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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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https://www.cshl.edu/research/cancer/microscopy/

Provides access to microscopes, technical advice and expertise in preparing cells or tissues for immunofluorescence/confocal microscopy, live cell imaging, super resolution imaging, transmission electron microscopy, and immunoelectron microscopy.

Proper citation: Cold Spring Harbor Laboratory Microscopy Shared Resource Core Facility (RRID:SCR_023023) Copy   


https://teamhubottawa.com/

Core research facilities include BioImaging Research Node which houses commercial and custom imaging systems and is focused on optical imaging; Tissue Engineering and Biomaterials Testing Research Node equipped with microfluidics 3D bioprinter and mechanical testers, which facilitate development of artificial 3D biological tissue models and biomechanical testing of different biomaterials and biomedical samples; Biochemistry and Molecular Biology Research Node which houses hypoxia chamber and systems for characterization and quantification of proteins, peptides, and nucleic acids; Cellular Biology Research Node to support development and use of 3D tissue models.It houses instruments including flow cytometer for phenotyping and performing functional testing of cells and bacteria, Seahorse Analyzer for evaluation of metabolic activity of cells, and Incucyte for live cell imaging of cells and tissues in culture.

Proper citation: Carleton University Tissue Engineering and Applied Materials Hub Core Facility (RRID:SCR_022968) Copy   


https://www.unmc.edu/publichealth/centers/ccorda/index.html

Provides advance clinical, translational and public health research at UNMC and in the community and region. Provides expertise in quantitative sciences, including biostatistics, epidemiology, and health services research, and coordinates collaborative design, planning, conduct, analysis and interpretation of laboratory, clinical, and public health research studies.Provides educational training opportunities for graduate students and educational opportunities for public health, clinical, and translational investigators.

Proper citation: University of Nebraska Medical Center Center for Collaboration on Research Design and Analysis Core Facility (RRID:SCR_022860) Copy   


https://med.stanford.edu/obrienurology/research.html

Core leverages infrastructure of Stanford Urology and Pathology Departments to provide services to benefit O’Brien Center investigators in CAIRIBU Network. Procures and provides biospecimens, including fresh, freshly-frozen, and formalin-fixed paraffin-embedded (FFPE) prostate issues.Provides tissue characterization services, including histology, tissue microarrays, laser microdissection, and multiplex immunohistochemistry (IHC) using MIBI-TOF (Multiplexed Ion Beam Imaging by Time of Flight). Stores and provides access to images including prostate MRIs, whole-mount histology and IHC, and MIBI-TOF data, as well as integrated multiscale data platform.

Proper citation: Stanford University School of Medicine O’Brien Urology Research Center Biospecimen/Bioimaging Core Facility (RRID:SCR_022852) Copy   


http://GeneEditing.wustl.edu/

Provides support with technologies for cell and animal model needs. Services are ranging from CRISPR reagents with or without validation, to cancer/iPS cell line modification or animal model creation. Works closely with mouse cores from design, reagent validation to genotyping, process improvement and troubleshooting, when necessary. Provides next-generation sequencing (NGS) based human cell authentication and NGS-based genotyping services and general molecular biology assistance. Offers to culture, bank and store primary fibroblasts and renal epithelial cells from patient samples for investigators, and iPSC reprogramming service is provided from fibroblasts, RECs as well as peripheral blood mononuclear cells. Provides differentiation services on growing list of cell types.

Proper citation: Washington University School of Medicine Genome Engineering and Stem Cell Center Core Facility (RRID:SCR_023243) Copy   


https://cancer.dartmouth.edu/scientists-researchers/microscopy-resource

Light microscopy imaging facility within Dartmouth Cancer Center. Services offered include confocal microscopy with Airyscan, multispectral imaging slide scanner, high thoughput brightfield and multichannel fluorescence microscopy of live cells, multichannel TIRF microscopy, photopatterning and microfabrication.

