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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core facilitates access, generation, and usage of novel in vitro mouse and human organoid systems to promote innovative basic and translational research and disease modeling. Provides expertise in genome editing technologies for targeted knock outs, point mutations, and reporter generation in organoid systems. Provides many specialized medias and reagents to support most common organoid culture systems.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Organoid and Tissue Modeling Shared Resource Core Facility (RRID:SCR_021993) Copy
Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.
Proper citation: State University of Campinas Multidisciplinary Center for Biological Investigantion on Laboratory Animals Science Core Facility (RRID:SCR_022203) Copy
https://vtpb.tamu.edu/flow-cytometry/
Provides flow cytometry experimental design, data collection, data analysis and cell sorting services; training for flow cytometers, imaging flow cytometer, and data analysis using IDEAS and FlowJo software;staff assisted flow cytometry and imaging flow cytometry data acquisition, cell sorting, and data analysis, experimental design and consultation services. FCF currently has Beckman Coulter Moflo Astrios cell sorter, Luminex/Amnis Image Stream X Mark II, Luminex/Amnis Cell Stream, and Becton Dickinson Accuri C6 flow cytometer. Astrios cell sorter is housed in ClassII BSC and has 3 lasers (405nm, 488nm, 642nm) and 11 detectors and can sort up to 6 populations simultaneously. Image Stream X Mark II is equipped with 20x, 40x, 60x objectives, 4 lasers (405nm, 488nm, 561nm, 642nm), 10 detection channels, EV mode for small particle detection, and an autosampler.Cell Stream is equipped with 3 lasers (405nm, 488nm, 642nm), 13 detection channels, EV mode for small particle detection, and autosampler. Accuri C6 is equipped with 2 lasers (488nm, 642nm), and 4 detection channels.
Proper citation: Texas A and M University College of Veterinary Medicine and Biomedical Sciences Flow Cytometry Core Facility (RRID:SCR_022169) Copy
Core provides access to instrumentation essential for studies of surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. Core provides training to students and faculty on instrumentation as well as consolation of measurements needs and data interpretation, supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.Supports collaborative research projects with outside industrial users.
Proper citation: Texas A and M University Materials Characterization Core Facility (RRID:SCR_022202) Copy
https://asrc.gc.cuny.edu/neuroscience/facilities/epigenetics-core-facility/
Facility at Advanced Science Research Center of City University of New York provides research resources and services that include nucleic acid extraction and fragmentation, quantitative gene expression analysis, targeted DNA methylation analysis in specific genomic loci of interest, next generation sequencing RNA-seq and ChIP-seq, and single cell genomics.Provides advanced cell sorter with biosafety protection for flow cytometry service, services for RNAScope to allow for in situ hybridization detection of transcriptional targets with spatial resolution.
Proper citation: City University of New York Advanced Science Research Center Epigenetics Core Facility (RRID:SCR_021914) Copy
https://sars-cov-2.creative-biolabs.com/
Core helps to carry out analysis and research on SARS-COV2 virus. Provides COVID-19/ SARS-COV2/ 2019-nCoV Research Tools and Services.Team has developed related proteins, antibodies, nucleic acid extraction kits and other products to help researchers quickly develop effective anti-COVID-19 drugs and vaccines.Provides preclinical research services, various in vivo and in vivo research models, and in vivo diagnostic immunoassay services.
Proper citation: SARS Creative Biolabs Core Facility (RRID:SCR_021772) Copy
https://www.uab.edu/cores/ircp/bds
Core offers access to computational biology capabilities. Provide services, foster long term collaborations with UAB research community, and provide training for biomedical investigators on specific set of analysis tools and techniques.Places special emphasis in areas of genomics, transcriptomics, systems biology and translational medicine. Services include data analysis, biological interpretation, grant assistance, and training.
Proper citation: University of Alabama at Birmingham Biological Data Science Core (RRID:SCR_021766) Copy
https://www.creative-biolabs.com/
Custom service provider that has extensive experience in various antibody production and engineering fields.Services includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies (including phage display, bacterial display and yeast display).Conducting in depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches.OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG, and IgG, are also available at the most competitive price in industry.
Proper citation: Creative Biolabs Core Facility (RRID:SCR_021767) Copy
https://www.uniklinik-freiburg.de/mr-en/mrdac.html
Core is registered in resources database of German Research Foundation under number RI_00444. Center origins in Medical Physics group, Dept. of Radiology, University Medical Center Freiburg, one of leading group in field of methodological developments in Magnetic Resonance Imaging and Spectroscopy and its application in clinics and research.Serves as platform for collaborations with partners in industry and research according to industrial quality and performance standards. Main branches of MRDAC include development of novel MR sequences and methods and design, implementation, and execution of pharmaceutical MR studies.Offers services such as teaching, training, and consulting.
Proper citation: University of Freiburg Magnetic Resonance Development and Application Center Core Facility (RRID:SCR_021926) Copy
http://voices.uchicago.edu/animalresources
Core assists investigators in performing their animal research while ensuring appropriate and humane care of all laboratory animals.
