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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Polyester
 
Resource Report
Resource Website
100+ mentions
Polyester (RRID:SCR_003602) software application, data processing software, data analysis software, software resource, simulation software An R package designed to simulate RNA sequencing experiments with differential transcript expression. Given a set of annotated transcripts, it will simulate the steps of an RNA-seq experiment (fragmentation, reverse-complementing, and sequencing) and produce files containing simulated RNA-seq reads. Simulated reads can be analyzed using a choice of downstream analysis tools. Polyester has a built-in wrapper function to simulate a case/control experiment with differential transcript expression and biological replicates. Users are able to set the levels of differential expression at transcripts of their choosing. This means they know which transcripts are differentially expressed in the simulated dataset, so accuracy of statistical methods for differential expression detection can be analyzed. Polyester offers several unique features: * Built-in functionality to simulate differential expression at the transcript level * Ability to explicitly set differential expression signal strength * Simulation of small datasets, since large RNA-seq datasets can require lots of time and computing resources to analyze * Generation of raw RNA-seq reads, as opposed to alignments or transcript-level abundance estimates * Transparency/open-source code standalone software, unix/linux, mac os x, windows, r, rna-seq is listed by: OMICtools OMICS_04272 SCR_003602 2026-02-16 09:46:09 487
EGAPP
 
Resource Report
Resource Website
1+ mentions
EGAPP (RRID:SCR_004189) EGAPP data or information resource, topical portal, portal Initiative to develop a systematic, evidence-based process for evaluating genetic tests and other applications of genomic technology that are rapidly moving from research to use in clinical practice. A key objective of this process is to provide objective, timely, and credible information that is clearly linked to the scientific evidence on specific applications of genetic and genomic tests. The primary focus of EGAPP activities is an independent, nonfederal expert panel, the EGAPP Working Group. Other components of the EGAPP initiative include a federal interagency, the CDC staff and consultants, and an EGAPP initiative evaluation team. genetic test, genomics, clinical, genomic technology, evaluation, public health is listed by: OMICtools
has parent organization: Centers for Disease Control and Prevention
OMICS_01538 SCR_004189 Evaluation of Genomic Applications in Practice and Prevention (EGAPP), Evaluation of Genomic Applications in Practice and Prevention 2026-02-16 09:46:17 1
SimSeq
 
Resource Report
Resource Website
10+ mentions
SimSeq (RRID:SCR_006947) SimSeq software application, software resource, simulation software An illumina paired-end and mate-pair short read simulator. This project attempts to model as many of the quirks that exist in Illumina data as possible. Some of these quirks include the potential for chimeric reads, and non-biotinylated fragment pull down in mate-pair libraries . bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Free biotools:simseq, OMICS_00258 https://bio.tools/simseq SCR_006947 2026-02-16 09:46:50 29
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) software application, software resource, simulation software Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-02-16 09:48:41 11
PubMed
 
