene expression quantitative trait locus, rna isoform, gene expression, genetic marker, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
PMID:21838806 Free, Available for download, Freely available OMICS_01948, nlx_153893, biotools:asseq https://bio.tools/asseq SCR_001625 2026-02-16 09:45:32 6
precrec
 
Resource Report
Resource Website
1+ mentions
precrec (RRID:SCR_018659) software application, software resource, data analytics software, software toolkit Software R package for fast and accurate precision recall and ROC curve calculations. Calculates accurate precision recall and Receiver Operator Characteristics curves. Precision recall, receiver operator characteristics, receiver operator characteristics curve, curve calculations, precision recall calculation, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CRAN
DOI:10.1093/bioinformatics/btw570 Free, Freely available biotools:precrec https://bio.tools/precrec SCR_018659 2026-02-16 09:49:30 1
STEPS
 
Resource Report
Resource Website
100+ mentions
STEPS (RRID:SCR_008742) STEPS software application, software resource, simulation software STEPS is a package for exact stochastic simulation of reaction-diffusion systems in realistic, complex 3D geometries. Our core simulation algorithm is an efficient implementation of a variation on Gillespie''s SSA, extended to deal with diffusion of molecules over the elements of a 3D tetrahedral mesh. While it was mainly developed for simulating detailed models of neuronal signaling pathways in dendrites and around synapses, it is a general tool and can be used for studying any biochemical pathway in which spatial gradients and morphology are thought to play a role. We have implemented STEPS as a set of Python modules, which means STEPS users can use Python scripts to control all aspects of setting up the model, generating a mesh, controlling the simulation and generating and analyzing output. The core computational routines are still implemented as C/C++ extension modules for maximal speed of execution. reaction-diffusion, stochastic, signaling, molecular, python, software, simulator, reaction kinetics, 3d diffusion, signaling pathway, scripting, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Okinawa Institute of Science and Technology
has parent organization: University of Antwerp; Antwerp; Belgium
GOA ;
UA Belgium ;
Human Frontier Science Program ;
Okinawa Institute of Science and Technology
biotools:steps, nlx_143852 https://bio.tools/steps http://steps.sourceforge.net/STEPS/Home.html SCR_008742 STochastic Engine For Pathway Simulation 2026-02-16 09:47:15 336
ML Repo
 
Resource Report
Resource Website
1+ mentions
ML Repo (RRID:SCR_017079) MLRepo service resource, data repository, storage service resource Machine learning repository for microbiome datasets. machine, learning, repository, microbiome, dataset, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:ML_Repo https://bio.tools/ML_Repo SCR_017079 Machine Learning Repository 2026-02-16 09:49:09 2
Human Neocortical Neurosolver
 
Resource Report
Resource Website
10+ mentions
Human Neocortical Neurosolver (RRID:SCR_017437) HNN software application, data processing software, data analysis software, software resource, simulation software Open source software package for circuit level interpretation of human EEG/MEG data. Software tool for interpreting cellular and network origin of human MEG/EEG data. Simulates electrical activity of neocortical cells and circuits that generate primary electrical currents underlying EEG/MEG recordings. Designed for researchers and clinicians, without computational neural modeling experience, to develop and test hypothesis on circuit origin of their data. Neural, modeling, human, imaging, data, EEG, MEG, electrical, neocortical, cell, circuit, BRAIN Initiative, bio.tools is recommended by: BRAIN Initiative
is listed by: Debian
is listed by: bio.tools
has parent organization: Brown University; Rhode Island; USA
has parent organization: Yale University; Connecticut; USA
has parent organization: Massachusetts General Hospital
NIBIB R01 EB022889;
NIDCD R01 DC012947
DOI:10.1101/740597 Free, Available for download, Freely available SCR_017678, biotools:HNN https://github.com/jonescompneurolab/hnn
https://github.com/jonescompneurolab/hnn/tree/0.0.5
https://github.com/jonescompneurolab/hnn/tree/0.1.2
https://zenodo.org/record/2394296#.Xg4rCEdKiM9
https://bio.tools/HNN
SCR_017437 2026-02-16 09:49:14 13
PLANTTFDB
 
Resource Report
Resource Website
1000+ mentions
PLANTTFDB (RRID:SCR_003362) PlantTFDB data or information resource, production service resource, analysis service resource, database, service resource, data analysis service Comprehensive plant transcription factor database. Interface to allow users to search the database by IDs or free texts, to make sequence similarity search against TFs of all or individual species, and to download TF sequences for local analysis.PlantTFDB 3.0: a portal for the functional and evolutionary study of plant transcription factors transcription factor, expression, regulation, interaction, conserved element, phenotype, function, evolution, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Database of Poplar Transcription Factors
is related to: Plant Ontology
has parent organization: Peking University; Beijing; China
China 863 ;
China 973 ;
NSFC ;
China NSFC
PMID:24174544
PMID:17933783
PMID:21097470
Free, Available for download, Freely available nif-0000-03311, biotools:planttfdb_2.0, OMICS_00560, r3d100010137 https://bio.tools/planttfdb_2.0
https://doi.org/10.17616/R3JG6V
http://planttfdb.cbi.pku.edu.cn SCR_003362 , PlantTFDB 2.0, Plant Transcription Factor Database 2026-02-17 10:00:17 1109
genomation
 
