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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PredictNLS
 
Resource Report
Resource Website
10+ mentions
PredictNLS (RRID:SCR_003133) PredictNLS production service resource, analysis service resource, service resource, software resource, data analysis service Software automated tool for analysis and determination of Nuclear Localization Signals (NLS). Predicts that your protein is nuclear or finds out whether your potential NLS is found in our database. The program also compiles statistics on the number of nuclear/non-nuclear proteins in which your potential NLS is found. Finally, proteins with similar NLS motifs are reported, and the experimental paper describing the particular NLS are given. bio.tools, nuclear localization signal, protein, protein sequence is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: ROSTLAB
has parent organization: Columbia University; New York; USA
DOI:10.1093/embo-reports/kvd092 Free, Available for download, Freely available nif-0000-31416, OMICS_01633, SCR_008553, biotools:predictnls https://www.rdocumentation.org/packages/propagate/versions/1.0-4/topics/predictNLS SCR_003133 Prediction and Analysis of Nuclear Localization Signals 2026-02-17 10:00:12 30
LUMPY
 
Resource Report
Resource Website
100+ mentions
LUMPY (RRID:SCR_003253) software application, standalone software, data processing software, data analysis software, software resource, simulation software Software package as probabilistic framework for structural variant discovery. Capable of integrating any number of SV detection signals including those generated from read alignments or prior evidence. Simplified wrapper for standard analyses, LUMPY Express, can also be executed. probabilistic, framework, structural, variant, discovery is listed by: OMICtools
is listed by: Debian
has parent organization: University of Virginia; Virginia; USA
NHGRI R01 HG006693;
NIH Office of the Director DP2 OD006493;
Burroughs Wellcome Fund Career Award
PMID:24970577 Free, Available for download, Freely available OMICS_04674 https://sources.debian.org/src/lumpy-sv/ SCR_003253 lumpy-sv, LUMPY Express 2026-02-17 09:59:58 447
SplicingCompass
 
Resource Report
Resource Website
1+ mentions
SplicingCompass (RRID:SCR_003249) software application, data processing software, data analysis software, software resource, sequence analysis software Software for detection of differential splicing between two different conditions using RNA-Seq data. differential splicing, splicing event, exon removal, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23449093 Free, Available for download, Freely available biotools:splicingcompass, OMICS_01340 https://github.com/KoenigLabNM/SplicingCompass SCR_003249 Splicing Compass 2026-02-17 10:00:07 2
PathGuide: the pathway resource list
 
Resource Report
Resource Website
10+ mentions
PathGuide: the pathway resource list (RRID:SCR_003248) Pathguide data or information resource, catalog, database Catalog containing information about 547 biological pathway related resources and molecular interaction related resources. Databases that are free and those supporting BioPAX, CellML, PSI-MI or SBML standards are respectively indicated. gene interaction network, metabolic pathway, signaling pathway, pathway diagram, protein-compound interaction, protein-protein interaction, protein sequence focused, transcription factor, gene regulatory network, transcription factor target, genetic interaction, pathway, molecular interaction, FASEB list is listed by: OMICtools
is related to: PSI-MI
is related to: bioDBcore
is related to: Biological Pathways Exchange
is related to: CellML
is related to: SBML
is related to: Biological Pathways Exchange
PMID:16381921 Free, Freely available SciRes_000148, OMICS_01701, nif-0000-00640 SCR_003248 2026-02-17 09:59:57 47
deFuse
 
Resource Report
Resource Website
50+ mentions
deFuse (RRID:SCR_003279) software application, data processing software, data analysis software, sequence analysis software, software resource, software toolkit Software package for gene fusion discovery using RNA-Seq data. It uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. rna sequencing, gene fusion, paired end alignment, split read, fusion boundary, bio.tools uses: SAMTOOLS
uses: Bowtie
uses: BLAT
uses: GMAP
uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
British Columbia Cancer Foundation ;
Vancouver General Hospital Foundation ;
Genome Canada ;
Michael Smith Foundation for Health Research ;
Canadian Breast Cancer Foundation ;
Canadian Institutes of Health Research's Bioinformatics Training Program
PMID:21625565 Free, Available for download, Freely available biotools:defuse, OMICS_01345 https://sourceforge.net/projects/defuse/
http://compbio.bccrc.ca/software/defuse/
https://bio.tools/defuse
http://sourceforge.net/apps/mediawiki/defuse/index.php?title=Main_Page SCR_003279 2026-02-17 10:00:15 95
MultiLoc
 
