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https://medicine.iu.edu/research/support/service-cores/chemical-genomics

Core provides collection of diversity-oriented, drug-like, and natural small molecules in non-redundant libraries, variety of automated liquid handling and assay detection systems such as EnVision Multiplate reader and ArrayScan HCA System, modern equipment for medicinal and analytical chemistry including NMR, LC-QTOF MS, HPLC, Peptide Synthesizer, and sophisticated chemoinformatics tools. Besides traditional high-throughput screening and hit compound optimization services, newly adapted technologies include arrayed CRISPR screening, phage display, and SAR by NMR.

Proper citation: Indiana University School of Medicine Chemical Genomics Core Facility (RRID:SCR_018785) Copy   

•   Source: SciCrunch Registry

http://www.pasteur.fr/biophysics

Provides services and instrumentation for characterization of biological macromolecules with technical and methodological expertise. Provides characterization of macromolecules including shape, folding, stability auto-association,and they interactions including stoichiometry,thermodynamic and kinetic parameters.

Proper citation: Pasteur Institute Biophysics of Macromolecules and their Interactions Core Facility (RRID:SCR_018267) Copy   

•   Source: SciCrunch Registry

https://www.research.uky.edu/pathology-core

Core facilitates COCVD projects by providing equipment and technical expertise to paraffin-embed and section tissue specimens and perform chemical staining of tissue sections to be examined, photographed and analyzed chromogenically by light microscopy.Training in immunohistochemical staining is available.

Proper citation: University of Kentucky College of Medicine, Lexington, Pathology Research Core Facility (RRID:SCR_018824) Copy   

•   Source: SciCrunch Registry

https://grcf.jhmi.edu/

Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.

Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy   

•   Source: SciCrunch Registry

https://animalcare.umich.edu/business-services/ulam-pathology-core/

Our core is affiliated with the Unit for Laboratory Animal Medicine (ULAM) at the University of Michigan-Ann Arbor. We provide animal pathology services in support of non-GLP preclinical, translational, or basic science studies. Services include histology preparation, immunohistochemistry, animal hematology and serum chemistry assays, digital slide scanning/image analysis, and pathology interpretation by board-certified veterinary pathologists. Our core mission is to reduce bias and increase rigor within non-GLP animal research by providing high quality, documented, pathology support that may not be otherwise accessible within individual laboratories. Our laboratory maintains internal SOPs, documented quality control practices, and accountability/chain-of-custody records for all submissions. Additionally, we participate in an external quality control program through the Veterinary Laboratory Association.

Proper citation: University of Michigan ULAM Pathology Core Facility (RRID:SCR_018823) Copy   

•   Source: SciCrunch Registry

https://childrenshospital.corefacilities.org/service_center/show_external/3145

Core with advanced instrumentation in Light and Electron Microscopy.Core provides confocal, multiphoton microscopy,electron microscopy,image analysis.

Proper citation: Harvard Medical School PCMM Microscopy Core Facility (RRID:SCR_018822) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/center-biospecimen-research-development

Assists researchers and clinicians with molecular and morphologic characterization of normal and disease tissues of interest in support of biomarker discovery and translational research. Offers both routine and advanced histology immunohistochemistry, in situ and whole slide scanning services.

Proper citation: New York University School of Medicine Center for Biospecimen Research and Development Histology Core Facility (RRID:SCR_018304) Copy   

•   Source: SciCrunch Registry

https://vbrn.org/proteomics-services/

Provides central resource of mass spectrometry based proteomics technologies to identify, characterize and quantify target proteins in various biological and biomedical samples. Provides mass spectrometry expertise for analyzing proteins and peptides for proteomics studies, support for data analysis from proteomics measurements, training in proteomics methods, and experimental design.

Proper citation: Vermont University Proteomics Core Facility (RRID:SCR_018667) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lmcf/

Provides access to instruments and training. Instruments including Dell Precision 7910 Analysis PC,Leica DMRXA Upright Widefield Microscope, Nikon E600 Upright Widefield Microscope, Nikon N-SIM structured illumination super-resolution and A1 laser scanning confocal microscope, Nikon Inverted Spinning Disk Confocal Microscope, Zeiss 510 Laser Scanning Confocal Microscope.

Proper citation: Colorado University at Boulder Light Microscopy Core Facility (RRID:SCR_018993) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/mcc

Core helps researchers investigate interactions between small molecules and biological systems by providing medicinal chemistry and chemical biology expertise and organic synthesis support.

