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https://nmrcore.uhnresearch.ca/

NMR Core Facility is equipped with NMR spectrometers allowing researchers to Characterize bio-molecular structures at the atomic resolution with exquisite details;Identify protein interactions with binding partners in order to understand their architecture;Study protein dynamic;Study protein post-translational modifications acting as molecular switches;Study structure-function relationships of biological proteins to gain insight into biological processes in relation to human disease;Screening of High-throughput drug-like leads for novel therapeutic targets;Study Metabolites of interest.Core facility houses high-field NMR spectrometers equipped with cryogenically cooled probes (1H or 13C optimized) for enhanced sensitivity.

Proper citation: University Health Network Nuclear Magnetic Resonance Core Facility (RRID:SCR_027548) Copy   

•   Source: SciCrunch Registry

https://sc.edu/rc

Reporting to the Division of Information Technology, and working in close partnership with the Office of Research, works with researchers to improve their project performance and secure computing resources not only at the university level but beyond, to National Labs and other high profile HPC resources.

Proper citation: University of South Carolina Research Computing Core Facility (RRID:SCR_027488) Copy   

•   Source: SciCrunch Registry

https://mccaingubiobank.ca/

Core supports biomarker discovery and enhancing future cancer research in the areas of genomics, proteomics and epidemiology. Provides serialized collections of biospeciments throughout patient prognosis. Clinical time point collections are based on input from our expert surgical, medical, and radiation oncologist teams.

Proper citation: University Health Network McCain GU Biobank (RRID:SCR_027521) Copy   

•   Source: SciCrunch Registry

https://jdmiresearch.ca/

Core services include Imaging Modalities:MRI,PET-MRI,CT,PET-CT,Ultrasound / X-Ray,Interventional / Biopsies;Consultation:Pre-grant submission consultations,Pre-trial launch consultations / site initiation visists,Feasibility assessments MRI physics consultation; Protocol Development / Site Feasibility:Industry site feasibility questionnaires, Protocol development of medical imaging studies and clinical trials; Post-Processing of Images:Tumour measurements, Volumetric measurements.

Proper citation: University Health Network Joint Department of Medical Imaging Research Office JDMI RO Core Facility (RRID:SCR_027520) Copy   

•   Source: SciCrunch Registry

https://pmlivingbiobank.uhnresearch.ca/

Core provides services for the use of Xenograft (PDX) models listed in open global catalogue of PDX models for comprehensive search and attribute filtering support for clinico-pathological and molecular data. Molecular data and visualization of profiled models could be accessed through the institute's portal.

Proper citation: University Health Network Princess Margaret Living PDX Core Facility (RRID:SCR_027523) Copy   

•   Source: SciCrunch Registry

https://www.pmgenomics.ca/pmgenomics/

Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.

Proper citation: University Health Network Princess Margaret Genomics Centre PMGC Core Facility (RRID:SCR_027524) Copy   

•   Source: SciCrunch Registry

https://www.clf.stfc.ac.uk/Pages/Octopus-new.aspx

National imaging facility that offers access to single molecule imaging, confocal microscopy, superresolution imaging, light sheet microscopy, optical trapping and cryoscanning electron microscopy. Offers expert guidance and advice for light and electron microscopy experiments alongside advanced instruments for fluorescence and electron microscopy.

Proper citation: Science and Technology Facilities Council Central Laser Facility OCTOPUS Microscopy Core Facility (RRID:SCR_027515) Copy   

•   Source: SciCrunch Registry

https://uhnbiospecimenservices.com/

Core provide services for the enhancement and progression of novel and innovative research and discovery. Provides human biospecimen samples such as: fresh frozen and formalin fixed paraffin embedded (FFPE) tissue, compartmentalized blood components such as serum, plasma, and whole blood peripheral blood mononuclear cells (PBMCs) and other biofluids, including saliva and urine; Tissue microarray (TMA) construction and quantitative image analysis of TMA sections, Laser capture microdissection (LCM), digital slide scanning, quantitative image, and pathological/clinical analysis for various tumour sites and DNA/RNA extraction; support and guidance to researchers and biobanks on accessing, collecting, and using human biospecimens and associated data for health research.

