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https://www.med.upenn.edu/neuronsrus/

Core supplies suspensions of neuronal cells prepared from rodent brain for various downstream applications, including primary cell culture. Supplies rat or mouse cells isolated from cortex or hippocampus either in suspension or plates. Custom dissection services are available for other brain regions or for user supplied genetically modified mice.

Proper citation: University of Pennsylvania Perelman School of Medicine Neurons R Us Core Facility (RRID:SCR_022421) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/OCRCBioTrust/

Provides specimens including gynecologic cancer specimens such as fresh and frozen tissues, plasma, serum, peripheral blood mononuclear cells, blood, formalin fixed paraffin embedded (FFPE) samples, and Tissue Microarrays (TMAs). All samples collected have clinical annotation including demographic patient profiles, pathological and clinical notations, treatment history, and detail disease information, etc. We are building and maintaining centralized research database according to HIPPA specifications and Penn IRB standards.

Proper citation: University of Pennsylvania Perelman School of Medicine Ovarian Cancer Research Center Tumor BioTrust Collection Core Facility (RRID:SCR_022387) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/NBTC.html

Core provides equipment and services to investigate behavior phenotypes of models related to neurological and other disorders. Core is utilized by scientists across disciplines that are interested in behavioral consequences of unique physiological disruptions (e.g., metabolic, drugs etc.). Provides assessment of many domains of behavior including sensory, motor, social, communication, affect related behaviors and learning and memory. NTC was established in 2012 through generous startup funds from the Penn School of Medicine, the Institute for Translational Medicine and Therapeutics (ITMAT), Center for Sleep and Circadian Neurobiology (CSCN) and Penn Medicine Neuroscience Center (PMNC).

Proper citation: University of Pennsylvania Perelman School of Medicine Neurobehavior Testing Core Facility (RRID:SCR_022386) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/saif-small-animal-imaging-facility

Core provides comprehensive suite of imaging modalities including magnetic resonance imaging (MRI), spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US). In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of SAIF are devoted to radiochemistry and image analysis.

Proper citation: University of Pennsylvania Perelman School of Medicine Small Animal Imaging Core Facility (RRID:SCR_022385) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/genomic-analysis-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 8th,2024. Facility offers sequencing services on three platforms, gold standard Sanger sequencing on ABI capillary sequencers, next generation sequencing (NGS) on Ion Torrent PGM and S5 and, Illumina MiSeq along with experimental design and data analysis.NGS service includes library preparation for multiple applications including targeted sequencing, RNA-Seq and Exome-Seq. Capillary sequencers also enable microsatellite genotyping and fragment analysis for VNTR, SNaPshot and Human Cell Line Authentication. Molecular biological services include PCR, cloning, subcloning, mutagenesis, construct preparation and, plasmid DNA preps at different scales.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis DNA Sequencing Core Facility (RRID:SCR_022383) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/fmch/mixed-methods-research-lab

Fosters the use of qualitative and mixed methods research methodologies with focus on integrating key stakeholder perspectives and goals into research designs. Collaborates with investigators to address timely, pressing questions across diverse disciplines and works with investigators to provide conceptual as well as technical support for broad research programs, including clinical, community based, and implementation science research questions.

Proper citation: University of Pennsylvania Perelman School of Medicine Mixed Methods Research Lab Core Facility (RRID:SCR_022418) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-microbial-culture-and-metabolomics-core

Provides equipment for aerobic and anaerobic culture of microbial species in both batch and continuous systems, as well as targeted metabolomic services of amino, bile, and short chain fatty acids. Offers training and usage for culture equipment; consultation regarding experimental design, and; anaerobic culture services. Examples of culture studies include isolation of microbial taxa from mammalian samples; interrogation of the physiology of microbial strains under different conditions (e.g., anaerobic/microaerobic/aerobic, differing nutrient limitations) using isolated strains or strains obtained from culture collections (another service offered by the core); co-culturing of defined microbial consortia to investigate microbe-microbe interactions, and; preparation of microbial products (live bacteria, heat-killed bacteria, bacterial supernatants) from single or defined-mixed microbial cultures for use in mammalian cell culture and/or animal model systems.

Proper citation: University of Pennsylvania Perelman School of Medicine Microbial Culture and Metabolomics Core Facility (RRID:SCR_022417) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/host-microbial-analytic-and-repository-core-h-marc.html

Core within Division of Gastroenterology provides services which�represents intersection between host and their microbes in both�preclinical and clinical human subject research.Offers human biospecimen repository with associated clinical metadata, instrumentation/access to critical analytic services to characterize expression (i.e. genomics, transcriptomics, metabolomics, microbial culture, etc.) in both microbes and�their mammalian hosts, as well as expertise to extend pre-clinical in vitro and animal model research into human clinical domain. �

Proper citation: University of Pennsylvania Perelman School of Medicine Host-Microbial Analytic and Repository Core Facility (RRID:SCR_022416) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/jf/bsbcore/index.html

Provides unique equipment and expertise to facilitate modern biophysical characterization and structural analysis of proteins and other biomolecules., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Johnson Foundation Biophysical and Structural Biology Core Facility (RRID:SCR_022414) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/sdab/

Core works with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators.Services include protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates support available with HUP and CHOP Center for Human Phenomic Science (CHPSs), expertise and resources of faculty in Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), Biostatistics Analysis Center (BAC), and Biostatistics and Data Management Core (BDMC) at CHOP.

Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Study Design and Biostatistics Core Facility (RRID:SCR_022413) Copy   

•   Source: SciCrunch Registry

https://med-upenn.corefacilities.org/sc/4405/crispr-cas9-mouse-targeting-core/?tab=about

Core facilitates use of CRISPR/Cas9 genome editing technology to generate novel mouse genetic tools.

