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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MCScan
 
Resource Report
Resource Website
10+ mentions
MCScan (RRID:SCR_017650) software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software package to simultaneously scan multiple genomes to identify homologous chromosomal regions and subsequently align these regions using genes as anchors.Used to identify conserved gene arrays both within same genome and across different genomes. Command line program to wrap dagchainer and combine pairwise results into multi alignments in column format. Simultaneously, scan, multiple, genome, identify, homologous, chromosomal, region, align, gene, anchor, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Georgia; Georgia; USA
Free, Available for downoad, Freely available biotools:MCScan http://chibba.agtec.uga.edu/duplication/mcscan/
https://bio.tools/MCScan
SCR_017650 Multiple Collinearity Scan 2026-02-16 09:49:17 37
Blobtools
 
Resource Report
Resource Website
100+ mentions
Blobtools (RRID:SCR_017618) software application, data processing software, data analytics software, data visualization software, software resource Software tool as modular command line solution for visualisation, quality control and taxonomic partitioning of genome datasets. Used for interrogation of genome assemblies. Assists in primary partitioning of data, leading to improved assemblies, and screening of final assemblies for potential contaminants. Modular, command, line, solution, visualisation, quality, control, taxonomic, partitioning, genome, dataset, genome assembly, screening, contaminant, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: BlobTools2
James Hutton Institute/Edinburgh University School of Biological Sciences fellowship ;
BBSRC
DOI:10.12688/f1000research.12232.1 Free, Available for download, Freely available biotools:blobtools https://github.com/DRL/blobtools
https://bio.tools/blobtools
SCR_017618 BlobTools 2026-02-16 09:49:17 199
Ngmlr
 
Resource Report
Resource Website
10+ mentions
Ngmlr (RRID:SCR_017620) NGMLR software application, data processing software, image analysis software, software resource, alignment software Software tool as long read mapper designed to align PacBio or Oxford Nanopore reads to reference genome and optimized for structural variation detection. Long, read, mapper, align, PacBio, Oxford Nanopore, read, reference, genome, structural, variantion, detection, bio.tools is listed by: bio.tools
is listed by: Debian
National Science Foundation ;
NHGRI R01 HG006677;
NHGRI UM1 HG008898
PMID:29713083 Free, Available for download, Freely available biotools:ngmlr https://bio.tools/ngmlr SCR_017620 coNvex Gap-cost alignMent for Long Reads 2026-02-16 09:49:16 31
PatchDock
 
Resource Report
Resource Website
50+ mentions
PatchDock (RRID:SCR_017589) software application, web service, data access protocol, software resource, simulation software Web server for molecular docking. Performs structure prediction of protein–protein and protein–small molecule complexes. Molecular docking algorithm based on shape complementarity principles. Molecular, docking, structure, prediction, protein, molecule, shape, complex, bio.tools is listed by: Debian
is listed by: bio.tools
Israel Science Foundation ;
Hermann Minkowski-Minerva Center for Geometry at Tel Aviv University ;
Israeli Ministry of Science ;
National Cancer Institute ;
NIH
PMID:15980490 Free, Freely available biotools:patchdock https://bio.tools/patchdock SCR_017589 2026-02-16 09:49:16 85
Fcirc
 
Resource Report
Resource Website
1+ mentions
Fcirc (RRID:SCR_018090) Fcirc data processing software, software application, software resource, workflow software Software Python pipeline for linear and circular RNAs of known fusions exploration. Pipeline for exploring linear transcripts and circRNAs of known fusions based on RNA-Seq data. Known fusion genes are from multiple databases like COSMIC, ChimerDB, TicDB, FARE-CAFE and FusionCancer or user-added gene-pairs. Fusion gene, linear and circular RNA, fusion exploration, RNAseq data, linear transcript, circRNA, gene, data, pipeline, bio.tools uses: HISAT2
uses: SAMTOOLS
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China 31771469 ;
National Natural Science Foundation of China 31571363 ;
National Natural Science Foundation of China 81573023 ;
National Key Research and Development Program 2017YFC0908500
Free, Available for download, Freely available biotools:Fcirc https://bio.tools/Fcirc SCR_018090 Comprehensive Pipeline for Exploration of Fusion Linear and Circular RNAs 2026-02-16 09:49:25 2
shinyGEO
 
Resource Report
Resource Website
shinyGEO (RRID:SCR_017605) analysis service resource, web application, software resource, production service resource, service resource Web based tool to download gene expression datasets from GEO in order to perform differential expression and survival analysis for gene of interest. Produces publication ready graphics and generates R code ensuring that all analyses are reproducible. Web based application for analyzing gene expression omnibus datasets. Gene, expression, dataset, GEO, differencial, analysis, gene, graphic, omnibus, data, bio.tools uses: Shiny
is listed by: Debian
is listed by: bio.tools
has parent organization: Eastern Connecticut State University; Connecticut; United States
works with: Gene Expression Omnibus (GEO)
Google Summer of Code PMID:27503226 Free, Available for download, Freely available biotools:shinygeo https://gdancik.github.io/shinyGEO/
https://bio.tools/shinygeo
SCR_017605 2026-02-16 09:49:17 0
refgenie
 