Proper citation: Dartmouth College Microscopy Shared Resource Core Facility (RRID:SCR_023478) Copy   


https://www.lifespan.org/centers-services/molecular-pathology-core-laboratory

Core of COBRE Center at department of Pathology located on sixth floor of Aldrich building at Rhode Island Hospital.Provides services, instrumentation, training and support. Equipment includes ArcturusXT laser capture microdissector, Stratagene MX3005p realtime PCR instrument, BioRad iCycler, Agilent Bioanalyzer, Olympus fluorescence-capable microscope with image analysis software, Ventana Discovery immunohistochemistry processor, microtome, cryostat, Beecher tissue arrayer and Aperio ScanScope.Tissue bank has 40 cu ft of ultra-low freezer space and provides human tumor tissue samples to all interested investigators who have received IRB approval for academic testing and research.Services include Tissue Sample Processing,Histology,Immunohistochemistry,Digital slide scanning by Aperio ScanScope,Tissue Microarrays,DNA/RNA extraction, Microdissection,Macrodissection verification by pathologist,Digital image analysis,Visium Spatial Gene Expression Assay,RNAscope Assay,Enzyme Linked Immunosorbent Assays (ELISAs),Technical assistance,Pathologist consultation,Technical assistance, Equipment use and training.

Proper citation: Rhode Island Hospital Molecular Pathology Core Facility (RRID:SCR_023490) Copy   


https://hpcc.stanford.edu/

Academic cost recovery center, operates number of HPC clusters to enable larger simulations, deeper analyses, and faster computation times than are possible using computers available to individual researchers. Provides mass data storage and archival systems to store data.

Proper citation: Stanford University High Performance Computing Center Core Facility (RRID:SCR_023411) Copy   


https://maf.stanford.edu/

Facility is equipped with JEOL JXA-8230 SuperProbe electron microprobe. Electron microprobe measures elemental compositions of solid samples by detecting the X-rays emitted on excitation by focused electron beam, down to spatial resolution of about 1 micron. All elements heavier than beryllium can be detected, at concentrations as low as 10s of ppm. Highly quantitative analyses are made using 5 wavelength dispersive X-ray spectrometers (WDS) with calibrations based on known standard materials. Compositional images (maps) can readily be obtained with backscattered electrons (sensitive primarily to mean atomic number), or with WDS or EDS X-ray data. The instrument is adjacent to the Stanford Nanocharacterization Laboratory (SNL), at the west end of the first floor of the McCullough Building.

Proper citation: Stanford Microchemical Analysis Core Facility (RRID:SCR_023256) Copy   


https://sdssemf.stanford.edu/

Provides instruments for solid, aquouse and gas sample analyses, quantitative analysis, technical expertise to members of Stanford community.

Proper citation: Stanford Environmental Measurements Core Facility (RRID:SCR_023255) Copy   


https://www.crg.eu/en/programmes-groups/protein-technologies-unit

Provides technology platform to perform protein production and automated processes in context of biomolecular and biochemical screening assays.Through staff assisted screening, users have access to equipment including liquid handlers, plate readers and small molecule libraries.Unit is aimed at supporting the researchers of the CRG institute by purchasing, seeking and maintaining valuable stocks of clones and strains.

Proper citation: Centre for Genomic Regulation Protein Technologies Unit Core Facility (RRID:SCR_023376) Copy   


https://www.crg.eu/en/programmes-groups/tissue-engineering-unit-0

Provides latests technologies for stem cell biology, stem cell differentiation, organoid formation and induced pluripotent stem cells.Tissue Engineering platform works in collaboration with Biomolecular Screening and Protein Technologies Unit to provide CRISPR/Cas9 genome editing technology service.Unit also includes Histology In-house Service (only for PRBB residents) provides histopathological analysis required for analysing tissues from research performed in in vivo models. Histology In-house Service performs and optimizes histological processing and analysis of tissue, from experimental animal models and human origin.Provides mentoring and training in common histological techniques.