Proper citation: University of Pennsylvania Perelman School of Medicine CRISPR Cas9 Mouse Targeting Core Facility (RRID:SCR_022378) Copy   

•   Source: SciCrunch Registry

https://www.sbpdiscovery.org/biomedical-research/shared-resources/proteomics

Facility provides mass spectrometry based proteomics services with methods tailored to needs of scientific investigators for routine mass spectrometric analysis of peptides and proteins, identification of novel proteins, characterization of post translational modifications, and quantitative proteomics analysis of simple to complex biological samples. Core identifies, validates and develops new methods designed for characterization and identification of biologically important proteins. Supports users with software applications and development, data analysis and experimental design of proteomics studies. Expands its capabilities in large scale differential proteomics analysis and phosphoproteomics for unbiased discovery of potential biomarkers and mapping protein profiles.

Proper citation: Sanford Burnham Prebys Medical Discovery Institute Proteomics Core Facility (RRID:SCR_022225) Copy   

•   Source: SciCrunch Registry

https://www.sc.edu/study/colleges_schools/pharmacy/research_and_practice/research_centers_and_facilities/microarray_core_facility/index.php

Services include RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, assisting customers in design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. Provides support for quantitation and quality assessment of DNA, RNA and protein on Agilent 2100 Bioanalyzer. Provides training and support for Agilent and Affymetrix Hybridization oven users. Provides support for microarray scanning and for data analysis with variety of software packages for both Agilent and Affymetrix platforms.Quantity and quality of your RNA, DNA, proteins and cells are determined with help of Agilent 2100 Bioanalyzer.

Proper citation: University of South Carolina at Columbia College of Pharmacy Microarray Core Facility (RRID:SCR_022211) Copy   

•   Source: SciCrunch Registry

http://uoft.me/AIMS

Core mass spectrometry facility located in Department of Chemistry, University of Toronto, which houses several mass spectrometers. Services include:High resolution, accurate mass determinations of small molecules via EI, ESI and DART ionization;Mass determinations of intact peptides and proteins via ESI-QTOF-MS and MALDI-MS; HPLC-MS/MS analysis of protein digests via ESI-QTOF-MS; Quantitative analysis via HPLC-MS/MS using QqQ instrumentation.

Proper citation: University of Toronto Advanced Instrumentation for Molecular Structure Mass Spectrometry Laboratory Core Facility (RRID:SCR_022210) Copy   

•   Source: SciCrunch Registry

https://micron.hms.harvard.edu/

Light microscopy core is open to HMS researchers, including Affiliated hospitals. Supports imaging modalities ranging from wide field, TIRF, spinning disk and single point scanning confocal, multiphoton, FLIM and supper resolution. Microscopes are embedded within Departments of Microbiology, Immunology, and Genetics, housed in five microscope rooms on five floors of NRB and HIM.

Proper citation: Harvard Medical School Microscopy Resources On the North Quad Core Facility (RRID:SCR_022209) Copy   

•   Source: SciCrunch Registry

https://www.biomedicas.unam.mx/servicios/unidad-de-microscopia/

Core is specialized in stereology techniques, live cell imaging, CLSM (confocal microscopy), and STORM. Provided instruments include CONFOCAL microscopes Zeiss LSM 5 Pascal, Olympus BX51-WI,Olympus IX71 inverted microscope, Nikon Labophot-2 microscope,Nikon Optiphot 2 microscope.

Proper citation: National Autonomous University of Mexico Microscopy Core Facility (RRID:SCR_022204) Copy   

•   Source: SciCrunch Registry

http://www.cemib.unicamp.br

Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.

Proper citation: State University of Campinas Multidisciplinary Center for Biological Investigantion on Laboratory Animals Science Core Facility (RRID:SCR_022203) Copy   

•   Source: SciCrunch Registry

https://vtpb.tamu.edu/flow-cytometry/

Provides flow cytometry experimental design, data collection, data analysis and cell sorting services; training for flow cytometers, imaging flow cytometer, and data analysis using IDEAS and FlowJo software;staff assisted flow cytometry and imaging flow cytometry data acquisition, cell sorting, and data analysis, experimental design and consultation services. FCF currently has Beckman Coulter Moflo Astrios cell sorter, Luminex/Amnis Image Stream X Mark II, Luminex/Amnis Cell Stream, and Becton Dickinson Accuri C6 flow cytometer. Astrios cell sorter is housed in ClassII BSC and has 3 lasers (405nm, 488nm, 642nm) and 11 detectors and can sort up to 6 populations simultaneously. Image Stream X Mark II is equipped with 20x, 40x, 60x objectives, 4 lasers (405nm, 488nm, 561nm, 642nm), 10 detection channels, EV mode for small particle detection, and an autosampler.Cell Stream is equipped with 3 lasers (405nm, 488nm, 642nm), 13 detection channels, EV mode for small particle detection, and autosampler. Accuri C6 is equipped with 2 lasers (488nm, 642nm), and 4 detection channels.

Proper citation: Texas A and M University College of Veterinary Medicine and Biomedical Sciences Flow Cytometry Core Facility (RRID:SCR_022169) Copy   

•   Source: SciCrunch Registry

https://mcf.tamu.edu/

Core provides access to instrumentation essential for studies of surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. Core provides training to students and faculty on instrumentation as well as consolation of measurements needs and data interpretation, supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.Supports collaborative research projects with outside industrial users.

Proper citation: Texas A and M University Materials Characterization Core Facility (RRID:SCR_022202) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/genomics-innovation-hub

Core complements services provided by BRC Genomics Facility.Working on collaborative model, protocol and method development by early adopters pave the way for larger scale production services.

Proper citation: Cornell University BRC Genomics Innovation Hub Core Facility (RRID:SCR_022547) Copy   

•   Source: SciCrunch Registry