Resource Report
Resource Website
1+ mentions
refgenie (RRID:SCR_017574) service resource, software application, software resource, data management software Software tool to organize, retrieve, and share genome analysis resources. Reference genome assembly asset manager. In addition to genome indexes, can manage any files related to reference genomes, including sequences and annotation files. Includes command line interface and server application that provides RESTful API, so it is useful for both tool development and analysis. Organize, retrive, share, genome, analysis, reference, assembly, asset, manager, sequence, annotation, file, command, line, interface, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/698704 Free, Available for download, Freely available biotools:Refgenie https://bio.tools/Refgenie SCR_017574 reference genome manager 2026-02-16 09:49:16 6
CRISPy-web
 
Resource Report
Resource Website
10+ mentions
CRISPy-web (RRID:SCR_017970) data access protocol, software resource, web service Web tool to design sgRNAs for CRISPR applications. Web tool based on CRISPy to design sgRNAs for any user-provided microbial genome. Implemented as standalone web application for Cas9 target prediction. Design, sgRNA, CRISP, microbial, genome, Cas9, target, prediction, data, guide, single, editing, bio.tools is listed by: bio.tools
is listed by: Debian
Novo Nordisk Foundation PMID:29062934 Free, Freely available biotools:crispy https://bio.tools/crispy SCR_017970 single guide RNA desing 2026-02-16 09:49:23 25
PAFScaff
 
Resource Report
Resource Website
1+ mentions
PAFScaff (RRID:SCR_017976) software application, data processing software, sequence analysis software, data analysis software, software resource Software as Pairwise mApping Format reference based Scaffold anchoring and super scaffolding tool. Dsigned for mapping genome assembly scaffolds to closely related chromosome level reference genome assembly. Pairwise, mapping, reference, scaffold, genomics, scaffolding, assembly, genome, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:PAFScaff https://github.com/slimsuite/pafscaff/blob/master/PAFScaff.md
https://slimsuite.github.io/pafscaff/
https://bio.tools/PAFScaff
SCR_017976 Pairwise mApping Format reference-based Scaffold 2026-02-16 09:49:23 4
CandiMeth
 
Resource Report
Resource Website
1+ mentions
CandiMeth (RRID:SCR_017974) CandiMeth software application, data processing software, data analysis software, analysis service resource, software resource, production service resource, service resource Software tool for visualisation and quantification of DNA methylation at candidate features. DNA, methylation, candidate feature, visualisation, quantification, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
Medical Research Council ;
ESRC/BBSRC
Free, Freely available biotools:CandiMeth http://bit.do/candimeth
https://usegalaxy.org/u/sarajayne-thursby/w/candimeth-8
https://bio.tools/CandiMeth
SCR_017974 CANDIdate feature METHylation 2026-02-16 09:49:24 2
Warp
 
Resource Report
Resource Website
1+ mentions
Warp (RRID:SCR_018071) software application, data processing software, data analysis software, software resource, data acquisition software Software tool that automates all preprocessing steps of cryo-EM data acquisition and enables real-time evaluation. Corrects micrographs for global and local motion, estimates local defocus and monitors key parameters for each recorded micrograph or tomographic tilt series in real time. Software includes deep-learning-based models for accurate particle picking and image denoising. Automating preprocessing step, cryo EM data acquisition, micrograph correction, particle picking, image denoising, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/s41592-019-0580-y Free, Available for download, Freely available BioTools:Warp, biotools:Warp https://bio.tools/Warp
https://bio.tools/Warp
https://bio.tools/Warp
SCR_018071 2026-02-16 09:49:25 7
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) software application, web service, data access protocol, software resource, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-16 09:49:26 149
ChiCMaxima
 
Resource Report
Resource Website
1+ mentions
ChiCMaxima (RRID:SCR_018178) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Pipeline for analyzing and identificantion of chromatin loops in CHi-C promoters data. Used to capture Hi-C visualization and interaction calling. Chromatin loop, CHi-C promoter, data, Hi-C visualization, interaction calling, data, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31118054 Free, Freely available biotools:ChiCMaxima https://bio.tools/ChiCMaxima SCR_018178 2026-02-16 09:49:27 2
PlotTwist
 