Resource Report
Resource Website
10+ mentions
MultiLoc (RRID:SCR_003151) MultiLoc production service resource, analysis service resource, service resource, software resource, data analysis service An extensive high-performance subcellular protein localization prediction system that incorporates phylogenetic profiles and Gene Ontology terms to yield higher accuracies compared to its previous version. Moreover, it outperforms other prediction systems in two benchmarks studies. A downloadable version of MultiLoc2 for local use is also available. subcellular localization, protein, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tubingen; Tubingen; Germany
PMID:19723330 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01628, biotools:multiloc2 https://bio.tools/multiloc2 SCR_003151 2026-02-17 10:00:05 40
GeneScissors
 
Resource Report
Resource Website
1+ mentions
GeneScissors (RRID:SCR_003146) software application, data processing software, data analysis software, software resource, sequence analysis software Software for detecting and correcting spurious transcriptome inference due to RNAseq reads misalignment. transcriptome inference, read misalignment, rna seq is listed by: OMICtools
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
works with: Cufflinks
works with: TopHat
PMID:23812996 Free, Available for download, Freely available OMICS_01232 SCR_003146 Gene Scissors 2026-02-17 09:59:56 2
Primer3
 
Resource Report
Resource Website
10000+ mentions
Primer3 (RRID:SCR_003139) Primer3 production service resource, analysis service resource, service resource, software resource, data analysis service Tool used to design PCR primers from DNA sequence - often in high-throughput genomics applications. It does everything from mispriming libraries to sequence quality data to the generation of internal oligos. primer, primer design, polymerase chain reaction, pcr primer, dna sequence, c, perl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Primer3Plus
is related to: Primer-BLAST
has parent organization: University of Tartu; Tartu; Estonia
NHGRI R01-HG00257;
NHGRI P50-HG00098
PMID:22730293
PMID:17379693
DOI:10.1385/1-59259-192-2:365
DOI:10.1385/1-59259-192-2:365
Free, Freely available nlx_156833, OMICS_02325, biotools:primer3 http://bioinfo.ut.ee/primer3-0.4.0/
http://sourceforge.net/projects/primer3/
http://frodo.wi.mit.edu/primer3
https://bio.tools/primer3
https://sources.debian.org/src/primer3/
https://sources.debian.org/src/primer3/
SCR_003139 Primer3web - Pick primers from a DNA sequence, Primer3 - PCR primer design tool, Primer3web 2026-02-17 10:00:10 10957
Genedata Expressionist
 
Resource Report
Resource Website
10+ mentions
Genedata Expressionist (RRID:SCR_003298) data management software, software application, data processing software, data analysis software, software resource Software that provides data processing, analysis, management, and reporting of metabolomics, proteomics and biotherapeutics characterization studies based on mass spectrometry. It can process raw data from various MS instruments, serve MS processing, analysis and reporting needs, and ensure reproducibility and traceability of results. mass spectrometry data processing, mass spectrometry data analysis, mass spectrometry data management, omics software is listed by: OMICtools THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00761 SCR_003298 Genedata Expressionist for Genomic Profiling 2026-02-17 10:00:08 10
Talking Glossary of Genetic Terms
 
