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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Necklace
 
Resource Report
Resource Website
1+ mentions
Necklace (RRID:SCR_016103) software application, data processing software, software resource, alignment software, image analysis software Software that combines reference and assembled transcriptomes for RNA-Seq analysis. It replaces many manual steps in the pipeline of RNA-Seq analyses involving species with incomplete genome or annotations. RNA, Transcriptome, Non-model species, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:28836999 Free, Available for download biotools:necklace https://bio.tools/necklace SCR_016103 Lace software 2026-02-15 09:21:31 3
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) software application, sequence analysis software, data processing software, software resource, data analysis software Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-02-15 09:21:13 1
DOGMA
 
Resource Report
Resource Website
100+ mentions
DOGMA (RRID:SCR_015060) web application, software resource Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. chloroplast, mitochondria, genome annotation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:15180927 Freely available biotools:DOGMA https://bio.tools/DOGMA SCR_015060 Dual Organellar GenoMe Annotator, Dual Organellar GenoMe Annotator (DOGMA) 2026-02-15 09:20:48 413
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE data or information resource, narrative resource, wiki Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-02-15 09:21:14 16
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) software application, data visualization software, sequence analysis software, data processing software, software resource, data analysis software Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview
https://sources.debian.org/src/seaview/
SCR_015059 2026-02-15 09:21:16 1777
LTR_Finder
 
Resource Report
Resource Website
500+ mentions
LTR_Finder (RRID:SCR_015247) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Web software capable of scanning large-scale sequences for full-length LTR retrotranspsons., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Long Terminal Repeat retrotransposons, Long Terminal Repeat, retrotransposon prediction, genome sequences, LTR prediction, LTR structure prediction, DNA sequence, biotools is listed by: Debian
is listed by: bio.tools
Fudan University ;
Shanghai ;
China
PMID:17485477 THIS RESOURCE IS NO LONGER IN SERVICE SCR_020944, biotools:ltr_finder https://bio.tools/ltr_finder SCR_015247 LTR Finder 2026-02-15 09:21:10 795
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) software application, sequence analysis software, data processing software, software resource, data analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX
https://bio.tools/MeroX
https://bio.tools/MeroX
SCR_014956 2026-02-15 09:21:06 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) software application, data processing software, algorithm resource, software resource, data analysis software Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Swiss National Science Foundation ;
Marie Curie International Outgoing Fellowship
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco
https://bio.tools/busco
https://sources.debian.org/src/busco/
SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-02-15 09:21:06 7284
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) software application, sequence analysis software, source code, data processing software, software resource, data analysis software Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2
https://bio.tools/hisat2
https://sources.debian.org/src/hisat2/
SCR_015530 HISAT 2026-02-15 09:21:18 17595
WEIGHTED FDR
 
Resource Report
Resource Website
WEIGHTED FDR (RRID:SCR_013442) software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, r, ms-windows, linux, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154604, SCR_000848, nlx_154690, biotools:weighted_fdr https://bio.tools/weighted_fdr SCR_013442 R/WEIGHTED_FDR 2026-02-15 09:20:44 0
SASQUANT
 
Resource Report
Resource Website
1+ mentions
SASQUANT (RRID:SCR_013122) software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. SAS software program to estimate genetic effects and heritabilities of quantitative traits in breeding populations consisting of six related generations (entry from Genetic Analysis Software) gene, genetic, genomic, sas, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154610, biotools:sasquant https://bio.tools/sasquant SCR_013122 2026-02-15 09:20:40 4
QMSIM
 
