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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Crystallography and NMR System (CNS)
 
Resource Report
Resource Website
1+ mentions
Crystallography and NMR System (CNS) (RRID:SCR_014223) CNS software application, data processing software, software resource, software toolkit, data visualization software Software designed to provide a multi-level hierachical approach for the most commonly used algorithms in macromolecular structure determination. Features include heavy atom searching, experimental phasing (including MAD and MIR), density modification, crystallographic refinement with maximum likelihood targets, and NMR structure calculation using NOEs, J-coupling, chemical shift, and dipolar coupling data. Modules, libraries, utility programs, tutorials, and a syntax manual are available on the website. structure determination, software suite, macromolecular structure determination, data visualization software, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Yale University; Connecticut; USA
PMID:9757107 Available to academic institutions, Request form must be submitted biotools:cnssolve https://bio.tools/cnssolve SCR_014223 Crystallography and NMR System 2026-02-17 10:02:08 8
OpenWalnut
 
Resource Report
Resource Website
OpenWalnut (RRID:SCR_014157) data visualization software, data processing software, software application, software resource Open source tool for multi-modal medical and brain data visualization. It is a tool for the scientific user and a powerful framework for the visualization researcher. It is written in Standard C++ and uses a number of portable libraries (e.g. Qt, Boost and OpenSceneGraph). It runs on common GNU/Linux operating systems, Mac OSX and Windows. open source, data visualization software, brain data, medical tool is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
Free, Available for download, Freely available http://www.openwalnut.org
https://sources.debian.org/src/openwalnut-qt4/
SCR_014157 2026-02-17 10:02:42 0
PsyGeNET
 
Resource Report
Resource Website
10+ mentions
PsyGeNET (RRID:SCR_014406) software application, data or information resource, data processing software, data analysis software, database, software resource Knowledge platform on psychiatric disorders and their genes. Resource for exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of database and set of analysis tools and is the result of the integration of information from DisGeNET and data extracted from the literature by text mining, followed by curation by domain experts. psychiatric disease, associated gene, database, analysis tool, bio.tools is used by: DisGeNET
is listed by: Debian
is listed by: bio.tools
Psychiatric disorder DOI:10.1093/bioinformatics/btv301 Available for the research community biotools:psygenet2r https://bio.tools/psygenet2r SCR_014406 Psychiatric disorders Gene association NETwork, Psychiatric disorders Gene association Network 2026-02-17 10:02:35 11
ImageMagick
 
Resource Report
Resource Website
100+ mentions
ImageMagick (RRID:SCR_014491) image processing software, software application, data processing software, software resource Software suite for creating, editing, composing, and converting bitmap images. It can read and write images in over 200 formats including PNG, JPEG, JPEG-2000, GIF, TIFF, DPX, EXR, WebP, Postscript, PDF, and SVG. The user can use this software to resize, flip, mirror, rotate, distort, shear and transform images, adjust image colors, apply various special effects, or draw text, lines, polygons, ellipses and Bézier curves. image editing, image processing software, image analysis software, bitmap, adjust image colors, bezier curves is listed by: Debian Restricted https://sources.debian.org/src/imagemagick/ SCR_014491 2026-02-17 10:02:12 133
SCRATCH
 
Resource Report
Resource Website
100+ mentions
SCRATCH (RRID:SCR_014291) data access protocol, production service resource, analysis service resource, service resource, software resource, web service Web protein structure and structural feature prediction server.Software suite includes predictors for secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts and tertiary structure. User provides amino acid sequence and selects desired predictions, then submits to the server. Protein predictor, secondary structure, relative solvent accessibility, disordered regions, domains, disulfide bridges, single mutation stability, residue contacts versus average, individual residue contacts, tertiary structure prediction, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:15980571 Free, Freely available biotools:scratch https://bio.tools/scratch http://www.igb.uci.edu/servers/psss.html SCR_014291 Scratch Protein Predictor 2026-02-17 10:02:09 136
NNcon
 
Resource Report
Resource Website
1+ mentions
NNcon (RRID:SCR_014292) software tool, prediction Protein contact map prediction is useful for protein folding rate prediction, model selection and 3D structure prediction. Here we describe NNcon, a fast and reliable contact map prediction server and software. NNcon was ranked among the most accurate residue contact predictors in the Eighth Critical Assessment of Techniques for Protein Structure Prediction (CASP8), 2008. text mining objective, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:19420062 biotools:nncon https://bio.tools/nncon http://casp.rnet.missouri.edu/nncon.html SCR_014292 2026-02-17 10:02:33 2
RepeatScout
 
