Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
T Cell ExTRECT Resource Report Resource Website |
T Cell ExTRECT (RRID:SCR_027742) | software toolkit, software resource, source code | Software R package to calculate T cell fractions from WES data from hg19 or hg38 aligned genomes. | T-cell, T cell receptor excision circle, WES data, hg19 or hg38 aligned genomes, | NHLBI U54HL108460; NCATS UL1TR000100; NCI R21CA177519; NCI P30CA023100; NCI U01CA196406; NLM T15LM011271; NIH Office of the Director DP5OD017937; NSF |
PMID:34497419 | Free, Available for download, Freely available | SCR_027742 | , T cell exome TREC, T cell exome T cell Receptor Excision Circle | 2026-02-12 09:48:57 | 0 | ||||||||
|
Oregon National Primate Research Center Resource Report Resource Website 100+ mentions |
Oregon National Primate Research Center (RRID:SCR_008291) | ONPRC | institution | Center that aims to develop biomedical technologies using nonhuman primate (NHP) models. Its goal is to uncover the root causes of various disease and disorders, unlock secrets of the brain, and unleash new methods of diagnostics and treatment. | NPRC, NPRC Consortium, ORIP, enhancement, genetic, aids, animal, biomedical, brain, cancer, cure, delivery, depression, developmental, diabetes, diagnostic, disease, disorder, health, human, model, nonhuman, obesity, premature, primate, reproductive, research, scientific, stem cell, technology, therapy, treatment, vaccine | is listed by: National Primate Research Center Consortium | NIH Office of the Director P51 OD011092; NIH Office of the Director U42 OD023038; NIH Office of the Director U42 OD010426; NIH Office of the Director R24 OD021324 |
Wikidata: Q7101277, Crossref funder ID: 100008143, nif-0000-24358, grid.410436.4, ISNI: 0000 0004 0619 6542 | https://ror.org/05fcfqq67 | SCR_008291 | ONPRC | 2026-02-07 02:07:26 | 100 | ||||||
|
nanoPOTS Resource Report Resource Website |
nanoPOTS (RRID:SCR_017129) | instrument resource | Nanodroplet processing platform for deep and quantitative proteome profiling of 10 to 100 mammalian cells. It enhances efficiency and recovery of sample processing by downscaling processing volumes. | nanodroplet, processing, platform, quantitative, proteome, profiling, analysis, mammalian, cell, small, volume | has parent organization: Pacific Northwest National Laboratory | NIBIB R21 EB020976; NCI R33 CA225248; NIGMS P41 GM103493; NIDDK UC4 DK104167; NIDDK DP3 DK110844; NIH Office Of The Director S10 OD016350; JDRF |
PMID:29491378 | SCR_017129 | 2026-02-07 02:10:00 | 0 | |||||||||
|
Cajun Ejector Resource Report Resource Website |
Cajun Ejector (RRID:SCR_027846) | instrument resource | Shipping Dewar Positional Cooling Device (SDPCD) is 3-D printable vertical cooling device that can assist cryopreservation with various standard cooling rates by use with existing standard nitrogen vapor shipping dewars for on-site sperm cryopreservation for aquatic species.Device could hold 22 French straws (0.25-mL or 0.5-mL) and a quick-release ring design could eject straws directly into a canister inside a dewar by pressing a button after freezing. The final prototypes produced cooling rates of 1 to 68°C/min for 0.25-mL straws, and 3 to 37°C/min for 0.5-mL straws with a material cost of 3.5 USD for a single device | NIH 3D, cooling device, open-hardware, cryopreservation, sperm cryopreservation, aquatic species, 3D print, | NIH Office of the Director R24 OD010441; NIH Officie of the Director R24 OD011120; Louisiana State University ; National Institute of Food and Agriculture ; United States Department of Agriculture |
PMID:36777239 | Free, Available for download, Freely available, | SCR_027846 | , NIAID 3D Cajun Ejector, NIH 3D Cajun Ejector, Shipping Dewar Positional Cooling Device (SDPCD) | 2026-02-07 02:18:05 | 0 | ||||||||
|
Baylor College of Medicine Human Genome Sequencing Center Resource Report Resource Website 50+ mentions |
Baylor College of Medicine Human Genome Sequencing Center (RRID:SCR_013605) | BCM-HGSC | service resource, production service resource, analysis service resource | Center for high-throughput DNA sequence generation and the accompanying analysis. The sequence data generated by the center's machines are analyzed in a complex bioinformatics pipeline, and the data are deposited regularly in the public databases at the National Center for Biotechnology Information (NCBI). | next-generation sequencing, genetic variation, genome, dna sequence, FASEB list |
