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http://casestudies.brain-map.org/celltax

Cellular Taxonomy of Mouse Visual Cortex by analyzing gene expression patterns at single cell level. Construction of cellular taxonomy of one cortical region, primary visual cortex, in adult mice done on basis of single cell RNA sequencing.

Proper citation: CellTax vignette (RRID:SCR_017000) Copy   

•   Source: SciCrunch Registry

https://biosciencecores.umd.edu/proteomics.html

Facility is equipped withThermoFisher Orbitrap Fusion Lumos Tribrid mass spectrometer that is interfaced to Dionex Ultimate3000 RSLCnano HPLC system. Facility also maintains 2 separate data stations dedicated for proteomics data processing, database searching, and generation of reports.

Proper citation: Maryland University Proteomics Core Facility (RRID:SCR_017739) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/flow-cytometry/index.html

Provides central location for flow cytometry instrumentation and education. Services include Flow Cytometry,Cell sorting, data analysis, training. Software packages to analyze data include ModFit LT, BD FACSDiva v6, Cell Quest Pro, and FlowJo vX, from facility workstations.

Proper citation: Nebraska University Medical Center Flow Cytometry Research Core Facility (RRID:SCR_017736) Copy   

•   Source: SciCrunch Registry

https://mbim.uams.edu/research-cores/flow-cytometry-core-facility/

Core provides flow cytometry instrumentation and analysis. Instruments include Fortessa, FacsAria and Image Stream.

Proper citation: Arkansas University College of Medicine Flow Cytometry Core Facility (RRID:SCR_017741) Copy   

•   Source: SciCrunch Registry

https://www.dbi.udel.edu/resources-and-facilities/protein-characterization

Facility consists of a Beckman Coulter ProteomeLab XL-I analytical ultracentrifuge is configured with a scanning UV/Vis detection system and Rayleigh Interference Optics. Used to characterize variety of biophysical properties of macromolecules such as molecular weight, sedimentation coefficient, diffusion coefficient, equilibrium constant and stoichiometry. Can assess sample heterogeneity (aggregation and purity), molecular conformation (folded or unfolded), composition (assembled or unassembled) and thermodynamic properties of interacting systems. Provides spectrum of data for protein characterization in solution.

Proper citation: Delaware Biotechnology Institute Protein Characterization Core Facility (RRID:SCR_017746) Copy   

•   Source: SciCrunch Registry

https://www.usd.edu/medicine/basic-biomedical-sciences/proteomics-core

Core provides proteomics services to researchers from South Dakota and the surrounding region to rapidly analyze and identify protein expression patterns in their experimental systems.Develops experimental design, protocols, data analysis and interpretation.Provides consulting and advice in grant proposal, as well as data preparation to be submitted to proteomics journal according to requirements.Offers training in use of common equipment such as scanner, spot cutter, imaging software, technique and protocol issues, and sample preparation.

Proper citation: South Dakota University SD BRIN Proteomics Core Facility (RRID:SCR_017743) Copy   

•   Source: SciCrunch Registry

https://www.cimr.cam.ac.uk/about/facilities/bioinformatics

Core provides biological data handling and analysis in differential expression analysis, next generation sequencing, networks, protein architecture, and motif searching for in house researchers.

Proper citation: Cambridge Institute for Medical Research Bioinformatics Core Facility (RRID:SCR_017186) Copy   

•   Source: SciCrunch Registry

http://www.tsl.ac.uk/groups/bioinformatics/

Core develops tools for high throughput sequence data to study non reference, non model organisms.

Proper citation: Sainsbury Laboratory Bioinformatics Core Facility (RRID:SCR_017185) Copy   

•   Source: SciCrunch Registry

http://hts.ku.edu/

Core offers high throughput screening of large chemical libraries of compounds to identify novel chemical entities that target biological system of interest.Provides target identification and validation, assay development, high throughput screening, hit confirmation, data mining and medicinal chemistry to facilitate hit to lead development.

Proper citation: Kansas University at Lawrence High Throughput Screening Laboratory Core Facility (RRID:SCR_017752) Copy   

•   Source: SciCrunch Registry

https://vgn.uvm.edu/bioinformatics/

Core provides expertise in biostatistics, microarray data analysis, proteome informatics, next generation sequencing data analysis, functional analysis, database development and information technology, including data storage infrastructure and high performance computing. Working closely with VGN Proteomics Facility, offers investigators experimental design consultations, comprehensive data analysis, data management and publishing, and manuscript and grant support. Core personnel also engage in teaching and training activities for data analysis and compute resources necessary for VGN network investigators. Our goal is to provide network researchers with bioinformatics expertise.

Proper citation: Vermont University Genetics Network Bioinformatics Core Facility (RRID:SCR_017686) Copy   

•   Source: SciCrunch Registry

http://www.giga.uliege.be/cms/c_151663/fr/giga-genomcis-lab-manager

Core provided by interdisciplinary center of biomedical research of Liege University. Develops and applies computational methods to extract information from large sets of biological and biomedical data.

