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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.mmpc.org/shared/showCenterCore.aspx?id=45
Core responsible for oversight and coordination of all aspects of the scientific and administrative operations of the MMPC-UCD. This includes providing full customer support services, overseeing management and operation of the Center, and foster interactions and synergism among cores and research projects. The ultimate goal of the Core is to ensure that the Center effectively and efficiently delivers services to its users.
Proper citation: MMPC-University of California Davis Administrative Core (RRID:SCR_015362) Copy
http://sph.unc.edu/norc/research-partnerships/
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 23,2019. Center that provides bioinformatics and metabolomics support to UNC members for nutrition and obesity-related clinical and translational research.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Research Facilitation Program (RRID:SCR_015480) Copy
http://www.uc.edu/labs/mmpc/select-test/cardiovascular-services.html
Core that offers services in testing animal physiological variables such as blood pressure, heart rate, pulse pressure and activity after inserting a PA-C10 telemetry device in them.
Proper citation: MMPC-University of Cincinnati Medical Center Cardiovascular and Renal Function Core (RRID:SCR_015360) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/assay-core
Core that provides Ussing chamber capabilities and expertise for testing vectoral anion transport in polarized airway epithelial monolayers, and florescent dye-based methods for evaluating CFTR activity in cells grown on coverslips. The core also performs immunolocalization for proteins relevant to cystic fibrosis pathogenesis.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Assay Core (RRID:SCR_015407) Copy
http://depts.washington.edu/cfrtc/inflammation/
Core whose objective is to obtain information on relevant parameters of the host response that is unique to cystic fibrosis using a variety of techniques, including in vivo and in vitro imaging, immunohistochemistry, imaging and image analysis, cells and bacteria in tissues, and quantification of chemokines, cytokines, and other factors with ELISA.
Proper citation: Cystic Fibrosis Center - University of Washington Host Response Core (RRID:SCR_015405) Copy
http://depts.washington.edu/cfrtc/administrative-core/
Core that manages and oversees the UW CFRTC and its cores and pilot and feasibility programs.
Proper citation: Cystic Fibrosis Center - University of Washington Administrative and Enrichment Core (RRID:SCR_015408) Copy
http://umassmed.edu/umpc/cores/cardiovascular/
Core that provides phenotyping of cardiovascular system in mouse models of metabolic disease and an easily accessible cardiovascular disease model pipeline. It services include 2D and M-mode echocardiography in lightly-anesthetized mice to non-invasively assess cardiac structure and function using state-of-the-art high-frequency, high-resolution in vivo digital imaging platform as well as Transverse Aortic Constriction (TAC) model to investigate pressure-overload hypertrophy, congestive heart failure, and aortic stenosis.
Proper citation: MMPC-University of Massachusetts Medical School Cardiovascular Core (RRID:SCR_015375) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=50
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 16,2025. Core whose mission is to provide analytical tools to investigators to permit determination of the structure of the microbiome in mouse models of disease and assistance in the cultivation of microbes that will permit hypothesis testing in murine models including the germfree animals that are available in the Animal Care Core.
Proper citation: MMPC-University of Michigan Medical School Microbiome Core (RRID:SCR_015378) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core
Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.
Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy
https://labnodes.vanderbilt.edu/resource/view/id/10820/community_id/1418
Core that consists of three subcores: Hormone Assay and Analytical Services, Lipids, Lipoproteins, and Atherosclerosis, and Mouse Pathology. The Hormone Assay and Analytical Services provides analyses that facilitate research in diabetic, cardiovascular, and obese animal models. Lipids and Lipoproteins Subcore provides quantitative and qualitative measurements of plasma and tissue lipids and lipoproteins to researchers who use mice to study atherosclerosis, dyslipidemia, diabetes, obesity, hypertension, and other metabolic diseases. Mouse Pathology services include standard pathology testing in hematology, clinical chemistry, parasitology, microbiology, serology, molecular diagnostics, necropsy, and research histology and pathology expertise and counseling.
Proper citation: MMPC-Vanderbilt University School of Medicine Analytical Resources Core (RRID:SCR_015379) Copy
http://www.uc.edu/labs/mmpc/select-test/energy-balance.html
Core that specializes in total body/carcass analysis, measurement of oxygen consumption and carbon dioxide production, meal pattern analysis, and feeding mass/bouts, drinking volume, VO2 and VCO2.
Proper citation: MMPC-University of Cincinnati Medical Center Energy Metabolism Food Intake and Body Weight Regulation Core (RRID:SCR_015371) Copy
http://www.med.unc.edu/cgibd/cores/advanced-analytics
Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy
http://www.med.unc.edu/cgibd/cores/large-animal-core
Core facility that provides consultation and procedural expertise on development on novel models of relevant digestive diseases in large animals.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Large Animal Models Core (RRID:SCR_015619) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html
Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html
Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy
https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material
Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.
Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/integratedPhysiology.html
Core facility that provides Center investigators and their laboratories the tools and advice needed to establish and study mouse (including transgenic and knockout) and human (i.e. GI organoids) physiology of GI disease.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Integrated Physiology Core (RRID:SCR_015591) Copy
http://www.med.umich.edu/mgpc/cores/pil.htm
Core facility whose services include the following programs: Imaging Core Program, Proteomics Core Program, Protein Folding Core Program, and Consultation.
Proper citation: University of Michigan Center for Gastrointestinal Research Protein Localization, Identification and Folding Core (RRID:SCR_015609) Copy
http://www.med.umich.edu/mgpc/cores/maic.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.
Proper citation: University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core (RRID:SCR_015611) Copy
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