Proper citation: University Health Network Biospecimen Services Core Facility (RRID:SCR_027519) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for performing technically challenging mouse models of cardiovascular disease, such as middle cerebral artery occlusion (MCAO) stroke model, coronary artery ligation model of myocardial ischemia, femoral artery ligation model of peripheral artery disease, and partial carotid artery ligation model of disturbed blood flow.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Surgical Models Core Facility (RRID:SCR_027497) Copy   

•   Source: SciCrunch Registry

https://pmlivingbiobank.uhnresearch.ca/

Core provides services for the use of patient-Derived tumor Organoid (PDO) model.Organoid models are derived from patient-derived xenograft tissues, primary tumors, and metastatic patient tissues. PMLB organoid repository includes models generated from colorectal, pancreatic, and lung cancer tissues.

Proper citation: University Health Network Princess Margaret Living Biobank PDO Core Facility (RRID:SCR_027530) Copy   

•   Source: SciCrunch Registry

https://bhpc.uhnresearch.ca/

Core provides services including Basic High-Throughput Sequencing Analysis, Advanced Data Analysis, High Performance Computing.

Proper citation: University Health Network Bioinformatics and High Performance Computing HPC Core Facility (RRID:SCR_027532) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for generating AAV particles for cardiovascular studies. The CCDS Virus Production Core offers the production of either pre-made (ex. AAV8-GFP, AAV8 mPCSK9 D377Y) or custom AAVs.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Virus Production Core Facility (RRID:SCR_027498) Copy   

•   Source: SciCrunch Registry

https://sttarr.ca/

Offers services to support studies in medical fields across oncology, cardiology, metabolic diseases, radiotheranostics and more.Helps with study design to final data analysis, including GLP-compliant histopathology services.

Proper citation: University Health Network Spatio-Temporal Targeting and Amplification of Radiation Response Core Facility (RRID:SCR_027531) Copy   

•   Source: SciCrunch Registry

http://www.aomf.ca

Core offers services in optical microscopy experiments including: confocal, multiphoton, super-resolution, FRAP, FRET, live-cell timelapse, whole-slide scanning, image analysis and more.

Proper citation: University Health Network Advanced Optical Microscopy Core Facility (RRID:SCR_027535) Copy   

•   Source: SciCrunch Registry

https://www.med.uvm.edu/bsr/home

Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

Proper citation: University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493) Copy   

•   Source: SciCrunch Registry

https://kdtflow.uhnresearch.ca/

Core offers cell sorting and flow cytometry services. Provided instruments include BD FACS Canto II, Beckman Cytoflex LX, BD FACS ARIA III, AutoMacs Cell Separator.

Proper citation: University Health Network Krembil Discovery Tower Flow Cytometry Core Facility (RRID:SCR_027529) Copy   

•   Source: SciCrunch Registry

https://www.research.pitt.edu/western-pennsylvania-quantum-information-core

Core is equipped with suite of cryostats and measurement systems for probing electrical, magnetic, and quantum properties at cryogenic temperatures. Sample preparation capabilities include tools for wafer processing, nanomaterial transfer, and inert atmosphere handling. Deposition systems support thin film growth and surface treatment using a variety of techniques. Wirebonding and related sample preparation tools enable precise device packaging and integration, supporting a broad range of experimental workflows in quantum and nanoscale science.

Proper citation: University of Pittsburgh Western Pennsylvania Quantum Infrastructure Core Facility (RRID:SCR_027582) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/light-microscopy/

Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.

Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy   

•   Source: SciCrunch Registry

https://www.houstonmethodist.org/academic-institute/research/cores/

Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.

Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy   

•   Source: SciCrunch Registry

https://rcgd.isr.umich.edu/research/facilities/zajonc-lab/

Core provides researchers with facilities to conduct experimental research, particularly within the Research Center for Group Dynamics (RCGD) and across the U-M campus. The labs offer adaptable room configurations, specialized software like E-Prime and z-Tree, and shared access to cutting-edge technology, including a new Virtual Reality (VR) Lab, to support a range of interdisciplinary research projects focused on human social behavior and dynamics.

Proper citation: University of Michigan Robert B. Zajonc Experimental Lab Core Facility (RRID:SCR_027478) Copy   

•   Source: SciCrunch Registry