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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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https://depressioncenter.org/research-services/data-design-core

Core staff provides personalized consultations, knowledge and resources focused on helping investigators leverage secondary data to advance their mental health research. Offers consultations and guide in areas:Identifying secondary data sources for mental health studies,Data preparation (e.g., merging/appending data, preparing variables for analysis), Developing analysis plan, including pre-registration, Statistical analysis.

Proper citation: University of Michigan Eisenberg Family Depression Center Data and Design Core Facility (RRID:SCR_027335) Copy   


https://www.janelia.org/support-team/janelia-experimental-technology

Core team designs, builds and tests instruments, tools, and software that enable novel scientific investigation. Offers expertise in Data acquisition and analysis; Machine vision and image processing; Precision machining; Embedded systems design and programming; Laser, microscopy, and optical imaging systems engineering; Custom circuit design; Novel sensor systems; Lab automation, robotics and motion control; Mechanical design, machined and/or fabricated components and assemblies; Process automation.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Janelia Experimental Technology jET Core Facility (RRID:SCR_027301) Copy   


https://www.augusta.edu/cancer/research/shared-resources/biorepository/

Core provides collection, annotation, and storage solutions. This Biorepository is also home to a state-wide resource, the Biorepository Alliance of Georgia for Oncology (BRAG-Onc), which functions to collect samples from 6 participating sites across the State to represent the diversity of cancer patients within the State and to enhance cancer research in Georgia.Tissue specimens are fast-frozen in vapor phase liquid nitrogen to preserve their integrity and stored in large cryofreezers at -170 to -190°C. Blood is routinely separated into serum or plasma and buffy coats prior to freezing. Blood derivatives are stored at -70 to -80°C. The freezers are monitored constantly and are connected to an alarm system to ensure that the low temperatures are maintained.

Proper citation: Augusta University Georgia Cancer Center Biorepository Core Facility (RRID:SCR_027271) Copy   


https://www.augusta.edu/research/core/human-physiology.php

Core provides services including body/bone composition, comprehensive assessments of cardiovascular health (conduit vessel, microvascular, and central arterial stiffness), comprehensive assessment of lung health (spirometry, diffusion, lung clearance index, exhaled NO), and metabolic/exercise testing. Expanded core services in humans include oral glucose tolerance testing and continuous glucose monitoring, 24h ambulatory blood pressure monitoring, and assessments of autonomic nervous system, cognitive function, mitochondrial function, intramuscular fat, and electrocardiograms.

Proper citation: Augusta University Human Physiology Core Facility (RRID:SCR_027270) Copy   


https://www.crukscotlandinstitute.ac.uk/cruk-si-research/laboratory-operations/scientific-services.html

Offers processing fixed tissue for paraffin-embedded histology, cryo-microtomy, cell pellet processing, H+E staining and special histology stains or cellular material supplied. Immunohistochemistry, immunofluorescence and in-situ hybridisation service is available along with the capability to provide digital scanning and analysis. Many other techniques such as provision of tissue microarrays and other staining techniques such as TUNEL can be provided or set-up as required.

Proper citation: Cancer Research UK Scotland Institute Histology Core Facility (RRID:SCR_027306) Copy   


https://emfacility.science.oregonstate.edu/

Core offers negative staining of protein, tissue processing including dehydration, fixation, staining and utra-microtomy, image biological samples at 80 keV on Generation 2 Titan with Rio CMOS side mount camera for low magnification too high magnification shots of cellular structures. Can also rapidly screen grids with Helios STEM in SEM capability. Provides Helios with auto slicenview and fully licensed Avizo for rendering 3D images of cells.

Proper citation: Oregon State University Electron Microscopy Core Facility (RRID:SCR_027308) Copy   


https://www.crukscotlandinstitute.ac.uk/advanced-technologies/deep-phenotyping.html

Core offers comprehensive pathologist-led spatial biology service comprising spatial proteomic, transcriptomic, and multiomic experimental design, including platform and panel selection, assay development, image acquisition, and digital image processing. The facility houses 2x Ventana Discovery Ultra autostainers, 2x 10 x Genomics Xenium platforms, a Lunaphore COMET, an Akoya PhenoImager, an Akoya PhenoCycler, an Olympus VS200 slide scanner and a Visiopharm image analysis suite.

Proper citation: CRUK Scotland Institute Deep Phenotyping Advanced Technology Core Facility (RRID:SCR_027366) Copy   


https://www.crukscotlandinstitute.ac.uk/advanced-technologies/molecular-technology.html

Core provides Next Generation Sequencing (NGS) services and Single Cell services predominantly focussing on single cell RNAseq. Processes samples for variety of cancer associated projects, in both mouse and human derived materials. Offers full end-to-end service, from initial study design and planning, through sample QC, full library preparation, sequencing and data return. Offers range of standard molecular tests covering, plasmid purifications, Sanger sequencing and mycoplasma screening.

