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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Q-Value Software
 
Resource Report
Resource Website
1+ mentions
Q-Value Software (RRID:SCR_008538) software resource Features: * This software takes a list of p-values resulting from the simultaneous testing of many hypotheses and estimates their q-values. A point-and-click interface is now available! * The q-value of a test measures the proportion of false positives incurred (called the false discovery rate) when that particular test is called significant. * A short tutorial on q-values and false discovery rates is provided with the manual. * Various plots are automatically generated, allowing one to make sensible significance cut-offs. * Several mathematical results have recently been shown on the conservative accuracy of the estimated q-values from this software. * The software can be applied to problems in genomics, brain imaging, astrophysics, and data mining. This research was supported in part by a National Science Foundation graduate research fellowship. has parent organization: Stanford University; Stanford; California nif-0000-31382 SCR_008538 Q-Value Software 2026-02-14 02:01:43 5
Apache Tomcat
 
Resource Report
Resource Website
1+ mentions
Apache Tomcat (RRID:SCR_008411) software resource Apache Tomcat is an open source software implementation of the Java Servlet and JavaServer Pages technologies. The Java Servlet and JavaServer Pages specifications are developed under the Java Community Process. Apache Tomcat is developed in an open and participatory environment and released under the Apache License version 2. Apache Tomcat is intended to be a collaboration of the best-of-breed developers from around the world. We invite you to participate in this open development project. Apache Tomcat powers numerous large-scale, mission-critical web applications across a diverse range of industries and organizations. Some of these users and their stories are listed on the PoweredBy wiki page. software, technology, application, java Yahoo ;
Microsoft ;
Google ;
Facebook ;
HP ;
Basis Technology ;
Covalent ;
IONA ;
AirPlus International ;
BlueNog ;
Intuit ;
Joost
nif-0000-30114 SCR_008411 Apache Tomcat 2026-02-14 02:01:42 7
GEDI
 
Resource Report
Resource Website
50+ mentions
GEDI (RRID:SCR_008530) GEDI software resource A program that opens a new perspective to the analysis of microarray data (e.g., gene expression profiling). Unlike traditional gene clustering software, GEDI is primarily sample-oriented rather than gene-oriented. By treating each high-dimensional sample, such as one microarray experiment, as an object, it accentuates the genome-wide response of a tissue or a patient and treats it as an integrated biological entity. Hence, GEDI honors the new spirit of a system-level approach in biology. Yet, it also allows the researcher to quickly zoom-in from global patterns onto individual genes that exhibit interesting expression behavior and retrieve gene-specific information. Therefore, GEDI unites a novel holistic perspective with the traditional gene-centered approach in molecular biology. GEDI allows experimental biologists or clinicians with no bioinformatics background to efficiently and intuitively navigate through a large number of expression profiles, each with a memorizable face, and inspect, group and collect them, like managing a stack of baseball cards. DYNAMIC ANALYSIS: The unique strength of GEDI, for which GEDI was originally developed, is that it can display the results of parallel monitoring of multiple high-dimensional time courses, such as the comparison of expression profile time evolution in response to a series of drugs. GEDI creates animated graphics showing how 10,000s of genes change their expression over time in response to 100s of separately tested drugs. STATIC ANAYLSIS: The signature graphical output of GEDI, the GEDI-mosaics provide a unique, one-glance visual engram that gives each microarray or other high-dimensional dataset a face. A characteristic of GEDI''s analysis is that it does not prejudicate any particular structure in the data (such as clusters or hierarchical organization). Thus, it allows the researcher to use human pattern recognition to perform a global first-level analysis of the data. Sponsor. The project was supported by the Air Force Office of Scientific Research and the National Health Institutes. It is distributed for free academic use by the Childrens Hospital, Boston., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30604 SCR_008530 The Gene Expression Dynamics Inspector, Gene Expression Dynamics Inspector 2026-02-14 02:01:35 73
Wide Tag
 
Resource Report
Resource Website
Wide Tag (RRID:SCR_008566) software resource Headquartered in Redwood City California, WideTag is a pioneer in architecting computing systems that integrate sensors, positioning devices and memory with social, Web 2.0-style services in applications that revolutionize business and push consumer technology.
nif-0000-31904 http://www.openspime.com SCR_008566 Wide Tag 2026-02-14 02:01:44 0
Program DynaFit
 
