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https://joslinresearch.org/drc-cores/Advanced-Microscopy-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for performing specific morphological procedures, providing training and access to equipment, maintaining the specialized microscopes, and giving advice and interpretation.

Proper citation: Joslin Diabetes Center Advanced Microscopy Core Facility (RRID:SCR_009875) Copy   

•   Source: SciCrunch Registry

http://hunter-cuny.eagle-i.net/i/00000136-a791-3ad9-949b-425080000000

Core facility that provides the following services: Single-crystal X-ray analysis. The mission of the CUNY X-ray Diffraction (X-ray) Facility is to perform single-crystal analyses for the structure determination of molecules, which make up a crystal. This technique is called single-crystal X-ray crystallography. It is the ultimate method for definitive determination of molecular structures at the atomic level for both organic and inorganic compounds. Its uses range from simple identification of compounds to various exotic configuration and conformational studies.

Proper citation: Hunter X-ray Diffraction Facility (RRID:SCR_009872) Copy   

•   Source: SciCrunch Registry

https://joslinresearch.org/drc-cores/Advanced-Genomics-and-Genetics-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for genetic and genomic analysis, including DNA extraction from blood, access to DNA collections from the Core?s repository, SNP genotyping, and support for gene expression studies based on both high-density oligonucleotide arrays and real-time quantitative PCR.

Proper citation: Joslin Diabetes Center Advanced Genomics and Genetics Core Facility (RRID:SCR_009873) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000135-5958-291c-bf4c-ca4080000000

Howard Nanoscale Science and Engineering Facility (HNF) occupies a specially renovated wing on the first floor of the Engineering Building.The five large laboratories cover ~6000 sq. ft. of space and the HNF has about 2000 sq ft of contiguous office space. The HNF is an established centralized user facility containing over $17M of micro- and nano fabrication and characterization equipment, accessible by external and internal academic, government and industrial users. Currently, HNF has integrated facilities in the following categories: Lithography Facilities Nanofabrication Facilities Plasma Etching / Deposition Facilities CVD Deposition Facilities (SiC,GaN) Nanomembrane Facilities Characterization Facilities Computer Facilities Societal and Ethical Issues

Proper citation: Howard Nanoscale Science and Engineering Facility (RRID:SCR_009867) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000135-589a-a87e-bf4c-ca4080000000

Core facility that provides the following services: Equipment access, Training on proteomics equipment. Mission: To use mass spectrometry for studies of infectious and chronic diseases and to promote and facilitate biomedical and translational research at Howard University Objectives: To provide modern analytical instrumentation, technical expertise and essential services for biomolecular analysis To provide a broader training experience for students and faculty in biomolecular analysis through methodology- centered seminars, workshops, mini-courses, and internships To foster new multidisciplinary research collaborations using modern Proteomics technology The RCMI Proteomics Core Facility runs several research projects and provides collaborative consolidation of instrumentation, technical expertise, and support personnel to enhance the impact and availability of Mass Spectrometry and other analytical techniques for biological and biomedical science community at Howard University

Proper citation: Howard RCMI Proteomics Facility (RRID:SCR_009868) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000134-aa20-c323-bf4c-ca4080000000

Core facility that provides the following services: SNP detection service, DNA sequencing service, EBV cell transformation service, DNA sequencer access. The molecular genetics research interests are in human population genetics, anthropological genetics, immunogenetics, and the genetics of complex diseases. Ultimate goals surround elucidating questions of human variation, the evolutionary history of genes within populations and how these gene histories are involved in the etiology of complex diseases. While the laboratory''s research goals have shared consequences for all humanity, specific interests focus on populations of African ancestry. Operational Objectives: 1. Develop a SNP database for mapping functional mutations linked to diseases common in African peoples. 2. Utilization of evolutionary history of candidate genes to identify polymorphisms that are associated with diseases. 3. Exploit the linkage disquilibrium generated by admixture in the African American population for gene mapping.

Proper citation: Howard Molecular Genetics Core (RRID:SCR_009865) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-496b-76ed-eb5b-b63c80000000

Core facility that provides the following services: Informatics consultative support. The staff of this core gives guidance and/or coordinates data management, capture and analysis on behalf of the investigator within the Institute and assists more broadly with computing issues related to the approved protocol. This core provides services to investigators for their Clinical and Translational Research Center (CTRC)-approved studies that are utilizing other CTRC core services.

Proper citation: Penn/CHOP CTRC Informatics Services Core (RRID:SCR_009866) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000134-a996-f935-bf4c-ca4080000000

The Biostatistics Core is a resource for Howard University Cancer Center (HUCC) that provides statistical and computer/data management support services to affiliated members. Members of the Biostatistics Core provide advice in matters of design, randomization, power analysis, data processing, quality control, database development and management and statistical analysis in clinical and population based studies. The Biostatistics Core aims at excellence in biostatistical and methodological issues related to cancer studies and to advocate proper use of statistics, data monitoring and data analysis.

