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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.waksman.rutgers.edu/genomics/home
Equipped with NextSeq500, MiSeq, and Ion Proton performs de novo genome sequencing, genome resequencing, ChIP-Seq and RNA-seq. Performs library construction, template preparation and sequencing of libraries or provides training in library preparation methods.Performs procedures to enrich or remove polyadenylated RNA, rRNA and/or tRNA as needed. Provides bioinformatics support for projects,data management and analysis plan before selecting samples and initiating data collection.
Proper citation: Rutgers University Waksman Institute of Microbiology Genomics Core Facility (RRID:SCR_011042) Copy
https://www.urmc.rochester.edu/research/rochester-genomics-center.aspx
Provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high throughput genomic sequencing, genotyping and gene expression in their research programs.Provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.
Proper citation: University of Rochester Genomics Research Center Core Facility (RRID:SCR_012359) Copy
https://www.urmc.rochester.edu/research/flow-core.aspx
Provides investigators with instrumentation along with expertise. Core instrumentation includes traditional analytical cytometers, full spectrum cytometer, cell sorters, imaging cytometers, small(nano) particle detection system, metabolomics instrument, and mass cytometer.
Proper citation: University of Rochester Medical Center Flow Cytometry Core Facility (RRID:SCR_012360) Copy
http://www.montana.edu/massspec/index.html
Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility.
Proper citation: Montana State University Mass Spectrometry Core Facility (RRID:SCR_012482) Copy
https://www.urmc.rochester.edu/research/electron-microscope.aspx
Electron Microscopy Resource supports ultra-structural interrogation of tissues, biologic solutions and nanomaterials for investigators utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM) and cryo-TEM.
Proper citation: University of Rochester Medical Center Electron Microscopy Core Facility (RRID:SCR_012366) Copy
https://www.ohio.edu/research/sharedequipment/ohio-university-genomics-facility
Facility offers Next-Generation Sequencing services, Sanger sequencing, Fragment Analysis, qPCR, data analysis. Provided services include DNA sequencing, fragment analysis, RNA, DNA, protein and cell cytometry through various equipment.
Proper citation: Ohio University Genomics Core Facility (RRID:SCR_012487) Copy
http://www.ohri.ca/stemcore/Default.aspx
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.
Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy
Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.
Proper citation: Arizona Genetics Core (RRID:SCR_012429) Copy
https://genetics.med.upenn.edu/cores/cell-center-services/
Facility provides basic cell culture training and services in various cell culture and related procedures e.g. Mycoplasma and Endotoxin testing. Services include cell culture at various scales, expansion of primary cells, seed cell cultures from on site cell bank, cell storage; large scale growth of hybridoma and other cell lines followed by antibody purification by protein G column or recombinant protein production; EBV induced transformation of lymphocytes.Offers hybridoma generation by cell fusion and screening and, transfection of mammalian cells. Facility prepares specialized cell culture media, Drosophila media and, various tissue culture and molecular biological reagents.
Proper citation: University of Pennsylvania Perelman School of Medicine Cell Center Services Core Facility (RRID:SCR_022391) Copy
https://www.itmat.upenn.edu/cnsc/
Provides expertise in medicinal chemistry, metal chelate chemistry, polymer synthesis, nanoparticle production and surface functionalization, and site-specific antibody labeling. Our chemists provide custom, problem specific support for researchers in medical, chemical, and materials science fields. Specific services include consultation and assistance with the design of chemical/medicinal compounds, in house synthesis of chemical/medicinal compounds, custom nanoparticle design and synthesis, custom nanoparticle surface functionalization, polymer and dendrimer synthesis, and site specific antibody labeling.
Proper citation: University of Pennsylvania Perelman School of Medicine Chemical and Nanoparticle Synthesis Core Facility (RRID:SCR_022390) Copy
https://wiki.umontreal.ca/spaces/plateformes/pages/189568061/Core+Facilities+-+CI2B
Offers instruments and services to support research in microscopy.
Proper citation: University of Montreal BioImaging Platform Core Facility (RRID:SCR_022311) Copy
Provides services in disciplines of genomics, microbiology and immunology. We engage in collaborative projects that benefit from close interactions with veterinarians and human clinicians alike.