Proper citation: University of Chicago Animal Resources Center Core Facility (RRID:SCR_021806) Copy
https://sites.google.com/ucsc.edu/pal/
Core facility provides Thermo Element XR high-resolution ICPMS,Thermo X-Series II quadrupole ICPMS,Thermo iCap 7400 ICP-OES, Photon Machines Analyte 193H excimer laser system, and Zygo NewView Element XR7200 Vertical Scanning Interferometer for depth profiling and analysis of laser pit morphology.
Proper citation: University of California at Santa Cruz Plasma Analytical Laboratory Core Facility (RRID:SCR_021925) Copy
https://genetics.med.upenn.edu/cores/cell-center-services/
Facility provides basic cell culture training and services in various cell culture and related procedures e.g. Mycoplasma and Endotoxin testing. Services include cell culture at various scales, expansion of primary cells, seed cell cultures from on site cell bank, cell storage; large scale growth of hybridoma and other cell lines followed by antibody purification by protein G column or recombinant protein production; EBV induced transformation of lymphocytes.Offers hybridoma generation by cell fusion and screening and, transfection of mammalian cells. Facility prepares specialized cell culture media, Drosophila media and, various tissue culture and molecular biological reagents.
Proper citation: University of Pennsylvania Perelman School of Medicine Cell Center Services Core Facility (RRID:SCR_022391) Copy
https://www.itmat.upenn.edu/cnsc/
Provides expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, nanoparticle production and surface functionalization, and site-specific antibody labeling. Our chemists provide custom, problem specific support for researchers in medical, chemical, and materials science fields. Specific services include consultation and assistance with the design of chemical/medicinal compounds, in house synthesis of chemical/medicinal compounds, custom nanoparticle design and synthesis, custom nanoparticle surface functionalization, polymer and dendrimer synthesis, and site specific antibody labeling.
Proper citation: University of Pennsylvania Perelman School of Medicine Chemical and Nanoparticle Synthesis Core Facility (RRID:SCR_022390) Copy
https://wiki.umontreal.ca/spaces/plateformes/pages/189568061/Core+Facilities+-+CI2B
Offers instruments and services to support research in microscopy.
Proper citation: University of Montreal BioImaging Platform Core Facility (RRID:SCR_022311) Copy
Provides services in disciplines of genomics, microbiology and immunology. We engage in collaborative projects that benefit from close interactions with veterinarians and human clinicians alike.
Proper citation: University of Pennsylvania School of Veterinary Medicine Center for Host Microbial Interactions Core Facility (RRID:SCR_022310) Copy
https://www.med.upenn.edu/camris/
Center for Advanced Magnetic Resonance Imaging and Spectroscopy (CAMRIS) is a Radiology research core at the University of Pennsylvania’s Perelman School of Medicine providing oversight in the responsible use and application of Magnetic Resonance (MR) in research at Penn. CAMRIS oversees eight state-of-the-art whole-body MR scanners and provides scanning services by experienced technologists to a diverse community of investigators conducting innovative human and animal research.
Proper citation: University of Pennsylvania Center for Advanced Magnetic Resonance Imaging and Spectroscopy Core Facility (RRID:SCR_022398) Copy
https://www.med.upenn.edu/cbica/
Offers development and application of advanced computational and analytical techniques that quantify morphology and function from biomedical images, as well as on relating imaging phenotypes to genetic and molecular characterizations, and on integrating this information into diagnostic and predictive tools in era of personalized medicine. Computational methods can contribute significantly to automated, reproducible and quantitative interpretations of biomedical images. Translates advanced computational and analytical imaging methods to clinic, by providing forum in which interactions between researchers and clinicians facilitate bidirectional flow of ideas, algorithms and data between laboratory and clinic.
Proper citation: University of Pennsylvania Perelman School of Medicine Center for Biomedical Image Computing and Analytics Core Facility (RRID:SCR_022397) Copy
https://www.med.upenn.edu/CAMIPM/
Core dedicated to development and application of innovative, novel magnetic resonance and optical imaging techniques. Provides research and computing resources for projects with focus on developing instrumentation, methodologies, and data analysis techniques for quantitative assessment of functional, structural, and metabolic parameters in humans with use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques.
Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Metabolic Imaging in Precision Medicine Core Facility (RRID:SCR_022396) Copy
Provides infrastructure support for research on human cognition, perception, affect, disordered cognition, and extension to preclinical models. By consolidating methodological expertise in these domain areas as services, center seeks to facilitate cutting edge research using largely shared set of methods and tools for elucidating brain behavior relationships in health and disease.
Proper citation: University of Pennsylvania Perelman School of Medicine Brain Science Service Center Core Facility (RRID:SCR_022394) Copy
https://www.med.upenn.edu/idom/drc/cores/rodent.html
Core (RMPC, formerly MPPMC) is metabolic core. Offers technology and phenotyping services to allow investigators to study metabolism in pre-clinical rodent models. Services include measurements of body composition (fat and lean mass) using NMR and DEXA, energy balance (food intake, locomotor activity, energy expenditure) using indirect calorimetry in either Columbus Instruments CLAMS system or Sable Systems Promethion System (with optional gas analyzer), and other in vivo metabolic phenotyping services (glucose clamps, insulin and glucose tolerance tests, telemetric monitoring of blood glucose or blood pressure, bomb calorimetry).
Proper citation: University of Pennsylvania Perelman School of Medicine Rodent Metabolic Phenotyping Core Facility (RRID:SCR_022427) Copy
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