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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SAMTOOLS
 
Resource Report
Resource Website
10000+ mentions
SAMTOOLS (RRID:SCR_002105) SAMtools sequence analysis software, data processing software, data analysis software, software toolkit, software application, software resource Original SAMTOOLS package has been split into three separate repositories including Samtools, BCFtools and HTSlib. Samtools for manipulating next generation sequencing data used for reading, writing, editing, indexing,viewing nucleotide alignments in SAM,BAM,CRAM format. BCFtools used for reading, writing BCF2,VCF, gVCF files and calling, filtering, summarising SNP and short indel sequence variants. HTSlib used for reading, writing high throughput sequencing data. Samtools, BCFtools, HTSlib, next generation sequencing, nucleotide alignments, sequence variant, genomic, c, perl, read, alignment, nucleotide, sequence, data, process, sam, bam, cram, vcf, bcf, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: ROSE
is used by: Fcirc
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SNVer
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Platypus
is related to: shovill
is related to: pysam
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is parent organization of: SAMtools/BCFtools
is required by: RelocaTE
is required by: Wessim
is required by: SL-quant
is required by: smMIPfil
Wellcome Trust ;
NHGRI U54 HG002750
PMID:19505943
PMID:21903627
DOI:10.1093/bioinformatics/btp352
Free, Available for download, Freely available SCR_018682, biotools:samtools, OMICS_01074, nlx_154607, OMICS_00090 https://github.com/samtools/samtools
https://github.com/samtools/htslib
https://bio.tools/samtools
https://sources.debian.org/src/samtools/
http://samtools.sourceforge.net/ SCR_002105 samtools, Samtools, Sequence Alignment Map TOOLS, SAMtools, SAM tools 2026-02-14 02:00:18 30156
BLASTN
 
Resource Report
Resource Website
10000+ mentions
BLASTN (RRID:SCR_001598) BLASTn data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Web application to search nucleotide databases using a nucleotide query. Algorithms: blastn, megablast, discontiguous megablast. nucleotide, alignment, compare, sequence, genome, blast, transcript, dna sequence is listed by: OMICtools
is listed by: SoftCite
has parent organization: NCBI
works with: Seek and Blastn
works with: RMBlast
PMID:17666756
PMID:18567917
Free, Freely available nlx_153932, OMICS_00990 http://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRAM=blastn&PAGE_TYPE=BlastSearch&LINK_LOC=blasthome SCR_001598 NCBI BLASTN, Nucleotide Blast, Standard Nucleotide BLAST 2026-02-14 02:00:04 19679
Sequencher
 
Resource Report
Resource Website
1000+ mentions
Sequencher (RRID:SCR_001528) Sequencher sequence analysis software sequence analysis software, data processing software, data analysis software, software application, software resource Software for Next-Generation DNA sequencing, Sanger DNA analysis, and RNA sequencing. It contains sequence analysis tools which include reference-guided alignments, de novo assembly, variant calling, and SNP analyses. It has integrated the Cufflinks suite for in-depth transcript analysis and differential gene expression of RNA-Seq data. dna, sequencing, sequence analysis software, NGS, sanger, data visualization is listed by: OMICtools
is listed by: SoftCite
Available for download OMICS_01817 http://genecodes.com/sequencher-features SCR_001528 Sequencher sequence analysis software 2026-02-14 02:00:05 4965
PLINK
 