Resource Report
Resource Website
100+ mentions
Program DynaFit (RRID:SCR_008444) software resource Program DynaFit Analysis of (bio)chemical kinetics and equilibria Welcome to the DynaFit home page. Purpose Symbolic Notation Bibliographic Reference Numerical Methods Minimum System Requirements Purpose The main purpose of the program DynaFit is to perform nonlinear least-squares regression of chemical kinetic, enzyme kinetic, or ligand-receptor binding data. The experimental data can be either initial reaction velocities in dependence on the concentration of varied species (e.g., inhibitor concentration vs. velocity), or the reaction progress curves (e.g., time vs. absorbance). Symbolic Notation The main advantage in using the program DynaFit is in the ability to characterize the (bio)chemical reacting system in terms of symbolic, or stoichiometric, equations. For example, the ``slow, tight'''' inhibition of a dissociative dimeric enzyme is described by the following text: Monomer Monomer <==> Enzyme : k1 k2 Enzyme Inhibitor <==> Complex : k3 k4 Enzyme Substrate <==> ReactiveX : k5 k6 ReactiveX --> Product Enzyme : k7 k8 The names of chemical species (Monomer, Enzyme, etc.) are entirely arbitrary and can be freely chosen by the investigator. Bibliographic Reference If you publish any results obtained by using DYNAFIT, plase cite the following reference: Kuzmic, P. (1996) Anal. Biochem. 237, 260-273. Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase ABSTRACT A computer program with the code name DYNAFIT was developed for fitting either the initial velocities, or the time-course of enzyme reactions, to an arbitrary molecular mechanism represented symbolically by a set of chemical equations. Seven numerical tests and five graphical tests are applied to judge the goodness of fit. Experimental data on the inhibition of the dissociative dimeric proteinase from HIV were used in four test examples. A set of initial velocities was analyzed to see if a tight-binding inhibitor could bind to the HIV proteinase monomer. Three different sets of progress curves were analyzed (i) to determine the kinetic properties of an irreversible inhibitor; (ii) to investigate the dissociation and denaturation mechanism for the protease dimer; and (iii) to investigate the inhibition mechanism for a transient inhibitor. See a MEDLINE abstract with related references concerning the kinetics of HIV-1 protease. Numerical Methods The nonlinear regression module uses the Levenberg-Marquardt algorithm [1]. The time-course of (bio)chemical reactions is computed by the numerical integration of simultaous first-order ordinary differential equations, using the Livermore Solver of ODe Systems (LSODE, [2]). The composition of complex mixtures at equilibrium (e.g., in the concentration jump experiment where a complex mixture is incubated prior to the addition of a reagent) is computed by solving simultaneous nonlinear algebraic equations, namely, the mass balance equations for the component species, by using the multidimensional Newton-Raphson method [3]. References G. A. F. Seber and C. J. Wild (1989) Nonlinear Regression, Wiley, New York, p. 624. A. C. Hindmarsh (1983) ODEPACK: a systematized collection of ODE solvers; in Scientific Computing, ed. R. S. Stepleman et al., North Holland, Amsterdam, pp. 55--64. E. Kreyszig (1993) Advanced Engineering Mathematics; 7th ed., John Wiley, New York, p. 929. Minimum System Requirements DynaFit for Windows Intel Pentium III or Celeron class 800 MHz or faster processor Microsoft Windows XP (SP1) or 2000 (SP2) 128 MB RAM 20 MB Hard Disk Space Ethernet Network Interface Card required for license activation(1) CD/DVD-ROM drive required for software installation(2) (1) The Network Interface Card is used to compute a unique Computer ID, tied to a particular DynaFit license. Essentially the Computer ID required for license activation is an encrypted Media Access Control (MAC address) associated with the given Network Card. (2) CD/DVD-ROM is not required if the software is being installed by using the downloadable installer file dynafit-install.zip. Sponsor. This work has been supported by the NIH, grant No. R43 AI52587-02 and the U.S. Department of Defense, U.S. Army Medical Research and Materials Command, Ft. Detrick, MD, administered by the Pacific Telehealth & Technology Hui, Honolulu, HI, contract No. V549P-6073. nif-0000-30477 SCR_008444 DynaFit 2026-02-14 02:01:39 127
Public Health Resources Unit
 