Resource Report
Resource Website
10000+ mentions
PubMed (RRID:SCR_004846) data or information resource, database, bibliography Public bibliographic database that provides access to citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. PubMed citations and abstracts include fields of biomedicine and health, covering portions of life sciences, behavioral sciences, chemical sciences, and bioengineering. Provides access to additional relevant web sites and links to other NCBI molecular biology resources. Publishers of journals can submit their citations to NCBI and then provide access to full-text of articles at journal web sites using LinkOut. biomedical, literature, publication, open, access, bibliography, gold standard is used by: Knowledgebase for Addiction Related Genes
is used by: Drug Related Gene Database
is used by: ChannelPedia
is used by: Molecular Imaging and Contrast Agent Database
is used by: Colwiz
is used by: Nowomics
is used by: PINT
is listed by: OMICtools
is listed by: FORCE11
is listed by: LabWorm
is related to: Chilibot: Gene and Protein relationships from MEDLINE
is related to: ImpactStory
is related to: Automated recognition of brain region mentions in neuroscience literature.
is related to: Information Hyperlinked Over Proteins
is related to: PubMed Central
is related to: PIE the search
is related to: Anne O'Tate
is related to: PubBrain
is related to: Europe PubMed Central
is related to: ResearchGate
is related to: CBioC
is related to: CiteAb
is related to: LitInspector
is related to: RefMED
is related to: Pubmed Commons
is related to: iBIOFind
is related to: Ensembl Variation
is related to: MEDLINE
is related to: XplorMed
is related to: Linked Neuron Data
is related to: NCBI Structure
is related to: MeSH
is related to: MEDLINE
is related to: EBIMed
is related to: Coremine Medical
is related to: NIF Literature
is related to: GoPubMed
is related to: Integrated Auto-Extracted Annotation
is related to: Polbase
is related to: Integrated Manually Extracted Annotation
is related to: DaTo
is related to: NIF Registry Automated Crawl Data
has parent organization: NCBI
works with: Open Regulatory Annotation Database
works with: rentrez
NLM Free, Freely available nlx_82958, OMICS_01195 http://www.force11.org/node/4652
http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed
SCR_004846 Pub Med 2026-02-16 09:46:31 98390
Indelible
 
Resource Report
Resource Website
10+ mentions
Indelible (RRID:SCR_016163) software application, software resource, simulation software Software that generates nucleotide, amino acid and codon sequence data by simulating insertions and deletions (indels) as well as substitutions. It is used for biological sequence simulation of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time. indel, insertion, deletion, biological, sequence, simulation, multi-partitioned, nucleotide, amio-acid, codon, data, set, insertion, deletion, substitution, continous, time, non-homogeneous, non-stationary, phylogeny, simulator, evolution is listed by: Debian
is listed by: OMICtools
EPSRC/MRC Doctoral Training Centre studentship ;
BBSRC
PMID:19423664 Free, Available for download OMICS_15369 https://sources.debian.org/src/indelible/ SCR_016163 2026-02-16 09:48:58 23
Glide
 
Resource Report
Resource Website
10+ mentions
Glide (RRID:SCR_000187) Glide software application, software resource, simulation software Software package which approximates a complete search of the conformational, orientational, and positional space of the ligand in a given receptor. Used in drug development for predicting protein ligand binding modes and ranking ligands via high throughput virtual screening. ligand, receptor, docking, computation, virtual, screening, drug, discovery is listed by: OMICtools
is listed by: SoftCite
has parent organization: Schrodinger
works with: Ligprep
PMID:18428795 Restricted OMICS_01601 SCR_000187 2026-02-16 09:45:12 15
Psort
 
Resource Report
Resource Website
100+ mentions
Psort (RRID:SCR_007038) PSORT software application, data or information resource, topical portal, production service resource, data processing software, data analysis software, analysis service resource, service resource, software resource, data analysis service, portal, data set Portal to the PSORT family of computer programs for the prediction of protein localization sites in cells, as well as other datasets and resources relevant to localization prediction. The standalone versions are available for download for larger analyses. subcellular, localization, prediction, gram, gram-positive, gram-negative, sequence, fasta, protein, protein localization, cell, motif, profile, amino acid, subcellular localization is listed by: OMICtools
is related to: PSORT II
has parent organization: Simon Fraser University; British Columbia; Canada
OMICS_01634, nif-0000-31883 http://psort.hgc.jp/ SCR_007038 Psort.org, PSORT: Prediction of Protein Sorting Signals and Localization Sites in Amino Acid Sequences 2026-02-17 10:01:11 209
ProDom
 