Proper citation: University of Liege Interdisciplinary Cluster for Applied Genoproteomics Bioinformatics Core Facility (RRID:SCR_017163) Copy   

•   Source: SciCrunch Registry

https://umassmed.edu/saicf/

Core provides consultation services to assist researchers in designing imaging studies, limited labeling services and data acquisition and analysis.Core offers following services:Single Photon Computerized Tomography (SPECT),Positron Emission Computerized Tomography (PET), X-Ray Computerized Tomography (CT),NIR Optical Imaging of small animals.

Proper citation: Massachusetts University Medical School Radio Labeling Small Animal Translational Imaging Core Facility (RRID:SCR_017728) Copy   

•   Source: SciCrunch Registry

https://www.mcgill.ca/abif/

Core offers light microscopy platforms providing guidance to researchers with their projects from sample preparation to data analysis, expertise in cellular imaging including live cell imaging, FRAP, Fluorescence Lifetime Imaging Microscopy (FLIM), FRET, FCS, image correlation spectroscopy, TIRF, spectral imaging, lattice lightsheet, stimulated emission depletion (STED), high content screening, cellular image analysis, and custom image analysis, consultations, image processing, image analysis and preparation of data for publication.

Proper citation: McGill University Advanced BioImaging Facility (ABIF) (RRID:SCR_017697) Copy   

•   Source: SciCrunch Registry

https://uni-tuebingen.de/en/research/research-infrastructure/quantitative-biology-center-qbic/

Central unit for bioinformatics and omics technologies of University of Tübingen, Medical Faculty and Max Plank for Developmental Biology. Through partnering with on campus core facilities, offers services on full range of omics technologies. Data generation is complemented by integrated bioinformatics analyses, and all high throughput data is managed centrally.

Proper citation: University of Tübingen Quantitative Biology Center (RRID:SCR_017147) Copy   

•   Source: SciCrunch Registry

https://www.umassmed.edu/biocore/

Core to evaluate, select, and implement computational solutions for analysis of biological data.

Proper citation: Massachusetts University Medical School Bioinformatics Core Facility (RRID:SCR_017701) Copy   

•   Source: SciCrunch Registry

https://www.hpc.cam.ac.uk/compbio

Provides assistance in characterization and analysis of genomic variants, next generation sequencing data processing and analysis, computational systems biology, HPC and big data software development for genome scale data analysis, machine learning and data mining, cloud based solutions to process and manage large amounts of data, databases and genome scale data visualization.

Proper citation: University of Cambridge Bioinformatics and Computational Biology Services Core Facility (RRID:SCR_017154) Copy   

•   Source: SciCrunch Registry

https://cri.utsw.edu/facilities/moody-foundation-flow-cytometry/

Core provides flow cytometry services to scientists, offers analytical cytometry and high-speed sorting either in investigator operated format or facility staff assisted format, offers training for research personnel interested in learning how to design flow cytometry experiments, operate instrumentation and analyze data. Services include experimental design, protocol development, sample staining, instrument operation, data analysis, graphical production, sample processing as a Service (SpaaS). Facility is equipped with three cell sorters and four cell analyzers.

Proper citation: University of Texas Southwestern Medical Center Moody Foundation Flow Cytometry Core Facility (RRID:SCR_017807) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/xray/contacts.html

Core provides equipment and resources for crystallographic analysis of target macromolecules and small inorganic or organic molecules. Performes crystallization, X-ray diffraction data collection (both in-house and synchrotron sources) processing, phasing, crystallographic refinement, model building, and visualization. Structural data provide information including biological functions, 3D-folding, ligand binding (small molecule or protein), or mutational effect of target macromolecules. Services include Crystallization Screening; Data Collection Service: Diffraction experiments will be performed at in-house X-ray facility as well as synchrotron beam lines; Structure Determination and Analysis: complete data set collected at home or synchrotron will be processed for inorganic, organic, protein or nucleic acid structure determination, model building and crystallographic refinement. Other Structural Biology Related Services: core facility offers thorough analysis of macromolecular structure for publication or grant applications, also provides computational experiments such as homology modeling and in silico ligand docking.

Proper citation: Scripps Research Institute - Florida X ray Crystallography Core Facility (RRID:SCR_017835) Copy   

•   Source: SciCrunch Registry

http://www.ucdmc.ucdavis.edu/cancer/research/sharedresources/flowcytometry.html

Core provides access to expertise and instrumentation for analytical flow cytometry, cell sorting and laser scanning cytometry.Cell sorting and analytical cytometers are located at three sites in Davis and Sacramento for research use on recharge basis. Provides cell sorters for assisted sorting on appointment basis and provides training to investigators in acquiring data on analytic cytometers.Can advise on experiment design for flow cytometry, provides training to enable independent use of analytical cytometers, and familiarize investigators with popular data analysis software tools such as BD Diva and CellQuest, FlowJo, ModFit and iBrowser.

Proper citation: University of California Davis Flow Cytometry Shared Resource Laboratory Core Facility (RRID:SCR_017826) Copy   

•   Source: SciCrunch Registry

https://med.virginia.edu/flow-cytometry-facility/

Services include unassisted and assisted sample acquisition, cell sorting, mass cytometry (CyTOF), Luminex cytokine assays, antibody conjugation and data analysis.

Proper citation: University of Virginia School of Medicine Flow Cytometry Core Facility (RRID:SCR_017829) Copy   

•   Source: SciCrunch Registry