Proper citation: Centre for Genomic Regulation Tissue Engineering Unit Core Facility (RRID:SCR_023375) Copy   


https://sibl.stanford.edu/

Stable Isotope Biogeochemistry Laboratory at Stanford University's School of Earth Sciences provides analytical facilities and technical expertise to members of Stanford community who need to determine stable isotope ratios of variety of organic and inorganic materials from both terrestrial and marine environments.

Proper citation: Stanford Stable Isotope Biogeochemistry Laboratory Core Facility (RRID:SCR_023253) Copy   


https://www.crg.eu/en/programmes-groups/genomics-unit

Supports next generation sequencing technologies and provides several next generation sequencing instruments. Several high-throughput technologies have been implemented to assess differential expression, inter-individual genetic variation, microRNA discovery, genome sequencing, targeted resequencing, epigenetic profiling and identification of binding sites of DNA or RNA-associated proteins.

Proper citation: Centre for Genomic Regulation Genomics Unit Core Facility (RRID:SCR_023374) Copy   


https://neuroscience.stanford.edu/research/neuroscience-community-labs/visualization-lab

Used to explore new visualization technologies related to study of brain.Provides equipment and expertiese to help with project setup and planning. Hosts adaptive optics system that uses optical principles originally developed for visualizing distant stars to enable high resolution imaging of retina in human subjects.

Proper citation: Stanford Visualization Laboratory Core Facility (RRID:SCR_023251) Copy   


https://www.crg.eu/en/programmes-groups/crgupf-flow-cytometry-unit

Flow cytometry studies optical parameters emitted by particles (cells, cell fractions). Flow cytometers can study a series of parameters of individual particles simultaneously, quickly and on a large number of individualized particles in suspension. Flow cytometers use lasers as a source of light excitement; therefore, it must be possible to mark the particles with one or more fluorescent substances. Information is also collected regarding the size and structural complexity of each particle. This multiparameter study of each particle enables us to analyse subpopulations in complex samples through electronic sorting. Some cytometers are also equipped with sorting and collection modules for particles of interest. The most important applications of flow cytometry include those relating to the study of cell surface receptors, nuclear and cytoplasmic antigens, DNA content, enzyme activity, cell integrity and membrane permeability and calcium flows. The Unit currently hosts five analyzers and two sorters, and is therewith the largest Becton Dickinson site in Spain. The sorters are operated by the facility personnel, who also support the users in experimental design and data analysis. The analyzers are operated by the users themselves, after they have been trained. The facility personnel helps with the experimental design and supervises and monitors the experiments when necessary.

Proper citation: Centre for Genomic Regulation Flow Cytometry Unit Core Facility (RRID:SCR_023372) Copy   


https://neuroscience.stanford.edu/research/neuroscience-community-labs/gene-vector-and-virus-core

Core centralizes process of producing and distributing viral vectors and cDNA plasmids.

Proper citation: Stanford Neuroscience Gene Vector and Virus Core Facility (RRID:SCR_023250) Copy   


https://stanford.ilabsolutions.com/service_center/show_external/21/biomaterials-and-advanced-drug-delivery-bioadd-laboratory

Provides creation of biomaterials and drug delivery agents, expertise toward designing and analyzing biomaterials, development of drug delivery devices and formulations, pharmacokinetic and pharmacodynamic studies, and development of materials for biomedical applications.

Proper citation: Stanford University Biomaterials and Advanced Drug Delivery Laboratory Core Facility (RRID:SCR_023406) Copy   


https://web.stanford.edu/group/chem-optics/

Houses optical spectroscopy instruments including Fluorolog 3 Fluorimeter,Vertex 70 FTIR with RAM II Raman accessory, Cary 6000i UV/Vis/NIR Spectrometer.

Proper citation: Stanford University Chemistry Department Optics Core Facility (RRID:SCR_023405) Copy   


https://med.stanford.edu/lcgm.html

Provides support and services to clinical investigators including consulting, technology transfer, process and analytical development, clinical manufacturing and regulatory affairs.

Proper citation: Stanford University School of Medicine Laboratory for Cell and Gene Medicine Core Facility (RRID:SCR_023403) Copy   



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