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http://biobank.charite.de

Integrated healthcare biobank that operates under certified conditions and strict SOPs. Enables biomedical and translational researchers to perform their analyses using high quality biospecimens and data to generate reliable and reproducible research data. Core offers modular biobanking portfolio that can cover workflow from blood collection to storage, including all pre-analytical steps and their documentation. Offers spectrum of additional services ranging from DNA/RNA extraction and virtual microscopy to entire management of sample and data flow for national and international research consortia. Provides secure conventional and automated storage of samples at various temperatures as well as secure data management.

Proper citation: Charite University and Berlin Institute for Health Research Central Biobank Core Facility (RRID:SCR_023495) Copy   

•   Source: SciCrunch Registry

https://www.agilent.com/cs/library/brochures/5990-5596EN.pdf

Agilent 3100 OFFGEL Fractionator performs isoelectric focusing of proteins or peptides in immobilized pH gradient (IPG) gel strips.

Proper citation: Agilent 3100 OFFGEL Fractionator (RRID:SCR_018433) Copy   

•   Source: SciCrunch Registry

https://timothyspringer.org/files/tas/files/biacore3000-instrument.pdf

Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants.

Proper citation: Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) Copy   

•   Source: SciCrunch Registry

http://mbcf.dfci.harvard.edu

Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff.

Proper citation: Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) Copy   

•   Source: SciCrunch Registry

https://sites.dartmouth.edu/toxmetal/program-resources/trace-element-analysis/

Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions.

Proper citation: Dartmouth Trace Element Analysis Core Facility (RRID:SCR_009777) Copy   

•   Source: SciCrunch Registry

https://flow.forsyth.org/

Core offers consulting and support services for detection of different fluorescent parameters simultaneously, RBC contaminated samples, and high throughput analysis using 96 or 384-well plates. Cell sorter allows for collecting cells/particulates of interest, after screening for positively selected markers, downstream applications, and is capable of sorting four separate cell populations simultaneously.

Proper citation: Forsyth Institute Flow Cytometry Core Facility (RRID:SCR_009785) Copy   

•   Source: SciCrunch Registry

https://bioinformatics.forsyth.org/

Core specializes in oral microbial genomics, taxonomy, phylogenetics and the next generation sequence (NGS) data analysis with both in house and cloud high performance computational resource. In addition to supporting funded bioinformatics projects, Bioinformatics Core will also provide computational support to Forsyth and other researchers for processing, analyzing, and interpreting biological data.

Proper citation: Forsyth Institute Bioinformatics Core Facility (RRID:SCR_009783) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/flow-cytometry-core

Core facility that provides the following services: Analytical flow cytometry service, Cell sorting service, Flow cytometry data analysis service, Grant preparation support service, Flow cytometry instrument training, Flow cytometry consultation service. The OHSU Flow Cytometry Shared Resource (FCSR) has operated as a core resource for OHSU Knight Cancer Institute members since 1996 and provides advanced flow cytometry instrumentation, technical expertise and technical services. The FCSR also provides training in data interpretation, experiment design and routine operation to researchers, offering an additional cost-saving option of doing some of the work themselves. Finally, this resource saves valuable investigator time by analyzing specimens and preparing them, if needed.

Proper citation: OHSU Flow Cytometry and Monoclonal Antibody Shared Resource Core Facility (RRID:SCR_009974) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/pharmacokinetics-core

Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations.

Proper citation: OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center

Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.

Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/octri/clinical-and-translational-research-center

Provides nursing, bionutrition, study coordination, and laboratory services and support. Laboratory is designed and equipped to perform both basic and specialized research assays and sample processing in support of translational research studies and trials. Laboratory staff have extensive experience in performance of wide variety of analytical and genetic based assays and procedures.

Proper citation: OHSU Oregon Clinical and Translational Research Center Core Facility (RRID:SCR_009996) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/proteomics-shared-resource

Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.

Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/medicinal-chemistry-core/nmr

Core facility that provides the following services: NMR instrument training. A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.

Proper citation: OHSU Nuclear Magnetic Resonance Core Facility (RRID:SCR_009989) Copy   

•   Source: SciCrunch Registry

https://research.utsa.edu/cores/mspc/

Core provides routine and custom mass spectrometry-based support. Services include High-resolution, high mass accuracy mass analysis (HRMS), Liquid chromatography-mass spectrometry (LC-MS), Proteomics-based analyses.

Proper citation: University of Texas San Antonio Mass Spectrometry and Proteomics Core Facility (RRID:SCR_010151) Copy   

•   Source: SciCrunch Registry

https://rnainnovation.med.upenn.edu/scientific-groups/targeting-core/

Core to support advancement of RNA biotherapeutics via enabling swift and low failure solutions of targeting related aspects. Provides methodologies, equipment, reagents, expertise and support in identification of epitopes and ligands, molecular design and testing of targeting RNA to diverse multitudes of desirable addresses in the body.

Proper citation: University of Pennsylvania Institute for RNA Innovation Targeting Core Facility (RRID:SCR_024573) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/immunehealth/

Core provides infrastructure and technical support for scaling clinical immune profiling of large scale clinical cohorts. Provides biospecimen processing, sample storage, high dimensional immune assays, computational analysis, and project management. Services are only available to investigators and teams whose cohorts have been approved by the Immune Health leadership.

Proper citation: University of Pennsylvania Institute for Immunology and Immune Health I3H Core Facility (RRID:SCR_024574) Copy   

•   Source: SciCrunch Registry

https://www.huck.psu.edu/core-facilities/cryo-electron-microscopy-facility

Cryo-Electron Microscopy Facility houses FEI Titan Krios microscope that offers data collection for life sciences while incorporating materials science applications. Used for creating super high definition 3D images of atoms and molecules. Facility allows for fully automated atomic resolution single particle and high contrast tomography tilt-series data collection. Additional microscopy components permit a full range of materials science applications, including EELS, STEM, and DPC. Facility also houses ThermoFisher Arctica G2.

Proper citation: Pennsylvania State University Huck Institutes Cryo-Electron Microscopy Core Facility (RRID:SCR_024456) Copy   

•   Source: SciCrunch Registry

https://research.pasteur.fr/en/team/human-disease-models-core-facility/

Core Facility produces mice harboring human immune system and provides expertise for possible applications of this model. HIS mice engrafted with human Hematopoietic stem cells are advantageous in vivo models for long term studies in field of human immune cells biology, immune oncology and infectious disease. They constitute small animal model in which to analyze potency and safety of small animal model modulating immune system.

Proper citation: Pasteur Institute Human Disease Models Core Facility (RRID:SCR_023881) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/infectious-disease-aerobiology-core

Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.

Proper citation: Tulane University TNBRC Infectious Disease Aerobiology Core Facility (RRID:SCR_024608) Copy   

•   Source: SciCrunch Registry

https://tnprc.tulane.edu/clinical-pathology-core

Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.

Proper citation: Tulane University TNBRC Clinical Pathology Core Facility (RRID:SCR_024609) Copy   

•   Source: SciCrunch Registry