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https://www.cceb.med.upenn.edu/bac

Provides wide range of biostatistical and epidemiological consulting services.

Proper citation: University of Pennsylvania Perelman School of Medicine Biostatistics Analysis Center Core Facility (RRID:SCR_022393) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/penn-acute-biobanking-core

Core encourages and facilitates microbiome focused research in pathogenesis, diagnosis and treatment of patients with critical illness. Core assists in research by providing de-identified samples with linked clinical metadata to support research in this area, collect specimens as needed in support of microbiome research, and offer support for development of such research in the critical care setting.

Proper citation: University of Pennsylvania Perelman School of Medicine Acute Care Biobanking Core Facility (RRID:SCR_022392) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/pet-center

Dedicated to continuing advancement of molecular imaging and seeks to build network of collaborators to conduct translational research using existing and new radiotracers to help better understand the diagnosis, physiology and treatment of multiple diseases. Educates referring clinicians and their patients about emerging benefits of PET/CT diagnostic procedures, other radiotracer imaging methods and radionuclide therapies as tools in their research and clinical practice.Provides opportunities and mentoring for individuals interested in pursuing work or collaborations within molecular imaging field. Provides scanners as well as cyclotron facility.

Proper citation: University of Pennsylvania Perelman School of Medicine Positron Emission Tomography Center Core Facility (RRID:SCR_022429) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/tbic.html

Mission is to act as portal for research community into Bio-medical imaging resources of University of Pennsylvania. Goals include creating and maintaining access for research community to Bio-medical imaging technologies, enabling research investigators to benefit from Bio-imaging expertise and experience, and educating researchers about Bio-medical imaging options through targeted seminars, research fellowships, and established training programs.

Proper citation: University of Pennsylvania Perelman School of Medicine Translational Bio-Imaging Center Core Facility (RRID:SCR_022428) Copy   

•   Source: SciCrunch Registry

https://vrc.med.upenn.edu/vrc-facilities/machine-shop/

Designes and buildes novel instruments and apparatus for research to user specifications. Works with users to develop initial project drawing, and will explore alternate designs to insure desired functionality. Fabricates user devices to high tolerance, using machine tools and materials, and can repair laboratory devices even if devices were constructed elsewhere.

Proper citation: University of Pennsylvania Perelman School of Medicine MINS Machine Shop Core Facility (RRID:SCR_022425) Copy   

•   Source: SciCrunch Registry

https://wiki.umontreal.ca/display/BiologieStructurale/Presentation+of+the+platform

Offers access to several scientific instruments intended to answer structural biological questions for scientific community.Consists of high field nuclear magnetic resonance spectrometers (500 MHz, 600 MHz with cryo-probe and 700 MHz) controlled with recent NEO consoles from Bruker, small angle X-rays scattering (SAXS) instrument, with high throughput robotics. SAXS can be coupled to liquid chromatography system for SEC-SAXS applications.Other instruments include size exclusion chromatography system coupled to multi angle light scattering detector (SEC-MALS), isothermal titration calorimetry (ITC) instrument as well as several liquid handling robots for rapid bio molecular crystal preparation and screening. Users have also access to bio-informatics room with several Linux computers for data analysis.Personnel is available and will teach and support users on instruments, research consultation and turn key services are also available upon request.

Proper citation: University of Montreal Structural Biology Platform Core Facility (RRID:SCR_022303) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/labs-and-centers/quantitative/physics-and-instrumentation-group

Core focuses on imaging in nuclear medicine, and engages in collaboration with clinicians and research investigators to optimize new instruments for applications in both clinical and pre clinical (animal) imaging scenarios. Offers equipment to build, test and characterize detectors for PET imaging, operates cluster of high powered Linux computers, which reconstruct, process, and analyze imaging data. Focuses on technology, which increases signal to noise of reconstructed images for whole body studies. Conducts research on SPECT imaging with emphasis on applications to small animal and brain imaging, oversees operation of cyclotron and imaging probe synthesis facilities.

Proper citation: University of Pennsylvania Perelman School of Medicine Nuclear Medicine Physics and Instrumentation Group Core Facility (RRID:SCR_022423) Copy   

•   Source: SciCrunch Registry

https://genetics.med.upenn.edu/cores/genomic-analysis-core/

Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. Core supports quantitative RNA profiling (gene expression) on Affymetrix GeneChips and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K real-time PCR machine. DNA profiling (genotyping) is offered on Affymetrix SNP GeneChip and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K. Agilent aCGH platform provides genome-wide chromosomal analysis.Users benefit from consultation and training available throughout their projects, including during experimental design and budget development, sample accrual, data management and analyses and, manuscript preparation.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis Molecular Profiling Core Facility (RRID:SCR_022389) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/pmi/facilities/muscle-physiology-assessment-core

Core provides investigators with customizable tools and methodolgies to assess in vivo exercise performance, metabolism and respiratory function, as well as in vivo and ex vivo muscle contractility. Provides guidance and training to investigators who want to learn how to collect and process muscle samples for specific uses.