Resource Report
Resource Website
100+ mentions
ProDom (RRID:SCR_006969) ProDom data or information resource, production service resource, analysis service resource, database, service resource, data analysis service Comprehensive set of protein domain families automatically generated from UniProt Knowledge Database. Automated clustering of homologous domains generated from global comparison of all available protein sequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. set, protein, domain, family, automatically, generated, UniProt, database, homologous, sequence, compare, FASEB list is listed by: OMICtools
is related to: UniProt
is related to: InterPro
has parent organization: PRABI
‘Programme de Bio-Informatique InterOrganismes ;
Re´seau des Ge´nopoles ;
European Union
PMID:15608179
PMID:12230033
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01698, nif-0000-03342 http://prodom.prabi.fr/prodom/current/html/home.php SCR_006969 2026-02-17 10:01:11 352
RTPrimerDB- The Real-Time PCR and Probe Database
 
Resource Report
Resource Website
10+ mentions
RTPrimerDB- The Real-Time PCR and Probe Database (RRID:SCR_007106) RTPrimerDB storage service resource, data or information resource, database, service resource, data repository Database for primer and probe sequences used in real-time PCR assays employing popular chemistries (SYBR Green I, Taqman, Hybridization Probes, Molecular Beacon) to prevent time-consuming primer design and experimental optimization, and to introduce a certain level of uniformity and standardization among different laboratories. Researchers are encouraged to submit their validated primer and probe sequence, so that other users can benefit from their expertise. The database can be queried using the official gene name or symbol, Entrez or Ensembl Gene identifier, SNP identifier, or oligonucleotide sequence. Different options make it possible to restrict a query to a particular application (Gene Expression Quantification/Detection, DNA Copy Number Quantification/Detection, SNP Detection, Mutation Analysis, Fusion Gene Quantification/Detection, Chromatin immunoprecipitation (ChIP)), organism (Human, Mouse, Rat, and others) or detection chemistry. primer, probe, sequence, real-time pcr, gene, assay, real-time pcr assay, FASEB list is listed by: OMICtools
has parent organization: Ghent University; Ghent; Belgium
PMID:18948285
PMID:16381959
PMID:12519963
Public, The community can contribute to this resource nif-0000-03431, OMICS_02322 SCR_007106 2026-02-17 10:01:03 48
CD-HIT
 
Resource Report
Resource Website
1000+ mentions
CD-HIT (RRID:SCR_007105) CD-HIT software application, source code, software resource, data processing software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software program for clustering biological sequences with many applications in various fields such as making non-redundant databases, finding duplicates, identifying protein families, filtering sequence errors and improving sequence assembly etc. It is very fast and can handle extremely large databases. CD-HIT helps to significantly reduce the computational and manual efforts in many sequence analysis tasks and aids in understanding the data structure and correct the bias within a dataset. The CD-HIT package has CD-HIT, CD-HIT-2D, CD-HIT-EST, CD-HIT-EST-2D, CD-HIT-454, CD-HIT-PARA, PSI-CD-HIT, CD-HIT-OTU and over a dozen scripts. * CD-HIT (CD-HIT-EST) clusters similar proteins (DNAs) into clusters that meet a user-defined similarity threshold. * CD-HIT-2D (CD-HIT-EST-2D) compares 2 datasets and identifies the sequences in db2 that are similar to db1 above a threshold. * CD-HIT-454 identifies natural and artificial duplicates from pyrosequencing reads. * CD-HIT-OTU cluster rRNA tags into OTUs The usage of other programs and scripts can be found in CD-HIT user''s guide. CD-HIT was originally developed by Dr. Weizhong Li at Dr. Adam Godzik''s Lab at the Burnham Institute (now Sanford-Burnham Medical Research Institute)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. cluster, protein, sequence, classification, domain, analysis, nucleotide sequence, dna, protein sequence, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: University of California at San Diego; California; USA
has parent organization: Google Code
is parent organization of: CD-HIT-OTU
NCRR 1R01RR025030 PMID:20053844
PMID:16731699
DOI:10.1093/bioinformatics/btl158
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_05157, biotools:cd-hit, nif-0000-30240 http://cd-hit.org
https://code.google.com/p/cdhit/
https://bio.tools/cd-hit
https://sources.debian.org/src/cd-hit/
http://bioinformatics.ljcrf.edu/cd-hi/
SCR_007105 CD-HIT Program 2026-02-17 10:01:12 3203
BioRAT
 
