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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.broadinstitute.org/scientific-community/science/programs/cancer/ultrasome
An efficient methodology for detecting and delineating gains and losses of chromosomal material in DNA copy-number data.
Proper citation: Ultrasome (RRID:SCR_008465) Copy
http://www.sanger.ac.uk/cgi-bin/blast/submitblast/d_rerio
This Blast server offers searches against all D. rerio finished and unfinished clones in the Sanger sequencing pipeline. You can now also search the de novo assemblies generated from sequencing of one doubled haploid homozygous individual of each the AB and Tuebingen strain. Both fish were sequenced to ~40x coverage using Illumina GA sequencing technology and the sequences were assembled using Phusion2, resulting in a 1,33 Gb AB and a 1.48 Gb Tuebingen assembly. Due to the short reads and short inserts and no integration of physical or genetic map data, both assemblies are highly fragmented - with an N50 contig size of about 5kb. Mis-assembly errors may also be present in the contigs. Please note these assemblies are independent additions to the assemblies released by the zebrafish genome project and are intended to aid identification of polymorphisms between these two strains. Charity. Genome Research Limited is a charity registered in England with number 1021457
Proper citation: D. rerio Blast Server (RRID:SCR_008461) Copy
http://developer.yahoo.com/yui/
The YUI Library is a set of utilities and controls, written with JavaScript and CSS, for building richly interactive web applications using techniques such as DOM scripting, DHTML and AJAX. YUI is available under a BSD license and is free for all uses. YUI is proven, scalable, fast, and robust. Built by frontend engineers at Yahoo! and contributors from around the world, it''s an industrial-strength JavaScript library for professionals who love JavaScript.
Proper citation: Yahoo Developer Network (RRID:SCR_008594) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on Jan 16th 2025. WinLTP is a stimulation, data acquisition and on-line analysis electrophysiological software for studying Long-Term Potentiation (LTP), Long-term Depression (LTD), and related phenomena. WinLTP is multitasking and simultaneously runs 1) LTP stimulus/acquisition/analyzing sweeps with protocol scripting, and 2) continuous acquisition saving Axon Binary Files (abf). WinLTP runs on Windows PCI bus computers and uses National Instruments PCI M-Series boards and Axon Instruments'' Digidata 1320A and 1322A data acquisition boards. Other software that can use the M-Series boards includes Axograph Scientific''s AxoGraph X, WaveMetrics'' IGOR, National Instruments'' LabView, John Dempster''s Strathclyde Electrophysiology Suite (WinWCP and WinEDR), Silver lab''s Nclamp, and QUB data acquisition., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: WinLTP (RRID:SCR_008590) Copy
http://motif-x.med.harvard.edu
motif-x (short for motif extractor) is a software tool designed to extract overrepresented patterns from any sequence data set. The algorithm is an iterative strategy which builds successive motifs through comparison to a dynamic statistical background.
Proper citation: Motif Extractor (RRID:SCR_008628) Copy
A commercial organization that suppplies software which creates separate HIPAA-compliant repositories of de-identified patient records and reports. This software allows clinicians, researchers, and administrative leadership to safely access, search, share, and analyze de-identified patient-level data. DE-ID can be acquired as stand-alone tool or integrated with data networks or clinical information systems.
Proper citation: DE-ID Data Corp (RRID:SCR_008668) Copy
http://www.oracle.com/us/sun/index.htm
Oracle''s complete, open, and integrated product strategy provides flexibility and choice to our customers across their IT infrastructure. Now, with Sun server, storage, operating-system, and virtualization technology, Oracle is the only vendor able to offer a complete technology stack in which every layer is integrated to work together as a single system. Oracle''s open architecture and multiple operating-system options gives our customers unmatched benefits, including excellent system availability, scalability, energy efficiency, powerful performance, and low total cost of ownership Starting more than 30 years ago with Oracle''s innovative relational database, the Oracle stack today includes Oracle Enterprise Linux, Oracle VM, Oracle Fusion Middleware, and the largest and most complete set of industry and business applications software on the market. The addition of Sun storage and systems technology makes the Oracle stack complete. Oracle integrates every layer of the IT stack to deliver compelling value, based on high system availability and security, stunning performance, and low TCO. Only Oracle can offer this stack advantage to its customers through deep and seamless integration between the tiers that our competitors cannot match.
Proper citation: SUN Interface Engine (RRID:SCR_008659) Copy
http://pga.mgh.harvard.edu/oligopicker/
Software to help selecting up to five oligo probes for each of the DNA sequences you provided for microarray spotting.