Resource Report
Resource Website
10000+ mentions
Issue
PLINK (RRID:SCR_001757) data processing software, data analysis software, software toolkit, software application, software resource Open source whole genome association analysis toolset, designed to perform range of basic, large scale analyses in computationally efficient manner. Used for analysis of genotype/phenotype data. Through integration with gPLINK and Haploview, there is some support for subsequent visualization, annotation and storage of results. PLINK 1.9 is improved and second generation of the software. gene, genetic, genomic, genotype, phenotype, copy number variant, whole-genome association, population, linkage analysis, whole-genome association study, data management, summary statistics, population stratification, association analysis, identity-by-descent estimation is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: SoftCite
is related to: Whap
is related to: PLINK/SEQ
is related to: Haploview
is related to: MendelIHT.jl
PMID:17701901
DOI:10.1086/519795
Free, Available for download, Freely Available nlx_154200, OMICS_00206, SCR_021271 https://zzz.bwh.harvard.edu/plink/
https://www.cog-genomics.org/plink/1.9/general_usage#cite
https://sources.debian.org/src/plink/
http://pngu.mgh.harvard.edu/~purcell/plink/ SCR_001757 PLINK 1.9, PLINK/SEQ, plink - Whole genome association analysis toolset 2026-02-14 02:00:10 15344
GenABEL
 
Resource Report
Resource Website
500+ mentions
GenABEL (RRID:SCR_001842) software resource, software library, software toolkit THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. R software library for genome-wide association analysis for quantitative, binary and time-till-event traits. r, genome-wide association, single nucleotide polymorphism is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: SoftCite
Centre for Medical Systems Biology; Netherlands ;
Netherlands Genomics Initiative ;
Netherlands Organisation for Scientific Research ;
Russian Foundation for Basic Research
PMID:17384015
DOI:10.1186/1471-2105-11-134
DOI:10.1093/bioinformatics/btm108
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154328, OMICS_00234 http://mga.bionet.nsc.ru/~yurii/ABEL/GenABEL/
https://cran.r-project.org/web/packages/GenABEL/index.html
https://sources.debian.org/src/probabel/
SCR_001842 GenABEL package, R/GENABEL 2026-02-14 02:00:12 506
FreeSurfer
 
Resource Report
Resource Website
10000+ mentions
FreeSurfer (RRID:SCR_001847) FreeSurfer data visualization software, data processing software, software application, software resource, image analysis software Open source software suite for processing and analyzing human brain MRI images. Used for reconstruction of brain cortical surface from structural MRI data, and overlay of functional MRI data onto reconstructed surface. Contains automatic structural imaging stream for processing cross sectional and longitudinal data. Provides anatomical analysis tools, including: representation of cortical surface between white and gray matter, representation of the pial surface, segmentation of white matter from rest of brain, skull stripping, B1 bias field correction, nonlinear registration of cortical surface of individual with stereotaxic atlas, labeling of regions of cortical surface, statistical analysis of group morphometry differences, and labeling of subcortical brain structures.Operating System: Linux, macOS. processing, analysis, human, brain, MRI, image, reconstruction, cortical, surface, fMRI, data is used by: Wisconsin Cortical Thickness Analysis (CTA) Toolbox
is used by: freesurfR
is used by: Automatic Analysis
is used by: NHP Freesurfer
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: Debian
is listed by: SoftCite
is related to: PySurfer
is related to: RFT FDR
is related to: FMRLAB
is related to: TRACULA
is related to: BASH4RfMRI
has parent organization: Harvard University; Cambridge; United States
has plug in: JOSA
works with: NIAG Addiction Data
NCRR U24 RR021382;
NINDS R01 NS052585;
NCRR RR014075
PMID:22248573 Free, Available for download, Freely available nif-0000-00304 https://sources.debian.org/src/freesurfer/
http://www.nitrc.org/projects/freesurfer
http://surfer.nmr.mgh.harvard.edu/fswiki/DownloadAndInstall
SCR_001847 2026-02-14 02:00:12 11817
AStalavista
 