Resource Report
Resource Website
1+ mentions
Public Health Resources Unit (RRID:SCR_008564) software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Tools were developed by the Critical Appraisal Skills Programme (CASP) to help with the process of critically appraising articles of the following types of research. These are available and free to download for personal use. THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-31450 http://www.sph.nhs.uk/what-we-do/public-health-workforce/resources/critical-appraisals-skills-programme http://www.phru.nhs.uk/Pages/PHD/resources.htm SCR_008564 PHRU 2026-02-14 02:01:43 1
LAGAN
 
Resource Report
Resource Website
50+ mentions
LAGAN (RRID:SCR_008558) software resource About the LAGAN Toolkit The LAGAN Tookit consists of four components: CHAOS CHAOS is a pairwise local aligner optimized for non-coding, and other poorly conserved regions of the genome. It uses both exact matching and degenerate seeds, and is able to find homology in the presence of gaps. LAGAN LAGAN is our highly parametrizable pairwise global alignment program. It takes local alignments generated by CHAOS as anchors, and limits the search area of the Needleman-Wunsch algorithm around these anchors; Multi-LAGAN Multi-LAGAN is a generalization of the pairwise algorithm to multiple sequence alignment. M-LAGAN performs progressive pairwise alignments, guided by a user-specified phylogenetic tree. Alignments are aligned to other alignments using the sum-of-pairs metric. Shuffle-LAGAN Shuffle-LAGAN is a novel glocal alignment algorithm that is able to find rearrangements (inversions, transpositions and some duplications) in a global alignment framework. It uses CHAOS local alignments to build a map of the rearrangements between the sequences, and LAGAN to align the regions of conserved synteny. The website uses scripts written by Alex Poliakov. The website was designed by Marina Sirota. has parent organization: Stanford University; Stanford; California DOI:10.1101/gr.926603 OMICS_08469, nif-0000-31432 https://sources.debian.org/src/lagan/ SCR_008558 LAGAN 2026-02-14 02:01:42 82
SAFC
 
Resource Report
Resource Website
100+ mentions
SAFC (RRID:SCR_008554) commercial organization THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. A business division of Sigma-Aldrich Corporation, focusing on providing custom manufactured products and specialized services used in the industrial development and manufacturing, including processes, that bring new drugs and new electronic products to market., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-31481 SCR_008554 SAFC 2026-02-14 02:01:36 380
Classifier Visualization in R
 
Resource Report
Resource Website
10+ mentions
Classifier Visualization in R (RRID:SCR_008551) software resource ROCR is a package for evaluating and visualizing the performance of scoring classifiers in the statistical language R. It features over 25 performance measures that can be freely combined to create two-dimensional performance curves. Standard methods for investigating trade-offs between specific performance measures are available within a uniform framework, including receiver operating characteristic (ROC) graphs, precision/recall plots, lift charts and cost curves. ROCR integrates tightly with R''s powerful graphics capabilities, thus allowing for highly adjustable plots. Being equipped with only three commands and reasonable default values for optional parameters, ROCR combines flexibility with ease of usage. Performance measures that ROCR knows: Accuracy, error rate, true positive rate, false positive rate, true negative rate, false negative rate, sensitivity, specificity, recall, positive predictive value, negative predictive value, precision, fallout, miss, phi correlation coefficient, Matthews correlation coefficient, mutual information, chi square statistic, odds ratio, lift value, precision/recall F measure, ROC convex hull, area under the ROC curve, precision/recall break-even point, calibration error, mean cross-entropy, root mean squared error, SAR measure, expected cost, explicit cost. ROCR features: ROC curves, precision/recall plots, lift charts, cost curves, custom curves by freely selecting one performance measure for the x axis and one for the y axis, handling of data from cross-validation or bootstrapping, curve averaging (vertically, horizontally, or by threshold), standard error bars, box plots, curves that are color-coded by cutoff, printing threshold values on the curve, tight integration with Rs plotting facilities (making it easy to adjust plots or to combine multiple plots), fully customizable, easy to use (only 3 commands). ROCR can be used under the terms of the GNU General Public License. Running within R, it is platform-independent. has parent organization: Max-Planck-Institute for Informatics; Saarbrucken; Germany PMID:16096348 nif-0000-31415 SCR_008551 ROCR: Classifier Visualization in R, ROCR 2026-02-14 02:01:42 15
Bork Group's WU-BLAST2 Search Service at EMBL
 
