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https://www.research.uky.edu/pathology-core

Core facilitates COCVD projects by providing equipment and technical expertise to paraffin-embed and section tissue specimens and perform chemical staining of tissue sections to be examined, photographed and analyzed chromogenically by light microscopy.Training in immunohistochemical staining is available.

Proper citation: University of Kentucky College of Medicine, Lexington, Pathology Research Core Facility (RRID:SCR_018824) Copy   

•   Source: SciCrunch Registry

https://grcf.jhmi.edu/

Established to produce immortalized cell lines from human blood (EBV transformations). Offers genomics applications for single cells, including RNA-seq, gene expression profiling by qPCR and DNA amplification for whole-genome or targeted (exome or PCR-based analysis) through 10x Genomics Chromium platform (similar to Drop Seq). Offers custom genotyping to analyze short tandem repeats, variable number tandem repeats and single nucleotide polymorphisms.

Proper citation: Johns Hopkins University School of Medicine Genetic Resources Core Facility (RRID:SCR_018669) Copy   

•   Source: SciCrunch Registry

https://animalcare.umich.edu/business-services/ulam-pathology-core/

Our core is affiliated with the Unit for Laboratory Animal Medicine (ULAM) at the University of Michigan-Ann Arbor. We provide animal pathology services in support of non-GLP preclinical, translational, or basic science studies. Services include histology preparation, immunohistochemistry, animal hematology and serum chemistry assays, digital slide scanning/image analysis, and pathology interpretation by board-certified veterinary pathologists. Our core mission is to reduce bias and increase rigor within non-GLP animal research by providing high quality, documented, pathology support that may not be otherwise accessible within individual laboratories. Our laboratory maintains internal SOPs, documented quality control practices, and accountability/chain-of-custody records for all submissions. Additionally, we participate in an external quality control program through the Veterinary Laboratory Association.

Proper citation: University of Michigan ULAM Pathology Core Facility (RRID:SCR_018823) Copy   

•   Source: SciCrunch Registry

https://childrenshospital.corefacilities.org/service_center/show_external/3145

Core with advanced instrumentation in Light and Electron Microscopy.Core provides confocal, multiphoton microscopy,electron microscopy,image analysis.

Proper citation: Harvard Medical School PCMM Microscopy Core Facility (RRID:SCR_018822) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/center-biospecimen-research-development

Assists researchers and clinicians with molecular and morphologic characterization of normal and disease tissues of interest in support of biomarker discovery and translational research. Offers both routine and advanced histology immunohistochemistry, in situ and whole slide scanning services.

Proper citation: New York University School of Medicine Center for Biospecimen Research and Development Histology Core Facility (RRID:SCR_018304) Copy   

•   Source: SciCrunch Registry

https://vbrn.org/proteomics-services/

Provides central resource of mass spectrometry based proteomics technologies to identify, characterize and quantify target proteins in various biological and biomedical samples. Provides mass spectrometry expertise for analyzing proteins and peptides for proteomics studies, support for data analysis from proteomics measurements, training in proteomics methods, and experimental design.

Proper citation: Vermont University Proteomics Core Facility (RRID:SCR_018667) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/mbcl/

Core services including UMass Oligo Discount Program which provides discounted oligos to researchers, Reagent Program offers discounted pricing on TAQMAN, qPCR reagents, enzymes, etc. from ThermoFisher (Life Technologies/Ambion), and Empirical Biosciences, Fragment Analyzer Service, Sequencing Library Preparation, Sanger Sequencing and GeneMapper/ARISA. Provides DNA fragment analysis, Genotyping, and SPR services on an ABI capillary sequencer, and DNA/RNA fragment analysis on the Advanced Analytical (Agilent) Fragment Analyzer.

Proper citation: University of Massachusetts Medical School Molecular Biology Core Facility (RRID:SCR_018263) Copy   

•   Source: SciCrunch Registry

https://nyumc.ilab.agilent.com/service_center/show_external/4440?name=preclinical-imaging-laboratory

Core provides investigators with access to imaging technologies and strategies to image live animals on organ, tissue, cell, or molecular level.Core for studying and monitoring disease in small living subjects.Performs noninvasive and nonlethal three-dimensional imaging. Equipped with instruments for micromagnetic resonance imaging, micropositron emission tomography, X-ray microcomputed tomography, bioluminescence and fluorescence scanning, and high-frequency ultrasound.

Proper citation: New York University School of Medicine Langone Health Preclinical Imaging Laboratory (RRID:SCR_017937) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/metabolomics-laboratory

Core offers custom metabolomics services,specializes in mass spectrometry based metabolomics, offering global (untargeted) and targeted methods for metabolite identification and quantification.Commonly assayed targets include glycolytic and tricarboxylic acid (TCA) cycle intermediates, amino acids, nucleotides, and lipids. Using custom-targeted method, we can perform absolute or relative quantification, flux analysis, and biotransformation analysis.

Proper citation: New York University School of Medicine Langone Health Metabolomics Laboratory Core Facility (RRID:SCR_017935) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/microscopy-laboratory

Core offers comprehensive light and electron microscopy technologies. Our scientists use light microscopes and electron microscopes at resolutions ranging from centimeters to angstroms, providing clear and detailed images.We assist at every stage of your experiment, offering research-design consultation and instrument training, as well as guidance in study execution, analysis, and presentation for publication.

Proper citation: New York University School of Medicine Langone Health Microscopy Laboratory Core Facility (RRID:SCR_017934) Copy   

•   Source: SciCrunch Registry

http://nau.edu/enggen

Core facility for genomics research offers range of DNA sequencing, assistance and advising in planning, data acquisition, and data analysis. Provides genetic and genomic support to environmental and biomedical research projects. Creates education and training opportunities for students and professionals.