Resource Report
Resource Website
50+ mentions
AStalavista (RRID:SCR_001815) AStalavista data analysis service, analysis service resource, production service resource, service resource, software resource Tool that extracts and displays alternative splicing (AS) events from a given genomic annotation of exon-intron gene coordinates. By comparing all given transcripts, it detects the variations in their splicing structure and identifies all AS events (like exon skipping, alternate donor, etc) by assigning to each of them an AS code. It provides a visual summary of the AS landscape in the analyzed dataset, the possibility to browse the results on the UCSC website or to download them in GTF or ASTA format. You can use AStalavista for any genome by providing your own annotation set, the identifier of your gene(s) of interest, or analyze the AS landscape of reference annotation datasets like Gencode, RefSeq, Ensembl, FlyBase, etc. alternative splicing event, alternative splicing, visualization, genome, transcript is listed by: OMICtools
is listed by: SoftCite
has parent organization: Center for Genomic Regulation; Barcelona; Spain
PMID:17485470 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01943 http://genome.imim.es/astalavista
http://genome.crg.es/astalavista/
SCR_001815 Alternative Splicing transcriptional landscape visualization tool 2026-02-14 02:00:19 83
NIS-Elements
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
NIS-Elements (RRID:SCR_014329) data processing software, data analysis software, software toolkit, software application, software resource Microscope imaging software suite used with Nikon products. NIS-Elements includes software applications for advanced and standard research, documentation, confocal microscopy, and high-content analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. element, microscope imaging software, software suite, nikon is listed by: SoftCite
works with: Nikon ECLIPSE Ti2 inverted microscope
THIS RESOURCE IS NO LONGER IN SERVICE SCR_014329 Nikon Instruments Software Elements, NIS Elements, Nikon Instruments Software 2026-02-14 02:02:39 3462
IMAGIC
 
Resource Report
Resource Website
100+ mentions
IMAGIC (RRID:SCR_014447) data processing software, software application, image processing software, software resource, image analysis software An image analysis software that can process spectra and other multi-dimensional data-sets. The software package is aimed at processing large data sets from (cryo-) electron microscopy, especially in the field of single particle analyses. This software can be used with light and raster-tunneling microscopes, computer tomographs, FT-IR spectrometers and other signal collecting devices. This resource provides three-dimensional data processing and angular reconstitution modules that allow the three-dimensional reconstruction with point-group symmetry from the two dimensional electron microscopy projections. These models aid in the analysis of the macromolecules. image analysis, spectra, multi-dimensional data, macromolecule, 3d processing, tomograph, spectrometer, software environment is listed by: SoftCite PMID:8742718 Commercial, Account needed for download SCR_014447 2026-02-14 02:02:39 217
LSM Image Examiner
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
LSM Image Examiner (RRID:SCR_014344) data management software, software resource, software application Software used to compile images obtained from the Zeiss LSM 510 confocal microscope. The browser can be used for general image archiving and handling and interactive measurement in labs and workgroups. Features include orthogonal sectioning, 3D cut function, 3D view with calculation of single projections, and interactive measurement functions in the overlay dialog, such as scale bar, distance, and area. data management software, image archive, image management, interactive measurement is listed by: SoftCite Available for download http://www.zeiss.com/microscopy/en_us/website/downloads/lsm-image-browser.html http://lsm-image-examiner.software.informer.com SCR_014344 LSM Image Browser 2026-02-14 02:02:37 1508
Definiens Developer XD
 
Resource Report
Resource Website
10+ mentions
Definiens Developer XD (RRID:SCR_014283) software resource A development environment designed to create automated image analysis solutions for segmentation and classification tasks. It delivers quantitative and consistent data for any type of image (e.g., IHC, ISH, IF images in different formats). Developer XD also contains a large library of image analysis algorithms, which users can add to, for whole slide images and tissue microarrays (TMAs). It can be integrated with an existing Tissue Studio installation. development environment, image analysis solution, segmentation, classification, image analysis algorithm library, tissue microarray, whole slide image, tissue studio is listed by: SoftCite SCR_014283 2026-02-14 02:02:58 10
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) data analysis software, software resource, data processing software, software application Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-14 02:02:57 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) sequence analysis software, data processing software, data analysis software, software application, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks
https://bio.tools/cufflinks
https://sources.debian.org/src/cufflinks/
SCR_014597 2026-02-14 02:02:57 8838
Minitab
 