Proper citation: University of Pennsylvania Perelman School of Medicine Muscle Physiology Assessment Core Facility (RRID:SCR_022422) Copy   

•   Source: SciCrunch Registry

http://www.confocal.uct.ac.za/

Light and fluorescence microscopy core facility with focus on applications in infectious disease, pathogen and human health research.

Proper citation: University of Cape Town Institute of Infectious Disease and Molecular Medicine Confocal and Light Microscope Imaging Core Facility (RRID:SCR_022309) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/live-cell-imaging-core/

Offers wide array of live cell imaging applications.Provides Nikon A1R Laser Scanning Confocal Microscopy system equipped with 4 laser lines to provide 6 different excitation/emission configurations; multiple photomultiplier tubes (PMTs), 32-channel spectral detector, full complement of microscope objectives, high speed image scanner, fully motorized stage and completely controllable environmental chamber. Users have access to NIS Elements AR software and 2D/3D deconvolution module offering sophisticated image analysis and processing features.

Proper citation: University of Pennsylvania Penn Dental Medicine Live Cell Imaging Core Facility (RRID:SCR_022442) Copy   

•   Source: SciCrunch Registry

https://lsbi.chem.tamu.edu/

Facility housed in Department of Chemistry.Designed to be multi user laboratory supporting major research initiatives. Instruments are currently available on fee for use basis, and others may be made available on case by case considerations.

Proper citation: Texas A and M University Laboratory for Synthetic Biologic Interactions Core Facility (RRID:SCR_022287) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/transgenic-mouse-core

Offers embryological manipulation services, focused on, but not limited to, murine model systems. These services primarily enable generation of genetically modified murine models, as well as experimental research in germ cell function and early embryonic development.

Proper citation: University of Pennsylvania Penn Vet Transgenic Mouse Core Facility (RRID:SCR_022441) Copy   

•   Source: SciCrunch Registry

https://histology.forsyth.org/

Core offers consulting and support services for both soft tissue and precise hard tissue analysis. Services include: tissue processing, embedding, sectioning, staining, and guidance on protocols. Can embed samples in standard molds or custom molds in paraffin, resin, or as frozen tissue for routine histology. Provides special stains and immunohistological studies.

Proper citation: Forsyth Institute Histology Core Facility (RRID:SCR_022165) Copy   

•   Source: SciCrunch Registry

https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/

Provides secure environment for investigators analyzing protected health information. �It coordinates acquisition, storage, and analysis of data from private and government sources (e.g., Medicare, Medicaid, and others) and facilitates their use by researchers who seek to answer important questions regarding health policy and health care.�

Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Health Services Research Data Center Core Facility (RRID:SCR_022439) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/comparative-pathology-core

Provides support to investigators utilizing animal models to study disease. Comparative Pathology Core, Abramson Cancer Center shared resource, provides expert pathological characterization and validation of mouse and other animal models used in biomedical research by offering expertise of board certified veterinary pathologists and access to histology, immunohistochemistry, and digital pathology services.

Proper citation: University of Pennsylvania Penn Vet Comparative Pathology Core Facility (RRID:SCR_022438) Copy   

•   Source: SciCrunch Registry

https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/

Provides LDI affiliated investigators access to high quality, skilled data analysts. HEDAP recruits, trains, and manages group of masters level and PhD level statistical analysts. These analysts work with multi disciplinary investigators across funded projects using statistical software packages such as SAS, Stata, and R to manipulate and analyze health care data under guidance of investigators and other collaborators.

Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Data Analyst Pool Core Facility (RRID:SCR_022437) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/imaging-core

Provides access to optical imaging capabilities for researchers at the University of Pennsylvania, Perelman School of Medicine, Children's Hospital of Philadelphia, and Wistar Institute. Provides instruments and expertise to perform widefield, confocal, multiphoton/intravital imaging, fluorescence lifetime imaging, high content live cell screening, long term single cell imaging, second harmonic imaging, structured illumination super resolution, and total internal reflection fluorescence microscopy, as well as software tools for image analysis. Core has adjacent (in and out) ULAR approved facility to house animals for long term live animal studies.

Proper citation: University of Pennsylvania Penn Vet Imaging Core Facility (RRID:SCR_022436) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/animal-model-core-corl

Supports discovery to invention to innovation in medical translation.Provides animal model development to enhance scientific rigor during in vivo studies in experimental or naturally occurring disease models. Studies can start on small scale leading towards pivotal non-clinical IND/IDE-enabling trials in support of FDA or OUS-FDA submissions. Core hosts PIs, trainees and sponsors during clinical procedures to support and enrich their experience in cross functional team setting.

Proper citation: University of Pennsylvania Animal Model Core Facility (RRID:SCR_022435) Copy   

•   Source: SciCrunch Registry

https://calm.mcmaster.ca/

Provides access to light microscopy, photo-patterning, and light-assisted 3D printing techniques to help researchers in science, engineering and life sciences as well as our industrial partners achieve their scientific goals.

Proper citation: McMaster University Centre for Advanced Light Microscopy Core Facility (RRID:SCR_022312) Copy   

•   Source: SciCrunch Registry