Resource Report
Resource Website
50+ mentions
QMSIM (RRID:SCR_013123) software application, software resource Software application designed to simulate a wide range of genetic architectures and population structures in livestock. Large scale genotyping data and complex pedigrees can be efficiently simulated. QMSim is a family based simulator, which can also take into account predefined evolutionary features, such as LD, mutation, bottlenecks and expansions. The simulation is basically carried out in two steps: In the first step, a historical population is simulated to establish mutation-drift equilibrium and, in the second step, recent population structures are generated, which can be complex. QMSim allows for a wide range of parameters to be incorporated in the simulation models in order to produce appropriate simulated data. (entry from Genetic Analysis Software) gene, genetic, genomic, c++, ms-windows, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154560, biotools:qmsim https://bio.tools/qmsim SCR_013123 Qtl and Marker SIMulator 2026-02-15 09:20:38 57
imDEV
 
Resource Report
Resource Website
1+ mentions
imDEV (RRID:SCR_014674) systems interoperability software, software application, software resource A software application of RExcel that integrates R into Excel as an embedded additon for omics tasks and analysis. It can be used specifically for tasks concerning multivariate data visualization, exploration, and analysis. imDev has interactive modules for dimensional reduction, prediction, feature selection, analysis of correlation, and generation of networked structures, all of which provide an integrated environment for systems level analysis of multivariate data. statistical analysis, statistical analysis package, r, r package, excel, data visualization, feature selection, omics, systems interoperability, software, metabolomics, bio.tools is listed by: Metabolomics Workbench
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/bioinformatics/bts439 Supports Microsoft Excel versions 2003-2010 biotools:imdev https://sourceforge.net/projects/imdev/
https://bio.tools/imdev
SCR_014674 Interactive modules for Data Exploration and Visualization, Interactive modules for Data Exploration and Visualization (imDEV) 2026-02-15 09:20:58 8
Protein Prospector
 
Resource Report
Resource Website
500+ mentions
Protein Prospector (RRID:SCR_014558) software toolkit, software resource A package of over twenty mass spectrometry-based tools primarily geared toward proteomic data analysis and database mining. It can be run from the command line, but is primarily used through a web browser, and there is a public website that allows anyone to use the software without local installation. Tandem mass spectrometry analysis tools are used for database searching and identification of peptides, including post-translationally modified peptides and cross-linked peptides. Support for isotope and label-free quantification from this type of data is provided. MS-Viewer software allows sharing and displaying of annotated spectra from many different tandem mass spectrometry data analysis packages. Other tools include software for analyzing peptide mass fingerprinting data (MS-Fit); prediction of theoretical fragmentation of peptides (MS-Product); theoretical chemical or enzymatic digestion of proteins (MS-Digest); and theoretical modeling of the isotope distribution of any chemical, including peptides (MS-Isotope). Searches using amino acid sequence can be used to identify homologous peptides in a database (MS-Pattern); the use of the combination of amino acid sequence and masses can be used for homologous peptide and protein identification using MS-Homology. Tandem mass spectrometry peak list files can be filtered for the presence of certain peaks or neutral losses using MS-Filter. Given a list of proteins, MS-Bridge can report all potential cross-linked peptide combinations of a specified mass. Given a precursor peptide mass and information about known amino acid presence, absence, or modifications, MS-Comp can report all amino acid combinations that could lead to the observed mass. database search program, database search, database management, peptide, protein, mass spectrometry, ms, utility program, batch msms, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at San Francisco; California; USA
Open source, Freely available to academic researchers biotools:proteinprospector https://bio.tools/proteinprospector SCR_014558 ProteinProspector 2026-02-15 09:20:56 569
Bionitio
 
Resource Report
Resource Website
1+ mentions
Bionitio (RRID:SCR_017259) software toolkit, software resource Open source software tool to provide template for command line bioinformatics tools in various programming languages. Program reads one or more input FASTA files, computes variety of statistics on each file, and prints tabulated output. Used as basis for learning and as foundation for starting new projects. template, command, line, bioinformatic, tool, programming, language, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: University of Melbourne; Victoria; Australia
Free, Available for download, Freely available biotools:bionitio https://bio.tools/Bionitio SCR_017259 2026-02-15 09:21:17 1
iPiG
 
