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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Supplies biomedical investigators with rat models, embryonic stem cells, related reagents, and protocols they require for their research. In addition to repository, cryostorage and distribution functions, RRRC can facilitate acquisition of rat strains from other international repositories as well as provide consultation and technical training to investigators using rat models.
Proper citation: Rat Resource and Research Center (RRID:SCR_002044) Copy
http://learn.genetics.utah.edu/
Educational resources that provide accurate and unbiased information about topics in genetics, bioscience and health for global and local audiences. They are jargon-free, target multiple learning styles, and often convey concepts through animation and interactivity. The Genetic Science Learning Center is a science and health education program located in the midst of the bioscience research being carried out at the University of Utah. Our mission is making science easy for everyone to understand. * Two websites, available free of charge to Internet users worldwide: ** Learn.Genetics delivers educational materials on genetics, bioscience and health topics. They are designed to be used by students, teachers and members of the public. The materials meet selected US education standards for science and health. ** Teach.Genetics provides resources for K-12 teachers, higher education faculty, and public educators. These include PDF-based Print-and-Go™ activities, unit plans and other supporting resources. The materials are designed to support and extend the materials on Learn.Genetics. *Professional development programs that update K-16 teachers' expertise in bioscience and health topics as well as prepare them to implement the materials on our websites. * Community programs that engage with diverse communities in discussions about genetics and health, and in developing culturally and linguistically-appropriate educational materials. Some topics in genetics and bioscience research are controversial. The Center does not take sides in political or ethical controversies. Rather, our goal is to provide comprehensive information that promotes a lively discussion of these topics, so that individuals can arrive at their own informed decisions.
Proper citation: University of Utah Genetic Science Learning Center - Learn Genetics (RRID:SCR_001910) Copy
Center for advancing scientific understanding and improving the health and well-being of humans and nonhuman primates. The Center conducts research in microbiology and immunology, neurologic diseases, neuropharmacology, behavioral, cognitive and developmental neuroscience, and psychiatric disorders.
Proper citation: Yerkes National Primate Research Center (RRID:SCR_001914) Copy
https://github.com/aidenlab/juicer.git
Software platform for analyzing kilobase resolution Hi-C data. Open source tool for analyzing terabase scale Hi-C datasets. Allowes to transform raw sequence data into normalized contact maps.
Proper citation: Juicer (RRID:SCR_017226) Copy
https://amp.pharm.mssm.edu/geneshot/
Software tool as search engine for ranking genes from arbitrary text queries. Enables to enter arbitrary search terms, to receive ranked lists of genes relevant to search terms. Returned ranked gene lists contain genes that were previously published in association with search terms, as well as genes predicted to be associated with terms based on data integration from multiple sources. Search results are presented with interactive visualizations.
Proper citation: Geneshot (RRID:SCR_017582) Copy
http://fit.genomics.lbl.gov/cgi-bin/myFrontPage.cgi
Web tool for browsing genome wide fitness experiments for diverse bacteria from Deutschbauer lab, the Arkin lab, and collaborators. Collection of mutant phenotypes for bacterial genes of unknown function.
Proper citation: Fitness Browser (RRID:SCR_018981) Copy
https://github.com/Cai-Lab-at-University-of-Michigan/nTracer
Software tool as plug-in for ImageJ software. Used for tracing microscopic images.
Proper citation: nTracer (RRID:SCR_023032) Copy
https://maayanlab.cloud/chea3/
Web based transcription factor enrichment analysis. Web server ranks TFs associated with user-submitted gene sets. ChEA3 background database contains collection of gene set libraries generated from multiple sources including TF-gene co-expression from RNA-seq studies, TF-target associations from ChIP-seq experiments, and TF-gene co-occurrence computed from crowd-submitted gene lists. Enrichment results from these distinct sources are integrated to generate composite rank that improves prediction of correct upstream TF compared to ranks produced by individual libraries.
Proper citation: ChIP-X Enrichment Analysis 3 (RRID:SCR_023159) Copy
Web server application that infers overrepresentation of upstream kinases whose putative substrates are in user inputted list of proteins. Used to analyze data from phosphoproteomics and proteomics studies to predict upstream kinases responsible for observed differential phosphorylations.
