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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
pRESTO
 
Resource Report
Resource Website
50+ mentions
pRESTO (RRID:SCR_001782) pRESTO software toolkit, software resource Software toolkit for processing raw reads from high-throughput sequencing of lymphocyte repertoires. lymphocyte, high throughput sequencing, processing, raw reads, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Yale School of Medicine; Connecticut; USA
EMD/Merck/Serono ;
United States-Israel Binational Science Foundation 2009046;
NCRR RR19895;
NLM T15 LM07056;
NIAAA U19AI089992;
NIAAA U19AI050864
PMID:24618469 Free, Freely available SCR_001782 REpertoire Sequencing TOolkit 2026-02-15 09:18:10 70
LOCUSMAP
 
Resource Report
Resource Website
LOCUSMAP (RRID:SCR_000840) LOCUSMAP software application, software resource Software package designed for rapid linkage analysis and map construction of loci with a variety of inheritance modes. (entry from Genetic Analysis Software) gene, genetic, genomic, fortran 90/95, ms-windows, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154434, biotools:locusmap https://bio.tools/locusmap SCR_000840 2026-02-15 09:18:00 0
RightField
 
Resource Report
Resource Website
1+ mentions
RightField (RRID:SCR_002649) RightField software application, software resource An open-source tool for adding ontology term selection to Excel spreadsheets. It is used by a "Template Creator" to create semantically aware Excel spreadsheet templates. The Excel templates are then reused by Scientists to collect and annotate their data; without any need to understand, or even be aware of, RightField or the ontologies used. For each annotation field, RightField can specify a range of allowed terms from a chosen ontology (subclasses, individuals or combinations). The resulting spreadsheet presents these terms to the users as a simple drop-down list. This reduces the adoption barrier for using community ontologies as the annotation is made by the scientist that generated the data rather than a third party, and the annotation is collected at the time of data collection. RightField is a standalone Java application which uses Apache-POI for interacting with Microsoft documents. It enables users to import Excel spreadsheets, or generate new ones from scratch. Ontologies can either be imported from their local file systems, or from the BioPortal ontology repository. Individual cells, or whole columns or rows can be marked with the required ranges of ontology terms and an individual spreadsheet can be annotated with terms from multiple ontologies. annotation, semantic, ontology, term selection, excel, java, bio.tools is listed by: BioPortal
is listed by: FORCE11
is listed by: bio.tools
is listed by: Debian
is related to: SEEK
is related to: Workflow4Ever
has parent organization: University of Manchester; Manchester; United Kingdom
has parent organization: Heidelberg Institute for Theoretical Studies; Heidelberg; Germany
PMID:21622664 Free, Available for download, Freely available biotools:rightfield, nlx_156077 https://bio.tools/rightfield SCR_002649 2026-02-15 09:18:21 3
AltAnalyze - Alternative Splicing Analysis Tool
 
Resource Report
Resource Website
50+ mentions
AltAnalyze - Alternative Splicing Analysis Tool (RRID:SCR_002951) AltAnalyze software application, software resource Software application for microarry, RNA-Seq and metabolomics analysis. For splicing sensitive platforms (RNA-Seq or Affymetrix Exon, Gene and Junction arrays), it will assess alternative exon (known and novel) expression along protein isoforms, domain composition and microRNA targeting. In addition to splicing-sensitive platforms, it provides comprehensive methods for the analysis of other data (RMA summarization, batch-effect removal, QC, statistics, annotation, clustering, network creation, lineage characterization, alternative exon visualization, gene-set enrichement and more). AltAnalyze can be run through an intuitive graphical user interface or command-line and requires no advanced knowledge of bioinformatics programs or scripting. Alternative regulated exons can be subsequently visualized in the context of proteins, domains and microRNA binding sites with the Cytoscape Plugin DomainGraph. analysis, alternative splicing, microarray, calculate, pathway, ontology, domain, microrna, targeting, splicing, microarry, rna-seq, metabolomics, mac osx, windows, ubuntu, cross platform, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Cytoscape
has parent organization: University of California at San Francisco; California; USA
PMID:20513647 Free, Available for download, Freely available nif-0000-30083, OMICS_02250, biotools:altanalyze https://bio.tools/altanalyze SCR_002951 Alternative Splicing Analysis Tool 2026-02-15 09:18:25 81
cortex
 