Proper citation: Howard Biostatistics Core (RRID:SCR_009863) Copy   

•   Source: SciCrunch Registry

http://howard.eagle-i.net/i/00000134-a517-7b98-bf4c-ca4080000000

Core facility that provides the following services: Access to clinical physiology equipment. The Biobehavioral Core Laboratory houses the facilities for clinical exercise physiology and psycho-physiological research. The Clinical Exercise Physiology Research facility is equipped with a Cosmed Quark b2 metabolic cart and Cosmed electrocardiogram (ECG) equipment that is programmed into a Burdick Treadmill. This is used for performing graded exercise tests to assess risk for cardiovascular disease and functional work capacity training. An Ergoline 500 medical ergometer is used for exercise testing when a cycle ergometer is needed. In addition, the laboratory has 3 other treadmills that are used exercise intervention training programs. The Psychophysiology component consists of 3 computers (Dell Desktop Pentium 4, Gateway Pentium 4, and Toshiba Portege Tablet PC Pentium III). One desktop is used for data acquisition, one for data analysis and the third for internet usage. There is a surveillance camera (Security Labs) that is used to monitor participants as they take part in study tasks. To collect impedance cardiograph data, the HIC-2002 Impedance Cardiograph is used along with the COP ?Win 5.10 USB version cardiac output program for windows. This equipment is designed to measure a variety of cardiovascular measures (heart rate, stroke volume, cardiac output, pre-ejection period, left ventricular ejection time, total ejection period, and heather index). The Dinamap Vital Signs Monitor (Model 1846 SX) is used to assess systolic blood pressure and diastolic blood pressure. Lastly, a number of psychological tasks are also included in the lab such as the Automatic Mirror Tracer (Model 5403), the Peabody Picture Vocabulary Test (3 rd Edition Form IIIA and Form IIIB) and the Wisconsin Card Sorting Task for Windows.

Proper citation: Howard Biobehavioral Core Laboratory (RRID:SCR_009862) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-0220-1cee-b2b9-4d8780000000

Core facility that provides the following services: Illumina Gene Expression, Affymetrix gene expression. The Partners HealthCare Center for Personalized Genetic Medicine Microarray Facility is a full service facility dedicated to providing analysis for DNA or RNA samples. We provide support for high density microarrays to the Harvard Partners research community, including Harvard medical School, hospitals in the Partners Healthcare network, investigators in the Dana-Farber/Harvard Cancer Center, and the Harvard School of Public Health. Our services are open to both the PHS and non-PHS community.

Proper citation: Harvard PCPGM Microarray Facility (RRID:SCR_009860) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-bca3-4116-02c0-2b6880000000

The West Quad Computing Group (WQCG) serves the research community of the BCMP and Cell Biology departments at Harvard Medical School. We provide support for your advanced computing needs, including design and maintenance of computational clusters, large data-set management, web and database backed applications, and workstation support, including workstations connected to research equipment. Please see Resources for more information, including a sample of some of our recent projects. We work in collaboration with the HMS Information Technology department. Please contact us using our support form for all of your computer support needs.

Proper citation: HMS West Quad Computing Group (RRID:SCR_009814) Copy   

•   Source: SciCrunch Registry

http://famu.eagle-i.net/i/00000137-3c2f-98f1-f0f1-ede280000000

Core facility that provides the following services: Animal handling training service, Animal surgery.

Proper citation: FAMU Animal care facility (RRID:SCR_009779) Copy   

•   Source: SciCrunch Registry

https://sites.dartmouth.edu/toxmetal/program-resources/trace-element-analysis/

Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions.

Proper citation: Dartmouth Trace Element Analysis Core Facility (RRID:SCR_009777) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012c-3d04-56dc-96ed-bdf580000000

TRAC is affiliated with the the Irradiation and Small Animal Imaging Shared Resource, which together provides irradiation services for basic and translational researchers and state-of-the-art non-invasive in vivo imaging of cultured cells and small animals. Services are used by Dartmouth investigators to irradiate cells in culture and small experimental animals. A separate set of irradiation devices is available through Norris Cotton Cancer Center for clinical and experimental irradiation of human patients.

Proper citation: Dartmouth Translational Research Animal Core (RRID:SCR_009778) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000013a-2c63-ce13-5088-2eef80000000

The SBGrid Core team provides research computing sysadmin support to structural biology laboratories in the Boston area.

Proper citation: HMS SBGrid Core (RRID:SCR_009811) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c7bd-3029-a061-4a6580000000

Core facility that provides the following services: Enzyme-linked immunosorbent spot assay service, Fluorescence microscopy service, Real-time PCR Service.