Proper citation: OligoPicker (RRID:SCR_008720) Copy
http://www.opentox.org/dev/apis/api-1.1/structure
Tools for the integration of data from various sources (public and confidential), for the generation and validation of computer models for toxic effects, libraries for the development and seamless integration of new algorithms, and scientifically sound validation routines. The goal of OpenTox is to develop an interoperable predictive toxicology framework which may be used as an enabling platform for the creation of predictive toxicology applications. OpenTox is relevent for users from a variety of research areas: Toxicological and chemical experts (e.g. risk assessors, drug designers, researchers) computer model developers and algorithm developers non specialists requiring access to Predictive Toxicology models and data OpenTox applications can combine multiple web services providing users access to distributed toxicological resources including data, computer models, validation and reporting. Applications are based on use cases that satisfy user needs in predictive toxicology. OpenTox was initiated as a collaborative project involving a combination of different enterprise, university and government research groups to design and build the initial OpenTox framework. Additionally numerous organizations with industry, regulatory or expert interests are active in providing guidance and direction. The goal is to expand OpenTox as a community project enabling additional expert and user participants to be involved in developments in as timely a manner as possible. To this end, our mission is to carry out developments in an open and transparent manner from the early days of the project, and to open up discussions and development to the global community at large, who may either participate in developments or provide user perspectives. Cooperation on data standards, data integration, ontologies, integration of algorithm predictions from different methods, and testing and validation all have significant collaboration opportunities and benefits for the community. OpenTox is working to meet the requirements of the REACH legislation using alternative testing methods to contribute to the reduction of animal experiments for toxicity testing. Relevant international authorities (e.g., ECB, ECVAM, US EPA, US FDA) and industry organizations participate actively in the advisory board of the OpenTox project and provide input for the continuing development of requirement definitions and standards for data, knowledge and model exchange. OpenTox actively supports the development and validation of in silico models and algorithms by improving the interoperability between individual systems (common standards for data and model exchange), increasing the reproducibility of in silico models (by providing a quality source of structures, toxicity data and algorithms) and by providing scientifically sound and easy-to-use validation routines. OpenTox is committed to the support and integration of alternative testing methods using in vitro assay approaches, systems biology, stem cell technology, and the mining and analysis of human epidemiological data. Hence the framework design must take into account extensibility to satisfy a broad range of scientific developments and use cases.
Proper citation: OpenTox Framework (RRID:SCR_008686) Copy
http://www.procure.ca/index.php
The main goal of PROCURE is to provide science and humanity with means to help prevent and cure prostate cancer a disease which this year alone will be diagnosed in an estimated 25,500 Canadian men and one which will, on average, take the lives of 85 men every week. PROCURE strives to redefine the boundaries of research and knowledge by: * Initiating an on-going dialogue with the public and healthcare community to provide needed information and support through accessible means such as: ** A comprehensive website in French and English ** Lectures and special events ** Free book on prostate cancer * Funding and structuring over time a bank of biological materials and data on men with prostate cancer as well as those at risk of developing the disease. Such a Biobank, as it is known, will accelerate breakthrough scientific discovery. Join our alliance today by informing yourself and loved ones. Encourage the other men you care about to have an examination. Make a contribution to our cause. Help us keep information on this site up-to-date. In doing so you will become part of the force against prostate cancer!
Proper citation: PROCURE (RRID:SCR_008722) Copy
http://dc.crs4.it/projects/biodoop
A suite of parallel bioinformatics applications based upon a popular open-source Java implementation of MapReduce, Hadoop.
Proper citation: Biodoop (RRID:SCR_008711) Copy
http://www.scioncorp.com/pages/product_prices.htm#Software
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. Commercial software vendor.
Proper citation: Scion Image (RRID:SCR_008673) Copy
http://code.google.com/p/drgap/
Designed to identify Driver Genes and Pathways in cancer genome sequencing studies.
Proper citation: DrGaP (RRID:SCR_008670) Copy
http://www.danga.com/memcached/
A commercial distributed memory object caching system, generic in nature, but originally intended for use in speeding up dynamic web applications by alleviating database load. memcached allows you to take memory from parts of your system where you have more than you need and make it accessible to areas where you have less than you need. With memcached, you can see that all of the servers are looking into the same virtual pool of memory. This means that a given item is always stored and always retrieved from the same location in your entire web cluster.
Proper citation: Memached (RRID:SCR_008625) Copy
Provides support for the Apache community of open-source software projects. The Apache projects are characterized by a collaborative, consensus based development process, open and pragmatic software license, and a desire to create high quality software that leads the way in its field.