Resource Report
Resource Website
500+ mentions
RepeatScout (RRID:SCR_014653) software application, data processing software, algorithm resource, data analysis software, software resource, sequence analysis software Algorithm used to identify de novo repeat families in newly sequenced genomes. Repeat libraries for C. briggsae, M. muscles (X chromosome), R. novegicus (X chromosome), armadillo, H. sapiens (X chromosome), and various other mammals created using RepeatScout are available on the main site., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. algorithm, sequence analysis, repeat, genome sequence, de novo, repeat family, repeat library, bio.tools is used by: RepeatModeler
is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:15961478 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:RepeatScout, biotools:RepeatScout https://bio.tools/RepeatScout
https://bio.tools/RepeatScout
https://bio.tools/RepeatScout
SCR_014653 2026-02-17 10:02:40 815
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) data analysis software, software application, data processing software, software resource Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-17 10:02:39 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) software application, data processing software, data analysis software, software resource, sequence analysis software Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks
https://bio.tools/cufflinks
https://sources.debian.org/src/cufflinks/
SCR_014597 2026-02-17 10:02:38 8838
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) software application, data processing software, data analysis software, software resource, sequence analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka
https://sources.debian.org/src/prokka/
https://sources.debian.org/src/prokka/
SCR_014732 2026-02-17 10:02:41 4876
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) software application, data processing software, data analysis software, software resource, sequence analysis software Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-02-17 10:02:45 1
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE data or information resource, narrative resource, wiki Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-02-17 10:02:46 16
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) software application, data processing software, data analysis software, software resource, sequence analysis software, data visualization software Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview
https://sources.debian.org/src/seaview/
SCR_015059 2026-02-17 10:02:46 1777
LTR_Finder
 
Resource Report
Resource Website
500+ mentions
LTR_Finder (RRID:SCR_015247) data access protocol, production service resource, analysis service resource, service resource, software resource, web service Web software capable of scanning large-scale sequences for full-length LTR retrotranspsons., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Long Terminal Repeat retrotransposons, Long Terminal Repeat, retrotransposon prediction, genome sequences, LTR prediction, LTR structure prediction, DNA sequence, biotools is listed by: Debian
is listed by: bio.tools
Fudan University ;
Shanghai ;
China
PMID:17485477 THIS RESOURCE IS NO LONGER IN SERVICE SCR_020944, biotools:ltr_finder https://bio.tools/ltr_finder SCR_015247 LTR Finder 2026-02-17 10:02:48 795
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) software application, data processing software, data analysis software, software resource, sequence analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX
https://bio.tools/MeroX
https://bio.tools/MeroX
SCR_014956 2026-02-17 10:02:45 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) software application, data processing software, algorithm resource, data analysis software, software resource Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Swiss National Science Foundation ;
Marie Curie International Outgoing Fellowship
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco
https://bio.tools/busco
https://sources.debian.org/src/busco/
SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-02-17 10:02:46 7284
GIIRA
 
Resource Report
Resource Website
1+ mentions
GIIRA (RRID:SCR_015507) software application, data processing software, data analysis software, software resource, sequence analysis software Gene prediction method that identifies potential coding regions based on the mapping of reads from an RNA-Seq experiment. gene prediction, rna seq, coding region, potential coding region is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btt577 Available for download OMICS_07360 http://www.rki.de/EN/Content/Institute/DepartmentsUnits/JuniorGroups/JRG4.html
https://sources.debian.org/src/giira/
SCR_015507 2026-02-17 10:02:52 3
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) software tool, data visualization tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-02-17 10:02:36 41
TISSUES
 
Resource Report
Resource Website
10+ mentions
TISSUES (RRID:SCR_015665) data or information resource, database, web application, software resource Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. tissue expression, proteomic, transcriptomic, text-mining, brenda tissue ontology, protein identifier, bio.tools uses: BRENDA Tissue and Enzyme Source Ontology
is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation NNF14CC0001;
NCI U54 CA189205-01;
CSIRO’s OCE Science Leader program
PMID:26157623 Freely available, Free, Available for download biotools:tissues https://bio.tools/tissues SCR_015665 TISSUES: Tissue Expression Database, Tissue Expression Database 2026-02-17 10:02:35 42
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) software application, data processing software, data analysis software, source code, software resource, sequence analysis software Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2
https://bio.tools/hisat2
https://sources.debian.org/src/hisat2/
SCR_015530 HISAT 2026-02-17 10:03:17 17595

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