Resource Report
Resource Website
Talking Glossary of Genetic Terms (RRID:SCR_003215) Talking Glossary data or information resource, narrative resource, database, training material Glossary of Genetic Terms to help everyone understand the terms and concepts used in genetic research. In addition to definitions, specialists in the field of genetics share their descriptions of terms, and many terms include images, animation and links to related terms. glossary, image, genetic, gene, education is listed by: OMICtools
has parent organization: National Human Genome Research Institute
NHGRI The community can contribute to this resource nlx_156942, OMICS_01555 SCR_003215 NHGRI Talking Glossary, NHGRI Talking Glossary of Genetic Terms 2026-02-17 10:00:06 0
Database of Interacting Proteins (DIP)
 
Resource Report
Resource Website
100+ mentions
Database of Interacting Proteins (DIP) (RRID:SCR_003167) DIP storage service resource, data or information resource, production service resource, analysis service resource, database, service resource, data analysis service, data repository Database to catalog experimentally determined interactions between proteins combining information from a variety of sources to create a single, consistent set of protein-protein interactions that can be downloaded in a variety of formats. The data were curated, both, manually and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks. Tools are available to analyze, visualize and integrate user's own experimental data with the information about protein-protein interactions available in the DIP database. The DIP database lists protein pairs that are known to interact with each other. By interact they mean that two amino acid chains were experimentally identified to bind to each other. The database lists such pairs to aid those studying a particular protein-protein interaction but also those investigating entire regulatory and signaling pathways as well as those studying the organization and complexity of the protein interaction network at the cellular level. Registration is required to gain access to most of the DIP features. Registration is free to the members of the academic community. Trial accounts for the commercial users are also available. blast, cellular network, ligand-receptor complex, ligand, network, protein, protein interaction, protein ligand, protein-protein interaction, protein receptor, receptor, sequence, interaction, regulatory pathway, signaling pathway, protein binding, bio.tools, FASEB list is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: IMEx - The International Molecular Exchange Consortium
is related to: MPIDB
is related to: TissueNet - The Database of Human Tissue Protein-Protein Interactions
is related to: InteroPorc
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: NIH Data Sharing Repositories
is related to: PSICQUIC Registry
is related to: Agile Protein Interactomes DataServer
has parent organization: University of California at Los Angeles; California; USA
NIGMS PMID:14681454 Free, Available for download, Freely available OMICS_01905, nif-0000-00569, r3d100010882, biotools:dip https://dip.doe-mbi.ucla.edu/dip/Main.cgi
https://bio.tools/dip
https://doi.org/10.17616/R3431F
SCR_003167 , Database of Interacting Proteins, DIP, Database of Interacting Proteins (DIP) 2026-02-17 10:00:11 153
Piano
 
Resource Report
Resource Website
100+ mentions
Piano (RRID:SCR_003200) data analysis software, software application, data processing software, software resource Software R-package for running gene set analysis using various statistical methods, from different gene level statistics and a wide range of gene-set collections. The Piano package contains functions for combining the results of multiple runs of gene set analyses. r, omics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chalmers University of Technology; Gothenburg; Sweden
has parent organization: Bioconductor
PMID:23444143 Free, Available for download, Freely available OMICS_01558, biotools:piano https://bio.tools/piano SCR_003200 2026-02-17 10:00:13 182
Solas
 
Resource Report
Resource Website
1+ mentions
Solas (RRID:SCR_003168) software application, data processing software, data analysis software, source code, software resource, sequence analysis software Software package for the statistical language R, devoted to the analysis of next generation short read data of RNA-seq transcripts. It provides predictions of alternative exons in a single condition/cell sample, predictions of differential alternative exons between two conditions/cell samples, and quantification of alternative splice forms in a single condition/cell sample. r statistical package, rna seq, exon prediction, exon splicing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: R Project for Statistical Computing
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
Free, Available for download, Freely available biotools:solas, OMICS_01339 https://bio.tools/solas SCR_003168 2026-02-17 10:00:12 8
rDiff
 
Resource Report
Resource Website
1+ mentions
rDiff (RRID:SCR_003162) software application, data processing software, data analysis software, software resource, sequence analysis software Software tool for detecting differential RNA processing from RNA-Seq data. It implements two statistical tests, rDiff.parametric and rDiff.nonparametric, to detect changes of the RNA processing between two samples. differential rna processing, rna processing, rna seq is listed by: OMICtools PMID:23585274 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01338 SCR_003162 2026-02-17 10:00:12 6
PIRSF
 