Proper citation: University of Pennsylvania School of Veterinary Medicine Center for Host Microbial Interactions Core Facility (RRID:SCR_022310) Copy
https://www.med.upenn.edu/camris/
Center for Advanced Magnetic Resonance Imaging and Spectroscopy (CAMRIS) is a Radiology research core at the University of Pennsylvania’s Perelman School of Medicine providing oversight in the responsible use and application of Magnetic Resonance (MR) in research at Penn. CAMRIS oversees eight state-of-the-art whole-body MR scanners and provides scanning services by experienced technologists to a diverse community of investigators conducting innovative human and animal research.
Proper citation: University of Pennsylvania Center for Advanced Magnetic Resonance Imaging and Spectroscopy Core Facility (RRID:SCR_022398) Copy
https://www.med.upenn.edu/cbica/
Offers development and application of advanced computational and analytical techniques that quantify morphology and function from biomedical images, as well as on relating imaging phenotypes to genetic and molecular characterizations, and on integrating this information into diagnostic and predictive tools in era of personalized medicine. Computational methods can contribute significantly to automated, reproducible and quantitative interpretations of biomedical images. Translates advanced computational and analytical imaging methods to clinic, by providing forum in which interactions between researchers and clinicians facilitate bidirectional flow of ideas, algorithms and data between laboratory and clinic.
Proper citation: University of Pennsylvania Perelman School of Medicine Center for Biomedical Image Computing and Analytics Core Facility (RRID:SCR_022397) Copy
https://www.med.upenn.edu/CAMIPM/
Core dedicated to development and application of innovative, novel magnetic resonance and optical imaging techniques. Provides research and computing resources for projects with focus on developing instrumentation, methodologies, and data analysis techniques for quantitative assessment of functional, structural, and metabolic parameters in humans with use of multinuclear magnetic resonance, novel spectral, perfusion, functional, and optical imaging techniques.
Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Metabolic Imaging in Precision Medicine Core Facility (RRID:SCR_022396) Copy
Provides infrastructure support for research on human cognition, perception, affect, disordered cognition, and extension to preclinical models. By consolidating methodological expertise in these domain areas as services, center seeks to facilitate cutting edge research using largely shared set of methods and tools for elucidating brain behavior relationships in health and disease.
Proper citation: University of Pennsylvania Perelman School of Medicine Brain Science Service Center Core Facility (RRID:SCR_022394) Copy
https://www.med.upenn.edu/idom/drc/cores/rodent.html
Core (RMPC, formerly MPPMC) is metabolic core. Offers technology and phenotyping services to allow investigators to study metabolism in pre-clinical rodent models. Services include measurements of body composition (fat and lean mass) using NMR and DEXA, energy balance (food intake, locomotor activity, energy expenditure) using indirect calorimetry in either Columbus Instruments CLAMS system or Sable Systems Promethion System (with optional gas analyzer), and other in vivo metabolic phenotyping services (glucose clamps, insulin and glucose tolerance tests, telemetric monitoring of blood glucose or blood pressure, bomb calorimetry).
Proper citation: University of Pennsylvania Perelman School of Medicine Rodent Metabolic Phenotyping Core Facility (RRID:SCR_022427) Copy
https://www.med.upenn.edu/ipsccore/
Provides resources for disseminating human pluripotent stem cell technology within UPenn and surrounding research communities. �Our services include derivation of patient specific iPSCs, genome engineering of stem cell lines using CRISPR/Cas9 technology, and lineage specific differentiation of iPSCs/hESCs in 2D and 3D organoid culture.�Core has large collection of patient derived iPSC lines and cell lines of gastrointestinal tract (esophageal, pancreatic and intestinal) available to users.�Committed to training investigators in stem cell culture techniques and providing quality tested stem cell reagents to users.
Proper citation: University of Pennsylvania Perelman School of Medicine Induced Pluripotent Stem Cell Core Facility (RRID:SCR_022426) Copy
https://qb3.berkeley.edu/facility/ctaf-htsf/
Facility provides expert staff for training, services, and cell culturing space for HT automated cell seeding, liquid handling equipment, multi label plate reader and high content automated confocal imaging for any type of multi well, multi conditional mammalian cell experiments.
Proper citation: University of California at Berkeley QB3 High Throughput Screening CoreFacility (RRID:SCR_022304) Copy
https://www.med.upenn.edu/ris/
Shared resource machine shop serving various University of Pennsylvania Schools and Departments. Assists researchers to design and construct both laboratory and clinical instruments.
Proper citation: University of Pennsylvania Perelman School of Medicine Research Instrumentation Shop Core Facility (RRID:SCR_022424) Copy
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