Resource Report
Resource Website
10+ mentions
PlotTwist (RRID:SCR_018331) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Web application for plotting and annotating continuous data. Open source web app for plotting and annotating time series data. Used to inspect data and generate publication quality visualizations. Available options for plotting include lineplot, small multiples and heatmap, summary statistics and inferential statistics. Plotting continuous data, annotating continuous data, data visualization, time series data, line plot, small multiples, heatmap, statistic, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:31929523 Free, Freely available biotools:Plottwist, BioTools:PlotTwist https://github.com/JoachimGoedhart/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
https://bio.tools/PlotTwist
SCR_018331 PlotTwist Shiny 2026-02-16 09:49:27 10
CRISPRdirect
 
Resource Report
Resource Website
100+ mentions
CRISPRdirect (RRID:SCR_018186) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Software for designing CRISPR/Cas guide RNA with reduced off target sites. Used for rational design of CRISPR/Cas target. Web server for selecting rational CRISPR/Cas targets from input sequence. Server currently incorporates genomic sequences of human, mouse, rat, marmoset, pig, chicken, frog, zebrafish, Ciona, fruit fly, silkworm, Caenorhabditis elegans, Arabidopsis, rice, Sorghum and budding yeast. CRISP/Cas guide RNA, reduced off target site, design of CRISP/Cas target, selecting rational target, sequence, genomic sequence, RNA, bio.tools is listed by: Debian
is listed by: bio.tools
Japan Science and Technology Agency ;
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan
PMID:25414360 Free, Freely available biotools:CRISPRdirect https://bio.tools/CRISPRdirect SCR_018186 2026-02-16 09:49:27 452
HingeProt
 
Resource Report
Resource Website
1+ mentions
HingeProt (RRID:SCR_018136) service resource, data access protocol, software resource, web service Web server for predicting rigid protein parts and flexible hinge regions connecting them in native topology of protein chains by employing elastic network (EN) models. Automated prediction of hinges in protein structures. Predicting protein hinges, flexible hinge region, native topology, rigid protein part, elastic network model, protein structure, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:17847101 Free, Available for download, Freely available biotools:hingeprot https://bio.tools/hingeprot SCR_018136 2026-02-16 09:49:24 4
SymPy
 
Resource Report
Resource Website
1+ mentions
SymPy (RRID:SCR_018417) software resource, software toolkit, software library Software Python library for symbolic mathematics. It aims to become full featured computer algebra system (CAS) while keeping code as simple as possible in order to be comprehensible and easily extensible. Python, Python library, symbolic mathematics, computer algebra system, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:SymPy https://bio.tools/SymPy SCR_018417 2026-02-16 09:49:28 9
smashpp
 
Resource Report
Resource Website
1+ mentions
smashpp (RRID:SCR_018307) software application, data processing software, data visualization software, data analysis software, software resource Software tool to find and visualize rearrangements in DNA sequences. Find sequence rearrangement, visualize sequence rearrangement, DNA, DNA sequence, DNA sequence rearrangement, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:smashpp, BioTools:smashpp https://bio.tools/smashpp
https://bio.tools/smashpp
https://bio.tools/smashpp
SCR_018307 Smash++ 2026-02-16 09:49:26 2
Machado
 
Resource Report
Resource Website
1+ mentions
Machado (RRID:SCR_018428) application programming interface, web service, data access protocol, software resource, data or information resource Software tool as framework to store, search and visualize biological data. Django instance provides data management, visualization, and searching functionalities to Chado databases. Resulting object-relational framework enables users, not only to set up local instance containing data regarding their organisms of interest, but also to develop all sorts of tools by accessing open source code. Python, genomics, data, framework, data visualization, data management, Chado datbase, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Plant Co-expression Annotation Resource
Embrapa Free, Available for download, Freely available biotools:machado https://bio.tools/machado SCR_018428 2026-02-16 09:49:28 2
GPS-SUMO
 
Resource Report
Resource Website
1+ mentions
GPS-SUMO (RRID:SCR_018261) web service, data access protocol, software resource, portal, service resource, data or information resource Web service for prediction of SUMOylation sites and SUMO-interaction motifs in proteins by CUCKOO Workgroup. Small ubiquitin like modifier, SUMOs, sumoylation, covalently modified protein, group prediction system, site prediction, interaction motif in protein, bio.tools is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
National Basic Research Program ;
Guangdong Natural Science Funds for Distinguished Young Scholar ;
Zhujiang Nova Program of Guangzhou ;
International Science and Technology Cooperation Program of China
PMID:24880689 Restricted biotools:gps-sumo http://sumosp.biocuckoo.org/online.php
https://bio.tools/gps-sumo
SCR_018261 Group-based Prediction System -Small Ubiquitin-like MOdifiers, Small Ubiquitin-like MOdifiers sp, GPS-SUMO 2.0, SUMOsp, GPS Small Ubiquitin-like MOdifiers, Group-based Prediction System-SUMO 2026-02-16 09:49:28 2

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