Proper citation: Cancer Research UK Scotland Institute Molecular Technology Service Core Facility (RRID:SCR_027368) Copy   


https://www.augusta.edu/cancer/research/shared-resources/bioinformatics/

Georgia Cancer Center's Bioinformatics Core provides expertise in integrative computational based analysis solutions to basic, clinical, and translational research applications. Services include study design, analysis, and interpretation that may involve interaction with industry, government, and regulatory agencies in the areas of Clinical trials, Epidemiology, laboratory studies, in addition to data mining using local and national databases for hypotheses generation and scientific investigation.

Proper citation: Augusta University Bioinformatics Shared Resource Core Facility (RRID:SCR_027372) Copy   


https://www.ucl.ac.uk/lifesciences-faculty/laboratory-molecular-cell-biology/research/platforms-and-facilities/electron-microscopy

Electron microscopy facility specialising in cell biological electron microscopy for basic and medical research applications.

Proper citation: University College London LMCB Electron Microscopy Core Facility (RRID:SCR_027340) Copy   


https://imss.lnma.mx/inicio.php

Core provides optical microscopy and histology services.

Proper citation: Mexican Social Security Institute National Laboratory of Advanced Microscopy IMSS Core Facility (RRID:SCR_027351) Copy   


https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/liafq/

Laboratory for Physicochemical Analysis of IQ-UNICAMP houses equipment for a range of analytical techniques:Thermal Analysis comprises techniques that measure the physical or chemical properties of a substance, or its reaction products, under controlled temperature variation;Atomic Spectrometry enables multi-element determination in solution samples;Elemental Analysis is used to determine the Carbon, Hydrogen, and Nitrogen content in solid and viscous samples.Nitrogen Physisorption is a technique used to determine the surface area and pore size of solid materials.

Proper citation: State University of Campinas LIAFQ-IQ Laboratory of Physicochemical Analysis Core Facility (RRID:SCR_027389) Copy   


https://medresearch.umich.edu/labs-departments/labs/nucleic-acid-therapeutics

Nucleic Acid Therapeutics Core accelerates the development of gene-targeted therapies by providing custom oligonucleotide synthesis, expert consultation, and platform for cross-disciplinary collaboration.

Proper citation: University of Michigan Medical School Nucleic Acid Therapeutics Core Facility (RRID:SCR_027422) Copy   


https://vrlab.isr.umich.edu/

Core provides flexible systems with built-in support for biometric data collection, dyadic interactions, and reproducible protocols. Provides access to pipelines that support reproducibility, custom data annotation, and seamless handoff to analysis tools in R, Python, and more. Provides access to IRB-ready templates and documentation, along with tested participant safety protocols and secure data management systems.

Proper citation: University of Michigan ISR-VR Lab Core Facility (RRID:SCR_027421) Copy   


https://www.lerner.ccf.org/cores/light-microscopy/

Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.

Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy   


https://www.houstonmethodist.org/academic-institute/research/cores/

Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.

Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy   


https://rcgd.isr.umich.edu/research/facilities/zajonc-lab/

Core provides researchers with facilities to conduct experimental research, particularly within the Research Center for Group Dynamics (RCGD) and across the U-M campus. The labs offer adaptable room configurations, specialized software like E-Prime and z-Tree, and shared access to cutting-edge technology, including a new Virtual Reality (VR) Lab, to support a range of interdisciplinary research projects focused on human social behavior and dynamics.

Proper citation: University of Michigan Robert B. Zajonc Experimental Lab Core Facility (RRID:SCR_027478) Copy   


https://icahn.mssm.edu/research/resources/deans-cores/neuropathology

Provides access to collection of human postmortem brain tissues, including fresh, frozen, and formalin-fixed paraffin-embedded (FFPE) specimens, along with detailed clinical histories and neuropathological assessments. Available histology services include processing and embedding, slide sectioning for FFPE and cryosections, immunohistochemistry (IHC), immunofluorescence (IF), and advanced RNA assays such as RNAscope, BaseScope, and miRscope. High-resolution digital slide imaging is performed using the GT450 scanner. CoRE scientists also collaborate with investigators and trainees to support project development, method optimization and troubleshooting, data analysis.

Proper citation: Icahn School of Medicine at Mount Sinai Neuropathology Brain Bank and Research CoRE Facility (RRID:SCR_027565) Copy   


https://icahn.mssm.edu/research/human-immune-monitoring-center

Core provides team of experts in the characterization of immune profiles and treatment responses across a diverse range of diseases, such as cancer, autoimmunity, allergy, and neuro-immune disorders. Offers equipment in the field for research at Genomic, cellular and proteomic analysis. Develops assays to balance innovation with protocols and operating procedures to ensure data quality and reproducibility.

Proper citation: Icahn School of Medicine at Mount Sinai Human Immune Monitoring Center Core Facility (RRID:SCR_027571) Copy   


https://www.goodmancancer.ca/en/mcgill-integrated-core-for-animal-modeling-micam

Animal models of human disease are an invaluable research resource in the medical research community.Core provides services in the creation of animal models to the local research community and clients across Canada.

Proper citation: McGill University Integrated Core for Animal Modeling Core Facility (RRID:SCR_027541) Copy   



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