has parent organization: Baylor University; Texas; USA is parent organization of: Mercury is parent organization of: xAtlas |
NIH Office of the Director R24 OD011173 | nif-0000-10162 | SCR_013605 | Human Genome Sequencing Center, BCM HGSC | 2026-02-11 10:58:47 | 65 | |||||||
|
Microphysiology Systems Database Resource Report Resource Website 1+ mentions |
Microphysiology Systems Database (RRID:SCR_021126) | MPS-Db | data or information resource, database | Open source database used for analyzing and modeling compound interactions with human and animal organ models.Platform for experimental design, data management, and analysis, and to combine experimental data with reference data, to enable computational modeling. Resource for relating in vitro organ model data to multiple biochemical, preclinical, and clinical data sources on in vivo drug effects. | Compound interactions, human organ models, animal organ models, analyzing interactions, modeling interactions, |
is used by: NIH Heal Project is listed by: re3data.org |
NCATS UH3 TR00503; NIH Office of the Director S10 OD01226; U.S. Environmental Protection Agency |
PMID:28781990 | Free, Freely available | SCR_021126 | MPS database | 2026-02-11 11:00:02 | 4 | ||||||
|
Resource for Genetic Epidemiology Research on Adult Health and Aging Resource Report Resource Website 1+ mentions |
Resource for Genetic Epidemiology Research on Adult Health and Aging (RRID:SCR_010472) | GERA | data or information resource, database | Human genetics data from an immense (78,000) and ethnically diverse population available for secondary analysis to qualified researchers through the database of Genotypes and Phenotypes (dbGaP). It offers the opportunity to identify potential genetic risks and influences on a broad range of health conditions, particularly those related to aging. The GERA cohort is part of the Research Program on Genes, Environment, and Health (RPGEH), which includes more than 430,000 adult members of the Kaiser Permanente Northern California system. Data from this larger cohort include electronic medical records, behavioral and demographic information from surveys, and saliva samples from 200,000 participants obtained with informed consent for genomic and other analyses. The RPGEH database was made possible largely through early support from the Robert Wood Johnson Foundation to accelerate such health research. The genetic information in the GERA cohort translates into more than 55 billion bits of genetic data. Using newly developed techniques, the researchers conducted genome-wide scans to rapidly identify single nucleotide polymorphisms (SNPs) in the genomes of the people in the GERA cohort. These data will form the basis of genome-wide association studies (GWAS) that can look at hundreds of thousands to millions of SNPs at the same time. The RPGEH then combined the genetic data with information derived from Kaiser Permanente''s comprehensive longitudinal electronic medical records, as well as extensive survey data on participants'' health habits and backgrounds, providing researchers with an unparalleled research resource. As information is added to the Kaiser-UCSF database, the dbGaP database will also be updated. | genotype, phenotype, genome-wide association study, saliva, dna, male, female, health condition, electronic medical record, single nucleotide polymorphism, adult human, late adult human, gene, genome |
has parent organization: NCBI database of Genotypes and Phenotypes (dbGap) has parent organization: University of California at San Francisco; California; USA |
Aging, Cardiovascular disease, Osteoarthritis, Depressive Disorder, Insomnia, Eye disease, Cancer, Diabetes | NIMH ; NIH Office of the Director ; NIA AG036607 |
Application required, Non-commercial, Data Use Certification Agreement | nlx_157735 | SCR_010472 | Genetic Epidemiology Research on Aging | 2026-02-11 10:58:13 | 9 | |||||
|
Drosophila RNAi Screening Center Resource Report Resource Website 1+ mentions |