Resource Report
Resource Website
10+ mentions
PIRSF (RRID:SCR_003352) PIRSF data or information resource, narrative resource, standard specification, database A SuperFamily classification system, with rules for functional site and protein name, to facilitate the sensible propagation and standardization of protein annotation and the systematic detection of annotation errors. The PIRSF concept is being used as a guiding principle to provide comprehensive and non-overlapping clustering of UniProtKB sequences into a hierarchical order to reflect their evolutionary relationships. The PIRSF classification system is based on whole proteins rather than on the component domains; therefore, it allows annotation of generic biochemical and specific biological functions, as well as classification of proteins without well-defined domains. There are different PIRSF classification levels. The primary level is the homeomorphic family, whose members are both homologous (evolved from a common ancestor) and homeomorphic (sharing full-length sequence similarity and a common domain architecture). At a lower level are the subfamilies which are clusters representing functional specialization and/or domain architecture variation within the family. Above the homeomorphic level there may be parent superfamilies that connect distantly related families and orphan proteins based on common domains. Because proteins can belong to more than one domain superfamily, the PIRSF structure is formally a network. The FTP site provides free download for PIRSF. protein annotation, classification, protein, superfamily, functional site, protein name, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
has parent organization: Protein Information Resource
NHGRI U01-HG02712;
NSF DBI-0138188;
NSF ITR-0205470
PMID:19455212
PMID:14681371
Free, Freely available biotools:pirsf, nif-0000-03294, OMICS_01697 https://bio.tools/pirsf http://pir.georgetown.edu/pirsf/ SCR_003352 PIR SuperFamily, Protein Information Resource SuperFamily 2026-02-17 09:59:59 28
MouseNET
 
Resource Report
Resource Website
1+ mentions
MouseNET (RRID:SCR_003357) mouseNet data or information resource, production service resource, analysis service resource, database, service resource, data analysis service A functional network for laboratory mouse based on integration of diverse genetic and genomic data. It allows the users to accurately predict novel functional assignments and network components. MouseNET uses a probabilistic Bayesian algorithm to identify genes that are most likely to be in the same pathway/functional neighborhood as your genes of interest. It then displays biological network for the resulting genes as a graph. The nodes in the graph are genes (clicking on each node will bring up SGD page for that gene) and edges are interactions (clicking on each edge will show evidence used to predict this interaction). Most likely, the first results to load on the results page will be a list of significant Gene Ontology terms. This list is calculated for the genes in the biological network created by the mouseNET algorithm. If a gene ontology term appears on this list with a low p-value, it is statistically significantly overrepresented in this biological network. The graph may be explored further. As you move the mouse over genes in the network, interactions involving these genes are highlighted.If you click on any of the highlighted interactions graph, evidence pop-up window will appear. The Evidence pop-up lists all evidence for this interaction, with links to the papers that produced this evidence - clicking these links will bring up the relevant source citation(s) in PubMed. gene, network, mouse, protein function, visualization, open reading frame, graph is listed by: OMICtools
is related to: Gene Ontology
is related to: mouseMAP
has parent organization: Princeton University; New Jersey; USA
NSF DBI-0546275;
NIGMS R01 GM071966;
NSF IIS-0513552;
NIGMS P50 GM071508
PMID:18818725 Free, Freely available OMICS_01550, nif-0000-32003 SCR_003357 MouseNET 2026-02-17 10:00:17 3
nSolver Analysis Software
 
Resource Report
Resource Website
100+ mentions
nSolver Analysis Software (RRID:SCR_003420) nSolver Analysis Software software application, data processing software, software resource Data analysis software program that offers nCounter users the ability to QC, normalize, and analyze data without having to purchase additional software packages. normalization, analysis, ncounter, os x, windows, quality control is listed by: OMICtools Restricted OMICS_02309 https://nanostring.app.box.com/v/nSolver-AdvancedAnalysis
https://nanostring.com/products/ncounter-analysis-system/ncounter-analysis-solutions/nsolver-data-analysis-support/
SCR_003420 2026-02-17 10:00:00 395
SPOT
 