Resource Report
Resource Website
100+ mentions
cortex (RRID:SCR_002467) cortex software application, software resource Software package with functions that will help researchers plan how many subjects per group need to be included in an MRI-based cortical thickness study to ensure a thickness difference is detected. The package requires cortical thickness mapping and co-registration to be carried out using Freesurfer. The power analyses are implemented in the R software package., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. clinical neuroinformatics, mgh/mgz, magnetic resonance, r, surface analysis, thickness, mri, cortical thickness, morphometry, neuroimaging, power analysis, study design, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: bio.tools
is listed by: Debian
has parent organization: Brain Research Institute
PMID:22807270 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155842, biotools:cortex http://brain.org.au/software/cortex/power
http://www.nitrc.org/projects/cortex
https://bio.tools/cortex
SCR_002467 Sample Size Estimates for Well-Powered Cross-Sectional Cortical Thickness Studies 2026-02-15 09:18:18 374
MAKER
 
Resource Report
Resource Website
1000+ mentions
MAKER (RRID:SCR_005309) software toolkit, software resource Software genome annotation pipeline. Portable and easily configurable genome annotation pipeline. Used to allow smaller eukaryotic and prokaryotic genomeprojects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence based quality values. gene prediction, genome annotation, identifies repeats, aligns ESTs and proteins to genome, data management, genome annotation, annotation, curation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is related to: MAKER Web Annotation Service
has parent organization: University of Utah; Utah; USA
PMID:25501943 SCR_023883, nlx_144363, biotools:maker https://bio.tools/maker
https://github.com/Yandell-Lab/maker
SCR_005309 Maker2, maker 2026-02-15 09:19:03 1422
Unipro UGENE
 
Resource Report
Resource Website
100+ mentions
Unipro UGENE (RRID:SCR_005579) UGENE software toolkit, software resource A multiplatform open-source software to assist molecular biologists without much expertise in bioinformatics to manage, analyze and visualize their data. UGENE integrates widely used bioinformatics tools within a common user interface. The toolkit supports multiple biological data formats and allows the retrieval of data from remote data sources. It provides visualization modules for biological objects such as annotated genome sequences, Next Generation Sequencing (NGS) assembly data, multiple sequence alignments, phylogenetic trees and 3D structures. Most of the integrated algorithms are tuned for maximum performance by the usage of multithreading and special processor instructions. UGENE includes a visual environment for creating reusable workflows that can be launched on local resources or in a High Performance Computing (HPC) environment. UGENE is written in C++ using the Qt framework. The built-in plugin system and structured UGENE API make it possible to extend the toolkit with new functionality. c++, windows, mac os, linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22368248
DOI:10.1093/bioinformatics/bts091
GNU General Public License, v2, Acknowledgement requested OMICS_01022, biotools:ugene https://bio.tools/ugene
https://sources.debian.org/src/ugene/
SCR_005579 2026-02-15 09:19:00 170
Yabi
 
Resource Report
Resource Website
Yabi (RRID:SCR_005359) Yabi service resource, software resource A web-based analytical environment framework for bioinformatics applications that can be customized for a diverse range of -omics applications. The software system is adaptable to a range of both pluggable execution and data backends in an open source implementation. Enabling seamless and transparent access to heterogenous HPC environments at its core, it then provides an analysis workflow environment that can create and reuse workflows as well as manage large amounts of both raw and processed data in a secure and flexible way across geographically distributed compute resources. Yabi can be used via a web-based environment to drag-and-drop tools to create sophisticated workflows. It can also be accessed through the Yabi command line which is designed for users that are more comfortable with writing scripts or for enabling external workflow environments to leverage the features in Yabi. Configuring tools can be a significant overhead in workflow environments. Yabi greatly simplifies this task by enabling system administrators to configure as well as manage running tools via a web-based environment and without the need to write or edit software programs or scripts. grid computing, high performance computing, cloud computing, bioinformatics, pipeline, workflow, command line, python, linux, storage, compute, genomics, transcriptomics, proteomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Murdoch University; Perth; Australia
PMID:22333270 GNU General Public License, v3 OMICS_01148, biotools:yabi https://bio.tools/yabi SCR_005359 2026-02-15 09:18:57 0
HAPLOCLUSTERS
 