Resource Report
Resource Website
50+ mentions
genomation (RRID:SCR_003435) genomation software application, data processing software, data analysis software, software resource, software toolkit Software R package for simplfiying common tasks in genomic feature analysis. Toolkit to summarize, annotate and visualize genomic intervals. Provides functions for reading BED and GFF files as GRanges objects, summarizing genomic features over predefined windows so users can make average enrichment of features over defined regions or produce heatmaps. Can annotate given regions with other genomic features such as exons,introns and promoters. genome, genomic interval, genomic feature analysis, GRanges objects, annotate given regions, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:25417204 Free, Available for download, Freely available biotools:genomation, OMICS_02306 https://github.com/al2na/genomation
https://github.com/BIMSBbioinfo/genomation
https://bio.tools/genomation
http://al2na.github.io/genomation/ SCR_003435 2026-02-17 10:00:00 58
NeuroMatic
 
Resource Report
Resource Website
100+ mentions
NeuroMatic (RRID:SCR_004186) data analysis software, software application, data processing software, software resource NeuroMatic is a collection of Igor Pro functions for analyzing electrophysiological data. By allowing users to organize their data into Sets and Groups, NeuroMatic makes it relatively easy to compute transformations and statistical analyses on their data, including scaling, alignment averaging, baseline subtraction, spike detection, stationarity analysis, rise-time computations, etc. Being open source and modular designed, NeuroMatic also allows users to develop their own analysis functions that can be easily incorporated into NeuroMatic's framework. Note, if you have reached this page in search of a freeware tool for neuronal reconstructions, you are more likely to be interested in Neuromantic, a software package that sounds like NeuroMatic, but is not quite the same. Features of NeuroMatic Include * Sorting, Scaling, Averaging, Interpolation * Max / Min / Mean / Level / Rise Time / FWHM / Slope Measurements * Stability / Stationarity Analysis * Event Detection * Waveform Template Matching * Spike Raster Plots * Interspike-Interval and Peri-Stimulus Time (PST) Histograms * Compact Easy-to-Use Interface * Modular design as a basis for your own procedures * Extra space for your own buttons and controls * Import functions for Axograph and Pclamp data * Automatic macro generation for batch processing Supporting Agencies: MRC, Wellcome Trust Spike, Event, Fit, NClamp, Acquisition, spike train, EPSP, IPSP, IPSC, EPSC epsc, epsp, event, fit, acquisition, data management, ipsc, ipsp, nclamp, software, spike, spike train, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University College London; London; United Kingdom
PMID:29670519 nif-0000-00073, biotools:neuromatic https://bio.tools/neuromatic SCR_004186 NeuroMatic 2026-02-17 10:00:25 301
RatMine
 
Resource Report
Resource Website
1+ mentions
RatMine (RRID:SCR_004190) data access protocol, data or information resource, production service resource, analysis service resource, database, service resource, software resource, web service, data analysis service RatMine integrates data from RGD, UniProtKB, NCBI, KEGG and other sources to form a web-based data warehouse and tool set tailored for rat based data research. Search RatMine by entering names, identifiers, or keywords for genes, proteins, pathways, papers, etc. Additionally, we support programmatic access to our data through Application Programming Interface - choose from Perl or Java API. RatMine is a data warehouse that integrates many diverse biological data sets. The main focus is R. norvegicus genomics and proteomics. By integrating such data into one place it is possible to construct queries across domains of biological knowledge. The RatMine user interface is designed to go beyond simply looking up an identifier and viewing a report page. Some of the features include: * Quick Search is available just like on other sites, type in an identifier to see a report page. * Template queries are ''canned'' queries that provide a simple form to perform a specific task. You can create your own templates if you log in. * Lists lets you operate on whole lists of data at once. You can upload lists or save them from results tables. We also create useful public lists for everyone to use. * MyMine lets you create an account to save your own queries, bags and templates, as well as marking public templates as favorites. disease, interaction, proteins, single nucleotide, gene ontology, mammalian phenotype, publication, genomics, pathway, quantitative trait loci, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Medical College of Wisconsin; Wisconsin; USA
biotools:RatMine, nlx_21635 https://bio.tools/RatMine SCR_004190 2026-02-17 10:00:11 5

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