Resource Report
Resource Website
100+ mentions
SPOT (RRID:SCR_005623) software application, data processing software, software resource, software toolkit, image analysis software Software package for analysis of microarray images. Microarray spot detection and characterization software package which extracts numerical information from cDNA microarrays., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. microarray, cdna microarray, cdna, image, spot detection, microarray spot detection is listed by: OMICtools
has parent organization: Macquarie University; Sydney; Australia
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00847 SCR_005623 2026-02-17 10:00:55 300
GREAT: Genomic Regions Enrichment of Annotations Tool
 
Resource Report
Resource Website
50+ mentions
GREAT: Genomic Regions Enrichment of Annotations Tool (RRID:SCR_005807) GREAT production service resource, analysis service resource, source code, service resource, software resource, data analysis service Data analysis service that predicts functions of cis-regulatory regions identified by localized measurements of DNA binding events across an entire genome. Whereas previous methods took into account only binding proximal to genes, GREAT is able to properly incorporate distal binding sites and control for false positives using a binomial test over the input genomic regions. GREAT incorporates annotations from 20 ontologies and is available as a web application. The utility of GREAT extends to data generated for transcription-associated factors, open chromatin, localized epigenomic markers and similar functional data sets, and comparative genomics sets. Platform: Online tool term enrichment, cis-regulatory region, function, gene, genomic, annotation, ontology, chromatin immunoprecipitation, sequencing, chip-seq, comparative genomics, transcription factor binding is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: PRISM (Stanford database)
is related to: Gene Ontology
has parent organization: Stanford University School of Medicine; California; USA
Bio-X ;
Howard Hughes Medical Institute ;
Stanford University; California; USA ;
Packard ;
Searle Scholar ;
Microsoft Research ;
Alfred P. Sloan Foundation ;
Edward Mallinckrodt Jr. Foundation ;
NIH ;
Human Frontier Science Program fellowship LT000896/2009-l;
NICHD 1R01HD059862;
NHGRI R01HG005058;
NSF CCF-0939370;
DFG Hi 1423/2-1
PMID:20436461
PMID:23814184
Free for academic use, Acknowledgement requested nlx_149295, OMICS_00635 SCR_005807 Genomic Regions Enrichment of Annotations Tool (GREAT), Genomic Regions Enrichment of Annotations Tool 2026-02-17 10:00:49 82
InterProScan
 
Resource Report
Resource Website
5000+ mentions
InterProScan (RRID:SCR_005829) data access protocol, software application, production service resource, data processing software, data analysis software, analysis service resource, service resource, software resource, web service, data analysis service Software package for functional analysis of sequences by classifying them into families and predicting presence of domains and sites. Scans sequences against InterPro's signatures. Characterizes nucleotide or protein function by matching it with models from several different databases. Used in large scale analysis of whole proteomes, genomes and metagenomes. Available as Web based version and standalone Perl version and SOAP Web Service. functional, analysis, sequence, protein, nucleotide, predict, presence, domain, site, proteome, genome, metagenome, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Gene Ontology
is related to: RARTF
is related to: InterPro
is related to: LegumeIP
is related to: UniProtKB
has parent organization: European Bioinformatics Institute
European Union ;
Biotechnology and Biological Sciences Research Council ;
EMBL
PMID:15980438
PMID:17202162
PMID:24451626
Free, Available for download, Freely available OMICS_01479, biotools:interproscan_4, nlx_149337 https://www.ebi.ac.uk/interpro/download.html
https://bio.tools/interproscan_4
SCR_005829 InterProScan Sequence Search, InterProScan 2, InterProScan 3, InterProScan 4, InterProScan 5 2026-02-17 10:00:40 6936

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