Resource Report
Resource Website
HAPLOCLUSTERS (RRID:SCR_007439) HAPLOCLUSTERS software application, software resource Software program designed to detect excess haplotypes sharing in datasets consisting of case and control haplotypes. Excess haplotype sharing can be seen around disease loci in case samples since LD persists longer here than in the controls where LD is persisting only according to the relatedness of the individuals in the population, i.e. the age of the population. (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
Aging nlx_154014, biotools:haploclusters https://bio.tools/haploclusters SCR_007439 2026-02-15 09:19:35 0
LINKAGE
 
Resource Report
Resource Website
LINKAGE (RRID:SCR_007033) software application, software resource Standard software package for genetic linkage called LINKAGE. Genetic linkage analysis is statistical technique used to map genes and find approximate location of disease genes. Genetic linkage analysis, map genes, find location, disease, genes is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: FASTLINK
nlx_154346, biotools:linkage https://bio.tools/linkage
https://gaow.github.io/genetic-analysis-software/l/lcp/
https://gaow.github.io/genetic-analysis-software/l/linkage-general-pedigrees/
http://www.jurgott.org/linkage/LinkagePC SCR_007033 , Linkage Control Program 2026-02-15 09:19:21 0
MULTIMAP
 
Resource Report
Resource Website
10+ mentions
MULTIMAP (RRID:SCR_007168) MULTIMAP software application, software resource Software program for automated construction of genetic maps (entry from Genetic Analysis Software) gene, genetic, genomic, lisp, unix, (sun/compaq-alpha/hp..), bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154013, biotools:multimap https://bio.tools/multimap http://compgen.rutgers.edu/Multimap/ SCR_007168 2026-02-15 09:19:29 27
SIBMED
 
Resource Report
Resource Website
1+ mentions
SIBMED (RRID:SCR_007495) SIBMED software application, software resource Software application that identifies likely genotyping errors and mutations for a sib pair in the context of multipoint mapping. (entry from Genetic Analysis Software) gene, genetic, genomic, fortran 77, ms-windows, unix, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:sibmed, nlx_154043 https://bio.tools/sibmed SCR_007495 SIBling Mutation and Error Detection 2026-02-15 09:19:46 1
COEUS
 
Resource Report
Resource Website
1+ mentions
COEUS (RRID:SCR_006287) COEUS software application, software resource A semantic web-powered knowledge management framework, aiming at a streamlined application development cycle and following a semantic web in a box approach. The framework provides a single package including advanced data integration and triplification tools, base ontologies, a web-oriented engine and a flexible exploration API. Resources can be integrated from heterogeneous sources, including CSV and XML files or SQL and SPARQL query results, and mapped directly to one or more ontologies. Advanced interoperability features include REST services, a SPARQL endpoint and LinkedData publication. These enable the creation of multiple applications for web, desktop or mobile environments, and empower a new knowledge federation layer. It is targeted at rapid application deployment of new applications in any research field, supported by a comprehensive integration engine and an advanced data distribution API. data integration, interoperability, ontology, semantic web, bioinformatics, biomedical, semantic web framework, rapid application deployment, linked data, web service, biomedical application, biomedical semantics, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Aveiro; Aveiro; Portugal
PMID:23244467 Open unspecified license biotools:coeus, nlx_151933 https://bio.tools/coeus SCR_006287 2026-02-15 09:19:13 6
PubCrawler
 
Resource Report
Resource Website
1+ mentions
PubCrawler (RRID:SCR_008235) service resource, software resource PubCrawler is a free alerting service that scans daily updates to the NCBI Medline (PubMed) and GenBank databases. PubCrawler helps keeping scientists informed of the current contents of Medline and GenBank, by listing new database entries that match their research interests. The free PubCrawler web service has been operating for five years and so far has brought literature and sequence updates to over 22 000 users. It provides information on a personalized web page whenever new articles appear in PubMed or when new sequences are found in GenBank that are specific to customized queries. The server also acts as an automatic alerting system by sending out short notifications or emails with the latest updates as soon as they become available. PubCrawler searches the NCBI PubMed (Medline) and Entrez (GenBank) databases daily using search parameters (keywords, author names, etc.) specified by the user. There is no limit on the number of searches that can be carried out. Previous search hits are stored and only the newest PubMed or GenBank records are shown each day. The results are presented as an HTML Web page, similar to the results of an NCBI PubMed or Entrez query. This Web page can be located on our computer (the PubCrawler WWW-Service), on your computer (the stand-alone program), or you can receive it via e-mail (set this up using the PubCrawler WWW-Service). The Web page sorts the results into groups of PubMed/GenBank entries that are zero-days-old, 1-day-old, 2-days-old, etc., up to a user-specified age limit. Sponsors: Development of PubCrawler was supported by EMBnet training tools, bio.tools is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
biotools:pubcrawler, nif-0000-21345 https://bio.tools/pubcrawler SCR_008235 PubCrawler 2026-02-15 09:19:29 9
ASPEX
 