Resource Report
Resource Website
1+ mentions
BioRAT (RRID:SCR_007099) BioRAT text extraction software, software application, software resource, text-mining software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. An information extraction (IE) tool specifically designed to perform biomedical IE and which is able to locate and analyze both abstracts and full-length papers. BioRAT is a Biological Research Assistant for Text mining, and incorporates a document search ability with domain-specific IE. information extraction, search engine, biomedical, abstract, full-length paper is listed by: OMICtools
is related to: Comparative Toxicogenomics Database (CTD)
has parent organization: University College London; London; United Kingdom
PMID:15231534 THIS RESOURCE IS NO LONGER IN SERVICE SCR_013452, nif-0000-21061, OMICS_01175 SCR_007099 Biological Research Assistant for Text mining 2026-02-17 10:01:10 1
YM500
 
Resource Report
Resource Website
YM500 (RRID:SCR_007429) YM500 data or information resource, production service resource, analysis service resource, database, service resource, data analysis service An Integrative small RNA Sequencing database for miRNA research and provides an integrative web interface for miRNA quantification, isomiR identification, arm switching discovery, and, most of all, novel miRNA predictions. is listed by: OMICtools
has parent organization: National Yang-Ming University; Taipei; Taiwan
OMICS_00386 SCR_007429 YM500 miR-Seq Database 2026-02-17 10:01:15 0
VISTA Enhancer Browser
 
Resource Report
Resource Website
100+ mentions
VISTA Enhancer Browser (RRID:SCR_007973) VISTA Enhancer Browser storage service resource, data or information resource, database, service resource, data repository Resource for experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Most of these noncoding elements were selected for testing based on their extreme conservation in other vertebrates or epigenomic evidence (ChIP-Seq) of putative enhancer marks. Central public database of experimentally validated human and mouse noncoding fragments with gene enhancer activity as assessed in transgenic mice. Users can retrieve elements near single genes of interest, search for enhancers that target reporter gene expression to particular tissue, or download entire collections of enhancers with defined tissue specificity or conservation depth. human, noncoding fragment, mutant mouse strain, molecular neuroanatomy resource, image, telencephalon, development, genome, enhancer, dna fragment, embryo, embryonic mouse, brain, neural tube, eye, ear, heart, tail, limb, nose, cranial nerve, trigeminal, dorsal root ganglia, face, branchial arch, gene expression, annotation, vector, transgenic embryo, lacz reporter vector, lacz, biomaterial supply resource, in vivo, image collection, transcriptional enhancer, chip-seq, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: NIF Data Federation
is related to: One Mind Biospecimen Bank Listing
is related to: OMICtools
has parent organization: Lawrence Berkeley National Laboratory
American Heart Association ;
NIDCR ;
NHLBI HL066681;
NHGRI HG003988;
DOE contract DE-AC02-05CH11231;
NINDS NS062859;
DOE DE020060
PMID:17130149 Free, Freely available nif-0000-03637, OMICS_01568, biotools:vista_enhancer_browser https://bio.tools/vista_enhancer_browser SCR_007973 2026-02-17 10:01:09 233
QIIME
 
Resource Report
Resource Website
10000+ mentions
QIIME (RRID:SCR_008249) data analysis software, software application, data processing software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics. microbiome, microbial community, sequence data, data analysis software, bio.tools is used by: SortMeRNA
is used by: Nephele
is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
DOI:10.1038/nmeth.f.303 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01118, SCR_011948, OMICS_01521, biotools:qiime https://bio.tools/qiime SCR_008249 Quantitative Insights Into Microbial Ecology 2026-02-17 10:01:12 11036
ActiveDriver
 
