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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.molbio1.princeton.edu/macro/
Facility helps with structure determination and analysis on service basis, but also encourages users with prior experience to use facilities independently. Offers services for setting up crystallization trials, x-ray data collection, structure determination and structure analysis. Assists in interpretation of existing structures available in Protein Data Bank and assists in homology modeling.
Proper citation: Princeton University Macromolecular Crystallography Core Facility (RRID:SCR_017833) Copy
http://www.biotech.wisc.edu/facilities/brc/home
Facility within UW Biotechnology Center (UWBC) for assisting researchers with their data analysis needs. Helps with variety of common sequencing related projects, DNA-seq, ChIP-Seq, RNA-Seq, 16S metagenomics, and small RNA analyses.
Proper citation: Wisconsin-Madison University Biotechnology Center Bioinformatics Resource Center Core Facility (RRID:SCR_017799) Copy
http://sites.northwestern.edu/htal/
Core provides expertise and resources for large scale biology. Helps to set up, run, gather data and perform analysis in drug discovery research, biochemistry, cell and organismal biology, functional genomic screening, and synthetic genetic. Works with proteins, nucleic acids, small model organisms, and microbial strains. Provides tissue culture,produces and uses lentivirus particles, screens compound libraries, does experiments for investigators,generates preliminary data to figure out if idea is workable, discusses project development. Services include Macromolecular binding, biochemical, and cell-based assays,High content screening with widefield or confocal optics,Nanoliter liquid handling up to 1536-well density,Whole-plate kinetic assays (ion currents, GPCR signaling),Compound library screening,CRISPR/Cas9 screening (multiplexed libraries),Analysis of large data sets,Fluorescence Thermal Shift assay (measures protein melting),Complex liquid handling work flows.
Proper citation: Northwestern University High Throughput Analysis Laboratory Core Facility (RRID:SCR_017879) Copy
Core provides access to NMR technology. Users can collect their own data, facility staff can do it all for you, or collaborative projects can be developed. Provides training in instrument operation and can offer advice for data analysis or project feasibility. Facility houses two 600 MHz Bruker Avance III spectrometers with cryogenically cooled probes.
Proper citation: University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences NMR Core Facility (RRID:SCR_017919) Copy
https://isairr.bsd.uchicago.edu/
Core offers imaging modalities, techniques, and services for in vivo imaging of small animals and ex vivo imaging of tissue/organ specimens. iSAIRR sub-cores feature magnetic resonance imaging and spectroscopy (MRIS); optical imaging (bioluminescence and fluorescence); positron emission tomography, single photon emission computed tomography, and computed tomography (PET/SPECT/CT).Services include Assistance with experimental design,Assisted and/or independent image acquisition,Veterinary support for all imaging modalities,Assistance with data processing and interpretation.
Proper citation: Chicago University Integrated Small Animal Imaging Research Resource Core Facility (RRID:SCR_017923) Copy
https://devsci.northwestern.edu/neurodevelopmental-resource-core-services/
Core provides services in support of research, education, and assessment technology related to neurodevelopmental research methods. Services include Scientific Consultation, Workshops and Training,EEG/ERP,Eye-tracking,Clinical and Behavioral Measure Services.Services include Data Collection, Use of Equipment, Experimental Task Creation and Preparation.
Proper citation: Northwestern University DevSci Neurodevelopmental Core Facility (RRID:SCR_017957) Copy
https://fralinlifesci.vt.edu/core-services/mass-spectrometry-incubator.html
Facility supports Virginia Tech's research infrastructure as mass spectrometry analysis and education center. Provides training in sample preparation, instrument operation and data analysis, with strong emphasis on metadata and analytical requirements for publication of metabolomic and proteomic results.
Proper citation: Virginia Tech Mass Spectrometry Incubator Core Facility (RRID:SCR_017956) Copy
Core facility for genomics research offers range of DNA sequencing, assistance and advising in planning, data acquisition, and data analysis. Provides genetic and genomic support to environmental and biomedical research projects. Creates education and training opportunities for students and professionals.