Proper citation: Apache Software Foundation (RRID:SCR_008588) Copy
Gnuplot is a portable command-line driven graphing utility for linux, OS/2, MS Windows, OSX, VMS, and many other platforms. The source code is copyrighted but freely distributed (i.e., you don''t have to pay for it). It was originally created to allow scientists and students to visualize mathematical functions and data interactively, but has grown to support many non-interactive uses such as web scripting. It is also used as a plotting engine by third-party applications like Octave. Gnuplot has been supported and under active development since 1986. Gnuplot supports many types of plots in either 2D and 3D. It can draw using lines, points, boxes, contours, vector fields, surfaces, and various associated text. It also supports various specialized plot types. Demos here. Gnuplot supports many different types of output: interactive screen terminals (with mouse and hotkey input), direct output to pen plotters or modern printers, and output to many file formats (eps, fig, jpeg, LaTeX, metafont, pbm, pdf, png, postscript, svg, ...). Gnuplot is easily extensible to include new output modes. Recent additions include an interactive terminal based on wxWidgets and the creation of mousable graphs for web display using the HTML5 canvas element.
Proper citation: Gnuplot (RRID:SCR_008619) Copy
http://www.broadinstitute.org/cancer/cga/invex/
A permutation-based method (written in Python) for ascertaining genes with a somatic mutation distribution showing evidence of positive selection for non-silent mutations.
Proper citation: InVEx (RRID:SCR_008734) Copy
A listing of grants and other funding types to support health research, programs and scholarship. Funding sources most frequently listed on ScanGrants include those of private foundations, corporations, businesses, and not-for profit organizations. Finding and listing less traditional funding opportunities is also a priority. Federal and state funding sources are typically not included on ScanGrants because they are readily available on other sites (e.g., www.grants.gov). The funding sources listed on ScanGrants may be of interest to virtually anyone associated with the health field medical researchers, social workers, nurses, students, community-based health educators, academics and others. They include grants, scholarships, fellowships, prizes for scientific achievement or distinguished service, travel awards to professional meetings, abstract, essay and poster awards among other sources of funding. ScanGrants is a free resource that lists funding opportunities for researchers and students at many stages of their research projects or careers. Examples include: poster awards for completed projects; travel grants that could help finance trips to meetings that would enable you to discuss with peers in your field projects you are contemplating undertaking or in the midst of; calls for nominations for science prizes you could nominate colleagues you admire for; and announcements of funding for programs for violence or disease prevention. We invite you to give ScanGrants a try. If you would like your grant or scholarship announcement reviewed for possible posting on ScanGrants, please fill out the form with your name, email address, link to the original online listing of the funding opportunity, the title of the grant or scholarship and as much additional detail as possible.
Proper citation: ScanGrants (RRID:SCR_008736) Copy
H. Lee Moffitt Cancer Center & Research Institute has made a lasting commitment to the prevention and cure of cancer, working tirelessly in the areas of patient care, research and education to advance one step further in fighting this disease. As part of an elite group of National Cancer Institute (NCI) Comprehensive Cancer Centers, Moffitt focuses on the development of early stage translational research aimed at the rapid translation of scientific discoveries to benefit patient care. Since the first patient admission in October 1986, Moffitt physicians, scientists and staff members have worked together to establish a tradition of excellence offered in an atmosphere characterized by kindness, caring and hope. The Cancer Center''s future growth in clinical care and research rests firmly on this tradition and makes possible the changes ahead. The mission of Moffitt Cancer Center is to contribute to the prevention and cure of cancer. Moffitt''s vision is to be the leader in scientific discovery and translation into compassionate care, cures, and prevention of cancer for our community and the world. As it grows to fulfill its mission, the Cancer Center will continue to be distinguished by its compassionate and effective patient care. Moffitt Cancer Center is a not-for-profit institution. It includes private patient rooms, the Southeast''s largest Blood and Marrow Transplant Program, outpatient treatment programs that record more than 320,500 visits a year, the Moffitt Research Center, Moffitt Cancer Center at International Plaza and the Lifetime Cancer Screening & Prevention Center.
Proper citation: Moffitt Cancer Center (RRID:SCR_008730) Copy
http://helix.wustl.edu/dcaps/dcaps.html
A simple program for finding nearly matched primers Sponsor: This material is based upon work supported by the National Science Foundation under Grant No. 0114726.
Proper citation: dCAPS Finder (RRID:SCR_008612) Copy
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