Drosophila RNAi Screening Center (RRID:SCR_000733) | DRSC | data or information resource, database | Database that provides free online tools to users to allow the retrieval of information related to the Drosophila genome and allows access to genome-wide and related cell-based screening of Drosophila at Harvard Medical School (for a fee) . Tools available include SnapDragon, and RNAi designer, a heat map tool for viewing screen data, and gene and amplicon search and download tools. The DRSC mainly exists to provide Drosophila genome screening services, including help with assay development and optimization, data and image analysis, and planning of follow-up assays. | genome, screening, drosophila, fly, insect, rnai | has parent organization: Harvard University; Cambridge; United States | NIH Office of the Director R24 OD011176 | PMID:16381918 | nif-0000-02846 | https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources http://flyRNAi.org/cgi-bin/RNAi_screens.pl |
SCR_000733 | Development of Validated Drosophila in vivo RNAi Models of Human Diseases | 2026-02-11 10:56:06 | 2 | |||||
|
SPARC Portal Resource Report Resource Website 100+ mentions |
SPARC Portal (RRID:SCR_017041) | SPARC.science | storage service resource, service resource, data repository | SPARC data repository as of 2023 is an open data repository developed as part of the NIH SPARC initiative and has been used by SPARC funded investigator groups to curate and publish high quality datasets related to the autonomic nervous system. We are thrilled that as of August 2022, SPARC is accepting datasets from investigators that are not funded through the NIH SPARC program. The NIH's Common Fund Stimulating Peripheral Activity to Relieve Conditions (SPARC) program aims to transform our understanding of these nerve-organ interactions and ultimately advance neuromodulation field toward precise treatment of diseases and conditions for which conventional therapies fall short. | Nervous system, periphery, organ, human, FASEB list, repository, curated |
uses: Protocols.io uses: Brain Imaging Data Structure (BIDs) uses: Physiome Model Repository uses: SciGraph uses: o²S²PARC uses: SODA uses: Blackfynn Discover uses: ApiNATOMY uses: Biolucida uses: TissueMaker uses: ScaffoldMaker uses: ScaffoldFitter uses: OpenCOR uses: Pennsieve Data Management Platform uses: InterLex uses: Neurolucida 360 uses: SciCrunch uses: Tissue Mapper uses: Vesselucida 360 uses: DataCite uses: TissueMaker is used by: NIH Heal Project is recommended by: NIDDK Information Network (dkNET) is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is recommended by: National Library of Medicine is related to: SPARC Anatomy Working Group is related to: HORNET CENTER FOR AUTONOMIC NERVE RECORDING AND STIMULATION SYSTEMS is related to: NIH PRECISION Human Pain Network is related to: SCKAN Explorer is related to: SCKANNER works with: SPARC Data Standard has organization facet: o²S²PARC has organization facet: SODA has organization facet: SPARC Anatomy Working Group has organization facet: Blackfynn Discover has organization facet: ApiNATOMY has organization facet: Pennsieve Data Management Platform |
NIH Office of the Director OD025349; NIH Office of the Director OD030213; NIH Office of the Director OD032619; NIH Office of the Director OD030541; NIH Office of the Director OD026585; NIH Office of the Director OD024908; NIH Office of the Director OD025306; NIH Office of the Director OD023849 |
PMID:34248680 DOI:10.1101/2021.02.10.430563 |
Free, Freely available, | DOI:10.26275, r3d100013719 | https://commonfund.nih.gov/sparc https://docs.sparc.science/ https://data.sparc.science/ https://doi.org/10.26275 https://doi.dx/10.26275 https://sparc.science/data?type=dataset https://doi.org/10.17616/R31NJN2V |
SCR_017041 | , SPARC Project, SPARC Repository, Stimulating Peripheral Activity to Relieve Conditions | 2026-02-11 10:59:33 | 115 | ||||
|
MONARCH Initiative Resource Report Resource Website 10+ mentions |