Resource Report
Resource Website
1+ mentions
ASPEX (RRID:SCR_008414) ASPEX software application, software resource A set of programs for performing multipoint exclusion mapping of affected sibling pair data for discrete traits. (entry from Genetic Analysis Software) gene, genetic, genomic, c, tcl, perl, (the graphic script requires xmgr, available from ftp://ftp.teleport.com/pub/users/pturner/acegr), unix, (solaris/sunos/irix/osf-1), linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154234, biotools:aspex https://bio.tools/aspex SCR_008414 Affected Sib Pairs EXclusion map 2026-02-15 09:19:49 9
ALBERT
 
Resource Report
Resource Website
10+ mentions
ALBERT (RRID:SCR_009037) ALBERT software application, software resource Software application that estimates genotype relative risks, genotyping error rates and population risk allele frequencies from marker genotype data in case-parent trios. ALBERT uses the distribution of trio marker genotypes to compute maximum likelihood estimates for the parameters. (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
biotools:albert, nlx_154002 https://bio.tools/albert SCR_009037 A Likelihood Based Estimation of Risk in Trios 2026-02-15 09:20:01 47
FastTree
 
Resource Report
Resource Website
5000+ mentions
FastTree (RRID:SCR_015501) source code, software resource Source code that infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. It uses the Jukes-Cantor or generalized time-reversible (GTR) models of nucleotide evolution and the JTT, WAG, or LG models of amino acid evolution. phylogenetic tree, phylogenetic tree creation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: VeryFastTree
PMID:19377059
DOI:10.1371/journal.pone.0009490
biotools:fasttree, OMICS_14703 https://bio.tools/fasttree
https://sources.debian.org/src/fasttree/
SCR_015501 2026-02-15 09:20:54 5774
lme4
 
Resource Report
Resource Website
100+ mentions
lme4 (RRID:SCR_015654) source code, software resource Software R package. Fit linear and generalized linear mixed-effects models. The models and their components are represented using S4 classes and methods. The core computational algorithms are implemented using the 'Eigen' C++ library for numerical linear algebra and 'RcppEigen' "glue." linear mixed-effects model, s4 class, eigen c++ library, r package, r, bio.tools is listed by: CRAN
is listed by: bio.tools
is listed by: Debian
works with: R package: lmerTest
Free, Available for download biotools:lme4 https://cran.r-project.org/package=lme4
https://github.com/lme4/lme4/
https://bio.tools/lme4
SCR_015654 lme4, lme4.0, lme4: Linear Mixed-Effects Models using 'Eigen' and S4, lme4: Linear Mixed-Effects Models, R package: lme4 2026-02-15 09:21:35 327
TomoMiner
 
Resource Report
Resource Website
1+ mentions
TomoMiner (RRID:SCR_015045) source code, software resource Software platform for large-scale cryo electron subtomogram classification, alignment, and averaging. analysis platform, cryo electron subtomogram, subtomogram classification, subtomogram alignment, subtomogram averaging, subtomogram analysis, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Southern California; Los Angeles; USA
requires: Python Programming Language
requires: NumPy
requires: SciPy
requires: LAPACK linear algebra library
requires: Cython C-Extensions for Python
Available for download biotools:tomominer https://bio.tools/tomominer SCR_015045 2026-02-15 09:21:05 3
MetaP
 
Resource Report
Resource Website
10+ mentions
MetaP (RRID:SCR_014686) computational hosting, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 5,2023. Software tool for processing in metabolomics experiments., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. metabolomics, metabolomics tool, server, data analysis, processing, computational hosting, bio.tools is listed by: Metabolomics Workbench
is listed by: bio.tools
DOI:10.1155/2011/839862 THIS RESOURCE IS NO LONGER IN SERVICE biotools:metap https://bio.tools/metap SCR_014686 metap, MetaP Server 2026-02-15 09:20:58 14

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