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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
DEXSeq
 
Resource Report
Resource Website
100+ mentions
DEXSeq (RRID:SCR_012823) DEXSeq software resource Software package focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
OMICS_01329, biotools:dexseq https://bio.tools/dexseq SCR_012823 2026-02-07 02:08:44 488
DNaseR
 
Resource Report
Resource Website
DNaseR (RRID:SCR_012819) DNaseR software resource A R package that enables the identification of protein binding footprints in DNase I hypersensitive sites sequencing (DNase-seq) data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:23118738 Free biotools:dnaser, OMICS_00517 https://bio.tools/dnaser SCR_012819 DNaseR: DNase I footprinting analysis of DNase-seq data 2026-02-07 02:08:38 0
charm
 
Resource Report
Resource Website
50+ mentions
charm (RRID:SCR_012992) charm software resource Software package that implements analysis tools for DNA methylation data generated using Nimblegen microarrays and the McrBC protocol. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
biotools:charm, OMICS_00792 https://bio.tools/charm SCR_012992 2026-02-07 02:08:38 63
Trinity
 
Resource Report
Resource Website
5000+ mentions
Trinity (RRID:SCR_013048) Trinity software resource Software for the efficient and robust de novo reconstruction of transcriptomes from RNA-seq data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Broad Institute
has parent organization: Hebrew University of Jerusalem; Jerusalem; Israel
DOI:10.1038/nbt.1883 biotools:trinity, OMICS_01327 https://bio.tools/trinity
https://sources.debian.org/src/trinityrnaseq/
SCR_013048 2026-02-07 02:08:41 9358
MethylCoder
 
Resource Report
Resource Website
1+ mentions
MethylCoder (RRID:SCR_012997) MethylCoder software resource A single program that takes of bisulfite-treated reads and outputs per-base methylation data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21724594 biotools:methylcoder, OMICS_00585 https://bio.tools/methylcoder SCR_012997 2026-02-07 02:08:39 4
GENE-counter
 
Resource Report
Resource Website
1+ mentions
GENE-counter (RRID:SCR_013056) GENE-counter software resource A computational pipeline for analyzing RNA-Sequencing (RNA-Seq) data for differential gene expression of eukaryotes, prokaryotes, as well as organisms with no available genome reference sequence. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21998647 OMICS_01404, biotools:gene-counter https://bio.tools/gene-counter SCR_013056 2026-02-07 02:08:41 7
CloudAligner
 
Resource Report
Resource Website
1+ mentions
CloudAligner (RRID:SCR_012962) CloudAligner software resource A map/reduce based application for mapping short reads generated by the next-generation sequencing machines. matlab, mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21645377 GNU General Public License, v3 OMICS_00656, biotools:cloudaligner https://bio.tools/cloudaligner SCR_012962 2026-02-07 02:08:38 4
seqMINER
 
Resource Report
Resource Website
100+ mentions
seqMINER (RRID:SCR_013020) seqMINER software resource Software for a genome wide mapping data interpretation platform for NGS (ChIPSeq). java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21177645 GNU General Public License, v3 biotools:seqminer, OMICS_00460 https://bio.tools/seqminer SCR_013020 2026-02-07 02:08:40 187
cn.mops
 
Resource Report
Resource Website
10+ mentions
cn.mops (RRID:SCR_013036) cn.mops software resource A data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
biotools:cn.mops, OMICS_00335 https://bio.tools/cn.mops SCR_013036 Copy Number estimation by a Mixture Of PoissonS 2026-02-07 02:08:40 10
SAMMate
 
Resource Report
Resource Website
10+ mentions
SAMMate (RRID:SCR_013037) SAMMate software resource An open source GUI software suite to process RNA-Seq data. It is composed of two modules: assemblySAM and SAMMate. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
biotools:sammate, OMICS_01264 https://bio.tools/sammate SCR_013037 2026-02-07 02:08:55 11
Flexbar
 
Resource Report
Resource Website
100+ mentions
Flexbar (RRID:SCR_013001) Flexbar software resource Flexible barcode and adapter removal for sequencing platforms. bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.3390/biology1030895 biotools:flexbar https://bio.tools/flexbar
https://sources.debian.org/src/flexbar/
SCR_013001 2026-02-07 02:08:39 274
LOCAS
 
Resource Report
Resource Website
1+ mentions
LOCAS (RRID:SCR_013064) LOCAS software resource A software to assemble short reads of next generation sequencing technologies at low coverage. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21858125 OMICS_00019, biotools:locas https://bio.tools/locas SCR_013064 2026-02-07 02:08:42 2
PRICE
 
Resource Report
Resource Website
100+ mentions
PRICE (RRID:SCR_013063) PRICE software resource Software for a de novo genome assembler implemented in C++. c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at San Francisco; California; USA
OMICS_01430, biotools:price https://bio.tools/price SCR_013063 Paired-Read Iterative Contig Extension 2026-02-07 02:08:41 160
QCGWAS
 