MONARCH Initiative (RRID:SCR_000824) | Monarch | data or information resource, database | Repository of information about model organisms, in vitro models, genes, pathways, gene expression, protein and genetic interactions, orthology, disease, phenotypes, publications, and authors, and ability to navigate multi-scale spatial and temporal phenotypes across in vivo and in vitro model systems in context of genetic and genomic data, using semantics and statistics. Discovery system provides basic and clinical science researchers, informaticists, and medical professionals with integrated interface and set of discovery tools to reveal genetic basis of disease, facilitate hypothesis generation, and identify novel candidate drug targets. Database that indexes authoritative information on experimental models of disease from MGI, RGD and ZFIN. | disease, animal model, phenotype, model organism, in vitro model, gene, pathway, gene expression, protein interaction, genetic interaction, orthology, disease, publication, author, genetic, genomic, model system, genotype, drug, in vivo model |
uses: Animal QTLdb uses: Ensembl Variation uses: Human Phenotype Ontology is used by: NIF Data Federation is related to: Mouse Genome Informatics (MGI) is related to: Rat Genome Database (RGD) is related to: Zebrafish Information Network (ZFIN) is related to: openSNP is related to: Ancora is related to: PhenoGen Informatics is related to: Lifespan Observations Database has parent organization: Oregon Health and Science University; Oregon; USA is parent organization of: monarch-ontologies |
NIH Office of the Director R24 OD011883 | PMID:26269093 | Free, Freely available | r3d100011594, nlx_152525, SCR_001373, nlx_152748 | https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources https://doi.org/10.17616/R31M09 |
SCR_000824 | MONARCH Integrated Disease Model, MONARCH Integrated Disease Models View, MONARCH Disease Models View, The MONARCH Initiative | 2026-02-12 09:43:03 | 12 | ||||
|
microbeMASST Resource Report Resource Website 1+ mentions |
microbeMASST (RRID:SCR_024713) | software resource, web service, data access protocol | Web taxonomically informed mass spectrometry search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging database of over 60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. | Identification of microbial derived metabolites, microbial metabolomics data, microbial metabolite annotation, taxonomy, mass spectrometry search tool, searching tool, bacteria, fungi, metabolomics, microbiome, search known and unknown MS/MS spectra, | is related to: GNPS MASST | NIDDK U24DK133658; NIA U19AG063744; NIGMS 1DP2GM137413; Korean Government ; Austrian Science Fund ; German Research Foundation ; Sao Paulo Research Foundation ; Mexican National Council of Science and Technology ; NIGMS R01GM107550; NSF ; Research Council of Norway ; NIAID R01AI167860; NIDDK T32DK007202; NIGMS 1R01GM132649; NIGMS R35GM142938; NIDDK U01DK119702; NIH Office of the Director S10 OD021750; NLM 1R01LM013115 |
PMID:37577622 | Free, Freely available, | SCR_024713 | 2026-02-12 09:48:03 | 6 | ||||||||
|
Drosophila Genomics Resource Center Resource Report Resource Website 500+ mentions |
Drosophila Genomics Resource Center (RRID:SCR_002845) | DGRC | material resource, cell repository, biomaterial supply resource | Serves Drosophila research community by collecting and distributing DNA clones and vectors; collecting and distributing Drosophila cell lines; developing and testing genomics technologies for use in Drosophila and assisting members of the research community in their use. | RIN, Resource Information Network, expression, gene, array, cell, clone, dna, drosophila, genomics, karyotype, material, microarray, reagent, research, technology, transcriptome, transformation, vector, FASEB list, RRID Community Authority |
is listed by: One Mind Biospecimen Bank Listing is listed by: Resource Information Network has parent organization: Indiana University; Indiana; USA works with: Cellosaurus |
NIH Office of the Director P40 OD010949 | Restricted | nif-0000-25420 | https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources | https://dgrc.cgb.indiana.edu/ | SCR_002845 | Drosophila Genomics Resource Center at Indiana University | 2026-02-12 09:43:28 | 596 | ||||
|
National Swine Resource and Research Center Resource Report Resource Website 50+ mentions |