The NERCE Microbiology and Animal Resources Core maintains two laboratories, a BSL-2 and a BSL-3 laboratory, to support the research efforts of all New England investigators conducting research on NIAID priority pathogens. Each laboratory provides the physical environment, equipment, and support personnel required for scientists to work with these agents. The BSL-3 laboratory is an isolated suite that includes individual laboratory rooms and rooms for housing experimental animals, all within a single containment facility. The BSL-3 lab provides the extensive security and administrative support structure required for possession of CDC select agents. The laboratory acquires strains of viruses and bacteria, prepares seed stocks, and characterizes these seed stocks using phenotypic and molecular methods to ensure a well-characterized, pure biological reagent. Laboratory staff members assist investigators with experiments involving pathogen culture, fractionation of biological material, animal challenge, and vaccine and drug administration. The laboratory is equipped for commonly used analytical methods, including fluorescence microscopy, PCR, EIA, and ELISPOT. A single suite with both laboratory and experimental animal capability eliminates the need to transport infectious material between laboratories. The BSL-2 laboratory provides support required by the BLS-3 facility, access to attenuated strains exempt from select agent registration, and laboratory space for visiting investigators. Investigators interested in working with the Microbiology and Animal Resources core laboratory should complete the Core A Request Form and send it to Christine Anderson. See lab website for details. There are no charges for projects focused on NIAID priority pathogens and agents of emerging infectious disease.

Proper citation: HMS NERCE Microbiology and Animal Resources Core (RRID:SCR_009807) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c7a7-e0e5-a061-4a6580000000

Core facility that provides the following services: Protein production, Bacterial fermentation for recombinant protein production, Baculovirus culture, Protein purification.

The NERCE Biomolecule Production Core Laboratory is a core service laboratory with capability for expression and purification of recombinant proteins using bacterial and baculoviral expression systems, and preparation of bacterial carbohydrate components. It supports all New England investigators conducting research on NIAID priority pathogens that requires purified proteins or carbohydrates. Investigators are expected to provide data demonstrating efficacy of production and purification methods, as well as strains or purified recombinant plasmid preparations where applicable. See lab website for details. Please note that since the NERCE program will end in February 2014, our ability to support new requests for services is limited.

Proper citation: HMS NERCE Biomolecule Production Core Laboratory (RRID:SCR_009804) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c3-845c-db6e-7a3f80000000

Core facility that provides the following services: Soft-lithography service, Soft-lithography training and consultation.

The HMS Microfluidics Facility aims to make the tools of Microfabrication and Microfluidics available to all HMS users.

Proper citation: HMS Microfluidics Core Facility (RRID:SCR_009801) Copy   

•   Source: SciCrunch Registry

http://jsu.eagle-i.net/i/0000012b-00bc-22cd-3984-bcfb80000000

Core facility that provides the following services: Animal husbandry service. The Animal Care Facility (ACF) is one of the essential units of support and service to the biomedical research at Jackson State University. Its long term goal is to develop a state-of-the-art infrastructure as well as to provide technical and logistic support to RCMI investigators and other JSU faculty and students to conduct a high quality of animal research, in compliance with the guidelines and policies set for by accrediting and regulatory agencies, especially as they relate to IACUC protocol development, animal husbandry, food and water supply, veterinary care, quarantine and euthanasia, sanitation procedures, environmental monitoring, and record keeping. ACF provides accommodation for long-term storage of animals and maintains them in accordance with and in compliance with the PHS Policy on the Humane Care and Use of Laboratory Animals and the Animal Welfare Act, as described in the 2002 Guide for the Care and Use of Laboratory Animals.

Proper citation: JSU Animal Core Facility (RRID:SCR_009886) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a183-b053-55da-381e80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core provides the following services: Trypsinization service. Core provides a full range of services to the Joslin research community spanning from consulting on proteomic experimental design to data acquisition and analysis. The core operates a high throughput nano liquid chromatography, nanospray ionization, LTQ 2D ion trap tandem mass spectrometer system. This system is used for two routine proteomic services, including Targeted Protein Analysis and Protein Inventory. Targeted Protein Analysis is used to identify and provide in depth characterization, including phosphorylation site mapping, of proteins isolate by SDS-PAGE. Protein Inventory is used to catalogue the protein composition in a sample separated by 1D SDS-PAGE. This service provides information on protein identification, molecular weight (gel mobility), and spectral/peptide counts, a semi-quantitative measure of protein abundance. In addition, the Core works with investigators on specialized analyses involving tandem mass spectrometry, including specialized enzymatic digests (peptide preparation), selective reaction monitoring (SRM), and targeted peptide detection. The Proteomic Core provides in house database resources and analysis tools and also coordinates with Joslin's Bioinformatics Core to provide further assistance with data organization and interpretation. The Core hosts seminars on proteomic topics and provides instruction on practical and theoretical aspects of mass spectrometry-based proteomics.

Proper citation: Joslin Diabets Center Proteomics Core Facility (RRID:SCR_009883) Copy   

•   Source: SciCrunch Registry