Resource Report
Resource Website
1+ mentions
Bork Group's WU-BLAST2 Search Service at EMBL (RRID:SCR_008431) data or information resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. This portal let you search BLAST through the WU-BLAST2 Search Service provided by the Bork Group at EMBL. Sponsors: This resource is supported by EMBL., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. has parent organization: European Molecular Biology Laboratory THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30210 http://archive.is/dove.embl-heidelberg.de SCR_008431 BLAST2 2026-02-14 02:01:34 7
Cython C-Extensions for Python
 
Resource Report
Resource Website
100+ mentions
Cython C-Extensions for Python (RRID:SCR_008466) software resource Cython is a language that makes writing C extensions for the Python language as easy as Python itself. Cython is based on the well-known Pyrex, but supports more cutting edge functionality and optimizations. The Cython language is very close to the Python language, but Cython additionally supports calling C functions and declaring C types on variables and class attributes. This allows the compiler to generate very efficient C code from Cython code. This makes Cython the ideal language for wrapping external C libraries, and for fast C modules that speed up the execution of Python code. Sponsor. Google and Enthought funded Dag Seljebotn to greatly improve Cython integration with NumPy. Kurt Smith and Danilo Freitas were funded through the Google Summer of Code program to work on improved Fortran and C support respectively. is related to: Python Programming Language
is required by: TomoMiner
nif-0000-30401 SCR_008466 Cython 2026-02-14 02:01:42 135
Ultrasome
 
Resource Report
Resource Website
Ultrasome (RRID:SCR_008465) Ultrasome software resource An efficient methodology for detecting and delineating gains and losses of chromosomal material in DNA copy-number data. is listed by: OMICtools
has parent organization: Broad Institute
PMID:19228802 Acknowledgement requested, Free for academic use OMICS_00737 SCR_008465 2026-02-14 02:01:39 0
D. rerio Blast Server
 
Resource Report
Resource Website
1+ mentions
D. rerio Blast Server (RRID:SCR_008461) service resource This Blast server offers searches against all D. rerio finished and unfinished clones in the Sanger sequencing pipeline. You can now also search the de novo assemblies generated from sequencing of one doubled haploid homozygous individual of each the AB and Tuebingen strain. Both fish were sequenced to ~40x coverage using Illumina GA sequencing technology and the sequences were assembled using Phusion2, resulting in a 1,33 Gb AB and a 1.48 Gb Tuebingen assembly. Due to the short reads and short inserts and no integration of physical or genetic map data, both assemblies are highly fragmented - with an N50 contig size of about 5kb. Mis-assembly errors may also be present in the contigs. Please note these assemblies are independent additions to the assemblies released by the zebrafish genome project and are intended to aid identification of polymorphisms between these two strains. Charity. Genome Research Limited is a charity registered in England with number 1021457 has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom nif-0000-30406 SCR_008461 D. rerio 2026-02-14 02:01:42 6
Yahoo Developer Network
 
Resource Report
Resource Website
50+ mentions
Yahoo Developer Network (RRID:SCR_008594) software resource The YUI Library is a set of utilities and controls, written with JavaScript and CSS, for building richly interactive web applications using techniques such as DOM scripting, DHTML and AJAX. YUI is available under a BSD license and is free for all uses. YUI is proven, scalable, fast, and robust. Built by frontend engineers at Yahoo! and contributors from around the world, it''s an industrial-strength JavaScript library for professionals who love JavaScript. nif-0000-31921 SCR_008594 Yahoo 2026-02-14 02:01:43 54
WinLTP
 
Resource Report
Resource Website
100+ mentions
WinLTP (RRID:SCR_008590) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on Jan 16th 2025. WinLTP is a stimulation, data acquisition and on-line analysis electrophysiological software for studying Long-Term Potentiation (LTP), Long-term Depression (LTD), and related phenomena. WinLTP is multitasking and simultaneously runs 1) LTP stimulus/acquisition/analyzing sweeps with protocol scripting, and 2) continuous acquisition saving Axon Binary Files (abf). WinLTP runs on Windows PCI bus computers and uses National Instruments PCI M-Series boards and Axon Instruments'' Digidata 1320A and 1322A data acquisition boards. Other software that can use the M-Series boards includes Axograph Scientific''s AxoGraph X, WaveMetrics'' IGOR, National Instruments'' LabView, John Dempster''s Strathclyde Electrophysiology Suite (WinWCP and WinEDR), Silver lab''s Nclamp, and QUB data acquisition., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. has parent organization: University of Bristol; Bristol; United Kingdom DOI:10.1016/j.jneumeth.2006.12.018 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-31907 SCR_008590 WinLTP 2026-02-14 02:01:41 218
Motif Extractor
 