Resource Report
Resource Website
1+ mentions
QCGWAS (RRID:SCR_006408) QCGWAS software resource Software tools for (automated and manual) quality control of the results of Genome Wide Association Studies. quality control, genome wide association study, windows, os x, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24395754 GNU General Public License, v3 or later OMICS_02203, biotools:qcgwas https://bio.tools/qcgwas SCR_006408 QCGWAS: Quality Control of Genome Wide Association Study results, Quality Control of Genome Wide Association Study 2026-02-07 02:07:29 7
Jalview
 
Resource Report
Resource Website
1000+ mentions
Jalview (RRID:SCR_006459) Jalview software resource A free program for multiple sequence alignment editing, visualisation and analysis that is available in two forms: a lightweight Java applet for use in web applications, and a powerful desktop application that employs web services for sequence alignment, secondary structure prediction and the retrieval of alignments, sequences, annotation and structures from public databases and any DAS 1.53 compliant sequence or annotation server. Use it to view and edit sequence alignments, analyse them with phylogenetic trees and principal components analysis (PCA) plots and explore molecular structures and annotation. Jalview has built in DNA, RNA and protein sequence and structure visualisation and analysis capabilities. It uses Jmol to view 3D structures, and VARNA to display RNA secondary structure. edit, analysis, annotation, multiple sequence alignment, wysiwyg, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Dundee; Scotland; United Kingdom
BBSRC BBSB16542 PMID:19151095
DOI:10.1093/bioinformatics/btp033
GNU General Public License, v3, Acknowledgement requested OMICS_00885, biotools:Jalview https://bio.tools/Jalview
https://sources.debian.org/src/jalview/
SCR_006459 2026-02-07 02:07:30 3621
SRAdb
 
Resource Report
Resource Website
10+ mentions
SRAdb (RRID:SCR_006524) SRAdb software resource Software package to make access to the compilation of metadata from NCBI SRA and tools associated with submission, study, sample, experiment and run much more feasible. This is accomplished by parsing all the NCBI SRA metadata into a SQLite database that can be stored and queried locally. Fulltext search in the package make querying metadata very flexible and powerful. fastq and sra files can be downloaded for doing alignment locally. Beside ftp protocol, the SRAdb has funcitons supporting fastp protocol (ascp from Aspera Connect) for faster downloading large data files over long distance. The SQLite database is updated regularly as new data is added to SRA and can be downloaded at will for the most up-to-date metadata. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI Sequence Read Archive (SRA)
has parent organization: Bioconductor
PMID:23323543 Artistic License, v2 biotools:sradb, OMICS_01032 https://bio.tools/sradb SCR_006524 SRAdb - A compilation of metadata from NCBI SRA and tools 2026-02-07 02:07:17 18
NCBI
 