National Swine Resource and Research Center (RRID:SCR_006855) | NSRRC | organism supplier, material resource, cell repository, biomaterial supply resource | Provides access to critically needed swine models of human health and disease as well as a central resource for reagents, creation of new genetically modified swine, and information and training related to use of swine models in biomedical research. | RIN, Resource Information Network, pig, fetal fibroblast, live animal, tissue, fibroblast, fetus, genetically modified pig, biomaterial manufacture, genome, genotyping, genetics, reproduction, breeding, health monitoring, cryopreservation, phenotyping, consulting, RRID Community Authority |
is used by: Integrated Animals is listed by: One Mind Biospecimen Bank Listing is listed by: Resource Information Network is related to: One Mind Biospecimen Bank Listing has parent organization: University of Missouri; Missouri; USA |
NIH Office of the Director U42 OD011140; NIAID ; NHLBI |
Public, To investigators, Application required | nif-0000-12086 | SCR_006855 | National Swine Resource Research Center | 2026-02-12 09:44:35 | 79 | ||||||
|
Fitness Browser Resource Report Resource Website 1+ mentions |
Fitness Browser (RRID:SCR_018981) | data or information resource, web service, data access protocol, software resource | Web tool for browsing genome wide fitness experiments for diverse bacteria from Deutschbauer lab, the Arkin lab, and collaborators. Collection of mutant phenotypes for bacterial genes of unknown function. | Genome browser, bacteria, mutant phenotype, bacterial genes, unknown function, data | has parent organization: University of California at Berkeley; Berkeley; USA | NCRR S10 RR029668; NCRR S10 RR027303; NIH Office of the Director OD018174; Office of Science of the US Department of Energy |
PMID:29769716 | Free, Freely available | SCR_018981 | 2026-02-12 09:47:07 | 8 | ||||||||
|
nTracer Resource Report Resource Website |
nTracer (RRID:SCR_023032) | software application, image processing software, software resource, data processing software | Software tool as plug-in for ImageJ software. Used for tracing microscopic images. | tracing microscopic images | is a plug in for: ImageJ | Michigan miBRAIN initiative ; NIAID R01AI130303; NSF NSF-1707316; NIMH R01MH110932; NIGMS F31GM116517; NINDS R01NS095367; NIMH P50MH09427; NIH Office of the Director DP2OD006514; NINDS R01NS076467; NINDS U01NS090449; NIGMS P41GM10371; Multidisciplinary University Research Initiative Army Research Office |
PMID:30715234 | Free, Available for download, Freely available | SCR_023032 | 2026-02-12 09:47:46 | 0 | ||||||||
|
ChIP-X Enrichment Analysis 3 Resource Report Resource Website 100+ mentions |
ChIP-X Enrichment Analysis 3 (RRID:SCR_023159) | ChEA3 | software resource, web application | Web based transcription factor enrichment analysis. Web server ranks TFs associated with user-submitted gene sets. ChEA3 background database contains collection of gene set libraries generated from multiple sources including TF-gene co-expression from RNA-seq studies, TF-target associations from ChIP-seq experiments, and TF-gene co-occurrence computed from crowd-submitted gene lists. Enrichment results from these distinct sources are integrated to generate composite rank that improves prediction of correct upstream TF compared to ranks produced by individual libraries. | Transcription Factor, gene sets, transcription factor enrichment analysis, TF-gene co-expression from RNA-seq studies, TF-target associations from ChIP-seq experiments, TF-gene co-occurrence, prediction of correct upstream, | NHLBI U54HL127624; NCI U24CA224260; NIGMS T32GM062754; NIH Office of the Director OT3OD025467 |
PMID:31114921 | Free, Freely available | SCR_023159 | ChIP-X Enrichment Analysis Version 3 (ChEA3) | 2026-02-12 09:48:15 | 108 | |||||||
|
Kinase Enrichment Analysis 3 Resource Report Resource Website 10+ mentions |
Kinase Enrichment Analysis 3 (RRID:SCR_023623) | KEA3 | software resource, web service, data access protocol | Web server application that infers overrepresentation of upstream kinases whose putative substrates are in user inputted list of proteins. Used to analyze data from phosphoproteomics and proteomics studies to predict upstream kinases responsible for observed differential phosphorylations. | overrepresentation of upstream kinases, upstream kinases, upstream kinases substrates, user inputted list of proteins, | has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA | NHLBI U54 HL127624; NCI U24 CA224260; NIGMS T32 GM062754; NIH Office of the Director OT3 OD025467 |