Resource Report
Resource Website
10+ mentions
ActiveDriver (RRID:SCR_008104) ActiveDriver software application, data processing software, data analysis software, software resource, sequence analysis software A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:ActiveDriver, OMICS_00140 http://reimandlab.org/software/activedriver/
https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf
https://bio.tools/ActiveDriver
SCR_008104 2026-02-17 10:01:06 25
FigTree
 
Resource Report
Resource Website
10000+ mentions
FigTree (RRID:SCR_008515) data visualization software, data processing software, software application, software resource A graphical viewer of phylogenetic trees and a program for producing publication-ready figures. It is designed to display summarized and annotated trees produced by BEAST. data visualization software, graphical viewer, phylogenetic tree, annotate is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: University of Edinburgh; Scotland; United Kingdom
OMICS_04268, nif-0000-30567 https://sources.debian.org/src/figtree/ SCR_008515 FigTree 2026-02-17 10:01:22 11323
Augustus
 
Resource Report
Resource Website
1000+ mentions
Augustus (RRID:SCR_008417) software application, web application, data processing software, data analysis software, software resource, sequence analysis software Software for gene prediction in eukaryotic genomic sequences. Serves as a basis for further steps in the analysis of sequenced and assembled eukaryotic genomes. software, gene, prediction, eucaryotic, genomic, sequence is used by: BRAKER
is used by: BRO_annotation
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: Gsnap2Augustus
Deutsche Forschungsgemeinschaft (DFG) HO4545/1-1;;
STA1009/6-1 ;
Institute for Mathematics and Computer Science ;
Ernst Moritz Arndt University of Greifswald
PMID:23700307
DOI:10.1093/bioinformatics/btw494
Free, Available for download, Freely available SCR_015981, OMICS_07777, nif-0000-30133 https://sources.debian.org/src/autodock-vina/ SCR_008417 Augustus: Gene Prediction, WebAUGUSTUS, Augustus, Augustus [gene prediction] 2026-02-17 10:01:14 3542
Qvalue
 
Resource Report
Resource Website
10+ mentions
Qvalue (RRID:SCR_001073) data analysis software, software application, data processing software, software resource R package that takes a list of p-values resulting from the simultaneous testing of hypotheses and estimates their q-values. It is designed to measure the proportion of false positives when a test is significant. The software is capable of generating plots for visualization. It can be applied to problems in genomics, brain imaging, astrophysics, and data mining. p value, false positive, null hypothesis, genomics, brain imaging, astrophysics, data mining, r, visualization is listed by: OMICtools
is hosted by: Bioconductor
Free, Available for download, Freely available OMICS_00624 https://github.com/jdstorey/qvalue SCR_001073 2026-02-17 09:59:35 31
ToppCluster
 
Resource Report
Resource Website
100+ mentions
ToppCluster (RRID:SCR_001503) ToppCluster resource, production service resource, analysis service resource, service resource, data analysis service A tool for performing multi-cluster gene functional enrichment analyses on large scale data (microarray experiments with many time-points, cell-types, tissue-types, etc.). It facilitates co-analysis of multiple gene lists and yields as output a rich functional map showing the shared and list-specific functional features. The output can be visualized in tabular, heatmap or network formats using built-in options as well as third-party software. It uses the hypergeometric test to obtain functional enrichment achieved via the gene list enrichment analysis option available in ToppGene. term enrichment, gene, analysis, gene enrichment analysis, connectivity, heatmap, ortholog, microarray, function, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GenitoUrinary Development Molecular Anatomy Project
is related to: ToppGene Suite
NIDDK 1U01DK70219;
NIDDK P30DK078392;
NCRR U54 RR025216;
NIDCR U01DE020049
PMID:20484371 Free OMICS_02225, nlx_152801, biotools:toppcluster https://bio.tools/toppcluster SCR_001503 ToppCluster: A multiple gene list feature analyzer for the dissection of biological systems 2026-02-17 09:59:40 144

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