Proper citation: Northern Arizona University Environmental Genetics and Genomics Laboratory (RRID:SCR_017939) Copy   

•   Source: SciCrunch Registry

https://labs.gladstone.org/histology/index.html

Core provides technical assistance, training, consultation and assistance with all aspects of experimental design, sample preparation, image processing, and data analysis to scientists from Gladstone, UCSF, and Bay Area scientific community. Core is equipped with expertise in histological techniques including complex immunolabeling and histological image analysis, high-resolution imaging, confocal microscopy, light-sheet microscopy, spinning disk microscopy, and optical projection tomography and advanced image analysis.Histology Services includeTissue dissection and fixation, Paraffin processing and embedding,Frozen (cryo) processing and embedding,Tissue sectioning,Section staining.Microscopy Services include Epifluorescence, confocal and light sheet microscopy,Whole slide scanning,Microscopy consultation and training,Digital image analysis.

Proper citation: Gladstone Institutes Histology and Light Microscopy Core Facility (RRID:SCR_017940) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lmcf/

Provides access to instruments and training. Instruments including Dell Precision 7910 Analysis PC,Leica DMRXA Upright Widefield Microscope, Nikon E600 Upright Widefield Microscope, Nikon N-SIM structured illumination super-resolution and A1 laser scanning confocal microscope, Nikon Inverted Spinning Disk Confocal Microscope, Zeiss 510 Laser Scanning Confocal Microscope.

Proper citation: Colorado University at Boulder Light Microscopy Core Facility (RRID:SCR_018993) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/mcc

Core helps researchers investigate interactions between small molecules and biological systems by providing medicinal chemistry and chemical biology expertise and organic synthesis support.

Proper citation: Oregon Health and Science University Medicinal Chemistry Core Facility (RRID:SCR_019048) Copy   

•   Source: SciCrunch Registry

https://www.danforthcenter.org/our-work/core-facilities/phenotyping/

Core provides instruments including Scanalyzer 3D platform which consists of multiple digital imaging chambers connected to controlled environment Conviron growth house by conveyor belt system, resulting in continuous imaging loop and enables repeatedly image plants at multiple points throughout time.RGB imaging allows visualization and quantification of plant color and structural morphology. Near-infrared (NIR) enables visualization and quantification of plant water-use efficiency.Watering and weighing stations are customizable to deliver water and nutrients on specified schedule by volume or weight. Standard phenotyping services include operation and maintenance of LemnaTec Scanalyzer system, as well as technical support and troubleshooting.

Proper citation: Donald Danforth Plant Science Center Phenotyping Core Facility (RRID:SCR_019049) Copy   

•   Source: SciCrunch Registry

https://med.nyu.edu/research/scientific-cores-shared-resources/rodent-behavior-laboratory

Core offers equipment, facilities, and expertise to quantitatively assess broad range of behaviors in mice and rats, develop and validate novel paradigms to improve translation of preclinical behavioral results to clinically relevant outcome measures and create better tools for biobehavioral research.Core helped develop novel touch-screen tests to assess rodent attention, working memory, and reinforcement learning.

Proper citation: New York University School of Medicine Langone Health Rodent Behavior Laboratory (RRID:SCR_017942) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/core-facilities/intermountain-neuroimaging-consortium

Magnetic resonance imaging research facility. Provides Tesla Siemens MAGNETOM Prismafit MRI scanner, located at Center for Innovation and Creativity (CINC) on CU Boulder campus.

Proper citation: Colorado University at Boulder Intermountain Neuroimaging Consortium Core Facility (RRID:SCR_018990) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/massspec/

Offers analytical and instructional expertise in mass spectrometry with practical training and access to instrumentation.Located in room C1B90 of Jennie Smoly Caruthers Biotechnology Building houses six mass spectrometry systems.Instruments are interfaced with chromatographic system in order to separate complex mixture samples. Offers training for open access to some instruments including Thermo ISO LT GCMS, Synapt G2 HDMS, Agilent 6120 LCMS, and 4000 Q-trap QQQ instruments.

Proper citation: Colorado University at Boulder Central Analytical Mass Spectrometry Core Facility (RRID:SCR_018992) Copy   

•   Source: SciCrunch Registry

http://matci.facilities.northwestern.edu

Core offers characterization and sample preparation equipment. Characterization techniques include optical microscopy, thermal imaging, thermal analysis (DSC, TGA), hardness testing (Vicker, Knoop, Rockwell), electronic characterization (Hall Effect, Impedance Spectroscopy, Kelvin Probe, Charge Transport) and rheological characterization. Sample and surface preparation capabilities include mounting (castable mounts, hot pressure mounting, vacuum impregnation), cutting, sectioning and wafer dicing, polishing/grinding, electropolishing, ion beam milling and cross-sectional polishing. Tube and box furnaces are available with temperature range up to 1700C for thermal processing.

Proper citation: Northwestern University Materials Characterization and Imaging Core Facility (RRID:SCR_017947) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/bbc

Core provides statistical and big data analysis support. Performs data analysis and manuscript preparation services in Biostatistics, such as statistical genetics, longitudinal, survival, and high-throughput/high-dimensional omics data analysis; and Bioinformatics, such as DNA- and RNA-seq alignment, single cell DNA- and RNA-seq analysis, variant calling, differential expression and pathway analysis, data integration, online data submission, and custom script writing. Provides training to lab staff to enable them to perform future analyses.

Proper citation: Oregon Health and Science University Bioinformatics and Biostatistics Core Facility (RRID:SCR_017946) Copy   

•   Source: SciCrunch Registry