Resource Report
Resource Website
iPiG (RRID:SCR_016164) iPiG software application, standalone software, software resource Standalone software tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. integration, peptide, spectrum, match, genome, browser, visualization, experiment, pms, ms, bio.tools uses: UCSC Genome Browser
is listed by: bio.tools
is listed by: Debian
Robert Koch-Institute PMID:23226516
DOI:10.1371/journal.pone.0050246
Free, Available for download biotools:ipig, OMICS_06913 https://bio.tools/ipig
https://sources.debian.org/src/ipig/
SCR_016164 iPiG: Integrating Peptide Spectrum Matches Into Genome Browser Visualizations 2026-02-15 09:21:02 0
Chromosome Scale Assembler
 
Resource Report
Resource Website
1+ mentions
Chromosome Scale Assembler (RRID:SCR_017960) CSA software application, software resource Software pipeline for high-throughput chromosome level vertebrate genome assembly. Pipeline, which after contig assembly performs post assembly improvements by ordering assembly and closing gaps, as well as splitting of low supported regions. Assembly, chromosome, vertebrate, genome, contig, closing, gap, splitting, low, supported, region, bio.tools is listed by: bio.tools
is listed by: Debian
German Research foundation Free, Available for download, Freely available biotools:csa2.6 https://bio.tools/CSA2.6 SCR_017960 Chromosome Scale Assembler 2026-02-15 09:22:09 5
Bio2BEL
 
Resource Report
Resource Website
1+ mentions
Bio2BEL (RRID:SCR_017659) software toolkit, software resource Software Python package enabling Biological Expression Language to act as semantic integration layer for multi modal and multi scale data sets in life sciences. Used for integrating biological databases and structured data sources in BEL. Has ability to support curation of pathway mappings, integration of pathway databases, and machine learning applications. Biological, expression, language, integration, layer, dataset, biological, database uses: PyBEL
is listed by: Debian
is listed by: bio.tools
is related to: Biological Expression Language
DOI:10.1101/631812 Free, Available for download, Freely available biotools:bio2bEL, BioTools:Bio2BEL https://github.com/bio2bel/bio2bel
https://bio.tools/Bio2BEL
https://bio.tools/Bio2BEL
SCR_017659 2026-02-15 09:22:06 7
BioBERT
 
Resource Report
Resource Website
10+ mentions
BioBERT (RRID:SCR_017547) software application, software resource Pre-trained biomedical language representation model for biomedical text mining. This repository provides fine-tuning codes of BioBERT, language representation model for biomedical domain, especially designed for biomedical text mining tasks such as biomedical named entity recognition, relation extraction, question answering, etc. Pretrained, biomedical, language, representation, model, text, mining, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: BERT
National Research Foundation of Korea DOI:10.1093/bioinformatics/btz682 Free, Available for download, Freely available biotools:biobERt https://github.com/naver/biobert-pretrained
https://bio.tools/BioBERT
SCR_017547 Bidirectional Encoder Representations from Transformers for Biomedical Text Mining 2026-02-15 09:22:08 45
EpiDISH R package
 
Resource Report
Resource Website
1+ mentions
EpiDISH R package (RRID:SCR_018004) EpiDISH software toolkit, software resource Software R package provides tools to infer proportions of priori known cell-types present in sample representing mixture of such cell-types. Comparison of reference based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies. Epigenetic, sample heterogeneity, reference, algorithm, correcting, cell type, bio.tools is listed by: bio.tools
is listed by: Debian
Royal Society Newton Advanced Fellowship ;
Chinese Academy of Sciences ;
Shanghai Institute for Biological Sciences ;
Max-Planck Society ;
NSFC 31571359;
EU-FP7
PMID:28193155 Free, Available for download, Freely available biotools:epidish https://github.com/sjczheng/EpiDISH
https://bio.tools/epidish
SCR_018004 Epigenetic Dissection of Intra-Sample Heterogeneity 2026-02-15 09:22:18 8

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