Resource Report
Resource Website
10000+ mentions
NCBI (RRID:SCR_006472) NCBI nonprofit organization A portal to biomedical and genomic information. NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information for the better understanding of molecular processes affecting human health and disease. biomedical, genomic, molecular biology, health, disease, database, computational biology, bio.tools is used by: NIF Data Federation
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: NCBI Viral Genomes
is related to: Clone DB
is related to: PubReader
is related to: OMIA - Online Mendelian Inheritance in Animals
is related to: European Nucleotide Archive (ENA)
is related to: Plant Co-expression Annotation Resource
is related to: METAGENOTE
is related to: Phyutility
is related to: CaspBase
is related to: Prokaryotic Genomes Automatic Annotation Pipeline
has parent organization: National Library of Medicine
is parent organization of: MedGen
is parent organization of: dbSTS
is parent organization of: PubMed Health
is parent organization of: BLASTP
is parent organization of: GQuery
is parent organization of: BLASTN
is parent organization of: GTEx eQTL Browser
is parent organization of: BLASTX
is parent organization of: Homology Maps Page
is parent organization of: PEDHUNTER
is parent organization of: Conserved Domain Database
is parent organization of: NCBI Genome Survey Sequences Database
is parent organization of: High Throughput Genomic Sequences Division
is parent organization of: AceView
is parent organization of: dbMHC
is parent organization of: dbSNP
is parent organization of: Entrez Gene
is parent organization of: NCBI Genome
is parent organization of: NCBI database of Genotypes and Phenotypes (dbGap)
is parent organization of: GenBank
is parent organization of: International HapMap Project
is parent organization of: IgBLAST
is parent organization of: Lowes Syndrome Mutation Database
is parent organization of: HomoloGene
is parent organization of: Influenza Virus Resource
is parent organization of: Distant Regulatory Elements
is parent organization of: e-PCR
is parent organization of: MapViewer
is parent organization of: Primer-BLAST
is parent organization of: dbVar
is parent organization of: NCBI Taxonomy
is parent organization of: NCBI Protein Database
is parent organization of: Gene Reference into Function
is parent organization of: Protein Clusters
is parent organization of: RefSeq
is parent organization of: TPA
is parent organization of: GENSAT at NCBI - Gene Expression Nervous System Atlas
is parent organization of: COBALT: Constraint-based Multiple Alignment Tool
is parent organization of: PubMed Central
is parent organization of: UniLib
is parent organization of: NCBI Structure
is parent organization of: PubChem
is parent organization of: Anopheles gambiae (African malaria mosquito) genome view
is parent organization of: UniGene
is parent organization of: NLM Catalog
is parent organization of: Entrez GEO Profiles
is parent organization of: Nucleotide database
is parent organization of: NCBI BioSystems Database
is parent organization of: CBLAST
is parent organization of: NCBI BioProject
is parent organization of: NCBI Probe
is parent organization of: PubMed
is parent organization of: NCBI BioSample
is parent organization of: NCBI Nucleotide
is parent organization of: NCBI Structure: Cn3D
is parent organization of: NCBI BLAST
is parent organization of: IBIS: Inferred Biomolecular Interactions Server
is parent organization of: NCBI Sequence Read Archive (SRA)
is parent organization of: Gene Expression Omnibus (GEO)
is parent organization of: NCBI Popset
is parent organization of: PIE the search
is parent organization of: Genetic Testing Registry
is parent organization of: NCBI Resource List
is parent organization of: NCBI dbRBC
is parent organization of: NCBI YouTube Channel
is parent organization of: NCBI Epigenomics
is parent organization of: ClinVar
is parent organization of: Genome Reference Consortium
is parent organization of: GeneReviews
is parent organization of: Molecular Imaging and Contrast Agent Database
is parent organization of: Consensus CDS
is parent organization of: UniSTS
is parent organization of: HIV-1 Human Protein Interaction Database
is parent organization of: Assay Guidance Manual
is parent organization of: Bookshelf
is parent organization of: COG
is parent organization of: Gene Expression Omnibus
is parent organization of: Molecular Modelling DataBase
is parent organization of: Organelle Genome Resources
is parent organization of: SKY/M-FISH/CGH
is parent organization of: dbEST
is parent organization of: JournalReview.org
is parent organization of: NCBI GenBank via FTP
is parent organization of: PubChem Compound
is parent organization of: Molecular Modeling DataBase
is parent organization of: Vector Alignment Search Tool
is parent organization of: PubChem BioAssay
is parent organization of: NCBI Genome Workbench
is parent organization of: TBLASTN
is parent organization of: TBLASTX
is parent organization of: Mega BLAST
is parent organization of: Genetic Codes
is parent organization of: HIV-1, Human Protein Interaction Database
is parent organization of: PubReader
is parent organization of: PubChem Substance
is parent organization of: OMIA - Online Mendelian Inheritance in Animals
is parent organization of: OMIM
is parent organization of: 1000 Genomes: A Deep Catalog of Human Genetic Variation
is parent organization of: GeneTests
is parent organization of: NCBI Genome Survey Sequences Database
is parent organization of: MagicBlast
is parent organization of: RefSeq
is parent organization of: Sequin
is parent organization of: Batch Entrez
is parent organization of: Entrez
is parent organization of: tbl2asn
is parent organization of: Whole Genome Shotgun (WGS) Project
is parent organization of: Digital Differential Display (DDD)
is parent organization of: BLASTClust
is parent organization of: PASC
is parent organization of: Open Reading Frame Finder
is parent organization of: Genotyping
works with: Human Mouse Disease Connection
works with: A plasmid Editor
works with: Database of genes related to Repeat Expansion Diseases
Public, The community can contribute to this resource nif-0000-00139, biotools:ncbi_resources https://bio.tools/ncbi_resources http://www.ncbi.nih.gov/ SCR_006472 National Center for Biotechnology Information, NCBI - National Center for Biotechnology Information 2026-02-07 02:07:30 25407
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-02-07 02:07:32 145
SpliceTrap
 
Resource Report
Resource Website
10+ mentions
SpliceTrap (RRID:SCR_006728) SpliceTrap software resource A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Cold Spring Harbor Laboratory
PMID:21896509 biotools:splicetrap, OMICS_01292 https://bio.tools/splicetrap SCR_006728 2026-02-07 02:07:15 16
BEDTools
 
Resource Report
Resource Website
5000+ mentions
BEDTools (RRID:SCR_006646) BEDTools software resource A powerful toolset for genome arithmetic allowing one to address common genomics tasks such as finding feature overlaps and computing coverage. Bedtools allows one to intersect, merge, count, complement, and shuffle genomic intervals from multiple files in widely-used genomic file formats such as BAM, BED, GFF/GTF, VCF. While each individual tool is designed to do a relatively simple task (e.g., intersect two interval files), quite sophisticated analyses can be conducted by combining multiple bedtools operations on the UNIX command line. genomics, bed, sam, bam, overlap, sequencing, intersect, coverage, gff, vcf, bedgraph, interval, genome arithmetic, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Hydra
is related to: pybedtools
is required by: SL-quant
PMID:20110278
DOI:10.1093/bioinformatics/btq033
GNU General Public License, v2, Acknowledgement requested OMICS_01159, biotools:bedtools https://code.google.com/p/bedtools/
https://bio.tools/bedtools
https://sources.debian.org/src/bedtools/
SCR_006646 bedtools - a swiss army knife for genome arithmetic, bedtools: a flexible suite of utilities for comparing genomic features 2026-02-07 02:07:21 9915

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