Proper citation: Northern Arizona University Environmental Genetics and Genomics Laboratory (RRID:SCR_017939) Copy
https://labs.gladstone.org/histology/index.html
Core provides technical assistance, training, consultation and assistance with all aspects of experimental design, sample preparation, image processing, and data analysis to scientists from Gladstone, UCSF, and Bay Area scientific community. Core is equipped with expertise in histological techniques including complex immunolabeling and histological image analysis, high-resolution imaging, confocal microscopy, light-sheet microscopy, spinning disk microscopy, and optical projection tomography and advanced image analysis.Histology Services includeTissue dissection and fixation, Paraffin processing and embedding,Frozen (cryo) processing and embedding,Tissue sectioning,Section staining.Microscopy Services include Epifluorescence, confocal and light sheet microscopy,Whole slide scanning,Microscopy consultation and training,Digital image analysis.
Proper citation: Gladstone Institutes Histology and Light Microscopy Core Facility (RRID:SCR_017940) Copy
Core provides statistical and big data analysis support. Performs data analysis and manuscript preparation services in Biostatistics, such as statistical genetics, longitudinal, survival, and high-throughput/high-dimensional omics data analysis; and Bioinformatics, such as DNA- and RNA-seq alignment, single cell DNA- and RNA-seq analysis, variant calling, differential expression and pathway analysis, data integration, online data submission, and custom script writing. Provides training to lab staff to enable them to perform future analyses.
Proper citation: Oregon Health and Science University Bioinformatics and Biostatistics Core Facility (RRID:SCR_017946) Copy
http://www.marmosetbrain.org/nencki_monash_template
Open access template of young adult marmoset brain, created from three dimensional reconstructions. Histology based average template of marmoset cortex with probabilistic localization of cytoarchitectural areas. Allows direct estimates of most likely coordinates of each cortical area, as well as quantification of margins of error involved in assigning voxels to areas, and preserves quantitative information about laminar structure of cortex.Enables integration with magnetic resonance imaging and tracer based connectivity data. Allows interoperability between NM template and other current digital atlases of marmoset cortex.
Proper citation: Nencki-Monash template (RRID:SCR_018367) Copy
https://www.bioinformatics.com.cn/SRplot
Web server that integrated data visualization and graphing functions together. Can be run easily with all Web browsers, with user-friendly graphical interface, users can paste your data directly into input box according to defined file format. Resulting graphs can be downloaded in bitmap (PNG or TIFF) or vector (PDF or SVG) format in publication quality. Used for data visualization and graphing.
Proper citation: SRplot (RRID:SCR_025904) Copy
Platform for data and statistics. Website provides data-driven services, collection of statistics, reports, and insights on over 80,000 topics.
Proper citation: statista (RRID:SCR_026121) Copy
https://www.mammaldiversity.org/
Updatable online database of mammal taxonomic and biodiversity information hosted by American Society of Mammalogists. Provides information on species-level and higher taxonomic changes, thereby promoting more rigorous study of mammalian biodiversity worldwide. The initial objective has been to aggregate, curate, and compile, new citations on species descriptions and taxonomic revisions into regular releases that are downloadable in comma-delimited format. Downstream goals include expanded hosting of ecological, trait, and taxonomic data.
Proper citation: Mammal Diversity Database (RRID:SCR_026173) Copy
https://github.com/nf-core/rnaseq
Software RNA sequencing analysis pipeline using STAR, RSEM, HISAT2 or Salmon with gene/isoform counts and extensive quality control. Can be used to analyse RNA sequencing data obtained from organisms with reference genome and annotation. It takes a samplesheet and FASTQ files as input, performs quality control (QC), trimming and (pseudo-)alignment, and produces a gene expression matrix QC report.
Proper citation: rnaseq (RRID:SCR_026973) Copy
Cultivarium creates tools for life scientists to expand access to novel microorganisms, inspire new research avenues, and push the frontiers of biotechnology. Aggregates information, data, and publications for bacteria, fungi, archaea, and protists.
Proper citation: Cultivarium (RRID:SCR_027163) Copy
Open data repository to facilitate research on the relationship between neighborhoods and health, especially within the context of large federally funded surveys and cohort studies. Used to explore topics of interest to neighborhoods and communities. NaNDA measures can be readily linked to survey data, cohort studies, electronic medical records, or other microdata, via geographic identifiers, or combined and explored on their own. NaNDA datasets are created by researchers in the Social Environment and Health program at the University of Michigan Institute for Social Research.
Proper citation: National Neighborhood Data Archive (RRID:SCR_027451) Copy
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