Proper citation: Oregon Health and Science University Medicinal Chemistry Core Facility (RRID:SCR_019048) Copy   

•   Source: SciCrunch Registry

https://www.danforthcenter.org/our-work/core-facilities/phenotyping/

Core provides instruments including Scanalyzer 3D platform which consists of multiple digital imaging chambers connected to controlled environment Conviron growth house by conveyor belt system, resulting in continuous imaging loop and enables repeatedly image plants at multiple points throughout time.RGB imaging allows visualization and quantification of plant color and structural morphology. Near-infrared (NIR) enables visualization and quantification of plant water-use efficiency.Watering and weighing stations are customizable to deliver water and nutrients on specified schedule by volume or weight. Standard phenotyping services include operation and maintenance of LemnaTec Scanalyzer system, as well as technical support and troubleshooting.

Proper citation: Donald Danforth Plant Science Center Phenotyping Core Facility (RRID:SCR_019049) Copy   

•   Source: SciCrunch Registry

http://www.dartmouth.edu/~dartlab/

Offers services in customized end point assays using human WB/PBMCs for clinical trials, ELISPOT, multiplex cytokine analysis, cell energy analysis, blood processing and cryopreservation,up to 20 color flow cytometry phenotyping and up to 11color FACS cell subset sorting. Provides consultation, data analysis, and Flow Cytometry training course.

Proper citation: Dartmouth Geisel School of Medicine Immunoassay and Flow Cytometry Core Facility (RRID:SCR_019165) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/core-facilities/intermountain-neuroimaging-consortium

Magnetic resonance imaging research facility. Provides Tesla Siemens MAGNETOM Prismafit MRI scanner, located at Center for Innovation and Creativity (CINC) on CU Boulder campus.

Proper citation: Colorado University at Boulder Intermountain Neuroimaging Consortium Core Facility (RRID:SCR_018990) Copy   

•   Source: SciCrunch Registry

https://umassmed.edu/research/cores/mediaprep/

Provides custom made microbiological media for bacteria,yeast,C.elegans,Chlamydamonas research in liquid and agar forms. Common lab buffers and solutions are also available.

Proper citation: UMass Medical School Media Prep Core Facility (RRID:SCR_019167) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/massspec/

Offers analytical and instructional expertise in mass spectrometry with practical training and access to instrumentation.Located in room C1B90 of Jennie Smoly Caruthers Biotechnology Building houses six mass spectrometry systems.Instruments are interfaced with chromatographic system in order to separate complex mixture samples. Offers training for open access to some instruments including Thermo ISO LT GCMS, Synapt G2 HDMS, Agilent 6120 LCMS, and 4000 Q-trap QQQ instruments.

Proper citation: Colorado University at Boulder Central Analytical Mass Spectrometry Core Facility (RRID:SCR_018992) Copy   

•   Source: SciCrunch Registry

https://brcf.medicine.umich.edu/cores/bioinformatics-core/

Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.

Proper citation: University of Michigan Medical School Bioinformatics Core (RRID:SCR_019168) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/flowcytometry/

Core provides flow cytometry services to UNCCH research community as well as to others in Research Triangle Park area.Provides help with experimental design, sample acquisition, data analysis, and sorting, training to run analyzers independently at reduced cost, guidance about rigor and reproducibility in all aspects of experimental design, data acquisition, analysis and reporting.

Proper citation: University of North Carolina at Chapel Hill Flow Cytometry Core Facility (RRID:SCR_019170) Copy   

•   Source: SciCrunch Registry

https://transgenic.uchicago.edu

Provides investigators with genetically manipulated mice through transgenic technology or embryonic stem cell manipulation. Provides fully operational construction and gene targeting service. Offers annual course in Mouse Handling and Breeding. Provides transgenic plasmid and BAC, CRISPR and TARGATT injections, ES Cell targeting, screening, culture and blastocyst injections, rederivation, breeding and mouse services and consultation on project development.

Proper citation: University of Chicago Transgenic and ES Cell Technology Mouse Core Facility (RRID:SCR_019171) Copy   

•   Source: SciCrunch Registry

https://dentistry.musc.edu/research/gcohr

Core offers investigators opportunity to address research questions that require use of gnotobiotic animals. Standard services provide germ free mice (e.g. BALB/c, C57BL/6), deriving new strains of mice into germ free state by caesarean section, tissue collection and/or fluid from mice that have not received treatment or manipulations, exporting germ free mice in sterile transporters to other institutions. Non-Standard Services include maintaining and breeding newly derived germ free mice, administration of specialized diets, administration of compounds as therapeutic or disease-inducing agents, tissue collection and/or fluid from mice that have received treatment or manipulations.

Proper citation: Medical University of South Carolina College of Dental Medicine Gnotobiotic Animal Core Facility (RRID:SCR_018884) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/applied-bioinformatics-laboratories

Core provides computational analysis for high throughput genomic data, including but not limited to, next generation sequencing data. Our mission is to accelerate scientific discoveries by guiding experimental design, performing robust data quality assessment, and carrying out comprehensive computational analyses. Registration to iLab required.

Proper citation: New York University Grossman School of Medicine Applied Bioinformatics Laboratories Facility (RRID:SCR_019178) Copy   

•   Source: SciCrunch Registry