Proper citation: Kinase Enrichment Analysis 3 (RRID:SCR_023623) Copy
https://generanger.maayanlab.cloud/gene/A2M?database=ARCHS4
Web server application that provides access to processed data about expression of human genes and proteins across human cell types, tissues, and cell lines from several atlases. Used to explore single gene expression across tissues and cell types.
Proper citation: GeneRanger (RRID:SCR_023622) Copy
https://targetranger.maayanlab.cloud/
Web server application that identifies targets from user inputted RNA-seq samples collected from cells we wish to target. By comparing inputted samples with processed RNA-seq and proteomics data from several atlases, TargetRanger identifies genes that are highly expressed in target cells while lowly expressed across normal human cell types, tissues, and cell lines.
Proper citation: TargetRanger (RRID:SCR_023621) Copy
http://www.nsrrc.missouri.edu/
Provides access to critically needed swine models of human health and disease as well as a central resource for reagents, creation of new genetically modified swine, and information and training related to use of swine models in biomedical research.
Proper citation: National Swine Resource and Research Center (RRID:SCR_006855) Copy
http://crispr-era.stanford.edu/index.jsp
Software comprehensive design tool for CRISPR mediated gene editing, repression and activation. Fast and comprehensive guide RNA design tool for genome editing, repression and activation. Used for automated genome wide sgRNA design.
Proper citation: CRISPR-ERA (RRID:SCR_018710) Copy
Web tool to search multiple public variant databases simultaneously and provide a unified interface to facilitate the search process. Used for integration of human and model organism genetic resources to facilitate functional annotation of the human genome. Used for analysis of human genes and variants by cross-disciplinary integration of records available in public databases to facilitate clinical diagnosis and basic research.
Proper citation: MARRVEL (RRID:SCR_016871) Copy
http://upr.eagle-i.net/i/0000012c-9dd1-fddf-95a5-371e80000000
Core facility that provides the following services: Necropsy. The Sabana Seca Field Station (SSFS) is the administrative headquarters for the Caribbean Primate Research Center, or CPRC. This area contains offices, a clinic, and laboratories for reproductive biology and bone densitometry, necropsy and maintenance buildings. It houses rhesus monkeys from the CS colony or from the CS genetic line.
Proper citation: UPR Sabana Seca Field Station Caribbean Primate Research Center (RRID:SCR_010134) Copy
https://masst.gnps2.org/microbemasst/
Web taxonomically informed mass spectrometry search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging database of over 60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns.
Proper citation: microbeMASST (RRID:SCR_024713) Copy
https://dgrc.bio.indiana.edu/Home
Serves Drosophila research community by collecting and distributing DNA clones and vectors; collecting and distributing Drosophila cell lines; developing and testing genomics technologies for use in Drosophila and assisting members of the research community in their use.
Proper citation: Drosophila Genomics Resource Center (RRID:SCR_002845) Copy
https://www.tamuk.edu/agriculture/institutes-and-other-units/nntrc/Products-Services.html
Center to provide global research, training, and resources that will lead to the discovery of medically important toxins found in venoms. The Viper Resource Center (VRC) is located in the Natural Toxins Research Center at Texas A&M University-Kingsville.
Proper citation: National Natural Toxins Research Center (RRID:SCR_002824) Copy
Center for mutant mouse research and distribution. The objectives of the JAX MMRRC are to: identify and evaluate biomedically-significant mice, import/acquire and archive mouse strains, distribute mouse strains, and operate a control program to ensure genetic stability.
Proper citation: Mutant Mouse Resource and Research Center - Jackson Laboratory (RRID:SCR_016446) Copy
https://www.med.unc.edu/mmrrc/
Center that is a mouse cryoarchive and distribution center, which incorporates research goals that synergize with and extend the value of the resource. The goals of the UNC Chapel Hill center are to streamline and improve operating procedures, establish a comprehensive cryoarchive, develop and disseminate computational tools for mouse genotyping, and examine the effect of paternal age and epigenetics on mutation rate.
Proper citation: Mutant Mouse Resource and Research Center - University of North Carolina (RRID:SCR_016449) Copy
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