PMID:34019655 | Free, Freely available | SCR_023623 | 2026-02-12 09:47:57 | 11 | |||||||
|
GeneRanger Resource Report Resource Website |
GeneRanger (RRID:SCR_023622) | software resource, web service, data access protocol | Web server application that provides access to processed data about expression of human genes and proteins across human cell types, tissues, and cell lines from several atlases. Used to explore single gene expression across tissues and cell types. | explore single gene expression, gene expression across tissues and cell types, gene expression, |
is related to: TargetRanger has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA |
NCI U24CA264250; NCI U24CA224260; NIDDK R01DK131525; NIH Office of the Director OT2OD030160; NIDDK RC2DK131995; NCI U24CA271114 |
PMID:37166966 | Free, Freely available | SCR_023622 | 2026-02-12 09:47:41 | 0 | ||||||||
|
TargetRanger Resource Report Resource Website 1+ mentions |
TargetRanger (RRID:SCR_023621) | software resource, web service, data access protocol | Web server application that identifies targets from user inputted RNA-seq samples collected from cells we wish to target. By comparing inputted samples with processed RNA-seq and proteomics data from several atlases, TargetRanger identifies genes that are highly expressed in target cells while lowly expressed across normal human cell types, tissues, and cell lines. | identify targets, identify genes, user inputted RNA-seq samples, target cells, proteomics data, human cells, |
is related to: GeneRanger has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA |
NCI U24CA264250; NCI U24CA224260; NIDDK R01DK131525; NIH Office of the Director OT2OD030160; NIDDK RC2DK131995; NCI U24CA271114 |
PMID:37166966 | Free, Freely available | https://maayanlab.github.io/Workshop.io/generanger | SCR_023621 | 2026-02-12 09:48:02 | 2 | |||||||
|
Juicer Resource Report Resource Website 100+ mentions |
Juicer (RRID:SCR_017226) | software resource, software application, data analysis software, data processing software | Software platform for analyzing kilobase resolution Hi-C data. Open source tool for analyzing terabase scale Hi-C datasets. Allowes to transform raw sequence data into normalized contact maps. | analysis, kilobase, resolution, Hi-C, data, terabase, dataset, transform, raw, sequence, normalized, contact, map | has parent organization: Baylor College of Medicine; Houston; Texas | NIH Office of the Director DP2 OD008540; NHLBI U01 HL130010; NSF PHY-1427654; NHGRI HG006193; Welch Foundation ; Cancer Prevention Research Institute of Texas ; NVIDIA Research Center Award ; IBM University Challenge Award ; Google Research Award ; McNair Medical Institute Scholar Award ; President Early Career Award in Science and Engineering ; NHGRI HG003067; PD Soros Fellowship |
PMID:27467249 | Free, Available for download, Freely available | SCR_017226 | 2026-02-12 09:46:51 | 108 |
Can't find your Tool?
We recommend that you click next to the search bar to check some helpful tips on searches and refine your search firstly. Alternatively, please register your tool with the SciCrunch Registry by adding a little information to a web form, logging in will enable users to create a provisional RRID, but it not required to submit.
Welcome to the NIF Resources search. From here you can search through a compilation of resources used by NIF and see how data is organized within our community.
You are currently on the Community Resources tab looking through categories and sources that NIF has compiled. You can navigate through those categories from here or change to a different tab to execute your search through. Each tab gives a different perspective on data.
If you have an account on NIF then you can log in from here to get additional features in NIF such as Collections, Saved Searches, and managing Resources.
Here is the search term that is being executed, you can type in anything you want to search for. Some tips to help searching:
If you are logged into NIF you can add data records to your collections to create custom spreadsheets across multiple sources of data.
Here are the facets that you can filter the data by.
If you have any further questions please check out our FAQs Page to ask questions and see our tutorials. Click this button to view this tutorial again.