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https://hpc.ncsu.edu/main.php

Core, available through NC State Office of Information Technology, provides entry and intermediate level computing resources and consulting support for research and instruction.

Proper citation: North Carolina State University High Performance Computing Services Core Facility (RRID:SCR_022168) Copy   

•   Source: SciCrunch Registry

https://vetmed.tamu.edu/cvm-histology-lab/research-histology-unit/

Provides histology (including cryosectioning, IHC and IFC) digital pathology and veterinary pathology (board certified veterinary pathologist on staff) services.

Proper citation: Texas A and M University Veterinary Medicine and Biomedical Sciences Research Histology Unit Core Facility (RRID:SCR_022201) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/population-health

Core supports access to and expertise in data management, analyses, and mapping and data visualization of population based databases. These databases are ideal for studies requiring access to large samples of patients and/or providers; examination of trends in treatment, screening, or other healthcare services; impact of policy changes or recommendations on healthcare services; investigating dissemination of evidence based technologies and interventions; disparities of treatment or other health care services between groups; geographic distributions of cancer patients and relationships with other geospatial data.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Population Health Shared Resource Core Facility (RRID:SCR_021992) Copy   

•   Source: SciCrunch Registry

https://ibt.tamu.edu/cores/protein-production-core/index.html

Core provides cloning, expression and purification services of functional proteins at scale that meets the quantity and purity benchmarks for structural, biophysical, biochemical, and therapeutics studies; characterizes macromolecular biophysics and interaction energetics using instrumentation and techniques that can analyze association and kinetic binding constants by surface plasmon resonance, enthalpies and entropies of binding by isothermal titration calorimetry, as well as determination of stoichiometry, stability, and homogeneity by both techniques.

Proper citation: Texas A and M Health Science Center IBT Protein Production, Characterization and Molecular Interaction Core Facility (RRID:SCR_022200) Copy   

•   Source: SciCrunch Registry

https://microbiome.forsyth.org/

Offers Next Generation Sequencing (NGS) and comprehensive data analyses and interpretation for 16S rRNA gene amplicon sequences and other big data sequence applications. Offers analyses of previously obtained sequences. Many investigators are familiar with Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) as well as its predecessor the Human Oral Microbe Identification Microarray (HOMIM) for rapid 16S rDNA analyses of oral clinical samples. We continue in that tradition using bioinformatic methodology, which will provide the best possible taxa identification.

Proper citation: Forsyth Institute Oral Microbiome Core Facility (RRID:SCR_022166) Copy   

•   Source: SciCrunch Registry

https://www.cshl.edu/research/cancer/flow-cytometry/

Resource provides equipment, training, and operating assistance for cell sorting and analysis. Facility staff oversees equipment maintenance, trains new users, and assists with assay development and operation of equipment.

Proper citation: Cold Spring Harbor Laboratory Flow Cytometry Shared Resource Core Facility (RRID:SCR_022164) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/pathology/biobanking-services

Biorepository Section provides services to support biobanking, clinical trials, and research studies. Provides access to patient specimens collected from clinical and research procedures that are handled, processed, analyzed, and interpreted in uniform manner. Services include, collection, processing, storage, clinicopathological annotation, and distribution of biospecimens.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Biorepository Core Facility (RRID:SCR_021989) Copy   

•   Source: SciCrunch Registry

https://cu.corefacilities.org/service_center/show_external/5637/drug_discovery_and_development_shared_resource

Provides expertise and infrastructure to facilitate drug discovery at different stages of development pipeline, including assay development and validation, high throughput screening and image based high content screening discovery, validation and optimization, and in vitro and in vivo pharmacology including pharmacokinetics and pharmacodynamics as well as toxicology.Sign in to iLab using University of Colorado credentials.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Drug Discovery and Development Shared Resource Core Facility (RRID:SCR_021986) Copy   

•   Source: SciCrunch Registry

http://functionalgenomicsfacility.org/

Core facilitates access to tools including shRNA, ORF, CRISPR to investigate gene function on genome wide scale. Provides protocols and expertise for use of these genomics tools. Serves as forum for scientific exchange and discussion in the field of functional genomics.Sign in to iLab using University of Colorado credentials.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Functional Genomics Core Facility (RRID:SCR_021987) Copy   

•   Source: SciCrunch Registry

https://psxl.ku.edu/

Core laboratory with infrastructure and expertise to perform all aspects of protein and small molecule structure determination using X-ray crystallography. For protein structure determination, high-throughput methods are utilized to move projects rapidly from gene-to-structure.

Proper citation: University of Kansas Lawrence Protein Structure and X-ray Crystallography Laboratory Core Facility (RRID:SCR_021742) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/genomics

GSR provides genome-wide analyses of DNA sequence, transcriptomes, epigenetics and cytogenomics using next generation sequencing (NGS) and gene microarrays; and single cell genomic and transcriptomic analyses including single cell immune profiling and spatial gene expression.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Genomics Shared Resource Core Facility (RRID:SCR_021984) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/proteomics-metabolomics-facility

Facility provides diverse range of Mass Spectrometry based proteomics and metabolomics services.Services include sample preparation, sample analysis, and data interpretation.