Resource Report
Resource Website
5000+ mentions
Minitab (RRID:SCR_014483) data analysis software, software resource, data processing software, software application A statistical software package that allows the user to import data, create graphs, and perform statistical analysis. It can perform basic statistical tests like descriptive statistics, hypothesis tests, confidence intervals, and normality tests as well as regression and ANOVA and quality assessment. data analysis, statistical analysis, hypothesis, confidence, descriptive is listed by: SoftCite SCR_014483 2026-02-14 02:02:41 5778
COMSOL Multiphysics
 
Resource Report
Resource Website
10+ mentions
COMSOL Multiphysics (RRID:SCR_014767) software resource, simulation software, software application General-purpose software platform for modeling and simulating physics-based problems which accounts for coupled or multiphysics phenomena. The platform includes a set of core physics interfaces for common physics application areas such as structural analysis, laminar flow, pressure acoustics, transport of diluted species, electrostatics, electric currents, heat transfer, and Joule heating. simulation software, software platform, physics, problem solver is listed by: SoftCite Commercially available SCR_014767 2026-02-14 02:02:59 37
CVODE
 
Resource Report
Resource Website
50+ mentions
CVODE (RRID:SCR_014696) data analysis software, software resource, data processing software, software application Solver for stiff and nonstiff ordinary differential equation (ODE) systems (initial value problem), given in explicit form y' = f(t,y), based on Adams and BDF methods. It is one of the programs that makes up the Suite of Nonlinear and Differential/Algebraic Equation Solvers (SUNDIALS)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data analysis software, solver, equation solver, ordinary differential equation, differential equation, stiff, nonstiff is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014696 SUNDIALS CVODE 2026-02-14 02:03:01 56
MedCalc
 
Resource Report
Resource Website
10000+ mentions
MedCalc (RRID:SCR_015044) data analysis software, software resource, data processing software, software application Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis. statistic, statistical analysis, roc curve, reference software is listed by: SoftCite Commercially available, Available for purchase, Trial available SCR_015044 2026-02-14 02:03:04 18070
KaleidaGraph
 
Resource Report
Resource Website
1000+ mentions
KaleidaGraph (RRID:SCR_014980) data visualization software, data processing software, data analysis software, software application, software resource Data analysis, graphing, and management application that allows users to import, manipulate, analyze data, and create customized plots. Plots include x-y probability, histogram, box, percentile, horizontal bar, stack bar, column, stack column, polar, and pie. Binned data can be exported to a histogram, step plot, or spike plot. KaleidaGraph works with Windows and Macintosh systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. custom graph, custom plot, publishable graph, publishable plot, data manipulation, curve fitting is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014980 2026-02-14 02:03:00 2788
SEDFIT
 
Resource Report
Resource Website
10+ mentions
SEDFIT (RRID:SCR_018365) data analysis software, software resource, data processing software, software application Software tool for analytical ultracentrifugation developed by Dynamics of Macromolecular Assembly group of Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institute of Biomedical Imaging and Bioengineering, NIH. Used for biophysical analysis of macromolecular assembly. Analytical ultracentrifugation, biophysical analysis, macromolecular assembly, data, analysis, National Institute of Biomedical Imaging and Bioengineering is listed by: SoftCite NIH Free, Available for download, Freely available SCR_018365 SEDFIT version 14.7g 2026-02-14 02:03:34 25
Phyutility
 
Resource Report
Resource Website
10+ mentions
Phyutility (RRID:SCR_018545) data analysis software, software resource, data processing software, software application Command line program that performs analyses or modifications on both trees and data matrices. Software phyloinformatics tool for trees, alignments and molecular data. Used for summarizing and manipulating phylogenetic trees, manipulating molecular data and retrieving data from NCBI. Data matrice analysis, data matrice modification, phyloinformatics, phylogenetic tree, alignment, molecular data manipulation, data analysis is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
is related to: NCBI
NSF Cyberinfrastructure for Phylogenetic Research EF 0331654 PMID:18227120 Free, Freely available OMICS_21687 https://sources.debian.org/src/phyutility/ SCR_018545 2026-02-14 02:03:39 42

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