Resource Report
Resource Website
100+ mentions
Motif Extractor (RRID:SCR_008628) software resource motif-x (short for motif extractor) is a software tool designed to extract overrepresented patterns from any sequence data set. The algorithm is an iterative strategy which builds successive motifs through comparison to a dynamic statistical background. has parent organization: Harvard University; Cambridge; United States nif-0000-32002 SCR_008628 Motif-X 2026-02-14 02:01:37 148
DE-ID Data Corp
 
Resource Report
Resource Website
1+ mentions
DE-ID Data Corp (RRID:SCR_008668) software resource A commercial organization that suppplies software which creates separate HIPAA-compliant repositories of de-identified patient records and reports. This software allows clinicians, researchers, and administrative leadership to safely access, search, share, and analyze de-identified patient-level data. DE-ID can be acquired as stand-alone tool or integrated with data networks or clinical information systems. clinical, data, patient protection, surgical report nif-0000-33387 SCR_008668 DE-ID Data Corp 2026-02-14 02:01:38 1
SUN Interface Engine
 
Resource Report
Resource Website
SUN Interface Engine (RRID:SCR_008659) SUN Interface Engine software resource Oracle''s complete, open, and integrated product strategy provides flexibility and choice to our customers across their IT infrastructure. Now, with Sun server, storage, operating-system, and virtualization technology, Oracle is the only vendor able to offer a complete technology stack in which every layer is integrated to work together as a single system. Oracle''s open architecture and multiple operating-system options gives our customers unmatched benefits, including excellent system availability, scalability, energy efficiency, powerful performance, and low total cost of ownership Starting more than 30 years ago with Oracle''s innovative relational database, the Oracle stack today includes Oracle Enterprise Linux, Oracle VM, Oracle Fusion Middleware, and the largest and most complete set of industry and business applications software on the market. The addition of Sun storage and systems technology makes the Oracle stack complete. Oracle integrates every layer of the IT stack to deliver compelling value, based on high system availability and security, stunning performance, and low TCO. Only Oracle can offer this stack advantage to its customers through deep and seamless integration between the tiers that our competitors cannot match. is listed by: Biositemaps nif-0000-33145 SCR_008659 2026-02-14 02:01:42 0
Disease Phenotype Ontology
 
Resource Report
Resource Website
10+ mentions
Disease Phenotype Ontology (RRID:SCR_008687) data or information resource, ontology, controlled vocabulary The Disease Ontology group has developed a set of standard representations of phenotypes associated with diseases useful in bioinformatics applications. These are formalized into an ontological structure and are encoded in OWL. Neurodegenerative diseases have a wide and complex range of biological and clinical symptoms. While neurodegenerative diseases share many pathological features in common, they also contain unique signatures. Animal models of these disorders are key to translational research. However, animal models typically replicate only a subset of disease features or display features that are only indirectly related to a given disorder, whose relationship to the human condition may be across several diseases. Matching animal models to human diseases is therefore a significant informatics challenge. We have been working to develop ontologies that capture essential features of neurodegenerative diseases and associated animal models in a way that allows more flexible matching of animal models to human disorders and in a way that makes explicit commonalities and differences among animal models and human neurodegenerative disease. Creating ontologies for diseases and disorders is a very challenging task (Gupta et al., 2003) because of the complexity of the disorders and because of the limitations of current ontology formalisms. In order to simplify the approach and make it practical for use in information systems, we have focused on formal descriptions of phenotypes associated with diseases and animal models rather than on a formal model of the disease process itself. We employ the modular ontologies developed as part of the Neuroscience Information Framework (NIF: http://nif.nih.gov) and the Phenotype and Trait Ontology (PATO), an ontology of qualities associated with biological phenotypes, to create a flexible template for creating phenotypic statements at the class and instance levels. We show how these phenotypes can be used to look for commonalities across multiple neurodegenerative conditions and animal models. has parent organization: University of California at San Diego; California; USA nif-0000-35922 SCR_008687 DPO 2026-02-14 02:01:38 40
OligoPicker
 
Resource Report
Resource Website
1+ mentions
OligoPicker (RRID:SCR_008720) OligoPicker software resource Software to help selecting up to five oligo probes for each of the DNA sequences you provided for microarray spotting. is listed by: OMICtools PMID:12724288 GNU General Public License, Acknowledgement requested OMICS_00830 SCR_008720 2026-02-14 02:01:38 3

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