Proper citation: Cornell University BRC Proteomics and Metabolomics Core Facility (RRID:SCR_021743) Copy   

•   Source: SciCrunch Registry

https://emcore.ucsd.edu/

UCSD Cellular and Molecular Medicine Electron Microscopy core provides services in sample preparation and imaging by Transmission Electron Microscopy and Correlative Light and Electron Microscopy.

Proper citation: University of California at San Diego Electron Microscopy Core Facility (RRID:SCR_022039) Copy   

•   Source: SciCrunch Registry

https://www.ed.ac.uk/clinical-research-facility/core-services/mass-spectrometry

Core is part of Edinburgh Clinical Research Facility, situated in the Centre for Cardiovascular Sciences in the Queen's Medical Research Institute. We train and host undergraduate students, PhD and post-doctoral students in practical skills and mass spectrometry operation. We have expertise in sample preparation, separation and mass spectrometry analysis for targeted small molecule analysis in clinical and pre-clinical studies. We operate under Good Clinical Practice for laboratories for clinical studies. Steroids, drugs and endogenous molecules and metabolic pathways in plasma, serum, tissue. We also have Imaging Mass spectrometry capabilities with a Waters Synapt G2Si, MALDI and DESI.

Proper citation: University of Edinburgh Clinical Research Mass Spectrometry Core Facility (RRID:SCR_021833) Copy   

•   Source: SciCrunch Registry

https://microscopy.tamu.edu/

Core with expertise in Transmission Electron Microscopy, Scanning Electron Microscopy, Light Microscopy, and supporting instruments. Staff members provide quality training and education through sessions, short courses, formal courses, open house seminars, and more.

Proper citation: Texas A and M University Microscopy and Imaging Center Core Facility (RRID:SCR_022128) Copy   

•   Source: SciCrunch Registry

https://statlab.colostate.edu/

Core facility that provides statistical expertise for benefit of advancing quality of scientific research and education at CSU and beyond, while educating next generation of applied statisticians.

Proper citation: Colorado State University Graybill Statistics and Data Science Laboratory Core Facility (RRID:SCR_022005) Copy   

•   Source: SciCrunch Registry

https://iriss.colostate.edu/

Core facility that provides social science research expertise and resources for design, collection, management, analysis, and dissemination of original social science data, including interviews, focus groups, surveys, photo voice, social network analysis, program evaluation, team assessments, and mixed method studies.

Proper citation: Colorado State University Institute for Research in the Social Sciences Core Facility (RRID:SCR_022004) Copy   

•   Source: SciCrunch Registry

https://www.chla.org/research/cellular-imaging-core

Core provides equipment in microscopy and digital imaging. Primary focus is technology transfer and provision of facilities for acquisition and analysis of histological and cytological preparations. Provides training in the use of imaging instrumentation and in the application of image analysis procedures for generation of quantitative data.

Proper citation: University of Southern California CHLA Cellular Imaging Core Facility (RRID:SCR_021964) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/bms/

Proteomics and Metabolomics services and collaborative efforts are provided at Biological Mass Spectrometry Facility. We use high resolution Orbitrap mass spectrometers with UPLC at high flow for metabolomics and nanoUPLC for proteomics work. We have Bruker Autoflex for self service MALDI. Our proteomics services are protein ID, quantitation, and modification analysis, with fractionation for deeper coverage and de novo sequencing of mAbs available. We collaborate for customized projects. We have untargeted metabolomics for quantitative or qualitative analysis of extracted metabolites using C18 column.

Proper citation: University of Texas at Austin Biological Mass Spectrometry Proteomics Core Facility (RRID:SCR_021728) Copy   

•   Source: SciCrunch Registry

https://www.stowers.org/technology/genome-engineering

Core supports genome engineering using CRISPR technology. Provide services to generate knockouts, insertions, deletions, and point mutations in various organisms. Services for genome engineering include guideRNA design, homology-directed repair template design, production of modified mammalian cell lines, preparation of reagents for delivery to embryos, and mutation detection by targeted deep sequencing. Pooled screening is also coordinated and supported by our team.We acquire, prepare, and validate pooled libraries as an Institute resource. In coordination of our pooled screen workflow, we work with other teams to track the progress of these projects. Once resulting cell populations from the screen are delivered, our team does genomic DNA purification, target amplification, and preparation for NGS. We now offer a TAIL-PCR service to identify the location of random integration events. We have successfully identified locations in killifish, fly, zebrafish, and sea anemone.Team is responsible for maintaining and distributing clone and vector collections for the Institute.

Proper citation: Stowers Institute for Medical Research Genome Engineering Core Facility (RRID:SCR_021729) Copy   

•   Source: SciCrunch Registry